Search results for "traditional medicine"

showing 10 items of 422 documents

Phytochemical profile and bioactivity of traditional ayurvedic decoctions and hydro-alcoholic macerations of Boerhaavia diffusa L. and Curculigo orch…

2015

Decoctions (DECs) and hydro-alcoholic extracts (HEs) prepared from roots of Boerhaavia diffusa L. (Nyctaginaceae) and Curculigo orchioides Gaertn. (Hypoxidaceae) were phytochemically characterised by HPLC-DAD and profiled for their antioxidant, antigenotoxic and cytotoxic activities. B. diffusa DEC was rich in ferulic acid and vanillin, while the HE also contained boeravinone B and eupalitin. Both C. orchioides HE and DEC displayed the main occurrence of orcinol-β-d-glucoside and curculigoside A. Antioxidant activity was assayed through spectrophotometric DPPH, ABTS and β-carotene bleaching test, and using (HP)TLC bioautographic strategies. For both crude drugs, HE was the best performing p…

DPPHPhytochemicalsantioxidant activityDecoctionPlant ScienceBiochemistryPlant RootsAntioxidantsAnalytical ChemistryNOchemical fingerprintingFerulic acidchemistry.chemical_compoundCurculigoPhenolsEupalitinCell Line TumorOrganic chemistryHumansCurculigosideBoerhaavia diffusa; Curculigo orchioides; traditional preparations; chemical fingerprinting; antioxidant activity; genotoxicity; cytotoxicitytraditional preparationsbiologyTraditional medicinePlant ExtractsCurculigo orchioidesOrganic Chemistrygenotoxicitybiology.organism_classificationAntineoplastic Agents PhytogenicCurculigo orchioidesMedicine AyurvedicHypoxidaceaeBoerhaavia diffusachemistrycytotoxicityChemical fingerprintingNyctaginaceae
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Traditionally used Thai medicinal plants: in vitro anti-inflammatory, anticancer and antioxidant activities.

2009

In order to assess traditional Thai claims about the therapeutic potential of medicinal plants and to select plants for future phytochemical research, nine plant species with anti-inflammatory uses were selected from Thai textbooks and assessed for their in vitro anti-inflammatory, antiproliferative and antioxidant activities.Nuclear factor-kappaB (NF-kappaB) inhibitory effects in stably transfected HeLa cells were determined by luciferase assay, and effects on LPS-induced pro-inflammatory mediators prostaglandin E2 (PGE2), interleukin (IL)-6, IL-1beta, and tumour necrosis factor (TNF)alpha in primary monocytes were assessed by ELISA. Cytotoxic activities were examined against HeLa cells, h…

DPPHmedicine.drug_classCell SurvivalInterleukin-1betaAnti-Inflammatory AgentsPharmacognosyAsteraceaeTransfectionAnti-inflammatoryAntioxidantsDinoprostoneMonocytesHeLachemistry.chemical_compoundInhibitory Concentration 50MagnoliopsidaPhenolsDrug DiscoveryMedicineHumansGynuraPharmacologyPlants MedicinalTraditional medicinebiologyDose-Response Relationship Drugbusiness.industryInterleukin-6Plant ExtractsTumor Necrosis Factor-alphaNF-kappa Bbiology.organism_classificationThailandOroxylum indicumAntineoplastic Agents PhytogenicPolygonaceaeRhinacanthus nasutusPhytochemicalchemistryDrug Resistance NeoplasmBignoniaceaeLipid PeroxidationMedicine TraditionalInflammation MediatorsbusinessHeLa CellsJournal of ethnopharmacology
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Genotoxicity of dental materials.

