Search results for "very"

An integrated approach to process analysis in a public administration: Business Process Reengineering and System Dynamics to support the funds delive…

2011

COVID-19 Lessons and Post-pandemic Recovery: A Case of Latvia.

2022

The research was supported by the NATIONAL RESEARCH PROGRAMME “LATVIAN HERITAGE AND FUTURE CHALLENGES FOR THE SUSTAINABILITY OF THE STATE” project “CHALLENGES FOR THE LATVIAN STATE AND SOCIETY AND THE SOLUTIONS IN INTERNATIONAL CONTEXT" (INTERFRAME-LV, Project No.VPP-IZM-2018/1-0005).

Returns To Education During And After The Economic Crisis: Evidence From Latvia 2006–2012

2017

We employ EU-SILC micro data for Latvia to study how returns to education changed during the economic crisis of 2008–2009 and afterwards. We found that returns to education increased significantly during the crisis and decreased slightly during the subsequent economic recovery. The counter-cyclical effect was evident in nearly all population groups. After the crisis, education became more associated than before with a longer working week and a higher employment probability. Furthermore, we show that returns to education in Latvia are generally higher in the capital city and its suburbs than outside the capital city region, as well as for citizens of Latvia than for resident non-citizens and…

COLLOIDAL VECTORS WITH POLYAMINOACID STRUCTURE FOR ORAL RELEASE OF PEPTIDES AND PROTEINS AND METHOD FOR THEIR PRODUCTION

2008

The present invention concerns colloidal vectors with polyaminoacid structure for oral release of peptides and proteins and a method for their production. Specifically, the invention concerns systems for the release of active substances, specifically peptides and proteins, by means of their incorporation in nanoparticles, nano-aggregates or complexes based on properly derivatized synthetic polyaminoacids. These polymeric systems are proposed to release peptide drugs or proteins from oral dosage forms in an effective manner, besides increasing the physicochemical stability of proteins in liquid or solid pharmaceutical dosage forms.

Proteomics in antitumor research

2006

Proteins are the molecular players of fine-tuned regulatory pathways that underlie the behavior of any cell type. Derangement of this wide protein circuitry has a profound effect on cell life and ultimately contributes to the development of diseases such as cancer. New proteomic technologies are rapidly evolving to define and characterize the nodes of this altered protein network, both inside and outside cancer cells. Hopefully, these technologies will become user-friendly laboratory tools to improve cancer management from early detection to the development of rational and patient-tailored therapeutic strategies.

Women's Place in Finnish Proverbs from Childhood

2010

The purpose of this article is to introduce some features of the relationship between proverbs and gender in Finnish folklore tradition. I focus on pedagogical speech using proverbs in the life-stories from the end of the 19th century and the beginning of the 20th century. The main interest is on bringing up children concentrating on the written memories and the everyday life of ordinary people. This deals with the private level of education in childhood memories.

Scheduling under the network of temporo-spatial proximity relationships

2017

We discuss and introduce to the schedulingeld a novel, qualitative optimization model - scheduling under the network of temporo-spatial proximity relationships.We introduce a half perimeter proximity measure as an objective of scheduling.We present and evaluate an incremental Sequence Pair neighborhood evaluation algorithm, applicable to both scheduling and rectangle packing problems in VLSI industry. In this paper, we discuss and introduce to the scheduling field a novel optimization objective - half perimeter proximity measure in scheduling under the network of temporo-spatial proximity relationships. The presented approach enables to qualitatively express various reasons of scheduling ce…

L'abbé Grégoire, son legs : six concours pour la liberté et l'égalité

2000

Gregoire's last will and testament called for the organization of six awards to be granted on the basis of written competitions on subjects that included reflections upon despotism, slavery, liberties, and equality, the themes of the struggles that had engaged Gregoire. Although the quality of the essays that resulted were not up to the level that the abbot had no doubt hoped for, the competition relative to the means of fighting the prejudice of color was the occasion to open a large debate and to launch the French abolitionist movement.

Spouses’ Experiences of Rehabilitees’ Burnout and Recovery

2021

The role of family members’ support in the burnout recovery process has been recognized in several studies. The role of emotional support provided by the spouse has been found to be significant in reducing burnout levels. Although crossover of burnout and emotional support have been investigated, the partners’ experiences of the individuals’ burnout and recovery have remained largely unexplored. To fill this research gap the study aims to provide in-depth knowledge of the experiences of spouses of individuals who have a history of burnout and are recovering from it by participating in a rehabilitation course. Ten spouses of individuals who had previously suffered and had recovered or was re…

Fighting Antibiotic Resistance: New Pyrimidine-Clubbed Benzimidazole Derivatives as Potential DHFR Inhibitors

2023

The present work describes the design and development of seventeen pyrimidine-clubbed benzimidazole derivatives as potential dihydrofolate reductase (DHFR) inhibitors. These compounds were filtered by using ADMET, drug-likeness characteristics calculations, and molecular docking experiments. Compounds 27, 29, 30, 33, 37, 38, and 41 were chosen for the synthesis based on the results of the in silico screening. Each of the synthesized compounds was tested for its in vitro antibacterial and antifungal activities using a variety of strains. All the compounds showed antibacterial properties against Gram-positive bacteria (Staphylococcus aureus and Staphylococcus pyogenes) as well as Gram-negativ…