Search results for "word"

showing 10 items of 1504 documents

Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging

2021

Abstract Background Biological aging estimators derived from DNA methylation data are heritable and correlate with morbidity and mortality. Consequently, identification of genetic and environmental contributors to the variation in these measures in populations has become a major goal in the field. Results Leveraging DNA methylation and SNP data from more than 40,000 individuals, we identify 137 genome-wide significant loci, of which 113 are novel, from genome-wide association study (GWAS) meta-analyses of four epigenetic clocks and epigenetic surrogate markers for granulocyte proportions and plasminogen activator inhibitor 1 levels, respectively. We find evidence for shared genetic loci ass…

AgingMultifactorial InheritanceBLOODEpigenetic clock05 Environmental SciencesbiomarkkeritGenome-wide association studyQH426-470Epigenesis Genetic/dk/atira/pure/core/keywords/icep0302 clinical medicineBiomarkers of agingGWASBiology (General)AdiposityGenetics11832 Microbiology and virology0303 health sciences318 Medical biotechnologyDNA methylation1184 Genetics developmental biology physiologygenomiikkaDna Methylation ; Epigenetic Clock ; Gwasddc:DNA-metylaatioINSIGHTSC-Reactive ProteinepigenetiikkaDNA methylationMENDELIAN RANDOMIZATION/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingEducational StatusICEPGenetic MarkersPROVIDESSUSCEPTIBILITY LOCIBioinformaticsQH301-705.5GenomicsBiology03 medical and health sciencesNHLBI Trans-Omics for Precision Medicine (TOPMed) ConsortiumAGESDG 3 - Good Health and Well-beingPlasminogen Activator Inhibitor 1REGRESSIONGeneticsHumansEpigeneticsGeneMETAANALYSIS030304 developmental biologyGenome HumanResearchGenetics of DNA Methylation Consortium06 Biological SciencesLipid MetabolismHuman geneticsGenetic architectureImmunity InnateikääntyminenGenetic LociCpG Islands08 Information and Computing Sciences3111 BiomedicineENRICHMENTepigenetic clock030217 neurology & neurosurgeryBiomarkersGenome-Wide Association StudyGranulocytes
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Contribution of the physical, social, psychological and environmental domains to overall quality of life of the elderly

2006

Este estudo investigou a contribuição de cada domínio da qualidade de vida (físico, social, psicológico e ambiental) na qualidade de vida global e em que extensão esses domínios explicam a qualidade de vida global de idosos residentes no município de Teixeiras, na Região Sudeste do Brasil. Trata-se de um estudo observacional de corte transversal, sendo a amostragem aleatória estratificada por sexo, uso do Programa Saúde da Família e microárea de saúde (n = 211, indivíduos com idade igual ou superior a 60 anos), representando 14,28% do total de idosos do município em estudo. O instrumento utilizado foi o Word Health Organization Quality of Life Instrument Bref (WHOQOL-Bref), proposto pela Or…

AgingWhoqol brefEnvelhecimentoElderly people’s healthEnvejecimientoWHOQOL-BrefPsychiatry and Mental healthquality of lifequalidade de vidasalud del mayorcalidad de vidaWord Health Organization Quality of Life Instrument Brefelderly people's healthsaúde do idosoPsychologyHumanitiesRevista de Psiquiatria do Rio Grande do Sul
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Humane Orientation as a New Cultural Dimension of the GLOBE Project: A Validation Study of the GLOBE Scale and Out-Group Humane Orientation in 25 Cou…

2013

SCHLÖSSER, Oliver; HEINTZE, Anna-Maria; AL-NAJJAR, Musaed; ARCISZEWSKI, Thomas; BESEVEGIS, Elias; BISHOP, George David; BONNES, Mirilia; CLEGG, Chris W.; DROZDA-SENKOWSKA, Ewa; GABORIT, Mauricio; GARZON, Dayra; HANSEN, Tia G. B.; HESZEN, Irena; JUHASZ, Marta; KEATING, Mary A.; MANGUNDJAYA, Wustari; MANSOR, Norma; MITCHELSON, Jacqueline K.; ORTIZ-REYNOSO, Alejandra; PANDEY, Janak; PAVAKANUN, Ubolwanna; PAVLOPOULOS, Vassilis; PEIRO, Jose M.; POTOCNIK, Kristina; RESTREPO-ESPINOSA, Maria H.; SEMMER, Norbert; TUPINAMBA, Antonio Caubi Ribeiro; VENTURA, Elizabeth R.; WHOOLERY, Matthew; ZHANG, Kan. Humane orientation as a new cultural dimension of the globe project: a validation study of the globe …

