Search results for "therapy."

Calidad de la farmacoterapia y seguridad de los pacientes en hemodiálisis tratados con estimulantes eritropoyéticos

2008

Objective: To assess an interdisciplinary programme for the improvement of pharmacotherapy quality and patient safety in patients with chronic renal disease who are treated with erythropoiesis-stimulating agents. Method: Observational, longitudinal study. Retrospective analysis (period A) and prospective analysis (period B) following implementation of the programme for haemoglobin values and monthly erythropoiesis- stimulating agent dosage. The proportion of patients with haemoglobin values within the target range (10-5-12.5 g/dl) and those with values above the safety limit (≥ 12.5g/dl) were compared every four months and the average percentage of time with haemoglobin values within the ta…

Prognostic factors in the treatment of Ewing's sarcoma

1987

From 1981 up to February 1985, a total of 93 protocol patients entered the study CESS 81. The protocol recommended an initial 18-week period of polychemotherapy (VACA) followed by local therapy and two additional cycles of chemotherapy. Local therapy consisted either of radical surgery or of incomplete resection plus postoperative irradiation with 36 Gy or of radiotherapy alone (46 and 60 Gy). Centrally located lesions were always irradiated with 60 Gy. This article summarizes the data after 5 years. Data of 93 patients were analysed in October 1986 after a median follow-up of 37 months. The projected 5-year survival is 50%. The relapse rate was 42%, distant relapses occurred in 19%, local …

L’échographie pulmonaire : une aide au diagnostic et au contrôle de la réponse à la kinésithérapie. À propos d’un cas

2017

Introduction L’echographie pulmonaire pourrait etre un outil interessant pour le kinesitherapeute puisqu’elle pourrait permettre d’ameliorer l’indication et le suivi du traitement par kinesitherapie respiratoire [1] . A notre connaissance, aucune etude n’a evalue l’impact de l’echographie pulmonaire sur le processus de decision clinique du kinesitherapeute. Ce rapport de cas aborde l’interet de l’echographie pulmonaire en kinesitherapie respiratoire chez une patiente avec une consolidation pulmonaire. Materiel, population et methode Ce rapport de cas est ecrit suivant les recommandations de « The CARE guideline » [2] . La patiente etait une femme de 68 ans, non intubee et hospitalisee dans …

Lebermetastasen kolorektaler Karzinome - wie oft kann man operieren?

2007

Recurrent liver metastases of colorectal carcinoma are frequent. The repeat hepatectomy is superior to other therapeutic options. In about 20 % of patients with recurrent liver metastases a complete resection (R 0) is possible. The morbidity of repeat hepatectomy is similar to that of first hepatectomy. The 5-year survival rate after repeat hepatectomy ranges between 30 and 40 %. Often in the follow-up additional operations become necessary for extrahepatic recurrencies. For determination of the optimal therapy an interdisciplinary approach must be chosen.

1.12 C-Reactive Protein is Associated with Aortic Stiffness Independently of Microalbuminuria in Essential Hypertension

2008

Health-related quality of life (HRQOL) in patients (pts) with advanced gastric cancer/gastroesophageal junction cancer (GC/GEJC) or esophageal adenoc…

2021

4066 Background: CheckMate 649 (NCT02872116) is a randomized, open label phase 3 study in first line (1L) GC/GEJC/EAC. Prespecified interim results showed statistically significant improvement in overall survival (OS) and progression-free survival (PFS) for N+C vs C in all randomized pts and pts whose tumors expressed programmed death-ligand 1 combined positive score (CPS) ≥ 5. We present interim HRQOL results for CPS ≥ 5 pts, included as exploratory in the study. Methods: HRQOL was assessed using EQ-5D-3L (EQ-5D) and Functional Assessment of Cancer Therapy–Gastric Cancer (FACT-Ga). Assessments were performed at baseline (BL), every 6 weeks during treatment, and during follow-up. Change fr…

P–435 LH preserves oocyte-granulosa cell communication in mouse ovaries exposed to chemotherapy with alkylating agents

2021

Abstract Study question Does Luteinizing Hormone (LH) protect the follicular endowment and growth by improving oocyte-granulosa cell (GC) communication of follicles exposed to chemotherapy at the primordial stage? Summary answer LH treatment protects mouse primordial follicles against alkylating agents by preventing the chemotherapy-induced follicular depletion and the impairment of oocyte-GC communication during follicular growth. What is known already Impaired folliculogenesis is one of the most common deleterious side effects of alkylating agents in ovaries. Bidirectional communication between the oocyte and surrounding GCs is crucial for oocyte development. Therefore, defective gap junc…

Students’ perceptions on three-way pedagogical models hybridization: contributing to the development of active identities

2021

The goal of the present study was to explore Primary Education students’ views on their involvement in a three pedagogical models’ hybridization (Health-Based Physical Education, Cooperative Learni...

Anwendung der sport- und bewegungsbezogenen Selbstkonkordanz auf den Leistungssport

2014

Basierend auf der Selbstdeterminationstheorie (Deci & Ryan, 2012) und dem Selbstkonkordanz-Modell (Sheldon & Elliot, 1999) haben Seelig und Fuchs (2006) eine Skala zur Messung der sport- und bewegungsbezogenen Selbstkonkordanz (SSK-Skala) konstruiert. Da die SSK-Skala bisher nur im Kontext des Breiten- und Gesundheitssports angewendet und überprüft wurde, ist das Ziel der vorliegenden Studie, das Konzept der Selbstkonkordanz auf den Leistungssport zu übertragen. Aufbauend auf der Arbeit von Seelig und Fuchs (2006) nahmen 100 leistungsorientierte Schwimmer und Schwimmerinnen an einer Online-Befragung teil. Das Ergebnis der explorativen Faktorenanalyse legt nahe, dass es für den Leis…

Use of bone scintigraphy in the early diagnosis of bisphosphonate related osteonecrosis of the jaw. Case report and review of the literature

2018

The main aim of the present report is to show the potential utility of bone scintigraphy for the diagnosis of jaw osteonecrosis. We report the history of a 62-year-old woman underwent breast cancer surgery in 2010. Moreover, patient received postoperative radiotherapy and chemotherapy. Intravenous bisphosphonates were also added to the treatment strategy to reduce the risk of bone metastasis. However, a hypermetabolic focus on left hemimandible was evidenced with a bone scintigraphy during follow up. After a careful study, the diagnosis of Bisphosphonate Related Ostneonecrosis of the Jaw (BRONJ) was carried out. This case highlights that bone scintigraphy may be extremely helpful for the ea…