Search results for "virus"

Regulación de la tasa de mutación en virus de DNA

2019

Los virus de DNA son extremadamente abundantes en todos los ecosistemas pero tradicionalmente se ha pensado que su grado de diversidad genética y adaptabilidad es mucho menor que el de los virus de RNA al presentar tasas de mutación inferiores. La tasa de mutación de algunos virus de DNA puede llegar a ser mil veces superior que la de su hospedador, incluso cuando el virus utiliza la polimerasa de la célula huésped para la replicación. A pesar de ello, existe muy poca información sobre las tasas de mutación de los virus de DNA. Es muy probable que una de las razones sea que las tecnologías de secuenciación de nueva generación (NGS), en muchos casos, presentan tasas de error que son órdenes …

Emergenza coronavirus e prelievo fiscale, tra diritti “scontati”, obbligo contributivo, solidarietà ed Europa: riflessioni a caldo

2020

Esiste un legame fra la solidarietà indotta dalla pandemia da coronavirus e il relativo principio che informa l’obbligo contributivo nel nostro assetto costituzionale? Esiste un legame fra la solidarietà che sta alla base dell’obbligo contributivo, il diritto alla salute ed i diritti fondamentali in generale? Quanto pesa sull’adempimento d’imposta la motivazione che ne sta a fondamento e la possibilità di imprimere una destinazione ad esso? Che tipo di solidarietà dobbiamo attenderci dall’Europa? Il presente scritto fornisce riflessioni mini me nel tentativo di rispondere a tali interrogativi. Does it exist a link between solidarity pushed up by coronavirus pandemic and the basic solidarity…

New insight into the interplay of baculovirus and subnuclear structures in HepG2 cells

2007

Kadonneeksi luultu virustyyppi löytyi ikääntyvien B-soluista

2017

Commonalities between ENT Specialists and Oral Medicine Experts: Old HPV Diseases and New Oral HPV-Cancer along the Borders

2021

A human papillomavirus (HPV) infection is globally one of the most common causes of sexually transmitted infections of the mucous membranes (genital, anal and oral). Over the last decade, an increasing number of young patients have been infected due to the changes in sexual habits in the general population. The majority of the lesions are benign; however, substantial scientific evidence has suggested a role for the HPV family in the carcinogenesis of squamous cell carcinoma (SCC). It is proposed that dentists, in addition to ENT specialists, should apply standardized management protocols in order to construct a well-defined pathway in terms of diagnosis, which is based on a PCR diagnostic t…

Internalization of novel non-viral vector TAT-streptavidin into human cells

2007

Background. The cell-penetrating peptide derived from the Human immunodeficiency virus-1 transactivator protein Tat possesses the capacity to promote the effective uptake of various cargo molecules across the plasma membrane in vitro and in vivo. The objective of this study was to characterize the uptake and delivery mechanisms of a novel streptavidin fusion construct, TAT47–57-streptavidin (TAT-SA, 60 kD). SA represents a potentially useful TAT-fusion partner due to its ability to perform as a versatile intracellular delivery vector for a wide array of biotinylated molecules or cargoes. Results. By confocal and immunoelectron microscopy the majority of internalized TAT-SA was shown to accu…

Pre-sleep arousal and sleep quality during the COVID-19 lockdown in Italy

2021

Abstract Objective The COVID-19 pandemic has strongly affected daily habits and psychological wellbeing, and many studies point to large modifications in several sleep and sleep-related domains. Nevertheless, pre-sleep arousal during the pandemic has been substantially overlooked. Since hyperarousal represents one of the main factors for the development and the perpetuation of chronic insomnia disorder, the assessment of variables associated with high levels of pre-sleep arousal during the pandemic is clinically relevant. The study aimed to assess the prevalence and predictors of perceived sleep quality and pre-sleep arousal in an Italian sample during the COVID-19 lockdown. Methods We used…

Nurses’ strategies for dealing with stress during the COVID-19 pandemic

2021

Background: In view of the SARS-CoV-2 coronavirus pandemic, it is important to study the activities undertaken by nurses to cope with stress. Aim of the study: The study’s main objective was to analyze strategies of coping with stress among nurses working in public and non-public medical institutions in Opolskie and Lubelskie provinces, Poland, during the COVID-19 pandemic. Material and methods: The study group included a total of 155 nurses. The Mini-COPE questionnaire and the author’s original questionnaire were used in the study. Results: With increasing age, nurses coped with stress by using their sense of humor less often, seeking instrumental support, discharge of emotions, using psyc…

Child Well-Being in Times of Confinement: The Impact of Dialogic Literary Gatherings Transferred to Homes

2020

The COVID-19 pandemic has created an unexpected situation that has forced people to find educational alternatives to support learning and ensure child well-being. The need for practices that 'open doors' at home as a way to promote a quality education and to foster an environment of supportive relationships and a sense of community, has led to the in-depth analysis of successful educational actions, particularly the Dialogic Literary Gatherings (DLGs). The aim of this article is to show how the transference of DLGs to the home environment has had an impact on child subjective well-being in times of confinement, promoting a safe and supportive environment for learning, interacting, coexistin…

Initial-Stage Suicide Bereavement Experiences: A Case Study.

2022

This study aimed to shed light on the initial-stage bereavement experiences of an individual bereaved by suicide, at three months from the loss of his spouse to suicide. A semi-structured in-depth interview was conducted with the individual, a man in his thirties. The data were analyzed using qualitative assimilation analysis, based on the Assimilation Model and the Assimilation of Problematic Experiences Scale (APES). The APES ratings of the interview revealed that the individual’s bereavement was associated with the earlier stages of APES (all scoring under 3.5). In addition, the swift and frequent fluctuations in the APES ratings gave indications that the bereavement was unstable and co…