Search results for "technique"

showing 10 items of 5596 documents

Tumor targeting of baculovirus displaying a lymphatic homing peptide.

2008

Background Tumor-associated cells and vasculature express attractive molecular markers for site-specific vector targeting. To attain tumor-selective tropism, we recently developed a baculovirus vector displaying the lymphatic homing peptide LyP-1, originally identified by ex vivo/in vivo screening of phage display libraries, on the viral envelope by fusion to the transmembrane anchor of vesicular stomatitis virus G-protein. Methods In the present study, we explored the specificity and kinetics of viral binding and internalization as well as in vivo tumor homing of the LyP-1 displaying virus to elucidate the applicability of baculovirus for targeted therapies. Results We demonstrated that th…

virusesmedia_common.quotation_subjectGenetic VectorsMice NudeBiologyPeptides CyclicVirus03 medical and health sciencesTransduction (genetics)Mice0302 clinical medicineViral envelopeViral Envelope ProteinsIn vivoTransduction GeneticCell Line TumorNeoplasmsDrug DiscoveryGeneticsAnimalsHumansTransgenesInternalizationMolecular BiologyGenetics (clinical)030304 developmental biologymedia_commonLymphatic Vessels0303 health sciencesBinding SitesMembrane GlycoproteinsGene Transfer TechniquesGenetic Therapybiology.organism_classificationMolecular biology3. Good healthCell biologyVesicular stomatitis virus030220 oncology & carcinogenesisMolecular MedicineBaculoviridaeEx vivoHoming (hematopoietic)The journal of gene medicine
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The ALICE experiment at the CERN LHC

2008

Journal of Instrumentation 3(08), S08002 (2008). doi:10.1088/1748-0221/3/08/S08002

visible and IR photonsLiquid detectorshigh energyPhotonPhysics::Instrumentation and DetectorsTransition radiation detectorsTiming detectors01 natural sciencesOverall mechanics designParticle identificationSoftware architecturesParticle identification methodsGaseous detectorscluster findingDetector cooling and thermo-stabilizationDetector groundingParticle tracking detectors[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Special cablesDetector alignment and calibration methodsDetectors and Experimental TechniquesNuclear ExperimentVoltage distributions.Photon detectors for UVInstrumentationMathematical PhysicsQuantum chromodynamicsPhysicsLarge Hadron ColliderSpectrometersPhysicsDetectorcalibration and fitting methodsTransition radiation detectorScintillatorsData processing methodsAnalysis and statistical methodsData reduction methodsParticle physicsCherenkov and transition radiationTime projection chambers610dE/dx detectorsNuclear physicsCalorimetersPattern recognitionGamma detectors0103 physical sciencesddc:610Solid state detectors010306 general physicsMuonInstrumentation for heavy-ion acceleratorsSpectrometerLarge detector systems for particle and astroparticle physics010308 nuclear & particles physicsCERN; LHC; ALICE; heavy ion; QGPCherenkov detectorsComputingVoltage distributionsManufacturingscintillation and light emission processesanalysis and statistical methods; calorimeters; cherenkov and transition radiation; cherenkov detectors; computing; data processing methods; data reduction methods; de/dx detectors; detector alignment and calibration methods; detector cooling and thermo-stabilization; detector design and construction technologies and materials; detector grounding; gamma detectors; gaseous detectors; instrumentation for heavy-ion accelerators; instrumentation for particle accelerators and storage rings - high energy; large detector systems for particle and astroparticle physics; liquid detectors; manufacturing; overall mechanics design; particle identification methods; particle tracking detectors; pattern recognition; cluster finding; calibration and fitting methods; photon detectors for uv; visible and ir photons; scintillators; scintillation and light emission processes; simulation methods and programs; software architectures; solid state detectors; special cables; spectrometers; time projection chambers; timing detectors; transition radiation detectors; voltage distributionsInstrumentation for particle accelerators and storage ringsInstrumentation; Mathematical PhysicsHigh Energy Physics::ExperimentSimulation methods and programsDetector design and construction technologies and materials
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Procedures for study of teaching practices. Literature Review

