Search results for "uno"

showing 10 items of 14944 documents

Investigating candidate neuromodulatory systems underlying parasitic manipulation: concepts, limitations and prospects.

2012

Summary Studies addressing the functional basis of parasitic manipulation suggest that alteration of the neuromodulatory system is a common feature of manipulated hosts. Screening of the neuromodulatory system has so far been carried out by performing ethopharmacological analysis, biochemical quantification of neurotransmitters and neuromodulators, and/or immunocytochemistry. Here, we review the advantages and limitations of such approaches through the analysis of case studies. We further address whether the analysis of candidate neuromodulatory systems fits the current view of manipulation as being multidimensional. The benefits in combining ethopharmacology with more recent molecular tool…

0106 biological sciences[ SDV.MP.PAR ] Life Sciences [q-bio]/Microbiology and Parasitology/ParasitologyNeuroimmunomodulationPhysiologyMultidisciplinary studyAquatic ScienceBiology010603 evolutionary biology01 natural sciencesHost-Parasite Interactions03 medical and health sciences[ SDV.EE.IEO ] Life Sciences [q-bio]/Ecology environment/SymbiosisAnimalsHumansParasites[SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/ParasitologyParasite transmissionMolecular BiologyEcology Evolution Behavior and Systematics030304 developmental biologyethopharmacologyBehavior0303 health sciences[ SDE.BE ] Environmental Sciences/Biodiversity and EcologyneuroethologypsychoneuroimmunologyBiological evolutionBiological EvolutionserotoninInsect Sciencephenotypic engineeringAnimal Science and Zoology[SDE.BE]Environmental Sciences/Biodiversity and EcologyNeurosciencebehavioural manipulation[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/Symbiosis
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Immunity and Virulence in Bird-Parasite Interactions.

2010

8 pages; International audience; The interaction between hosts and parasites is characterized by the evolution of reciproca adaptations aiming at reducing the cost of infection (from the host point of view) and to optimize host exploitation (from the parasite point of view). Within this co-evolutionary scenario, the immune system takes a central role. The immune system has evolved to fight off parasitic attacks. However, immune defences cannot be deployed without costs which set a limit to the protective effect of immunity. Moreover, immune defences impose strong selection pressures on the parasite and can favour the evolution of more virulent pathogen strains. In this article, we will disc…

0106 biological sciences[ SDV.MP.PAR ] Life Sciences [q-bio]/Microbiology and Parasitology/ParasitologyVirulenceBiology[ SDV.IMM.IA ] Life Sciences [q-bio]/Immunology/Adaptive immunology010603 evolutionary biology01 natural sciencesimmune response03 medical and health sciencesImmune systemImmunityImmunopathology[ SDV.EE.IEO ] Life Sciences [q-bio]/Ecology environment/SymbiosisParasite hostingimmunopathology[SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/ParasitologyPathogenCoevolution030304 developmental biology0303 health sciences[ SDE.BE ] Environmental Sciences/Biodiversity and EcologyHost (biology)biochemical phenomena metabolism and nutritioninfectionvirulence[SDV.IMM.IA]Life Sciences [q-bio]/Immunology/Adaptive immunologyEvolutionary biologyImmunologybacteriaAnimal Science and Zoology[SDE.BE]Environmental Sciences/Biodiversity and Ecology[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/SymbiosisCoevolution
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Interpreting immunological indices: the importance of taking parasite community into account. An example in blackbirds Turdus merula.

2015

13 pages; International audience; Despite the intensive use of immune indices in immunoecology, whether to interpret the results of immune indices in terms of actual immune competence (i.e. ability to control and clear parasite infections as indicated by high values of immune indices associated with low parasite loads) or current immune activation (pathogenic infection being associated with high parasite load and high values of immune indices) is still an open question. Most studies to date have produced contrasting results focused on the effect of a single parasite species despite the fact that hosts usually harbour a community of parasites that influences one another's impact on host immu…

0106 biological sciences[ SDV.MP.PAR ] Life Sciences [q-bio]/Microbiology and Parasitology/Parasitologyanimal diseaseschemical and pharmacologic phenomenaongoing infectionBiologyintestinal parasites010603 evolutionary biology01 natural sciencesParasite load03 medical and health sciencesImmune system[ SDV.EE.IEO ] Life Sciences [q-bio]/Ecology environment/Symbiosis[ SDV.IMM ] Life Sciences [q-bio]/ImmunologyParasite hostingParasite Infections[SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/ParasitologyBlood parasitesEcology Evolution Behavior and Systematicsimmunoecology030304 developmental biology[ SDE.BE ] Environmental Sciences/Biodiversity and Ecology0303 health sciencesimmunocompetenceEcological ModelingSignificant partbiochemical phenomena metabolism and nutrition3. Good healthbirdsImmunologyparasite communitybacteria[SDV.IMM]Life Sciences [q-bio]/ImmunologyImmunocompetence[SDE.BE]Environmental Sciences/Biodiversity and EcologyImmune activationimmune assay[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/Symbiosis
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Parasite and host assemblages: embracing the reality will improve our knowledge of parasite transmission and virulence.

