Search results for "tools"
showing 10 items of 360 documents
Exosomal Hsp60 levels and related miRNA in brain tumor cells
2018
One of the many pathologic conditions still without a satisfactory solution is that of brain tumors. The prognosis is poor even after surgical resection followed by post-operatory chemo- and radio-therapie (1). It is, therefore, cogent to find innovative treatment tools. Three recent developments may provide elements to discover novel treatment strategies and means. These developments are: the discovery that molecular chaperones can be determinant factors in the process of tumorigenesis (2); the elucidation of the role of miRNAs in gene regulation and determination of protein functions, including molecular chaperones; in the various cell compartments (3);the increasing understanding and cha…
Hazards That Can Affect CNC Machine Tools during Operation—An AHP Approach
2020
CNC (computer numerically controlled) machine tools are highly advanced technological systems, used to machine parts by means of metal cutting processes. Their structure and kinematics are very complex, involving accurate coordinated motions on three to five axes. Operating CNC machine tools is a complicated process, which can easily be affected by errors. Nowadays, safety systems and devices are developed in order to make this process safer and more user friendly. Modern CNC controllers are designed to deal with obvious sources of hazards, such as overloads (by means of various sensor systems) and collisions (by checking the NC code syntax and simulating it on the machine). However, despit…
Planning integrated care at primary care centres: lessons learnt through research in stratification tools in the Valencian Healthcare System
2018
Introduction and policy context: In the Valencian Region social services and the healthcare system are not connected. Also there is not any normative jointly regulating resources, services or aid benefits that would mean an integrated care IC portfolio. Primary care PC centres are the closest and most trustworthy care facility for patients in the Spanish context. Also, PC is one of the most suitable resources to address needs of complex patients, as elderly and/or those with chronic conditions, through an IC approach, but there are some barriers that block its real and effective deployment. Objective and target population: Authors have studied the viability, implementation and development …
A PHENOMENOLOGICAL OPERATOR DESCRIPTION OF INTERACTIONS BETWEEN POPULATIONS WITH APPLICATIONS TO MIGRATION
2013
We adopt an operatorial method based on the so-called creation, annihilation and number operators in the description of different systems in which two populations interact and move in a two-dimensional region. In particular, we discuss diffusion processes modeled by a quadratic hamiltonian. This general procedure will be adopted, in particular, in the description of migration phenomena. With respect to our previous analogous results, we use here fermionic operators since they automatically implement an upper bound for the population densities.
Testing for goodness rather than lack of fit of an X–chromosomal SNP to the Hardy-Weinberg model
2019
The problem of checking the genotype distribution obtained for some diallelic marker for compatibility with the Hardy-Weinberg equilibrium (HWE) condition arises also for loci on the X chromosome. The possible genotypes depend on the sex of the individual in this case: for females, the genotype distribution is trinomial, as in the case of an autosomal locus, whereas a binomial proportion is observed for males. Like in genetic association studies with autosomal SNPs, interest is typically in establishing approximate compatibility of the observed genotype frequencies with HWE. This requires to replace traditional methods tailored for detecting lack of fit to the model with an equivalence test…
Forest management planning at different geographic levels in Italy: hierarchy, current tools and ongoing development
2009
This paper examines the current status of forest management tools and their pplication at different levels in Italy where the majority of land planning has been and is still being done at the “micro-scale”, meaning that specific local issues are dealt with locally. Starting from international European Union law, the authors review the forest acts that led from the National Forest Plan (NFP) to smaller scales, in relation to their geographic and territorial applicability. Scaling down from the NFP to the local level the various Italian forest programmes and plans are analysed according to a vertical logic (hierarchical mode): Regional Forest Programme (RFP), Territorial (i.e. sub-regional) F…
Using Slack for computer-mediated communication to support higher education students’ peer interactions during Master’s thesis seminar
2018
Our study contributes to the research on computer-mediated communication in higher education by experimenting a modern communication tool called Slack. In particular, we consider using Slack to support students’ peer interactions during Master’s thesis work. For this purpose, we designed a case study that was executed in a Master’s thesis seminar course. During the course, all out-of-class communication was carried out by using Slack, instead of e-mails or learning management systems. After the course, we used a questionnaire to investigate how the students perceived Slack for asking for assistance, their intention to use Slack, and Slack’s ease of use. Furthermore, the questionnaire asked …
Extracellular vesicles in parasitic diseases
2014
Parasitic diseases affect billions of people and are considered a major public health issue. Close to 400 species are estimated to parasitize humans, of which around 90 are responsible for great clinical burden and mortality rates. Unfortunately, they are largely neglected as they are mainly endemic to poor regions. Of relevance to this review, there is accumulating evidence of the release of extracellular vesicles (EVs) in parasitic diseases, acting both in parasite parasite inter-communication as well as in parasite host interactions. EVs participate in the dissemination of the pathogen and play a role in the regulation of the host immune systems. Production of EVs from parasites or paras…
The impact of Information Technology on the identification of species and archiviation of taxonomic and floristic data.
2007
In plant taxonomy, classification aims at reconstructing an evolutionary history, usually represented by means of phylogenetic trees. The approach followed by the classification is hierarchical, and rather in coherence with the dichotomies traditionally used for identifying a certain species. But classification and identification are different, since the latter just aims at finding the name of a specimen, eventually in order to get information on it. There are many ways to identify a specimen: to trace it back to its origin, by following the bifurcations of its phylogenetic tree is one possibility, but not always the easiest and quickest one. This theme has been touched during the symposium…
Analytical tools used for the identification and quantification of pectin extracted from plant food matrices, wastes and by-products: A review
2018
Pectin is the methylated ester of polygalacturonic acid and has a wide range of applications. It can be used in food and animal feed as well as in pharmaceutical and cosmetic products. Pectin is traditionally used as a gelling agent in fruit-based products, as a stabilizer in some fruit juices and milk drinks and fruit filling for bakery and confectionary products, but their potential applications differ according to their chemical composition. Therefore, at this stage of development, it is of a great importance to find fast, reliable methods to not only identify and quantify pectin, but also to determine its chemical structure and composition when it is extracted from plant matrices, waste…