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showing 10 items of 6927 documents
Working hours – tracking the current and future trends
2021
It is important to track the trends of future working hours, since working hours have strong associations to everyday life and work-life interaction, but also to health. In this paper we aim to track the current and future trends in working hours. We discuss the trends through the key dimensions of working hours: the length, timing, tempo and autonomy. We also consider the role of current trends of spatial changes of work. Changes in working time patterns are fostered by several driving factors: globalization and business restructuring challenging the current work organizations, new information technologies, demographic and climate change and the current and future pandemics. The past and c…
Dipeptidyl Enoates As Potent Rhodesain Inhibitors That Display a Dual Mode of Action
2015
Dipeptidyl enoates were prepared through a high-yielding two-step synthetic route. They have a dipeptidic structure with a 4-oxoenoate moiety as a warhead with multiple reactive sites. Dipeptidyl enoates were screened against rhodesain and human cathepsins B and L, and were found to be potent and selective inhibitors of rhodesain. Among them (S,E)-ethyl 5-((S)-2-{[(benzyloxy)carbonyl]amino}-3-phenylpropanamido)-7-methyl-4-oxooct-2-enoate (6) was the most potent, with an IC50 value of 16.4 nm and kinact/Ki=1.6×106 m−1 s−1 against rhodesain. These dipeptidyl enoates display a reversible mode of inhibition at very low concentrations and an irreversible mode at higher concentrations. Inhibition…
Estetica urbana. Atmosfere e artificazione degli spazi della città
2023
Ancora uno studio su questo argomento, infatti i pochi saggi su temi analoghi non adottano una prospettiva filosofica. Il volume mira a colmare questa lacuna affrontando l’estetica urbana attraverso due paradigmi interpretativi, che talvolta nel libro vengono intrecciati: i concetti di atmosfera e di artificazione. La nozione di “atmosfera” nasce in seno alla nuova fenomenologia tedesca di Hermann Schmitz ed è declinata verso l’estetica dal filosofo Gernot Böhme che la considera un paradigma privilegiato per indagare gli spazi emozionali, intesi come frutto di relazioni affettive tra il soggetto percipiente e l’oggetto percepito. Pertanto l’estetica delle atmosfere si rivela uno strumento t…
Cultural heritage through history and nature: conservation and re-use. The Scicli case study
2013
The research originates from a relationship between a local body of illustrious traditions and a research facility of the University of Palermo – the Interdepartmental Research Centre on Historical Centres (hereafter C.I.R.CE.S.), that has the aim of providing consultancy and scientific support to the initiatives of territorial bodies concerning policies and urban and territorial redevelopment plans and the redevelopment of historical centres. Scicli is one of the most important towns belonging to the province of Ragusa. The urban centre, in addition to being able to boast a special identity deriving from the peculiar impact of the dazzling baroque architectures on the surrounding landscap…
Dual Enzyme-Triggered Controlled Release on Capped Nanometric Silica Mesoporous Supports
2012
The development of nanoscopic hybrid materials equipped with “molecular gates” showing the ability of releasing target entrapped guests upon the application of an external trigger has attracted great attention and has been extensively explored during recent years.1 These nanodevices are composed of two subunits, namely, a suitable support and certain capping entities grafted on the surface of the scaffolding.2 The support is used as a suitable reservoir in which certain chemicals can be stored whereas the molecules grafted in the outer surface act as a “gate” and can control the release of the entrapped molecules at will. Both components are carefully selected and arranged in order to achie…
The effects on riding performance using active vs passive recovery during a simulated motocross race
2017
Aleix Ollé Casanovas. 2017. The effects on riding performance using active vs passive recovery during a simulated motocross race. University of Jyväskylä. 53p. The aim of the present study was to examine the effect of active and passive recovery methods in order to improve physical performance between motocross races. Exercise induced muscle damage post motocross racing was assessed as well. Participants performed 2 races of 30 minutes with one hour break in between. During the break they performed either active or passive recovery protocols. Specific motocross performance outcomes and athlete’s physical conditions were measured during, and before and after every motocross race. Lap times (…
Restitusjonsvaner hos unge toppidrettsutøvere i Sør-Norge : En kartleggingsstudie av utholdenhet- og ballspillutøvere
2018
Masteroppgave idrettsvitenskap ME517 - Universitetet i Agder 2018 Background: In order to perform optimally in training and competition, the recovery inbetween, through adequate diet and sufficient sleep/rest, is of great importance. Up until now, most studies have only featured adult athletes. Similarly, studies conducted on young athletes, as well as across sports, are limited. Purpose: The purpose of this study was to assess the habits of recovery, in terms of diet and sleep, with regards to the recommendations given by Helsedirektoratet and Olympiatoppen. Further investigating the use of different recovery strategies, among young elite athletes in southern Norway. Method: A total of 36 …
The Role of Existential Concerns in the Individual’s Decisions regarding COVID-19 Vaccine Uptake: A Survey among Non-Vaccinated Italian Adults during…
2022
Recent studies have suggested that health constructs embraced by the Terror Management Theory (TMT) and the Basic Psychological Needs Theory (BPNT) may drive individuals’ COVID-19 health-related decisions. This study examines the relationships between existential concerns (ECs; within the TMT), basic psychological needs (BPNs; within the BPNT) and COVID-19 vaccine hesitancy (VH), as well as the mediating role of negative attitudes toward COVID-19 vaccines. A cross-sectional survey was carried out from April to May 2021 on a sample of two hundred and eighty-seven adults (Mage = 36.04 ± 12.07; 59.9% females). Participants provided information regarding existential concerns, basic psychologica…
SST Comparison of AVHRR and MODIS Time Series in the Western Mediterranean Sea
2020
La temperatura de la superficie del mar (SST) es un parámetro clave para comprender los procesos atmosféricos y oceánicos. Desde finales de la década de 1980, las imágenes de satélite infrarrojas se han utilizado para complementar los registros in situ para estudiar la variabilidad temporal y espacial de la SST. El radiómetro avanzado de muy alta resolución (AVHRR) del satélite de la Administración Nacional Oceánica y Atmosférica (NOAA) fue el primer sensor utilizado con éxito para calcular la SST después del desarrollo y validación del algoritmo de corrección atmosférica conocido como 'ventana dividida'. Más recientemente, el espectrorradiómetro de imágenes de resolución MODERADA (MODIS) a…
Comparison of inter-trial recovery times for the determination of critical power and W' in cycling
2017
Critical Power (CP) and W’ are often determined using multi-day testing protocols. To investigate this cumbersome testing method, the purpose of this study was to compare the differences between the conventional use of a 24-h inter-trial recovery time with those of 3 h and 30 min for the determination of CP and W’. Methods: 9 moderately trained cyclists performed an incremental test to exhaustion to establish the power output associated with the maximum oxygen uptake (p V O2max), and 3 protocols requiring time-to-exhaustion trials at a constant work-rate performed at 80%, 100% and 105% of p VO2max. Design: Protocol A utilised 24-h inter-trial recovery (CP24/W’24), protocol B utilised 3-h in…