Agreeableness/dk/atira/pure/core/keywords/549207066Cultural StudiesSocial PsychologyAgreeablenessGlobe/dk/atira/pure/subjectarea/asjc/3300/3316AuthoritarianismReligiositymedicine/dk/atira/pure/subjectarea/asjc/3300/3314Hofstede's cultural dimensions theoryBusiness psychology/dk/atira/pure/core/keywords/entrepreneurshipConstruct validationReligiosity/dk/atira/pure/subjectarea/asjc/3200/3207AuthoritarianismGlobal LeadershipEntrepreneurshipIngroups and outgroupsmedicine.anatomical_structureOrganizational behaviorAnthropologyPsychologySocial psychologyWelfare state
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Additivity of affine designs

2020

We show that any affine block design $$\mathcal{D}=(\mathcal{P},\mathcal{B})$$ is a subset of a suitable commutative group $${\mathfrak {G}}_\mathcal{D},$$ with the property that a k-subset of $$\mathcal{P}$$ is a block of $$\mathcal{D}$$ if and only if its k elements sum up to zero. As a consequence, the group of automorphisms of any affine design $$\mathcal{D}$$ is the group of automorphisms of $${\mathfrak {G}}_\mathcal{D}$$ that leave $$\mathcal P$$ invariant. Whenever k is a prime p,  $${\mathfrak {G}}_\mathcal{D}$$ is an elementary abelian p-group.

Algebra and Number Theory010102 general mathematics0102 computer and information sciencesAutomorphism01 natural sciencesCombinatoricsKeywords Affine block designs · Hadamard designs · Additive designs · Mathieu group M11010201 computation theory & mathematicsSettore MAT/05 - Analisi MatematicaAdditive functionDiscrete Mathematics and CombinatoricsAffine transformationSettore MAT/03 - Geometria0101 mathematicsInvariant (mathematics)Abelian groupMathematics
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On Combinatorial Generation of Prefix Normal Words

2014

A prefix normal word is a binary word with the property that no substring has more 1s than the prefix of the same length. This class of words is important in the context of binary jumbled pattern matching. In this paper we present an efficient algorithm for exhaustively listing the prefix normal words with a fixed length. The algorithm is based on the fact that the language of prefix normal words is a bubble language, a class of binary languages with the property that, for any word w in the language, exchanging the first occurrence of 01 by 10 in w results in another word in the language. We prove that each prefix normal word is produced in O(n) amortized time, and conjecture, based on expe…

Amortized analysisConjecturePrefix Normal WordBinary numbercombinatorial generation; formal languages; prefix normal words; binary strings; jumbled pattern matching; bubble languages; efficient algorithmsContext (language use)prefix normal wordsData_CODINGANDINFORMATIONTHEORYformal languagesbubble languagesSubstringcombinatorial generationbinary stringsPrefixCombinatoricsjumbled pattern matchingefficient algorithmsPattern matchingAlgorithmsWord (computer architecture)Mathematics
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Analogical reasoning and aging: the processing speed and inhibition hypothesis.

