Search results for "usa"

The role of blood DNA methylation in environment-related chronic disease: a biostatistical toolkit

2013

La epigenética se refiere al estudio de las marcas químicas que alteran la expresión génica sin cambiar la secuencia genética. Los factores ambientales y conductuales son conocidos modificadores de la epigenética, resultando así en cambios heredables que pueden dar lugar a alteraciones en procesos biológicos esenciales y, por consiguiente, al desarrollo de enfermedades. La metilación del ADN es la marca epigenética más estudiada. Existe amplia evidencia científica de la asociación entre factores ambientales tales como tabaco y metales, y desregulaciones en la metilación del ADN. Asimismo, existe amplia evidencia de la asociación entre desregulaciones en metilación del ADN y enfermedades cró…

Comparative Molecular Evolution of Primary (Buchnera) and Secondary Symbionts of Aphids Based on Two Protein-Coding Genes

2001

A+T content, phylogenetic relationships, codon usage, evolutionary rates, and ratio of synonymous versus non-synonymous substitutions have been studied in partial sequences of the atpD and aroQ/pheA genes of primary ( Buchnera) and secondary symbionts of aphids and a set of selected non-symbiotic bacteria, belonging to the five subdivisions of the Proteobacteria. Compared to the homologous genes of the last group, both genes belonging to Buchnera behave in a similar way, showing a higher A+T content, forming a monophyletic group, a loss in codon bias, especially in third base position, an evolutionary acceleration and an increase in the number of non-synonymous substitutions, confirming pre…

Cloning and sequencing of the dnaK region of Streptomyces coelicolor A3(2)

1993

Abstract The dnaK homologue of Streptomyces coelicolor A3(2) strain M145 has been cloned and sequenced. Nucleotide sequence analysis of a 2.5-kb region revealed an open reading frame (ORF) encoding a predicted DnaK protein of 618 amino acids (Mr = 66 274). The dnaK coding sequence displays extreme codon bias and shows a strong preference for CGY and GGY, for Arg and Gly codons, respectively. The predicted DnaK sequence has a high Lys:Arg ratio which is not typical of streptomycete proteins. The region immediately downstream from dnaK contains an ORF for a GrpE-like protein; the predicted start codon of grpE overlaps the last two codons of dnaK, indicating that the two genes are translationa…

Bacteria and free-living amoeba in the Lascaux Cave.

2008

3 pages, 1 table, 18 references. The collaboration of the Lascaux restoration team is highly appreciated. We thank Marisa Chelius for valuable comments on the manuscript.

Phytochemical profile and bioactivity of traditional ayurvedic decoctions and hydro-alcoholic macerations of Boerhaavia diffusa L. and Curculigo orch…

2015

Decoctions (DECs) and hydro-alcoholic extracts (HEs) prepared from roots of Boerhaavia diffusa L. (Nyctaginaceae) and Curculigo orchioides Gaertn. (Hypoxidaceae) were phytochemically characterised by HPLC-DAD and profiled for their antioxidant, antigenotoxic and cytotoxic activities. B. diffusa DEC was rich in ferulic acid and vanillin, while the HE also contained boeravinone B and eupalitin. Both C. orchioides HE and DEC displayed the main occurrence of orcinol-β-d-glucoside and curculigoside A. Antioxidant activity was assayed through spectrophotometric DPPH, ABTS and β-carotene bleaching test, and using (HP)TLC bioautographic strategies. For both crude drugs, HE was the best performing p…

Towards a meta-method for the engineering of situational evaluation methods for domain-specific modeling tools

2015

Sovellusaluemallinnus (Domain-Specific Modeling, DSM) on eräs ohjelmistotuotannon lähestymistavoista, jossa sovelluskehityksen abstraktiotasoa nostetaan ohjelmoinnista sovellusaluekeskeiseen mallinnukseen. DSM mahdollistaa sovelluskehityksen automatisoinnin erityisesti kapeilla ja vakiintuneilla sovellusalueilla, joiden käsitteet, säännöt ja merkitykset soveltuvat DSM-kielten konstruktioiksi. DSM-välineet tarjoavat työkaluja DSM-kielten määrittelyyn ja käyttöön sekä sovellusmallien transformaatioihin. Teollisuudessa DSM-välineiden arviointeja tehdään tyypillisesti välinehankintojen valmistelun yhteydessä. Arviointeja suoritetaan myös tieteellisen tutkimuksen näkökulmasta. Arviointitulosten …

Latvijas Universitātes Bibliotēkas jaunumi, 2015

2015

Emotion-driven encoding of music preference and personality in dance

2014

Thirty rhythmic music excerpts were presented to 60 individuals. Dance movements to each excerpt were recorded using an optical motion-capture system, preference for each excerpt recorded on a 5-point Likert scale, and personality assessed using the 44-item version of the Big Five Inventory. From the movement data, a large number of postural, kinematic and kinetic features were extracted, a subset of which were chosen for further analysis using sequential backward elimination with variance inflation factor (VIF) selection. Multivariate analyses revealed significant effects on these 11 features of both preference and personality, as well as a number of interactions between the two. As regar…

A Distributed approach to the Remote Control and Programming Improvement

2006

The remote control of industrial plants through networks is becoming very important nowadays but it involves several issues that can degrade the performance and usability of the remote plant. This paper presents a distributed architecture improving a remote programming system which allows users to control and to program a plant remotely. The control system is based on a client/server architecture with many user interfaces that control the plant. The remote programming language is a mix of Java and client/server protocol in order to simplify the developing and to avoid the protocol/language translation. In order to obtain more efficiency, the program is developed in the client side and it is…

Reusability and modularity in transactional workflows

1997

Abstract Workflow management techniques have become an intensive area of research in information systems. In large scale workflow systems modularity and reusability of existing task structures with context dependent (parameterized) task execution are essential components of a successful application. In this paper we study the issues related to management of modular transactional workflows, i.e., workflows that reuse component tasks and thus avoid redundancy in design. The notion of parameterized transactional properties of workflow tasks is introduced and analyzed, and the underlying architectural issues are discussed.