2012

Interest in studying teaching practices has increased, because of the need to evaluate teachers and dissatisfaction with the usual ways of doing it. Recent approaches with Value-Added Models, based on students’ results on achievement tests do not seem satisfactory. The article is based on a review of literature and classifies the approaches to practices in three groups: instruments based on information given by teachers; observation protocols; and approaches based on the analysis of products of the practices. Specific tools are described and advantages and disadvantages of the three approaches are discussed. El interés por las prácticas docentes ha aumentado, en parte por la necesidad de ev…

viñetasEducaciónClassroom ResearchInstructional Effectivenesslcsh:LB5-3640evaluación de maestrosVignettesGrupo BClassroom Observation TechniquesPortfolios (Background Materials)UNESCO::PEDAGOGÍAencuestas de maestrosrecolección de datosTeacher Surveysefectividad instruccionalData Collectiontécnicas de observación en aulaEfectividad docenteinvestigación en aulaAlternative AssessmentResearch Toolsevaluación alternativalcsh:Theory and practice of educationTeacher EffectivenessportafoliosPsicología y educación:PEDAGOGÍA [UNESCO]Teacher Evaluationinstrumentos de investigación
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Vārdu krājumu novērtējums ar dažādu testēšanu paņēmienu izmantošanu

2016

Darbā tika pētītas vārdu krājuma testēšanas paņēmienu priekšrocības un trūkumi un visefektīvākais un drošākais paņēmiens vārdu krājuma pārbaudei mācību apstākļos. Pētījuma rezultāti spēj veicināt izvēli par labu konkrētam testēšanas paņēmienam, saskaņā ar novērtēšanas veidu un mērķi, tēmu, mērķauditoriju un vidi. Darba teorētiskā daļa ir balstīta uz Arthur Hughes (2003), Scott Thornbury (2002), John Read (2000) un Penny Ur (1999) teorijas. Gadījuma metodes ietvaros tika vadīta mācību nodarbība, pēc kuras studentu zināšanas tika novērtētas ar autores izstrādāto testa palīdzību. Kvantitatīva analīze tika pielietota testa rezultātu noteikšanā un uzticamības mērīšanā, turklāt kvalitatīva analīz…

vocabulary assessmentValodniecībamatchingadvantages and drawbackstesting techniquesvocabulary
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Study of vocalists' use of emotions in performance preparation

2015

Musicians and educators understand the importance of expressivity in vocal performance. Despite the acceptance of expressivity as a crucial element in musical performance, educators have reported addressing it only cursorily or not addressing it at all when preparing for a performance. For these reasons, this research has focused on techniques used by trained musicians when preparing a performance, to be adapted and applied for use by teachers with their large vocal ensembles. Participants in this study were enrolled in vocal / operatic performance programs at universities in the United States, Ireland, Finland, and Hong Kong. Their progress was tracked throughout the semester by three ques…

vocal performancelaulajatpedagogyoppiminensingersexpressive techniquesmusiikkiemotionsexpressivityilmeikäs musiikkiesitysilmaisutunteetComputingMilieux_COMPUTERSANDEDUCATIONesityksetGERMS Model
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Highly sensitive olfactory biosensors for the detection of volatile organic compounds by surface plasmon resonance imaging

2018

International audience; Nowadays, monitoring of volatile organic compounds (VOCs) is very important in various domains. In this work, we aimed to develop sensitive olfactory biosensors using odorant binding proteins (OBPs) as sensing materials. Three rat OBP3 derivatives with customized binding properties were designed and immobilized on the same chip for the detection of VOCs in solution by surface plasmon resonance imaging (SPRi). We demonstrated that the proteins kept their binding properties after the immobilization under optimized conditions. The obtained olfactory biosensors exhibited very low limits of detection in both concentration (200pM of beta-ionone) and in molecular weight of …

volatile organic compoundConformational change[SDV.BIO]Life Sciences [q-bio]/BiotechnologyOdorant bindingBiomedical EngineeringBiophysicsBiosensing Techniques02 engineering and technologyReceptors Odorant01 natural sciencesHexanal[SPI]Engineering Sciences [physics]chemistry.chemical_compoundElectrochemistryAnimalsVolatile organic compoundComputingMilieux_MISCELLANEOUSDetection limitchemistry.chemical_classificationVolatile Organic CompoundsChromatographyChemistry010401 analytical chemistryGeneral MedicineRepeatabilitySurface Plasmon Resonance021001 nanoscience & nanotechnologyRats0104 chemical sciencesSmellsurface plasmon resonance imagingofactory biosensor0210 nano-technologySelectivityBiosensorodorant binding proteinsBiotechnologyBiosensors and Bioelectronics
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Spatially resolved SO2 flux emissions from Mt Etna