1996

This study was performed to characterize the (possible) DNA-damaging properties of dental materials and to identify specific compounds that contribute to this genotoxicity. For screening, three tests that assay for different aspects of genotoxicity (i) the bacterial umu-test; (ii) the eucaryotic DNA synthesis inhibition test; and (iii) the in vivo alkaline filter elution technique were chosen. This investigation gives several lines of evidence that most dental materials tested (14 chemical monosubstances present in dental devices and 7 extracts of dental materials) yield 'positive' results in at least one of the genotoxicity tests, however, with effects ranging from 'borderline' to 'strong …

Dental ceramicsTraditional medicinebusiness.industryPublic concernToxicologymedicine.disease_causeMicrobiologyBivalviastomatognathic diseasesDental MaterialsDental cementGeneticsMedicineAnimalsHumansbusinessGenotoxicityDNA DamageHeLa CellsMutagensMutation research
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Antibacterial Activity of Extracts from Some Bryophytes

2012

The antimicrobial activity of aqueous and ethanolic extracts of 11 Bryophyta species and 9 Marchantiophyta species collected in Latvia was tested against Staphylococcus aureus, Escherichia coli and Bacillus cereus. The extract of Lophocolea heterophylla inhibited the growth of B. cereus, but none of the tested extracts inhibited the growth of E. coli. 70% of bryophyte species demonstrated certain activity in relation to S. aureus. In general, 73% of ethanolic extracts and 39% of aqueous extracts exhibited antibacterial activity against S. aureus. The highest degree of antibacterial activity against S. aureus was shown by the ethanolic extract of Dicranum scoparium and aqueous extracts of At…

Dicranum scopariumbiologyTraditional medicineChemistryBacillus cereusGeneral MedicineFrullania dilatatabiology.organism_classificationAntimicrobialmedicine.disease_causeCereusStaphylococcus aureusRhytidiadelphus squarrosusmedicineAntibacterial activityAdvances in Microbiology
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Apple-products phytochemicals and processing: a review.

2009

Epidemiological studies have linked the consumption of apples with reduced risk of some cancers, cardiovascular disease, asthma, and diabetes. Extensive research exists on apples and the health benefits of their beverages and phytochemicals. The purpose of this paper is to review the most recent literature in this area focusing on phytochemicals, phytochemical bioavailability and antioxidant behavior.

Dietary FiberReduced riskFood HandlingPlant compositionBiological AvailabilityPlant ScienceHealth benefitsFood handlingAntioxidantsBeveragesPhenolsDrug DiscoveryMedicineHumansFood sciencePharmacologyTraditional medicinebusiness.industryGeneral MedicineComplementary and alternative medicinePhytochemicalFruitMalusDietary fiberbusinessBiological availabilityNatural product communications
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Nutraceuticals in Lipid-Lowering Treatment

2014

Lipid-lowering drugs may cause adverse effects and, although lipid targets may be achieved, a substantial residual cardiovascular (CV) risk remains. Treatment with agents mimicking proteins present in the body, such as incretin-based therapies, provided promising results. However, in order to improve lipids and CV risk, lifestyle measures remain important. Some researchers focused on nutraceuticals that may beneficially affect metabolic parameters and minimize CV risk. Chitosan, a dietary fiber, can regulate lipids with benefit on anthropometric parameters. The beneficial properties of dietary supplements (such as green tea extract, prebiotics, plant sterols, and stanols) on plasma lipids,…

Dietary Fibermedicine.medical_treatmentGreen tea extractPharmacologyChitosanchemistry.chemical_compoundNutraceuticallipidRisk FactorsmedicineAnimalsHumansAdverse effectDyslipidemiasHypolipidemic AgentsChitosanTraditional medicinebusiness.industryMedicine (all)InsulinlipoproteinLipidsClinical trialTreatment OutcomeBlood pressurechemistryCardiovascular Diseasesdietary supplementDietary SupplementsnutraceuticalLipid loweringCardiology and Cardiovascular MedicinebusinessBiomarkersAngiology
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Phytochemical profile and insecticidal activity of Drimia pancration (Asparagaceae) against adults of Stegobium paniceum (Anobiidae)

