Search results for "tilat"

showing 10 items of 730 documents

Comparative intention-to-treat analysis of the video-assisted thoracoscopic surgery approach to pulmonary segmentectomy for lung carcinoma

2015

Objectives To compare the video-assisted thoracoscopic surgery (VATS) with the open thoracotomy access to pulmonary segmentectomy by the clinical outcomes and long-term survival in lung carcinoma. Methods Non-randomized comparative intention-to-treat study of prospective institutional registry data and survival data of 100 consecutive patients undergoing segmentectomy. Results Within one decade (2002-12), 100 patients with proven or highly suspected lung carcinoma underwent 100 anatomical sub-lobar pulmonary resections (52 typical and 20 atypical segmentectomies, 28 split-lobe procedures). Fifty-six patients were operated by VATS and 44 by thoracotomy access. Comparison of demographic, medi…

MalePulmonary and Respiratory Medicinemedicine.medical_specialtySingle lung ventilationLung Neoplasmsmedicine.medical_treatmentPulmonary segmentectomyDisease-Free SurvivalGermanymedicineCarcinomaHumansPostoperative PeriodProspective StudiesThoracotomyPneumonectomyAgedIntention-to-treat analysisLungThoracic Surgery Video-Assistedbusiness.industryGeneral surgeryCancermedicine.diseaseIntention to Treat AnalysisSurgerySurvival Ratemedicine.anatomical_structureVideo-assisted thoracoscopic surgeryFemaleSurgeryCardiology and Cardiovascular MedicinebusinessInteractive CardioVascular and Thoracic Surgery
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Individualised perioperative open-lung approach versus standard protective ventilation in abdominal surgery (iPROVE): a randomised controlled trial

2018

Background The effects of individualised perioperative lung-protective ventilation (based on the open-lung approach [OLA]) on postoperative complications is unknown. We aimed to investigate the effects of intraoperative and postoperative ventilatory management in patients scheduled for abdominal surgery, compared with standard protective ventilation. Methods We did this prospective, multicentre, randomised controlled trial in 21 teaching hospitals in Spain. We enrolled patients who were aged 18 years or older, were scheduled to have abdominal surgery with an expected time of longer than 2 h, had intermediate-to-high-risk of developing postoperative pulmonary complications, and who had a bod…

MalePulmonary and Respiratory Medicinemedicine.medical_treatmentPopulationPerioperative Carelaw.inventionPositive-Pressure Respiration03 medical and health sciencesPostoperative Complications0302 clinical medicineRandomized controlled trial030202 anesthesiologylawOxygen therapyAbdomenmedicineHumansProspective Studies030212 general & internal medicineContinuous positive airway pressureeducationLungAgedMechanical ventilationeducation.field_of_studybusiness.industryPerioperativeMiddle AgedRespiration Artificialrespiratory tract diseasesTreatment OutcomeSpainAnesthesiaBreathingFemalebusinessAbdominal surgery
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Use of high flow nasal cannula in patients with acute respiratory failure in general wards under intensivists supervision: a single center observatio…

2022

Abstract Background Few data exist on high flow nasal cannula (HFNC) use in patients with acute respiratory failure (ARF) admitted to general wards. Rationale and objectives To retrospectively evaluate feasibility and safety of HFNC in general wards under the intensivist-supervision and after specific training. Methods Patients with ARF (dyspnea, respiratory rate-RR > 25/min, 150 < PaO2/FiO2 < 300 mmHg during oxygen therapy) admitted to nine wards of an academic hospital were included. Gas-exchange, RR, and comfort were assessed before HFNC and after 2 and 24 h of application. Results 150 patients (81 male, age 74 [60–80] years, SOFA 4 [2–4]), 123 with de-novo ARF underwent HFNC wi…

MaleRespiratory Distress SyndromeNoninvasive VentilationOxygen Inhalation TherapyARFHFNCOxygenGeneral-wardsDyspneaAHRFICU-supervisionPatients' RoomsCannulaHumansSafetyRespiratory InsufficiencyAgedRetrospective Studies
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Spontaneous Breathing in Early Acute Respiratory Distress Syndrome

2019

Supplemental Digital Content is available in the text.

