Search results for "statistical significance"

showing 10 items of 224 documents

Effects of treatments for drooling on caries risk in children and adolescents with cerebral palsy

2019

Background Neuromuscular impairment makes individuals with cerebral palsy (CP) more prone to drooling. Among the treatment options, there are procedures that interfere with saliva production. It is imperative to evaluate the effect of the different modalities since the reduction in salivary flow rate/production may exacerbate the risk of dental caries. Material and Methods The aim of this study was to compare the effects of different treatments for drooling on caries risk and salivary parameters in children and adolescents with CP. Study design A total of 142 children and adolescents with CP, aged 6 to 18 years, were assigned to groups based on the different treatments they had received for…

MaleSalivaBotulinum ToxinsAdolescentDentistryDental CariesOral Hygiene IndexDroolingCholinergic AntagonistsSalivary GlandsCerebral palsy03 medical and health sciencessymbols.namesake0302 clinical medicineStatistical significancemedicinePrevalenceHumansPoisson regressionChildSalivaGeneral Dentistrybusiness.industryDMF IndexResearchCerebral PalsyOsmolar Concentration030206 dentistrySialorrheamedicine.disease:CIENCIAS MÉDICAS [UNESCO]Medically compromised patients in DentistryOral HygieneConfidence intervalCross-Sectional StudiesOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASsymbolsRegression AnalysisSurgeryFemaleAnalysis of variancemedicine.symptombusinessBrazilMedicina Oral, Patología Oral y Cirugía Bucal
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A controlled study comparing salivary osmolality, caries experience and caries risk in patients with cerebral palsy

2018

Background Cerebral palsy (CP) is a permanent neurological disorder accompanied by secondary musculoskeletal masticatory disorder, with repercussion on chewing and deglutition functions. In these conditions, the liquids ingestion is compromised resulting in salivary osmolality alteration. The objective of this study was to compare salivary osmolality, caries experience and caries risk between normoreactive individuals and patients with CP. Material and Methods The participants were 4-20 years old: 52 patients with CP treated at a reference rehabilitation centre (study group, SG), and 52 normoreactive individuals (control group, CG). Saliva was collected for five minutes using cotton rolls. …

MaleSalivaPediatricsmedicine.medical_specialtyAdolescentNeurological disorderDental CariesGastroenterologyRisk AssessmentCerebral palsy03 medical and health sciencesYoung Adult0302 clinical medicineSwallowingStatistical significanceInternal medicineSpasticmedicineHumansIn patientChildSalivaGeneral DentistryReceiver operating characteristicbusiness.industryResearchCerebral PalsyOsmolar Concentration030206 dentistry:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseMedically compromised patients in DentistryMasticatory forceOtorhinolaryngology030220 oncology & carcinogenesisChild PreschoolUNESCO::CIENCIAS MÉDICASSurgeryFemaleCaries experiencebusinessMedicina Oral, Patología Oral y Cirugía Bucal
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Effect of orthodontic treatment on saliva, plaque and the levels of Streptococcus mutans and Lactobacillus

2009

Objectives: The aim of this study was to identify changes in the oral environment with clinical, salivary and bacterial risk markers after placement of fixed orthodontic appliances on permanent dentition. Material and Methods: With ethical approval, we used different techniques to analyzed clinical, salivary and bacterial risk markers in 34 patients (mean age, 16.7 ± 5.2 years), 14 males and 20 females; before starting orthodontic treatment and 1 month after. Clinical risk markers (decayed, missing, and filled surfaces [DMFS], O?Leary´s plaque index, and plaque pH); salivary markers (unstimulated and stimulated saliva flow rate, buffer capacity, pH, and occult blood in saliva) and bacterial…

MaleSalivaPlaque indexAdolescentPlaque phDental PlaqueDentistryStreptococcus mutansOrthodontic AppliancesLactobacillusStatistical significanceHumansMedicineGingival inflammationSalivaGeneral Dentistrybiologybusiness.industry:CIENCIAS MÉDICAS [UNESCO]Caries activitybiology.organism_classificationStreptococcus mutansLactobacillusOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASFemaleSurgerybusinessMedicina Oral Patología Oral y Cirugia Bucal
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Sex estimation by tooth dimension in a contemporary Spanish population.

