Search results for "triazol"
showing 10 items of 598 documents
1,1′-[2,3,5,6-Tetramethyl-p-phenylenebis(methyleneoxy)]di-1H-benzotriazole
2009
The complete molecule of the title compound, C(24)H(24)N(6)O(2), is generated by a crystallographic inversion centre. The benzotriazole rings form dihedral angles of 2.10 (7)° with the central aromatic ring. The crystal packing is consolidated by π-π inter-actions, with centroid-centroid distances of 3.6234 (10) Å, together with weak C-H⋯π inter-actions.
1-(2,3,5,6-Tetramethylbenzyloxy)-1H-benzotriazole
2009
In the title compound, C17H19N3O, the benzotriazole ring is essentially planar, with a maximum deviation of 0.0069 (15) Å. The mean plane of the benzotriazole ring forms a dihedral angle of 13.16 (4)° with the mean plane of the benzene ring. The crystal packing is stabilized by π–π stacking interactions, with a centroid–centroid distance of 3.8077 (12) Å, together with weak C—H...π interactions. Molecules are stacked along the a axis.
N-(5-Amino-1H-1,2,4-triazol-3-yl)pyridine-2-carboxamide
2013
The title compound, C8H8N6O, was obtained by the reaction of 3,5-diamino-1,2,4-triazole with ethyl 2-picolinate in a glass oven. The dihedral angles formed between the plane of the amide group and the pyridine and triazole rings are 11.8 (3) and 5.8 (3)°, respectively. In the crystal, an extensive system of classical N—H...N and N—H...O hydrogen bonds generate an infinite three-dimensional network.
A C(π-hole)⋯Cl-Zn tetrel interaction driving a metal-organic supramolecular assembly
2020
A brominated pyrimidinyl triazolopyridine ligand (bptpy) forms a C(π-hole)⋯Cl-Zn tetrel interaction that plays a determining role in the formation of supramolecular layers through chain assembly in 18 membered metallacycle [(ZnCl2)2(μ-bptpy)2] crystals. Supramolecular chains are formed through C-H⋯X interactions. The observed interactions are supported by DFT calculations using model dimers. This journal is
Synthesis and crystal structures of two novel triazolopyridine compounds solved by local L.S. minimizations from powder diffraction data
2014
The heteroaryl-substituted triazolopyridines 3-phenyl-7-(pyrazin-2-yl)-[1,2,3]triazolo[1,5-a]pyridine (2) and 3-[6-(pyridazin-3-yl)-pyridin-2-yl]-[1,2,3]triazolo[1,5-a]pyridine (4) have been synthesized and characterized (by HRMS, IR,1H and13C NMR, XRPD, melting point). The crystal structures have been solved from laboratory powder X-ray diffraction data with the direct-space strategy TALP for molecular compounds based on fast local least-squares minimizations. The crystal structure confirmed the formation of the tridentate compound4from a ring chain isomerization process. The almost planar arrangement of atoms in both the structures favors the presence of intermolecularπ–πinteractions, alt…
1-[2-(2,4-Dichlorophenyl)pentyl]-1H-1,2,4-triazole
2009
The title compound, C13H15Cl2N3, also known as penconazole, crystallizes as a racemate. The dihedral angle between the benzene and triazole rings is 24.96 (13)°. In the crystal structure, molecules are linked into chains running parallel to the c axis by intermolecular C—H...N hydrogen-bonding interactions.
New polynuclear 4,4ˈ-bis-1,2,4-triazole Fe(II) spin crossover compounds
2001
L'interet porte aux materiaux moleculaires du Fe(II) presentant une transition entre un etat haut-spin (HS, S = 2) et un etat bas-spin (LS, S = 0), sous l'effet d'une variation de temperature, de pression ou d'une irradiation lumineuse, n'a cesse de croitre au cours de ces dix dernieres annees [1-4]. La famille des composes du Fe(II) a base de derives du 1,2,4-triazole substitues par un groupe R sur l'azote 4 a ete tres etudiee pour ses proprietes de transition de spin (TS), qui pourraient permettre des applications en electronique moleculaire [5-15, 29, 32, 36, 37]. Nous avons recemment presente le premier compose a TS possedant une structure tridimensionnelle (figure 2). Ce compose de for…
Nanowire iron(III) coordination polymer based on 1,2,4-triazolo[1,5-a]pyrimidine and chloride ligands
2019
Abstract The neutral ligand 1,2,4-triazolo[1,5-a]pyrimidine (tp) has been employed to prepare a new coordination compound of Fe(III), [FeCl3(tp)2]n (1). Compound 1 was investigated by single crystal X-ray diffraction and found to be a coordination polymer forming a ladder structure based on metal–ligand interactions, while H-bonding and aromatic interactions contribute to the supramolecular self-assembly into a 3D nanostructured material. The polymeric assembly is retained also in solution, where a metallo-supramolecular polymer based on coordinative metal–ligand binding is present, as shown by dynamic light scattering (DLS) measurements. The redox properties of the Fe(III) coordination pol…
ω-Hetarilbutānskābes atvasinājumu iegūšana pretvēža aktivitātes noteikšanai: pieclocekļu heterocikli ar trim heteroatomiem.
2022
ω-Hetarilbutānskābes atvasinājumu iegūšana pretvēža aktivitātes noteikšanai: pieclocekļu heterocikli ar trim heteroatomiem. Fiļipčuks M., zinātniskais vadītājs Dr. chem. Kļimenkovs I. Bakalaura darbs, 37 lappuses, 35 attēli, 1 tabula, 33 literatūras avoti, 19 pielikumi. Latviešu valodā. Bakalaura darba ietvaros tika izpētītas un aprakstītas diaizvietotu pieclocekļu heterociklisko savienojumu ar trim heteroatomiem iegūšanas iespējas.
Cytotoxic Activity of Organotin(IV) Derivatives with Triazolopyrimidine Containing Exocyclic Oxygen Atoms
2020
In this study cytotoxicity of organotin(IV) compounds with 1,2,4-triazolo[1,5-a]pyrimidines, Me3Sn(5tpO) (1), n-Bu3Sn(5tpO) (2), Me3Sn(mtpO) (3), n-Bu3Sn(mtpO) (4), n-Bu3Sn(HtpO2) (5), Ph3Sn(HtpO2) (6) where 5HtpO = 4,5-dihydro-5-oxo-[1,2,4]triazolo-[1,5-a]pyrimidine, HmtpO = 4,7-dihydro-5-methyl-7-oxo-[1,2,4]triazolo-[1,5-a]pyrimidine, and H2tpO2 = 4,5,6,7-tetrahydro-5,7- dioxo-[1,2,4]triazolo-[1,5-a]-pyrimidine, was assessed on three different human tumor cell lines: HCT-116 (colorectal carcinoma), HepG2 (hepatocarcinoma) and MCF-7 (breast cancer). While 1 and 3 were inactive, compounds 2, 4, 5 and 6 inhibited the growth of the three tumor cell lines with IC50 values in the submicromolar …