2010

10 pages; International audience; Interactions involving several parasite species (multi-parasitized hosts) or several host species (multi-host parasites) are the rule in nature. Only a few studies have investigated these realistic, but complex, situations from an evolutionary perspective. Consequently, their impact on the evolution of parasite virulence and transmission remains poorly understood. The mechanisms by which multiple infections may influence virulence and transmission include the dynamics of intrahost competition, mediation by the host immune system and an increase in parasite genetic recombination. Theoretical investigations have yet to be conducted to determine which of these…

0106 biological sciences[ SDV.MP.PAR ] Life Sciences [q-bio]/Microbiology and Parasitology/Parasitologymulti-parasitized hostsmedia_common.quotation_subjectEcology (disciplines)Virulenceinterspecies transmissionBiologyModels Biological010603 evolutionary biology01 natural sciencesGeneral Biochemistry Genetics and Molecular BiologyCompetition (biology)Host-Parasite InteractionsInterspecies transmission03 medical and health sciencesParasitic Diseases[ SDV.EE.IEO ] Life Sciences [q-bio]/Ecology environment/SymbiosisAnimalsParasite hostingParasites[SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/ParasitologyReview Articles030304 developmental biologyGeneral Environmental Sciencemedia_common0303 health sciences[ SDE.BE ] Environmental Sciences/Biodiversity and EcologyVirulenceGeneral Immunology and MicrobiologyEcologyTransmission (medicine)Host (biology)General MedicineBiological EvolutionObligate parasiteimmune systemEvolutionary biologymulti-host parasitesintrahost competitionepidemiology[SDE.BE]Environmental Sciences/Biodiversity and EcologyGeneral Agricultural and Biological Sciences[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/Symbiosis
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The Potential Role of Medicinal Mushrooms in the Prevention and Treatment of Gynecological Cancers: A Review

2019

A review of scientific information about the potential role of medicinal mushrooms in the prevention and treatment of gynecological cancers, human immunodeficiency virus, and human papillomavirus infections is reported here. The results of in vivo and in vitro experiments on 16 different species of Basidiomycetes and three Ascomycetes, which possess chemopreventive potential and are effective in clinical application in combination with chemotherapy, are also discussed. Medicinal mushroom extracts confirm an evident efficacy on the reduction of tumor cell proliferation and side effects in patients with gynecological tumors who are undergoing chemotherapy treatments. This review, the first on…

0106 biological sciencesanimal structuresVaginal NeoplasmsGenital Neoplasms Femalemedicine.medical_treatmentHuman immunodeficiency virus (HIV)Uterine Cervical NeoplasmsTumor cellsmedicine.disease_cause01 natural sciencesApplied Microbiology and BiotechnologyAntioxidantsMiceMedicinal mushroomAscomycotaIn vivo010608 biotechnologyDrug DiscoverymedicineAnimalsHumansIn patientHuman papillomavirusPapillomaviridaeCell ProliferationPharmacologyChemotherapyBiological ProductsClinical Trials as Topicbusiness.industryBasidiomycotafungiHIVSettore BIO/03 - Botanica Ambientale E ApplicataCancer researchFemalebusinessAgaricalesmedicinal mushrooms gynecological cancers human immunodeficiency virus human papillomavirus Basidiomycetes Ascomycetes
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Negative associations between parasite avoidance, resistance and tolerance predict host health in salmonid fish populations

2020

Genetic variation in defence against parasite infections is fundamental for host–parasite evolution. The overall level of defence of a host individual or population includes mechanisms that reduce parasite exposure (avoidance), establishment (resistance) or pathogenicity (tolerance). However, how these traits operate and evolve in concert is not well understood. Here, we investigated genetic variation in and associations between avoidance, resistance and tolerance in a natural host–parasite system. Replicated populations of Atlantic salmon ( Salmo salar ) and sea trout (an anadromous form of brown trout, Salmo trutta ) were raised under common garden conditions and infected with the eye fl…

0106 biological sciencesavoidancehost defenceEvolutionTroutSalmo salarPopulationZoologyparasitismiSalmonid fishBiologyTrade-off010603 evolutionary biology01 natural scienceseläinten käyttäytyminenGeneral Biochemistry Genetics and Molecular BiologyHost-Parasite InteractionsresistanceFish Diseases03 medical and health sciencespopulaatiotloisetGenetic variationisäntäeläimetAnimalsParasite hostingParasitesParasite Infections14. Life underwatereducation030304 developmental biologyGeneral Environmental Sciencetrade-offsietokyky0303 health scienceseducation.field_of_studytoleranceGeneral Immunology and MicrobiologyResistance (ecology)Host (biology)imumadotlohikalatGeneral Medicinetrematode parasitegeneettinen muunteluresistenssiTrematodaGeneral Agricultural and Biological Sciences
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Rapid induction of immune density-dependent prophylaxis in adult social insects.

