Search results for "sperm"

showing 10 items of 658 documents

Hemodynamic effects of experimental testicular torsion.

1987

Experimental testicular torsion must be used for certain studies of clinical relevance, but most experimental models either do not provide hemodynamic alteration comparable to the clinical situation or cannot guarantee reproducibility. Using a rat model arterial perfusion and hemorrhagic infarction were correlated to the degree of both intra- and extravaginal testicular torsion. Arterial inflow was measured sequentially with radiolabelled microspheres, hemorrhagic infarction was judged by the increase of testicular weight. Maximal hemorrhagic infarction and reproducible values were found when the spermatic cord was twisted together with the tunica vaginalis for 360 degrees-540 degrees.

NephrologyMaleendocrine systemmedicine.medical_specialtyUrologyInfarctionHemodynamicsHemorrhageSpermatic cordInternal medicineTestismedicineTesticular torsionAnimalsHumansSpermatic Cord TorsionClinical significancecardiovascular diseasesSpermatic Cord Torsionbusiness.industryTunica vaginalisHemodynamicsRats Inbred StrainsArteriesmedicine.diseaseRatsDisease Models Animalmedicine.anatomical_structureInfarctionAnesthesiacardiovascular systemCardiologybusinessUrological research
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Reciprocal regulation of endothelial nitric-oxide synthase and NADPH oxidase by betulinic acid in human endothelial cells.

2007

Nitric oxide (NO) produced by endothelial NO synthase (eNOS) is a protective principle in the vasculature. Many cardiovascular diseases are associated with reduced NO bioactivity and eNOS uncoupling due to oxidative stress. Compounds that reverse eNOS uncoupling and increase eNOS expression are of therapeutic interest. Zizyphi Spinosi semen (ZSS) is one of the most widely used traditional Chinese herbs with protective effects on the cardiovascular system. In human umbilical vein endothelial cells (HUVEC) and HUVEC-derived EA.hy 926 cells, an extract of ZSS increased eNOS promoter activity, eNOS mRNA and protein expression, and NO production in a concentration- and time-dependent manner. Maj…

Nitric Oxide Synthase Type IIIBlotting Westernmedicine.disease_causeNitric OxideGene Expression Regulation EnzymologicNitric oxidechemistry.chemical_compoundEnosBetulinic acidmedicineHumansNitric Oxide DonorsEnzyme InhibitorsBetulinic AcidCyclic GMPCells CulturedPharmacologyNADPH oxidaseBetulinbiologyDose-Response Relationship DrugReverse Transcriptase Polymerase Chain ReactionNOX4AcetophenonesEndothelial CellsNADPH OxidasesZiziphusSaponinsbiology.organism_classificationTriterpenesNG-Nitroarginine Methyl EsterchemistryBiochemistryNADPH Oxidase 4biology.proteinMolecular MedicineSpermineP22phoxPentacyclic TriterpenesReactive Oxygen SpeciesOxidative stressDrugs Chinese HerbalThe Journal of pharmacology and experimental therapeutics
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Zvaigžņotā Debess: 2004/05, Ziema

2004

Contents: Ņ.Ozoliņa. Earthquakes in Latvia ; I.Daube. Space Craft “Ranger-7” ; M. Gailis. Moon Investigation in Riga ; J.Tambergs. Problems of Dialogue between Quantum Mechanics and Theology (concluded) ; Z Alksne, A.Alksnis. Ultra-Cool Dwarf Pair Weighed ; A.Balklavs. Successful Hunt of Protostars ; A.Balklavs. Silhouette of a Black Hole ; A.Balklavs. A Distant Giant Quasar ; A.Balklavs. Cosmic Objects in Captivating Photos – 3 ; J.Freimanis. Extragalactic Planetary Nebulae ; J.Jaunbergs. Cassini Enters the Saturnian System ; D.Krieviņš. Space Launchers of Early XXI Century. The Commonwealth of Independent States (CIS) ; J.Bārzdiņš. Professor Rusins-Martins Freivalds on the Path of Science…

