Search results for "status"

The influence of medication on the course of major depression: a 3-year-follow-up with polydiagnostic measures.

1988

Liebowitz Social Anxiety Scale (LSAS): Optimal cut points for remission and response in a German sample

2017

The Liebowitz Social Anxiety Scale (LSAS) is the most frequently used instrument to assess social anxiety disorder (SAD) in clinical research and practice. Both a self-reported (LSAS-SR) and a clinician-administered (LSAS-CA) version are available. The aim of the present study was to define optimal cut-off (OC) scores for remission and response to treatment for the LSAS in a German sample. Data of N = 311 patients with SAD were used who had completed psychotherapeutic treatment within a multicentre randomized controlled trial. Diagnosis of SAD and reduction in symptom severity according to the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, 4th editi…

Psychometric properties of the General Self Efficacy-12 Scale in Spanish: general and clinical population samples.

2014

The General Self Efficacy Scale (GSES-12) is a short version of the Sherer’s Self-Efficacy Scale, and evaluates a general dimension and three aspects of self-efficacy: initiative, persistence and effort. The aim of this study is to explore the factorial structure, reliability, and criterion validity of the Spanish adaptation of the GSES-12 in general and clinical populations. The sample was composed of 714 volunteers (332 from the clinical population). Results of the principal components analysis yielded a 3-factor structure that was later confirmed through Confirmatory Factor Analysis. Moreover, this study shows good internal consistency and testretest values, and differences in self-effic…

Validation of the Italian version of the Burn Specific Health Scale-Brief

2014

Introduction A growing awareness of psychological and functional impairment due to burns have led to the development of specific instruments to evaluate Quality of Life in this population, such as the Burn Specific Health Scale - Brief (BSHS-B), whose psychometric properties have been consistently verified. The aim of this study was to translate the BSHS-B into Italian and to investigate its reliability and validity. Methods Translation procedures were carried out according to accepted standards. Internal reliability was assessed using Cronbach's alpha coefficient. Concurrent validity was evaluated through correlations between the BSHS-B and the Short-Form 36 Health Survey (SF-36), the Self…

Development of a new measure for assessing insight: Psychometric properties of the insight orientation scale (IOS)

2015

Abstract Introduction Given the centrality of insight in promoting change, the relevance of measures for assessing this construct has become increasingly clear. This paper describes a new self-report measure for assessing some of the characteristics of insight, the insight orientation scale (IOS). Aims In study 1, we evaluated the factor structure and the reliability of the scale. In study 2, we analyzed the concurrent and discriminant validity of the scale in patients with different clinical diagnoses. Methods In study 1 participants were 600 individuals (41.1% male, 58.9% female) with a mean age of 33.95 years (SD = 13.04). In study 2 participants were 136 individuals divided into the fol…

The effect of lifelong exercise on psychomotor reaction time: a study of 38 pairs of male monozygotic twins

1998

Purpose: The aim was to study the effect of lifetime physical activity on psychomotor speed. Methods: Foot and dominant hand visual simple and choice psychomotor reaction times were studied among monozygotic twins (38 pairs) aged 35-69, discordant for lifetime exercise histories. Results: There was a trend that some components of psychomotor reaction time were faster for frequent than for occasional exercisers. but the findings were not consistent for the hand and feet. After controlling for occupational physical activity, only choice decision time for the hand (26 ms, P < 0.01) and choice reaction time for the contralateral foot (51 ms, P < 0.05) both remained 7% faster. There was no trend…

Straight gyrus morphology in first-episode schizophrenia-spectrum patients

2010

et al.

Predictors of neurocognitive impairment at 3years after a first episode non-affective psychosis

2013

Abstract Background Neurocognitive impairment is a core component of schizophrenia. However, patients show great variability in the level and course of deficits. The goal of the present longitudinal study was to identify predictors of neurocognitive impairment in first episode psychosis patients. Methods N eurocognitive performance was analyzed in a cohort of 146 patients 3 years after a first episode non-affective psychosis. Subgroups, impaired vs. unimpaired, were compared on baseline clinical, neuropsychological, premorbid and sociodemographic characteristics. Results Fifty-nine percent of participants presented general neurocognitive impairment and regression analyses demonstrated that …

Nonlinear EEG dynamics during sleep in depression and schizophrenia.

1994

The article deals with the question, whether nonlinear analysis of the sleep EEG may give clues to understanding of disturbed information processing in psychiatric diseases. We point out how the nonlinear approach to EEG dynamics is motivated and review recent investigations concerning nonlinear dynamical properties of physiological systems. We present calculations of the correlation dimension D2 and the principal Lyapunov-exponent lambda 1 for sleep EEG data from 9 depressive and 11 schizophrenic inpatients compared to healthy controls. Combining the findings for D2 and lambda 1 our results point to altered nonlinear brain dynamics mainly during slow wave sleep in depression and during REM…

Savoxepine: invalidation of an "atypical" neuroleptic response pattern predicted by animal models in an open clinical trial with schizophrenic patien…

1991

The new tetracyclic compound savoxepine exhibits potent antidopaminergic effects with preferential activity in the hippocampus as compared to striatum in rat brain. As a result of behavioural animal models and regional differences in dopamine receptor binding characteristics, it has been suggested to possess an "atypical" neuroleptic response pattern. In an open clinical trial, savoxepine was administered to 12 in-patients suffering from paranoid schizophrenia and schizophreniform disorder (DSM-III). Eight patients were treated with a stable dose of 0.5 mg per day throughout the study, while in the remaining patients higher doses up to 20 mg/day were administered. Mean total BPRS scores and…