2009

The innate immune system provides defence against parasites and pathogens. This defence comes at a cost, suggesting that immune function should exhibit plasticity in response to variation in environmental threats. Density-dependent prophylaxis (DDP) has been demonstrated mostly in phase-polyphenic insects, where larval group size determines levels of immune function in either adults or later larval instars. Social insects exhibit extreme sociality, but DDP has been suggested to be absent from these ecologically dominant taxa. Here we show that adult bumble-bee workers ( Bombus terrestris ) exhibit rapid plasticity in their immune function in response to social context. These results sugges…

0106 biological sciencesdensity-dependent prophylaxisZoology[ SDV.IMM.IA ] Life Sciences [q-bio]/Immunology/Adaptive immunology010603 evolutionary biology01 natural sciences03 medical and health sciencesImmune system[ SDV.EE.IEO ] Life Sciences [q-bio]/Ecology environment/SymbiosisAnimalsinnate immunitySociality030304 developmental biologyPopulation Density[ SDE.BE ] Environmental Sciences/Biodiversity and EcologyEvolutionary Biology0303 health sciencesLarvaInnate immune systembiologyEcologyfungiAge FactorsAdult insectBeessocialitybiology.organism_classificationAdaptation PhysiologicalAgricultural and Biological Sciences (miscellaneous)Immunity InnateBombus[SDV.IMM.IA]Life Sciences [q-bio]/Immunology/Adaptive immunologyDensity dependentBombus terrestrisInstar[SDE.BE]Environmental Sciences/Biodiversity and EcologyGeneral Agricultural and Biological Sciences[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/Symbiosis
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Is the impact of environmental noise visible in the dynamics of age-structured populations?

2001

Climate change has ignited lively research into its impact on various population–level processes. The research agenda in ecology says that some of the fluctuations in population size are accountable for by the external noise (e.g. weather) modulating the dynamics of populations. We obeyed the agenda by assuming population growth after a resource–limited Leslie matrix model in an age–structured population. The renewal process was disturbed by superimposing noise on the development of numbers in one or several age groups. We constructed models for iteroparous and semelparous breeders so that, for both categories, the population growth rate was matching. We analysed how the modulated populatio…

0106 biological scienceseducation.field_of_studyDisturbance (geology)General Immunology and MicrobiologyNoise (signal processing)010604 marine biology & hydrobiologyPopulation sizePopulationGeneral MedicineLeslie matrix010603 evolutionary biology01 natural sciencesGeneral Biochemistry Genetics and Molecular BiologyGeographyPopulation growthGeneral Agricultural and Biological SciencesEnvironmental noiseeducationSemelparity and iteroparityGeneral Environmental ScienceDemographyProceedings of the Royal Society of London. Series B: Biological Sciences
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Punishment of polygyny

1999

We investigated the evolution of monogamy (one male, one female) and polygyny (one male, more than one female). In particular, we studied whether it is possible for a mutant polygynous mating strategy to invade a resident population of monogamous breeders and, alternatively, whether a mutant monogamy can invade resident polygyny. Our population obeys discrete-time Ricker dynamics. The role of males and females in the breeding system is incorporated via the harmonic birth function. The results of the invasability analysis are straightforward. Polygyny is an evolutionarily stable strategy mating system; this holds throughout the examined range of numbers of offspring produced per female. So t…

0106 biological scienceseducation.field_of_studyGeneral Immunology and MicrobiologyOffspring010604 marine biology & hydrobiologyPopulationZoologyGeneral MedicineBiologyMating system010603 evolutionary biology01 natural sciencesPopulation densityArticleGeneral Biochemistry Genetics and Molecular BiologyEvolutionarily stable strategyBiological dispersalMatingGeneral Agricultural and Biological ScienceseducationPolygynyGeneral Environmental ScienceDemographyProceedings of the Royal Society of London. Series B: Biological Sciences
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The fungal elicitor cryptogein induces cell wall modifications on tobacco cell suspension

2000

Upon addition of the fungal elicitor cryptogein, suspension cells of tobacco (Nicotiana tabacum cv. Xanthi) aggregated in clusters. Cytochemical experiments indicated that elicited cells displayed fibrillar expansions of pectin along the primary cell wall. Immunocytochemical detection of pectin epitopes indicated that the fibrillar material surrounding the treated cells was mostly composed of low methylated galacturonan sequences, but the use of the cationic probe did not reveal the presence of negatively charged carboxyl groups: the presence of important amounts of calcium ions in these pectic fibrillar expansions accounts for these observations. These data indicate that tobacco cells trea…

0106 biological sciencesfood.ingredientPectinPhysiologyNicotiana tabacumchemistry.chemical_elementPlant ScienceCalcium01 natural sciences[SDV.BV.BOT] Life Sciences [q-bio]/Vegetal Biology/BotanicsCell wallFungal Proteins03 medical and health sciencesfoodCell WallTobaccoCells CulturedComputingMilieux_MISCELLANEOUS030304 developmental biology0303 health sciencesbiologyAlgal Proteins[SDV.BV.BOT]Life Sciences [q-bio]/Vegetal Biology/Botanicsbiology.organism_classificationImmunohistochemistryElicitorRespiratory burstMicroscopy ElectronPlants ToxicBiochemistrychemistryCell cultureBiophysicsCalciumSignal transduction010606 plant biology & botany
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