2020

Aim: Sex determination is a fundamental step in the biologic profile reconstruction of unknown individuals. Teeth are frequently recovered intact, even in case of natural or mass disasters, fires, crashes or accidents. Therefore, they are very valuable in sex determination in a forensic and anthropological context. The objective of this study is to identify a method for sex determination using the mesio-distal widths of permanent teeth, in a contemporary Spanish sample. Method: The mesio-distal dimensions of permanent teeth were obtained from study casts derived from patients seeking treatment at the orthodontic clinic of the Universidad Europea de Valencia. A total of 210 patients were inc…

MaleSex Determination AnalysisAdolescentPopulationOdontologíaContext (language use)SexoLogistic regressionPathology and Forensic MedicineStatistical significanceStatisticsMedicineHumanseducationOdontometríaPermanent teethAntropologíaeducation.field_of_studyPrincipal Component AnalysisDentitionbusiness.industryMedicina forenseModels DentalDentition PermanentLogistic ModelsSpainPrincipal component analysisInclusion and exclusion criteriaFemalebusinessLawToothForensic DentistryForensic science international
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A case control study of statin and magnesium administration in patients after aneurysmal subarachnoid hemorrhage: incidence of delayed cerebral ische…

2008

To analyse the effect of the implementation of statin and magnesium treatment on delayed cerebral ischemia (DCI) and 14 day mortality in patients with subarachnoid hemorrhage (SAH).Retrospective, single-center, observational case control study. One hundred SAH patients received either simvastatin and magnesium, solely statin or no treatment.Eighteen percent (n=5) of patients receiving statin and magnesium treatment developed a DCI whereas 24% (n=5) in the statin group and 16% (n=8) in the control group had DCI. Dead by day 14 was registered in 18% (n=5) of patients in the statin and magnesium group, in 10% (n=2) in the statin group and in 27% (n=14) in the control group. None of the results…

MaleSimvastatinStatinSubarachnoid hemorrhagemedicine.drug_classIschemia610 Medicine & healthBrain Ischemia10180 Clinic for NeurosurgeryStatistical significancemedicineHumansMagnesiumcardiovascular diseasesRetrospective Studiesbusiness.industryIncidence (epidemiology)Anticholesteremic AgentsCase-control studynutritional and metabolic diseasesGeneral MedicineMiddle AgedSubarachnoid Hemorrhagemedicine.diseaseSurvival RateTreatment Outcome2728 Neurology (clinical)NeurologySimvastatinAnesthesiaCase-Control Studies2808 Neurologylipids (amino acids peptides and proteins)Observational studyFemaleNeurology (clinical)businessmedicine.drug
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Lung function after acute and repeated exposures to extremely cold air (-110 degrees C) during whole-body cryotherapy.

2006

Whole-body cryotherapy (WBC) is one mode of cold therapy, during which rheumatic patients are exposed to very cold air (-110 degrees C) in minimal clothing. It is also proposed to have a bronchodilatory effect. The aim was to examine the effects of WBC on lung function in healthy humans after acute and repeated exposures. Twenty-five healthy, non-smoking subjects participated in the study. They were exposed to WBC for 2 min three times per week for 12 weeks. The peak expiratory flow rate (PEF) and forced expiratory volume in 1 s (FEV1) were measured before and after (at 2 and 30 min) the first WBC, and then similarly at 4, 8 and 12 weeks. At all time points, after 30 min of the WBC the PEF …

MaleTime FactorsPhysiologymedicine.medical_treatmentBronchoconstrictionCryotherapyPeak Expiratory Flow RateCold Therapyhemic and lymphatic diseasesPhysiology (medical)Statistical significanceForced Expiratory VolumemedicineHumansLung functionbusiness.industryWhole body cryotherapyCold airGeneral MedicineMiddle AgedRespiratory Function TestsBronchodilatationCryotherapyAnesthesiaRespiratory Physiological PhenomenaBronchoconstrictionFemalemedicine.symptombusinesscirculatory and respiratory physiologyClinical physiology and functional imaging
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Multicenter Multireader Evaluation of an Artificial Intelligence-Based Attention Mapping System for the Detection of Prostate Cancer With Multiparame…