Novembra kāvi Baltijas debesīsGalēji auksto punduru sistēma 2MASSW J0746425+2000321Herbiga-Haro objekti HH-30 HH-34 HH-47Krustvārdu mīklaLīgatnes meteorīts – hipotēzeProtozvaigznesPlanetārie miglāji – NGC 2392 (Eskimosa miglājs) NGC 6369 (Spociņa miglājs)Starptautiskā komandu olimpiāde “Baltijas ceļš – 2003” – uzdevumu atrisinājumiRisina lasītājsNASA Genesis – Saules vēja paraugiLU profesors Rūsiņš-Mārtiņš FreivaldsZemestrīces LatvijāBlumbaha spoguļteleskops BSTPirmās galaktikasCassini misija Saturna sistēmāJakobs Juliuss ZeibotsJupitera pavadoņa Jo putekļiRīgas topogrāfiskā uzmērīšanaSavādnieki eksaktajās zinātnēs – Dž.Maksvels O.Sevisaids H.Hercs V.Pauli V.Heizenbergs B.Mandelbrots A.Vītols J.Vītols G.Šipovs A.AkimovsMeteorītu panspermijaPlanetārie miglāji N52 N66 N192 SMP93 Lielajā Magelāna MākonīVenēras un Merkura aizklāšanāsKosmiskie transportlīdzekļi – NVSAstronomiskās parādības - 2005Melnais caurums – siluetsKalenaisa – “Hebridu Stounhendža”Planētu redzamības kompleksā diagramma 2005Zvaigžņu lietus novembrīESA Smart-1Astronomiskās parādības - 2004Kvantu mehānika un teoloģijaMilzu kvazārs J1432+158Londonas universitātes Berkbeka koledža
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Saponins from the Roots of Nylandtia spinosa

2007

From the roots of Nylandtia spinosa, four new triterpene saponins, 3- O-beta- d-glucopyranosylpresenegenin 28- O-beta- d-galactopyranosyl-(1-->4)-[alpha- l-arabinopyranosyl-(1-->3)]-beta- d-xylopyranosyl-(1-->4)-[beta- d-apiofuranosyl-(1-->3)]-alpha- l-rhamnopyranosyl-(1-->2)-beta- d-fucopyranosyl ester ( 1), 3- O-beta- d-glucopyranosylpresenegenin 28- O-beta- d-galactopyranosyl-(1-->4)-[alpha- l-arabinopyranosyl-(1-->3)]-beta- d-xylopyranosyl-(1-->4)-alpha- l-rhamnopyranosyl-(1-->2)-beta- d-fucopyranosyl ester ( 2), 3- O-beta- d-glucopyranosylpresenegenin 28- O-beta- d-apiofuranosyl-(1-->4)-[beta- d-galactopyranosyl-(1-->2)]-beta- d-xylopyranosyl-(1-->4)-alpha- l-rhamnopyranosyl-(1-->2)-be…

Nylandtia spinosaCoumaric AcidsSpermidineStereochemistrySaponinPharmaceutical SciencePharmacognosyPlant RootsAnalytical ChemistryInhibitory Concentration 50TriterpeneDrug DiscoveryHumansNuclear Magnetic Resonance BiomolecularPharmacologychemistry.chemical_classificationPlants MedicinalMolecular StructureChemistryOrganic ChemistryGlycosideTenuifolinSaponinsTriterpenesTerpenoidPolygalaceaeHuman colon cancerComplementary and alternative medicineMolecular MedicineDrug Screening Assays AntitumorJournal of Natural Products
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Sperm p53 concentration: a potential new biomarker for environmental pollution. Preliminary data. (EcoFoodFertility Project)

2019

OncologyBiomarkermedicine.medical_specialtybusiness.industryUrologyInternal medicineMedicineBiomarker (medicine)Environmental pollutionComputational biologyToxicologybusinessSpermReproductive Toxicology
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Hundreds of nuclear and plastid loci yield novel insights into orchid relationships.

2021

Pérez-Escobar, Oscar Alejandro, Dodsworth, Steven, Bogarín, Diego, Bellot, Sidonie, Balbuena, Juan A, Schley, Rowan J, Kikuchi, Izai A, Morris, Sarah K, Epitawalage, Niroshini, Cowan, Robyn, Maurin, Olivier, Zuntini, Alexandre, Arias, Tatiana, Serna-Sánchez, Alejandra, Gravendeel, Barbara, Torres Jimenez, Maria Fernanda, Nargar, Katharina, Chomicki, Guillaume, Chase, Mark W, Leitch, Ilia J, Forest, Félix, Baker, William J (2021): Hundreds of nuclear and plastid loci yield novel insights into orchid relationships. American journal of botany 108 (7): 1166-1180, DOI: http://doi.org/10.5281/zenodo.7778176

OrchidaceaeCharacter evolutionNuclear genemultilocus phylogenetic treesbiologyPhylogenetic treenuclearplastid discordancefungifood and beveragesAngiosperms353Plant ScienceBiodiversitybiology.organism_classificationGenomeDNA sequencingrecombinationNuclear- plastid discordanceincongruenceEvolutionary biologyGeneticsSupermatrixPlastidOrchidaceaeEcology Evolution Behavior and SystematicsTaxonomy
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Sperm p53 concentration: a potential new biomarker for environmental pollution. Preliminary data.(EcoFoodFertility Project)

