Search results for "utero"

Valutazione dell'attività dell'asse ipotalamo-ipofisi-surrene, in seguito all'esposizione in utero a stress acuto e cronico nella progenie di ratto a…

2011

Non-cell autonomous and non-catalytic activities of ATX in the developing brain

2015

The intricate formation of the cerebral cortex requires a well-coordinated series of events, which are regulated at the level of cell-autonomous and non-cell autonomous mechanisms. Whereas cell-autonomous mechanisms that regulate cortical development are well-studied, the non cell-autonomous mechanisms remain poorly understood. A non-biased screen allowed us to identify Autotaxin (ATX) as a non cell-autonomous regulator of neural stem cell proliferation. ATX (also known as ENPP2) is best known to catalyze lysophosphatidic acid (LPA) production. Our results demonstrate that ATX affects the localization and adhesion of neuronal progenitors in a cell autonomous and non-cell autonomous manner, …

Safety of combined bambuterol and theophylline as a potential treatment of high altitude‐induced fatigue in humans

2016

Biomarkers in obstructive respiratory diseases: An update

2012

Chronic obstructive pulmonary disease (COPD) is characterized by chronic inflammation of the airways, with the involvement of many inflammatory cells and mediators. Traditionally, this inflammation is thought to spread to a systemic level, thus inducing damage of different organs. However, other pathogenetic mechanisms could take part to the above-described process, and some open questions need to be solved. Due to the burden and increasing prevalence of COPD, the opportunity to find biomarkers that can potentially be useful in identifying individuals with the disease, or better, prior to symptoms onset, to diagnose and properly manage the respiratory symptoms, as well as to evaluate the re…

High Current Proton and Deuteron Beams for Accelerators and Neutron Generators

2014

This paper presents the latest results of high current proton and deuteron beam production at SMIS 37 facility at the Institute of Applied Physics (IAP RAS). In this experimental setup the plasma is created and the electrons are heated by 37.5 GHz gyrotron radiation with power up to 100 kW in a simple mirror trap fulfilling the ECR condition. High microwave power and frequency allow sustaining higher density hydrogen plasma (ne up to 2·1013 cm-3) in comparison to conventional ECRIS’s or microwave sources. The low ion temperature, on the order of a few eV, is beneficial to produce proton beams with low emittance. Latest experiments at SMIS 37 were performed using a single-aperture two-electr…

First real–time detection of solar pp neutrinos by Borexino

2014

International audience; Solar neutrinos have been pivotal to the discovery of neutrino flavour oscillations and are a unique tool to probe the reactions that keep the Sun shine. Although most of solar neutrino components have been directly measured, the neutrinos emitted by the keystone pp reaction, in which two protons fuse to make a deuteron, have so far eluded direct detection. The Borexino experiment, an ultra-pure liquid scintillator detector running at the Laboratori Nazionali del Gran Sasso in Italy, has now filled the gap, providing the first direct real time measurement of pp neutrinos and of the solar neutrino luminosity.

Single π0 production off neutrons bound in deuteron with linearly polarized photons

2021

The quasifree γ→d→π0n(p) photon beam asymmetry, Σ, has been measured at photon energies, Eγ, from 390 to 610 MeV, corresponding to center of mass energy from 1.271 to 1.424 GeV, for the first time. The data were collected in the A2 hall of the MAMI electron beam facility with the Crystal Ball and TAPS calorimeters covering pion center-of-mass angles from 49∘ to 148∘. In this kinematic region, polarization observables are sensitive to contributions from the Δ(1232) and N(1440) resonances. The extracted values of Σ have been compared to predictions based on partial-wave analyses (PWAs) of the existing pion photoproduction database. Our comparison includes the SAID, MAID and Bonn–Gatchina anal…

Measurement of the spin-dependent structure function g1(x) of the deuteron

1993

We report on the first measurement of the spin-dependent structure function g1d of the deuteron in the deep inelastic scattering of polarised muons off polarised deuterons, in the kinematical range 0.006<x<0.6, 1 GeV2<Q2<30 GeV2. The first moment, Γ1d=sh{phonetic}01 g1d dx=0.023±0.020 (stat.) ± 0.015 (syst.), is smaller than the prediction of the Ellis-Jaffe sum rules. Using earlier measurements of g1p, we infer the first moment of the spin-dependent neutron structure function g1n. The difference Γ1p-Γ1n=0.20 ±0.05 (stat.) ± 0.04 (syst.) agrees with the prediction of the Bjorken sum rule, Γ1p-Γ1n=0.191 ±0.002.

La riflessività nel percorso formativo dei formatori

2012

Transverse momentum distributions for exclusive $\varrho^{0}$ muoproduction

1992

We have studied transverse momentum distributions for exclusive rho(0) muoproduction on protons and heavier nuclei at 2 < Q2 < 25 GeV2. The Q2 dependence of the slopes of the p(t)2 and t' distributions is discussed. The influence of the non-exclusive background is investigated. The p(t)2-slope for exclusive events is 4.3 +/- 0.6 +/- 0.7 GeV-2 at large Q2. The p(t)2 spectra are much softer than inclusive p(t)2 spectra of leading hadrons produced in deep inelastic scattering.