Search results for "traffic"

showing 10 items of 598 documents

Fog Computing based traffic Safety for Connected Vulnerable Road Users

2019

Annually, millions of people die and many more sustain non-fatal injuries because of road traffic crashes. Despite multitude of countermeasures, the number of causalities and disabilities owing to traffic accidents are increasing each year causing grinding social, economic, and health problems. Due to their high volume and lack of protective-shells, more than half of road traffic deaths are imputed to vulnerable road users (VRUs): pedestrians, cyclists and motorcyclists. Mobile devices combined with fog computing can provide feasible solutions to protect VRUs by predicting collusions and warning users of an imminent traffic accident. Mobile devices’ ubiquity and high computational capabilit…

Efficacité énergétiqueTrust Management and Security[INFO.INFO-MC] Computer Science [cs]/Mobile ComputingEnergy EfficiencyPosition accuracy and predictionPrécision de position géographique et taux d'échantillonnageTraffic SafetyFog ComputingGestion de confiance et sécuritéUsagers vulnérables de la routeVulnerable road usersSécurité routière
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Alteraciones del sueño producidas por el ruido ambiental*

1989

ResumenEste articulo presenta los resultados de una encuesta realizada con el objetivo de valorar distintos aspectos relacionados con el ruido ambiental y sus efectos sobre determinadas comunidades urbanas. Un total de 263 residentes en 5 emplazamientos diferentes de la ciudad de Valencia fueron entrevistados. En estos 5 emplazamientos se realizaron de manera independiente una serie de medidas de los niveles de ruido durante las 24 horas del dia y en distintos días de la semana.:El 400%0 de los encuestados manifestó tener alguna dificultad para dormirse y el 59% de ellos lo atribuyó al ruido causado por el tráfico. Asimismo, un 49% de los encuestados declaró despertarse durante la noche (el…

EncuestaNoiseEnvironmental healthAmbient noise levelTraffic noisePublic Health Environmental and Occupational HealthSleep disturbancesAmbient noiseRuido ambientalSurveyPsychologyAlteraciones del sueñoUrban healthGaceta Sanitaria
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Flotillin-involved uptake of silica nanoparticles and responses of an alveolar-capillary barrier in vitro

2013

AbstractDrug and gene delivery via nanoparticles across biological barriers such as the alveolar-capillary barrier of the lung constitutes an interesting and increasingly relevant field in nanomedicine. Nevertheless, potential hazardous effects of nanoparticles (NPs) as well as their cellular and systemic fate should be thoroughly examined. Hence, this study was designed to evaluate the effects of amorphous silica NPs (Sicastar) and (poly)organosiloxane NPs (AmOrSil) on the viability and the inflammatory response as well as on the cellular uptake mechanisms and fate in cells of the alveolar barrier. For this purpose, the alveolar epithelial cell line (NCI H441) and microvascular endothelial…

EndosomeCell SurvivalLipid BilayersPharmaceutical ScienceGene deliverysilica nanoparticlesEndocytosisClathrinNP transportCell LineDrug Delivery SystemsAlveolar-capillary barrierAlveolar capillary barrierElectric ImpedanceHumansColoring AgentsInflammationFlotillin-1/-2-dependent uptake/traffickingbiologyChemistryRhodaminesVesicleMicrocirculationEndothelial CellsMembrane ProteinsGeneral Medicinerespiratory systemSilicon DioxideNP uptakeIn vitroCoculture TechniquesEndocytosisCapillariesEndothelial stem cellPulmonary AlveoliNP-transportNanomedicineCell cultureImmunologybiology.proteinBiophysicsNanoparticlesBiotechnologyEuropean Journal of Pharmaceutics and Biopharmaceutics
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Calpains promote α2β1 integrin turnover in nonrecycling integrin pathway

2012

A novel virus- and integrin clustering–specific pathway diverts integrin from its normal endo/exocytic traffic to a nonrecycling degradative endosomal route. Clustering of α2β1 integrin causes redistribution of the integrin to perinuclear endosomes, leading to enhanced integrin turnover promoted by calpains.

EndosomeIntegrinCD18Medical and Health SciencesCD49cCell LineCollagen receptorFocal adhesion03 medical and health sciencesCell Line TumorHumansMolecular Biology030304 developmental biology0303 health sciencesFocal AdhesionsTumorbiologyCalpain030302 biochemistry & molecular biologyCell MembraneCell BiologyArticlesBiological Sciences3. Good healthCell biologyEnterovirus B HumanProtein TransportIntegrin alpha MMembrane Traffickingbiology.proteinIntegrin beta 6Enterovirus BIntegrin alpha2beta1HumanDevelopmental BiologySignal TransductionMolecular Biology of the Cell
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The endocytic trafficking pathway of oncogenic papillomaviruses

2019

Over the last two decades many host cell proteins have been described to be involved in the process of infectious entry of oncogenic human papillomaviruses (HPV). After initial binding and priming of the capsid, a sequence of events on the cell surface precedes the formation of the HPV entry platform. It has been shown that the virus-associated entry complex consists of membrane organizers, tetraspanins CD151 and CD63, and their associated partner proteins such as integrins, growth factor receptors, and the annexin A2 heterotetramer. Further recruitment of cytoplasmic factors such as the obscurin-like protein 1 and actin results in a non-canonical clathrin-independent endocytosis of the vir…