2019

Study question:We evaluated the p53 protein concentration in spermcells to test whether environmental pollution can affect expression levels of this protein. Summary answer:We found a significant difference in p53 levels between two homogeneous groups by age and lifestyle, residents in two areas with different environmental impact. What is known already:TheWorld HealthOrganization (WHO) has placed among its priority objectives the understanding of the relationships between the sources of pollution and the effects on human health, which they represent a cause of surprisingly high mortality and morbidity. International scientific literature shows that strong environmental impact may jeopardiz…

P53Settore BIO/13 - Biologia Applicatabiomarker.Settore BIO/06 - Anatomia Comparata E CitologiaSperm
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Valor de los estudios cromosómicos en espermatozoides mediante la técnica de hibridación in situ fluorescente (FISH) en parejas estériles

2013

Los varones estériles presentan una frecuencia elevada de anomalías citogenéticas, algunas de ellas detectables mediante el cariotipo, pero otras limitadas a las células germinales como resultado de meiosis anormales. Con las nuevas técnicas de reproducción asistida como la Inyección Intracitoplásmica de Espermatozoides (ICSI), la fecundación por espermatozoides cromosómicamente anormales puede dar lugar a fallos de implantación, abortos de repetición y a la transmisión de anomalías cromosómicas a la descendencia. La hibridación in situ fluorescente (FISH) de espermatozoides es una técnica de análisis citogenético que, mediante el marcado de los cromosomas con moléculas de ADN fluorescentes…

PGDdiploidíaUNESCO::CIENCIAS MÉDICAS::Ciencias clínicas::Genética clínicaUNESCO::CIENCIAS DE LA VIDA::Biología humana::Genética humanaICSIFIVembrionesEspermatozoidesFISHaneuploidíaanomalías cromosómicas:CIENCIAS DE LA VIDA::Biología humana::Genética humana [UNESCO]:CIENCIAS MÉDICAS::Ciencias clínicas::Genética clínica [UNESCO]
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Traditional Chinese Medicine Remedy to Jury: The Pharmacological Basis for the Use of Shikonin as an Anticancer Therapy

2013

Shikonin is the major constituent of the root of Lithospermum erythrorhizon, which has been used in traditional Chinese medicine to treat external wounds, burns, or dermatitis for centuries. Nowadays, this root is commonly used as an herbal medicine against cancer. Studies carried out over the past 30 years have demonstrated that many of the effects historically associated with the use of this root have a scientific basis, with shikonin and its derivatives being responsible for its pharmacological properties. These include both anti-inflammatory and anticancer effects. While previous summaries have focused on the pharmacokinetics and toxicity of shikonin, the aim of this review is to report…

PharmacologyAntitumor activitybiologyTraditional medicinebusiness.industryOrganic ChemistryAnti-Inflammatory AgentsAntineoplastic AgentsTraditional Chinese medicineLithospermum erythrorhizonbiology.organism_classificationPlant RootsBiochemistryNeoplasmsChinese traditionalDrug DiscoveryHumansMolecular MedicineMedicineMedicine Chinese TraditionalbusinessNaphthoquinonesCurrent Medicinal Chemistry
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Inherited semisterility for control of harmful insects. II. Degree of sterility and types of translocations in the mosquito Culex pipiens L.

1971

Fur die Anwendung von Semisterilitat infolge von Translokationen zur Bekampfung schadlicher Insekten ist der Grad der Semisterilitat und die Art der zugrundeliegenden Translokation von Bedeutung. Von den bisher untersuchten 124 Translokationen hatten 101 einen Sterilitatsgrad zwischen 10 und 50%, 23 uber 50 bis zu 85%. Mit dem mannlichen Geschlechtsfaktor M gekoppelte Translokationen sind zur Zeit die fur die Praxis am nutzlichsten. Sie treten nicht so haufig auf als erwartet, machen aber doch rund 1/4 aller getesteten Translokationen aus. Es werden Grunde angefuhrt, weshalb M-gekoppelte Translokationen nutzlicher sind.

PharmacologyChromosome AberrationsMaleHeterozygoteSterilityHomozygoteSterilization ReproductiveChromosomal translocationCell BiologyBiologybiology.organism_classificationMolecular biologyInsect ControlSpermatozoaCellular and Molecular NeuroscienceCulexCulex pipiensMolecular MedicineRadiation GeneticsMolecular BiologyExperientia
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