MaleRespiratory ratemedicine.medical_treatmentlnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4]Clinical InvestigationsRespiration Artificial/methodsmechanical ventilationCritical Care and Intensive Care MedicineNOPositive-Pressure Respiration03 medical and health sciences0302 clinical medicineacute respiratory distress syndrome controlled mechanical ventilation spontaneous breathing supported ventilationRespiratory RatemedicineHumansProspective StudiesProspective cohort studyArtificial/methodsMechanical ventilationRespiratory Distress Syndromebusiness.industryRespirationConfounding030208 emergency & critical care medicineOdds ratioTidal Wavesacute respiratory distress syndromeMiddle AgedRespiration Artificial3. Good healthcontrolled mechanical ventilationTreatment Outcome030228 respiratory systemAnesthesiasupported ventilationBreathingComputingMethodologies_DOCUMENTANDTEXTPROCESSINGspontaneous breathingRespiratory Distress Syndrome Adult/physiopathologyObservational studyARDSFemaleAdult/physiopathologybusinessRespiratory InsufficiencyCohort studyCritical Care Medicine
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Ultra-low tidal volume ventilation-A novel and effective ventilation strategy during experimental cardiopulmonary resuscitation.

2018

Abstract Background The effects of different ventilation strategies during CPR on patient outcomes and lung physiology are still poorly understood. This study compares positive pressure ventilation (IPPV) to passive oxygenation (CPAP) and a novel ultra-low tidal volume ventilation (ULTVV) regimen in an experimental ventricular fibrillation animal model. Study design Prospective randomized controlled trial. Animals 30 male German landrace pigs (16–20 weeks). Methods Ventricular fibrillation was induced in anesthetized and instrumented pigs and the animals were randomized into three groups. Mechanical CPR was initiated and ventilation was either provided by means of standard IPPV (RR: 10/min,…

MaleResuscitationSwinemedicine.medical_treatmentRespiratory physiology030204 cardiovascular system & hematologyEmergency NursingLung injuryAdvanced Cardiac Life SupportReal-Time Polymerase Chain ReactionIntermittent Positive-Pressure Ventilation03 medical and health sciencesRandom Allocation0302 clinical medicinemedicineTidal VolumeAnimalsHumansCardiopulmonary resuscitationTidal volumeAnalysis of VarianceContinuous Positive Airway Pressurebusiness.industryPulmonary Gas Exchange030208 emergency & critical care medicineOxygenationLung Injurymedicine.diseaserespiratory tract diseasesDisease Models AnimalTreatment OutcomeAnesthesiaVentricular fibrillationEmergency MedicineBreathingCardiology and Cardiovascular MedicinebusinessResuscitation
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Bulbar impairment score predicts noninvasive volume-cycled ventilation failure during an acute lower respiratory tract infection in ALS.

2015

Amyotrophic lateral sclerosis (ALS) patients can suffer episodes of lower respiratory tract infections (LRTI) leading to an acute respiratory failure (ARF) requiring noninvasive ventilation (NIV).To determine whether clinical or functional parameters can predict noninvasive management failure during LRTI causing ARF in ALS.A prospective study involving all ALS patients with ARF requiring NIV in a Respiratory Care Unit. NIV was provided with volume-cycled ventilators.63 ALS patients were included (APACHE II: 14.93±3.56, Norris bulbar subscore (NBS): 18.78±9.68, ALSFRS-R: 19.90±6.98, %FVC: 40.01±18.07%, MIC: 1.62±0.74L, PCF 2.51±1.15L/s, PImax -34.90±19.44cmH2O, PEmax 51.20±28.84cmH2O). In 73…