EndosomevirusesIntegrinEndocytic cycleAnnexinEndocytosisArticlelcsh:Infectious and parasitic diseasesEntry receptor complex03 medical and health sciences0302 clinical medicineTetraspaninViral entryVirologyHumansMedicinelcsh:RC109-216030212 general & internal medicineHuman papillomavirus 16Traffickingbiologybusiness.industryPapillomavirus InfectionsBiological TransportVirus InternalizationTetraspaninEndocytosisVirusCell biologyInfectious DiseasesCapsid030220 oncology & carcinogenesisHost-Pathogen Interactionsbiology.proteinbusinessAnnexin A2Papillomavirus Research
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The Community Response to Aircraft Noise Around Six Spanish Airports

1993

Abstract The community response to aircraft noise has been studied through a social survey. A total of 1800 persons living in the vicinity of six major Spanish airports have been interviewed at their homes concerning the environmental quality of the area, dissatisfaction with road traffic noise and aircraft noise, activities interfered with by noise, most disturbing aircraft types, and subjective evaluation of airport impact. All the responses obtained in this survey have been compared with aircraft noise levels corresponding to the residence locations of the people interviewed (values of NEF levels were calculated with the INM model). The results obtained in this work allow one to evaluate…

EngineeringAcoustics and UltrasonicsAircraft noiseNoise pollutionbusiness.industryMechanical EngineeringNoise reductionTraffic noiseCondensed Matter PhysicsGeneral Social SurveyNoiseAeronauticsMechanics of MaterialsRange (aeronautics)businessTelecommunicationsEnvironmental qualityJournal of Sound and Vibration
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Is naturalistic driving research possible with highly instrumented cars? Lessons learnt in three research centres.

2011

This paper provides an overview of the experiences using Highly Instrumented Cars (HICs) in three research Centres across Europe; Spain, the UK and Greece. The data collection capability of each car is described and an overview presented relating to the relationship between the level of instrumentation and the research possible. A discussion then follows which considers the advantages and disadvantages of using HICs for ND research. This includes the obtrusive nature of the data collection equipment, the cost of equipping the vehicles with sophisticated Data Acquisition Systems (DAS) and the challenges for data storage and analysis particularly with respect to video data. It is concluded th…

EngineeringAutomobile DrivingData collectionInjury controlGreecebusiness.industryAccident preventionData CollectionPublic Health Environmental and Occupational HealthAccidents TrafficPoison controlHuman Factors and ErgonomicsUnited KingdomTransport engineeringData acquisitionSpainHumansInstrumentation (computer programming)Naturalistic drivingSafety Risk Reliability and QualitybusinessAutomobilesAccident; analysis and prevention
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Modeling traffic safety at urban four leg-signalized intersections

2013

According to the state-of-the-art of the methodologies, the development of safety performance functions (SPFs) for road sections and intersections requires the employment of statistical models to predict expected crash frequencies on the basis of traffic volumes and site characteristics to be surveyed and used as input to models. Nevertheless, literature reports several studies on issues deriving from data features or methodological approaches that may invalidate the efficiency of the models and the accuracy of the estimates. Drawing inspiration from the above mentioned considerations, the objective of this study is to develop safety performance functions for a sample of urban four leg-sign…

EngineeringBasis (linear algebra)urban signalized intersectionsbusiness.industryCrashSample (statistics)Statistical modelTemporal correlationtransportation safetyTransport engineeringcrash analysissafety performance functionTraffic crashSettore ICAR/04 - Strade Ferrovie Ed AeroportiStatistical dispersionCrash databusiness
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Performance Analysis of Basic Turbo-Roundabouts in Urban Context

2012

AbstractA turbo roundabout is a new type of canalized multilane intersection in which the physical separation between lanes helps to prevent side collisions when crossing the roundabout. This paper presents an estimation of capacity, delays and level of service of basic turbo roundabouts in undersaturation conditions, considering both vehicle flow and pedestrian traffic. The traffic performance model was developed by evaluating the capacity for each entry lane. Owing to the geometric features of the intersection, the total entry capacity is obtained by considering different values of the pedestrian impedance factor and degree of saturation at both the right-turn and left-turn lanes.

EngineeringDelaybiologyCapacitybusiness.industryLevel of serviceTurboDegree of saturationPoison controlContext (language use)Traffic flowbiology.organism_classificationTransport engineeringIntersectionTurbo roundaboutsRoundaboutTurbo roundabouts pedestrians capacity delay level of serviceSettore ICAR/04 - Strade Ferrovie Ed AeroportiGeneral Materials SciencebusinessLevel of servicePedestrians
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Influence of the Hourly Variation of Temperature on the Estimation of Fatigue Damage and Rutting in Flexible Pavement Design

2004

The work presented in this paper offers a contribution to understand to what extent different discretization modes for describing a whole day can affect the estimation of in-service durability of a flexible pavement, in relation with concomitant traffic flow fluctuations. Calculation of the stress–strain state was carried out with an elastic multi-layer model, and performance laws were implemented for verification of the major distress mechanisms that are able to affect the prediction of a flexible pavement’s service life. Results from the prediction of the fatigue life allow one to conclude that no big mistakes are made when evaluating the total damage by describing climatic conditions via…

EngineeringDiscretizationRutbusiness.industryWork (physics)Structural engineeringDeformation (meteorology)Traffic flowDurabilityTEMPERATURE FLEXIBLE PAVEMENT RUTTING CRACKINGMechanics of MaterialsAsphaltService lifebusinessCivil and Structural EngineeringInternational Journal of Pavement Engineering
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