2016

Abstract We report on a systematic record of SO2 flux emissions from individual vents of Etna volcano (Sicily), which we obtained using a permanent UV camera network. Observations were carried out in summer 2014, a period encompassing two eruptive episodes of the New South East Crater (NSEC) and a fissure‐fed eruption in the upper Valle del Bove. We demonstrate that our vent‐resolved SO2 flux time series allow capturing shifts in activity from one vent to another and contribute to our understanding of Etna's shallow plumbing system structure. We find that the fissure eruption contributed ~50,000 t of SO2 or ~30% of the SO2 emitted by the volcano during the 5 July to 10 August eruptive inter…

volcanic gaseGeologicalRemote Sensing and DisastersVolcanologyVolcano SeismologyVolcano MonitoringResearch LettersVolcanic GasesVolcanic Hazards and Risksvolcanic SO2 fluxSO2 camerasResearch LetterEtnaRemote Sensing of VolcanoesInstruments and TechniquesDisaster Risk Analysis and AssessmentSO2 cameraGeophysicEarth and Planetary Sciences (all)volcanic degassingNatural HazardsSeismologySolid EarthGeophysical Research Letters
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Experimental Validation of Maximum Constant Boost Control and Switching Frequency Optimal for three-phase Quasi-Z-Source Converters

2020

This paper presents a modified modulation scheme for quasi-Z-Source converters, based on the Maximum Constant Boost Control (MCBC) concept and Switching Frequency Optimal (SFO) as reference signal. The effectiveness of the proposed technique is validated by comparing the obtained results (in terms of AC harmonic content and voltage stress) with those carried out from traditional modulation schemes. For this reason, a test bench has been assembled and the benefits of the SFO MCBC modulation scheme have been valuated.

voltage stressTest benchQuasi-Z-source InverterSettore ING-IND/32 - Convertitori Macchine E Azionamenti ElettriciConvertersSignalSettore ING-IND/31 - ElettrotecnicaharmonicThree-phaseModulationControl theorymodulation techniqueHarmonicsHarmonicharmonics modulation techniques Quasi-Z-source Inverter voltage stressMathematicsVoltage2020 2nd IEEE International Conference on Industrial Electronics for Sustainable Energy Systems (IESES)
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Gestions de l'eau et du développement urbain dans l'espace dijonnais :quels modes d'intégration territoriale ?

2006

Urban growth, jointed to technical networks, contributes to human pressure on water resources. In the meantime, the water French policy put management of urban development in accordance with catchments and hydrologic dynamics; that makes districts and intermunicipal groupings adopt new areas and action systems. The urban area of Dijon is located in three catchments and above a wide groundwater. This case shows urban water management gives greater place to precariousness and common character of water resources, even if institutional responses mainly concern town planning regulation.

water management.[SHS.GEO] Humanities and Social Sciences/Geographyintermunicipal grouping[SHS.GEO]Humanities and Social Sciences/Geographyhydrologic areasdéveloppement urbainterritoires hydrologiquestechnical networks[ SHS.GEO ] Humanities and Social Sciences/Geographyréseaux techniquesurban growthwater managementintercommunalitégestion de l'eaugestion de l'eau.
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Development of an immunochromatographic assay based on carbon nanoparticles for the determination of the phytoregulator forchlorfenuron

2013

Rapid analytical methods enabling the determination of diverse targets are essential in a number of research areas, from clinical diagnostics to feed and food quality and safety. Herein, the development of a quantitative immunochromatographic assay for the detection of the synthetic phytoregulator forchlorfenuron (CPPU) is described. The competitive lateral flow immunoassay (LFIA) was based on the immobilization onto a nitrocellulose membrane of an ovalbumin-CPPU conjugate (test line) and on the use of an immunodetection ligand consisting of carbon nanoparticles labeled with an anti-CPPU monoclonal antibody through interaction with a secondary antibody. The presence of CPPU in horticultural…

water samplesCarbon nanoparticlesAnalyteImmunoreactive stripsPyridinesCarbon NanoparticlesBiomedical EngineeringBiophysicsEnzyme-Linked Immunosorbent AssayCPPUBiosensing Techniquesantibody-based immunoassayForchlorfenuronbiosensorHigh-performance liquid chromatographychemistry.chemical_compoundElectrochemistryImmunoassayDetection limitvalidationChromatographyChemistrystrip testPhenylurea Compoundslateral flow immunoassayAntibodies Monoclonalcomputer image-analysisGeneral MedicineCarbonHaptendipstick assayBBP Bioconversionrapid detectionImmunosensingNanoparticlessensitive detectionBiosensorNitrocelluloseBiotechnologyConjugate
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