Search results for "translatio"
showing 10 items of 1331 documents
Regulation of NOS expression in vascular diseases
2020
Nitric oxide synthases (NOS) are the major sources of nitric oxide (NO), a small bioactive molecule involved in the regulation of many cellular processes. One of the most prominent functions of NO is regulation of vasodilatation and thereby control of blood pressure. Most important for vascular tone is NOS3. Endothelial NOS3-generated NO diffuses into the vascular smooth muscle cells, activates the soluble guanylate cyclase resulting in enhanced cGMP concentrations and smooth muscle cell relaxation. However, more and more evidence exist that also NOS1 and NOS2 contribute to vascular function. We summarize the current knowledge about the regulation of NOS expression in the vasculature by tra…
Membrane topology and post-translational modification of the Saccharomyces cerevisiae essential protein Rot1.
2007
ROT1 is an essential gene that has been related to cell wall biosynthesis, the actin cytoskeleton and protein folding. In order to help to understand its molecular function, we carried out a characterization of the Rot1 protein. It is primarily located at the endoplasmic reticulum-nuclear membrane facing the lumen. Rot1 migrates more slowly than expected, which might suggest post-translational modification. Our results indicate that Rot1 is a protein that is neither GPI-anchored nor O-glycosylated. In contrast, it is N-glycosylated. By a directed mutagenesis of several Asn residues, we identified that the protein is simultaneously glycosylated at N103, N107 and N139. Although the mutation o…
Biophotonics in veterinary medicine: the first steps toward clinical translation
2019
In this paper, we analyzed the current situation and the potential of biophotonics and biomedical optics in veterinary medicine. Promising optical techniques such as optical coherence tomography, pulse oximeter, and hyperspectral imaging have been clinically translated into human medicine. But even though human and small animal medicine share personalized and state-of-the-art approach, biophotonics remains rarely exploited in the canine and feline medicine. However, there are some biophotonics studies in veterinary oncology which addressed tumor diagnosis (skin and subcutaneous tumors), prognosis (lymphoma), and therapy (clear surgical margins). Visible and near-infrared spectroscopy served…
Polish Translations of Anglo-American Literature and the Question of Ideology : From Romanticism to Twentieth-Century Avant-Gardes
2017
Ideology has always influenced translation, yet this fact became a topic of scholarly research only in the 1990s. The working of ideology in literary translations most often manifests itself as a conflict of value systems. From vast reservoir of foreign sources, the native axiology absorbs values that it needs to sustain its culture. It is not a coincidence that Anglo-American literature, propagating ideas of democracy and individual freedom, became popular in Poland in the first half of the nineteenth-century when Poland did not exist as a state. Only a century later, American literature was the most popular of all foreign literatures in pre-1939 Poland. World War II changed this situation…
Fat storing cells (FSC) of rat liver synthesize and secrete fibronectin
1987
Summary Fat storing cells (FSC) of rat liver were isolated and kept in culture for up to 2 weeks. Freshly isolated cells and cells in culture were characterized functionally (vitamin A content) and morphologically. Their synthetic capacity for fibronectin was studied quantitatively by ELISA-measurement and qualitatively by biosynthetic labeling, immunoprecipitation and SDS-PAGE analysis. The synthesis product and the kinetics of the synthesis and secretion were compared with those obtained from culture of hepatocytes. FSC were shown to synthesize and secrete fibronectin under the culture conditions used. No fibronectin synthesis was detected during the first 3 days of culture. Thereafter th…
Improving Classification of Tweets Using Linguistic Information from a Large External Corpus
2016
The bag of words representation of documents is often unsatisfactory as it ignores relationships between important terms that do not co-occur literally. Improvements might be achieved by expanding the vocabulary with other relevant word, like synonyms.
Zum Zusammenspiel von Textsorten-und Kulturspezifika in der Übersetzung von Weinbesprechungen
2017
International audience; FragestellungWeinbesprechungen stellen für Weinliebhaber – aber auch für Winzer und Weinhändler – eine wichtige Informationsquelle dar, um Wein zu kaufen bzw. zu bewerben (Lehrer 1975, Suárez-Toste 2007, Wislocka Breit 2014, Gautier/Lavric 2015). Vor dem Hintergrund einer Globalisierung des Weinhandels werden diese Texte immer öfter übersetzt, was zur folgenden Frage führt: Wie wird im Übersetzungsprozess mit der Textsorten- und Kulturspezifik dieser Textsorte umgegangen?-Auf Textsortenebene weisen Weinbesprechungen sowohl übereinzelsprachliche, als auch sprachspezifische Züge auf: Sie reihen sich somit in bestimmte Diskurstraditionen (s. unten) ein, die sich in Ausg…
Mujeres e Ilustración: una perspectiva europea
2008
Este artículo sitúa la relación entre mujeres e Ilustración en España dentro de su contexto internacional, desde un tripe enfoque: en primer lugar, situando la trayectoria de los estudios en el marco de la historiografía europea y norteamericana; en segundo lugar, señalando las conexiones entre los debates acerca de la naturaleza y funciones de los sexos dentro y fuera de nuestras fronteras (a través de traducciones, citas e influencias mutuas) y, por último, revisando cómo para ls gentes de la época las relaciones entre hombres y mujeres constituyeron un elemento clave a la hora de valorar las diferencias nacionales y el grado de civilización alcanzado por una sociedad. En este sentido, se…
Women-translators in Russia
2011
The paper considers the history of women’s involvement in translation in Russia. The emphasis is laid on social issues of women translators’ work. The main problems discussed are as follows: How have women contributed to social and literary processes? To what extent were translational activities of women different and/or separate from those of men? Women participated in all major social processes in Russian and Soviet history. From the eighteenth century onwards to the present day, they have been involved in translational work and other types of social-systemic transfer (primarily from the West). Women played their role of translators in the same spheres where men did.
SisHiTra : A Hybrid Machine Translation System from Spanish to Catalan
2004
In the current European scenario, characterized by the coexistence of communities writing and speaking a great variety of languages, machine translation has become a technology of capital importance. In areas of Spain and of other countries, coofficiality of several languages implies producing several versions of public information. Machine translation between all the languages of the Iberian Peninsula and from them into English will allow for a better integration of Iberian linguistic communities among them and inside Europe. The purpose of this paper is to show a machine translation system from Spanish to Catalan that deals with text input. In our approach, both deductive (linguistic) and…