MaleSeverity of Illness Indexlaw.inventionFEV1/FVC ratiolawLower respiratory tract infectionOutcome Assessment Health CareMedicineHumansTreatment FailureMuscle SkeletalRespiratory Tract InfectionsAgedCOPDNoninvasive VentilationAPACHE IIRespiratory tract infectionsbusiness.industryAmyotrophic Lateral SclerosisRespiratory infectionMiddle Agedmedicine.diseasePrognosisIntensive care unitNeurologyRespiratory failureAnesthesiaAcute DiseaseFemaleNeurology (clinical)businessRespiratory InsufficiencyJournal of the neurological sciences
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Geoeconomic variations in epidemiology, ventilation management, and outcomes in invasively ventilated intensive care unit patients without acute resp…

2022

Contains fulltext : 252214.pdf (Publisher’s version ) (Open Access) BACKGROUND: Geoeconomic variations in epidemiology, the practice of ventilation, and outcome in invasively ventilated intensive care unit (ICU) patients without acute respiratory distress syndrome (ARDS) remain unexplored. In this analysis we aim to address these gaps using individual patient data of four large observational studies. METHODS: In this pooled analysis we harmonised individual patient data from the ERICC, LUNG SAFE, PRoVENT, and PRoVENT-iMiC prospective observational studies, which were conducted from June, 2011, to December, 2018, in 534 ICUs in 54 countries. We used the 2016 World Bank classification to defi…

MaleSociodemographic FactorsRespiration Artificial/methodsARDS ; mechanical ventilationSeverity of Illness IndexNOSettore MED/41 - ANESTESIOLOGIA80 and overTidal VolumeHumansHospital MortalityProspective Studiesddc:610Developing CountriesAgedHospital Mortality/trendsAged 80 and overDeveloped Countries/statistics & numerical dataDeveloping Countries/statistics & numerical dataRespirationDeveloped CountriesArticlesGeneral Medicineacute respiratory distress syndromeLength of StayMiddle AgedRespiration ArtificialIntensive Care UnitsObservational Studies as Topiclnfectious Diseases and Global Health Radboud Institute for Health Sciences [Radboudumc 4]Length of Stay/statistics & numerical dataArtificialIntensive Care Units/statistics & numerical dataIncomeFemaleARDS
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N-BiPAP vs n-CPAP in term neonate with respiratory distress syndrome

2020

Abstract Background Non-invasive respiratory ventilation has greatly improved the evolution of respiratory distress in neonates, especially for preterm infants, but few studies have investigated the use of non-invasive ventilation (NIV) in term infants. It is useful for neonatologists and nurses to identify the optimal ventilation strategy in terms of effectiveness for this group of newborns. The aim of our study was to investigate what type of respiratory support between nasal Continuous Positive Airway Pressure (nCPAP) or nasal Biphasic Positive Airway Pressure (nBiPAP) is more effective in term neonates with RDS. Methods Our study was a retrospective observational study of 78 full term n…

MaleTerm infantsRespiratory distress syndromemedicine.medical_treatmentContinuous positive airway pressureVital signsBiphasic positive airway pressureNOBiphasic Positive Airway PressurePositive-Pressure Respiration03 medical and health sciences0302 clinical medicine030225 pediatricsmedicineHumansBiphasic positive airway pressure; Continuous positive airway pressure; Non-invasive ventilation; Respiratory distress syndrome; Term infants;Continuous positive airway pressureRespiratory systemFull TermRespiratory Distress Syndrome NewbornNoninvasive VentilationRespiratory distressbusiness.industryInfant NewbornObstetrics and Gynecologyrespiratory systemmedicine.diseaseBiphasic positive airway pressure; Continuous positive airway pressure; Non-invasive ventilation; Respiratory distress syndrome; Term infantsTerm infants.PneumothoraxAnesthesiaPediatrics Perinatology and Child HealthNon-invasive ventilationBreathingFemalebusiness030217 neurology & neurosurgeryEarly Human Development
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Results of mitral valve repair for Barlow disease (bileaflet prolapse) via right minithoracotomy versus conventional median sternotomy: a randomized …