2020

OBJECTIVE. The purpose of this study was to evaluate in a multicenter dataset the performance of an artificial intelligence (AI) detection system with attention mapping compared with multiparametric MRI (mpMRI) interpretation in the detection of prostate cancer. MATERIALS AND METHODS. MRI examinations from five institutions were included in this study and were evaluated by nine readers. In the first round, readers evaluated mpMRI studies using the Prostate Imaging Reporting and Data System version 2. After 4 weeks, images were again presented to readers along with the AI-based detection system output. Readers accepted or rejected lesions within four AI-generated attention map boxes. Additio…

MaleUrologyAdenocarcinomaSensitivity and SpecificityArticle030218 nuclear medicine & medical imaging03 medical and health sciencesProstate cancerRandom Allocation0302 clinical medicineLaparoscopicProstateArtificial IntelligenceStatistical significanceMedicineHumansAttentionRadiology Nuclear Medicine and imagingDiagnosis Computer-AssistedMultiparametric Magnetic Resonance ImagingAgedRetrospective StudiesObserver VariationProstate cancerbusiness.industryartificial intelligence; laparoscopic; MRI; multiparametric; prostate cancer; radical prostatectomy; robot-assistedSignificant differenceCancerMultiparametric MRIProstatic NeoplasmsGeneral MedicineRobot-assistedMiddle Agedmedicine.diseaseRadical prostatectomymedicine.anatomical_structure030220 oncology & carcinogenesisMapping systemMultiparametricArtificial intelligencebusinessAlgorithmsMriAJR. American journal of roentgenology
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Direct costs of glaucoma and severity of the disease: a multinational long term study of resource utilisation in Europe

2005

International audience; Background: Resource utilisation and direct costs associated with glaucoma progression in Europe are unknown. As population progressively ages, the economic impact of the disease will increase. Methods: From a total of 1655 consecutive cases, the records of 194 patients were selected and stratified by disease severity. Record selection was based on diagnoses of primary open angle glaucoma, glaucoma suspect, ocular hypertension, or normal tension glaucoma; 5 years minimum follow up were required. Glaucoma severity was assessed using a six stage glaucoma staging system based on static threshold visual field parameters. Resource utilisation data were abstracted from the…

Maleage distributionOrganes des sensgenetic structuresOffice VisitsOcular hypertensionGlaucomaDiseaseintraocular hypertensionSeverity of Illness IndexIndirect costs0302 clinical medicineambulatory careNormal tension glaucomamiddle agedopen angle glaucoma80 and overMedicine030212 general & internal medicinepathophysiologystatistical significanceAged 80 and overeducation.field_of_studyadultdisease coursearticlehealth care costclinical trialHealth Care Costshealth care planningSensory Systems3. Good healthEuropeagedfemalepriority journalstatisticsHealth Resourcesdisease severityadult; aged; article; disease course; disease severity; Europe; female; follow up; general practitioner; glaucoma; health care cost; health care utilization; human; intraocular hypertension; major clinical study; male; medical record; open angle glaucoma; priority journal; statistical significance; visual field; age distribution; ambulatory care; clinical trial; drug cost; economics; health care planning; hospitalization; middle aged; multicenter study; pathophysiology; sex ratio; statistics; utilization review; Adult; Age Distribution; Aged; Aged 80 and over; Drug Costs; Europe; Female; Follow-Up Studies; Glaucoma; Health Care Costs; Health Resources; Humans; Male; Middle Aged; Office Visits; Severity of Illness Index; Sex Distribution; Visual Fieldshospitalizationvisual fieldWorld Viewsmedicine.medical_specialtyOpen angle glaucomadrug costPopulationSensory OrgansMédecine humaine et pathologiemedical recordDrug Costs03 medical and health sciencesCellular and Molecular Neurosciencehealth care utilizationSeverity of illnessfollow upHumanshumanSex Distribution[SDV.MHEP.OS]Life Sciences [q-bio]/Human health and pathology/Sensory Organseducationutilization reviewSettore MED/30 - Malattie Apparato Visivobusiness.industryGlaucomaeconomicssex ratiomedicine.diseasemajor clinical studyeye diseasesOphthalmologymulticenter studygeneral practitionerEmergency medicine030221 ophthalmology & optometryOptometryHuman health and pathologyVisual Fieldsbusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyFollow-Up Studies
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The effect of high-volume online haemodiafiltration on nutritional status and body composition: the ProtEin Stores prEservaTion (PESET) study