2020

Chemical and spectroscopic investigation of the bulbs of Drimia pancration resulted in the isolation of one known flavonol (1), never isolated from this plant species, and of three previously described steroidal saponins (2–4), but whose configuration at their stereogenic centres was not clearly determined. By mean of 1H NMR, 13C NMR, nuclear overhauser effects (NOE) and two-dimensional NMR spectra the full stereochemical structures of compounds 2–4 were proved and all the 1H and 13C signals were assigned. Furthermore, the methanol and butanol extracts of D. pancration were tested against adults of Stegobium paniceum beetles. Despite the non-significant results regarding the repellent activ…

Drimiasteroidal saponinsflavonolStegobium paniceumbiologyTraditional medicine010405 organic chemistryOrganic ChemistryinsecticideSettore CHIM/06 - Chimica OrganicaPlant Sciencebiology.organism_classification01 natural sciencesBiochemistry0104 chemical sciencesAnalytical Chemistry010404 medicinal & biomolecular chemistryAsparagaceaeAnobiidaePhytochemicalDrimia pancrationPlant speciesSettore BIO/15 - Biologia Farmaceutica
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Novel yeast extract is superior to colloidal oatmeal in providing rapid itch relief

2020

Background Approximately, 13.5% of the population suffers from chronic itch. Many cosmetic and pharmaceutical treatments for itch are available; however, cosmetic treatments are not reliably effective and most pharmaceutical formulations carry the risk of adverse events with chronic use. Aims Previously, we have reported a novel extraction process of Saccharomyces cerevisiae, that is, Baker's yeast. The extract obtained from the novel process demonstrates superior anti-itch properties compared to other yeast extracts. In our previous study, we demonstrated that, after 30 minutes, the extract significantly reduced itch when compared to a placebo lotion (P = .002). Methods In the present stud…

Drug CompoundingPopulationMarket leaderSaccharomyces cerevisiaeDermatology030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicineDouble-Blind Methodchronic effect ; cosmetic ; pruritisotorhinolaryngologic diseasesHumansYeast extractMedicineskin and connective tissue diseaseseducationColloidal oatmealeducation.field_of_studyEmollientsTraditional medicinebusiness.industryPruritusSignificant differenceItch ReliefYeast030220 oncology & carcinogenesisLotionbusinessJournal of Cosmetic Dermatology
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In vitro activities of antimicrobial agents against Candida species

1999

Objective. Antimicrobial mouthrinses may represent a valid alternative to topical antifungal agents. However, the action of antimicrobials could be affected by the different ingredients incorporated into mouthrinse products. The purpose of the present study was to investigate the in vitro antifungal and fungicidal activities of antimicrobials alone. Study Design. A broth macrodilution method was used to determine the minimum inhibitory concentration of 4 antimicrobial agents against Candida species. Minimum fungicidal concentration was also determined. Results. All antimicrobials showed antifungal activity against all tested organisms, but cetylpyridinium chloride received significantly low…

DrugAntifungal Agentsmedia_common.quotation_subjectColony Count MicrobialMouthwashesCetylpyridiniumMicrobial Sensitivity TestsHexetidineBiologyCetylpyridinium chlorideStatistics NonparametricMicrobiologychemistry.chemical_compoundMinimum inhibitory concentrationAlkaloidsmedicineGeneral DentistryMycosisCandidamedia_commonBenzophenanthridinesAnalysis of VarianceDose-Response Relationship DrugTraditional medicineChlorhexidineHexetidineFungi imperfectiIsoquinolinesmedicine.diseasebiology.organism_classificationAntimicrobialFungicideOtorhinolaryngologychemistryAnti-Infective Agents LocalSurgeryOral SurgeryOral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology
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Cytotoxicity of aloe-emodin towards several drug sensitive cells and their resistant counterparts

2017

DrugChemical engineeringTraditional medicinebusiness.industrymedia_common.quotation_subjectmedicinebusinessCytotoxicityAloe emodinmedicine.drugmedia_common65th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA 2017)
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