2011

Objective: The results of mitral repair for complex Barlow valves are adequate and support earlier intervention. It is unknown whether these results are reproducible in the context of minimally invasive surgery via right minithoracotomy. Methods: We randomized patients with Barlow mitral disease (bileaflet prolapse) to have conventional open repair via median sternotomy (MS group) or minimally invasive (MI group) repair. Repair was done using polytetrafluoroethylene chordal reimplantation for both leaflets. In the MI group, we adopted right minithoracotomy, peripheral cannulation, external aortic clamping, and surgery under direct vision. Results: Both groups comprised 70 patients. The oper…

MaleTime Factorsmedicine.medical_treatmentKaplan-Meier Estimatelaw.inventionlawRisk FactorsMitral valveCardiac Surgical ProcedureHospital MortalityProspective StudiesUltrasonographyPain PostoperativeMitral Valve ProlapseAtrial fibrillationGenetic Diseases X-LinkedMiddle Agedmedicine.anatomical_structureTreatment OutcomeItalyThoracotomyCardiologyMitral ValveFemaleCardiology and Cardiovascular MedicineHumanPulmonary and Respiratory MedicineAdultReoperationmedicine.medical_specialtyTime FactorContext (language use)Risk AssessmentInternal medicineCardiopulmonary bypassmedicineHumansCardiac Surgical ProceduresMechanical ventilationMitral valve repairMitral regurgitationChi-Square Distributionbusiness.industryRisk FactorPatient SelectionSettore MED/23 - Chirurgia Cardiacamedicine.diseaseSternotomySurgeryProspective StudieMedian sternotomySurgerybusinessThe Journal of thoracic and cardiovascular surgery
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Pulse wave transit time measurements of cardiac output in septic shock patients: a comparison of the estimated continuous cardiac output system with …

2015

Pôle EAMERSCT3Hors Enjeu; Background We determined reliability of cardiac output (CO) measured by pulse wave transit time cardiac output system (esCCO system; COesCCO) vs transthoracic echocardiography (COTTE) in mechanically ventilated patients in the early phase of septic shock. A secondary objective was to assess ability of esCCO to detect change in CO after fluid infusion. Methods Mechanically ventilated patients admitted to the ICU, aged > 18 years, in sinus rhythm, in the early phase of septic shock were prospectively included. We performed fluid infusion of 500ml of crystalloid solution over 20 minutes and recorded CO by EsCCO and TTE immediately before (T0) and 5 minutes after (T1) …

Malecritically-ill patientCardiac output[SDV]Life Sciences [q-bio]lcsh:MedicineHemodynamicsmulticenter030204 cardiovascular system & hematologysepsispressure0302 clinical medicineintensive-careMedicineProspective StudiesCardiac Outputlcsh:ScienceAged 80 and overObserver VariationMultidisciplinaryMiddle Agedventilated patientShock Septic[SDV] Life Sciences [q-bio]Treatment OutcomeEchocardiographyShock (circulatory)CardiologyFemalemedicine.symptomcritically-ill patient;fluid responsiveness;ventilated patient;intensive-care;respiratory change;dynamic index;multicenter;sepsis;thermodilution;pressureResearch Articlemedicine.medical_specialtyPulse Wave AnalysisPulse Wave Analysis03 medical and health sciencesdynamic indexIntensive careInternal medicinerespiratory changePulse Wave Transit Timefluid responsivenessHumansAgedMonitoring Physiologic[ SDV ] Life Sciences [q-bio]business.industrySeptic shocklcsh:RReproducibility of Results030208 emergency & critical care medicinemedicine.diseaseRespiration ArtificialSurgerythermodilutionBlood pressureFluid Therapylcsh:Qbusiness
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