2018

Background Compared with conventional haemodialysis (HD), online haemodiafiltration (OL-HDF) achieves a more efficient removal of uraemic toxins and reduces inflammation, which could favourably affect nutritional status. We evaluate the effect of OL-HDF on body composition and nutritional status in prevalent high-flux HD (HF-HD) patients. Methods In all, 33 adults with chronic kidney disease (CKD) Stage 5 undergoing maintenance HF-HD were assigned to post-dilution OL-HDF (n = 17) or to remain on HF-HD (n = 16, control group) for 12 months. The primary outcome was the change in lean tissue mass (LTM), intracellular water (ICW) and body cell mass (BCM) assessed by multifrequency bioimpedance …

Maledialysis patientsNon-Randomized Controlled Trials as Topicmuscleconvective therapies[SDV]Life Sciences [q-bio]medicine.medical_treatment030232 urology & nephrology030204 cardiovascular system & hematologyBody compositionGastroenterology0302 clinical medicineEstadística e Investigación Operativanocturnal homeMedicineProspective StudiesProspective cohort studyWasting2. Zero hungerhemodialysishigh-flux hemodialysisMiddle AgedUrology & Nephrology3. Good healthhaemodialysisHaemodialysisnutritionHaemodiafiltrationNephrologyall-cause mortalityFemaleHemodialysischronic kidney-diseasemedicine.symptomProtein-energy wastingspectroscopymedicine.medical_specialtyNutritional StatusHemodiafiltrationhaemodiafiltrationsurvivalCachexia03 medical and health sciencesRenal DialysisStatistical significanceInternal medicinebioimpedanceHumansDialysisNutritionInflammationbody compositionTransplantationbusiness.industrymedicine.diseaseConfidence intervalCase-Control StudiesKidney Failure Chronicmassprotein-energy wastingbusinessconventional hemodialysisHospitals High-VolumeKidney diseaseNephrology Dialysis Transplantation
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Anterior Segment Biometry and Their Correlation with Corneal Biomechanics in Caucasian Children.

2018

Purpose: To assess the relationship between the corneal biomechanical parameters and the anterior segment parameters in Caucasian children. Methods: This study included 293 eyes from 293 healthy children aged between 6 and 17 years. Corneal hysteresis (CH) and corneal resistance factor (CRF) were evaluated with the Ocular Response Analyzer, axial length (AL) with IOLMaster and the anterior segment with Pentacam. Anterior segment parameters obtained were the following: central corneal thickness (CCT), corneal volume (CV), anterior chamber depth (ACD), anterior chamber volume (ACV) and mean anterior and posterior keratometry. Two multiple linear regression models were constructed to assess th…

Malemedicine.medical_specialtyBiometrygenetic structuresAdolescentanterior ocular segmentWhite Peoplelaw.inventionCorneal hysteresisCorrelationCorneaCorneal biomechanics03 medical and health sciencesCellular and Molecular Neuroscience0302 clinical medicinechildrenlawAnterior Eye SegmentReference ValuesStatistical significanceOphthalmologyLinear regressionMedicineHumansChildIntraocular PressureKeratometerbusiness.industryBiomechanicsCorneal TopographyAxial lengtheye diseasesSensory SystemsElasticityOphthalmologyCross-Sectional Studies030221 ophthalmology & optometryFemalesense organsocular response analyzerbusiness030217 neurology & neurosurgeryCurrent eye research
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