2014

This study was designed to investigate the effect of aging on analogical reasoning by manipulating the strength of semantic association (LowAssoc or HighAssoc) and the number of distracters' semantic analogies of the A:B::C:D type and to determine which factors might be responsible for the age-related differences on analogical reasoning by testing two different theoretical frameworks: the inhibition hypothesis and the speed mediation hypothesis. We compared young adults and two groups of aging people (old and old-old) with word analogies of the A:B::C:D format. Results indicate an age-related effect on analogical reasoning, this effect being greatest with LowAssoc analogies. It was not asso…

Analogical reasoningAdultMaleMediation (statistics)AgingInjury controlAccident preventionAnalogyPoison controlWord Association TestsExperimental and Cognitive PsychologySemantic associationDevelopmental psychologyYoung AdultReaction TimeHumansProblem SolvingAgedAged 80 and overMiddle AgedSemanticsPsychiatry and Mental healthNeuropsychology and Physiological PsychologyFemaleGeriatrics and GerontologyPsychologyPsychomotor PerformanceCognitive psychologyNeuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition
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A CORPUS-BASED APPROACH TO ANGLICISMS IN THE ROMANIAN ECONOMIC PRESS

2011

The paper conducts a quantitative analysis into the phenomenon of English borrowing in Romanian, as reflected in one of the leading economic publications over a period of one year (Capital 2005). Starting from a definition of Anglicisms that is based mainly on formal criteria, borrowed words in the above newspaper are identified and classified according to frequency of occurrence, both in relative and in absolute terms. Thus, Anglicism types and tokens are quantified as regards the proportion they hold in the total number of words in the publication, and in terms of their repetition rate. Special attention is devoted to borrowed words in the lowest and highest frequency ranges, with some of…

Anglicism borrowing word type word tokenStudies in Business and Economics
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Sturmian words and overexponential codimension growth

2018

Abstract Let A be a non necessarily associative algebra over a field of characteristic zero satisfying a non-trivial polynomial identity. If A is a finite dimensional algebra or an associative algebra, it is known that the sequence c n ( A ) , n = 1 , 2 , … , of codimensions of A is exponentially bounded. If A is an infinite dimensional non associative algebra such sequence can have overexponential growth. Such phenomenon is present also in the case of Lie or Jordan algebras. In all known examples the smallest overexponential growth of c n ( A ) is ( n ! ) 1 2 . Here we construct a family of algebras whose codimension sequence grows like ( n ! ) α , for any real number α with 0 α 1 .

Applied Mathematics010102 general mathematicsNon-associative algebraSturmian word01 natural sciences010101 applied mathematicsFiltered algebraCombinatoricsBounded functionAssociative algebraDivision algebraAlgebra representationComposition algebra0101 mathematicsMathematicsAdvances in Applied Mathematics
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Mosaic floors of roman Villa del Casale: Principal component analysis on spectrophotometric and colorimetric data

2013

Abstract Spectrophotometric and colorimetric data obtained during a measurement campaign aimed at supporting the Roman "Villa del Casale" (Piazza Armerina, Sicily, Italy) conservation activities, are presented. Special attention was paid to the possible variation of the chromatic coordinates, possibly due to the interventions of cleaning, consolidation, and protection. Data have been analyzed by the Principal Component Analysis (PCA) statistical technique, with the attempt to investigate its role in data variability reduction and verify its effectiveness in interpreting the phenomena occurring on the mosaic surface of the Villa, through grouping the observations into homogenous clusters. Ef…

ArcheologyData variabilityComputer scienceMaterials Science (miscellaneous)Spectrophotometric dataConservationAuthor keywords Colorimetric dataPrincipal Component AnalysiTreatment monitoringColor measurementChromatic scaleCluster analysisSpectroscopyVilla del Casalebusiness.industryData interpretationPattern recognitionArchaeologySettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)Chemistry (miscellaneous)Principal component analysisMosaic floorArtificial intelligencebusinessGeneral Economics Econometrics and FinanceTreatment monitoring
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The Protohistoric sword from Le Gué-de-Velluire (Vendée, France): a pasticcio's history unveiled by archaeometrical research

2020

International audience; The Gué-de-Velluire sword (Vendée, France) is part of the Rochebrune collection collected during the 19 th and the 20 th centuries and now preserved in the Dobrée Museum in Nantes (Loire-Atlantique, France). The unusual shape of its hilt, its uncorroded rivets and the rather uncommon combination of a bronze grip with an iron blade made this sword an exceptional object. It has been depicted in a large number of papers since the 20 th century, but the question of its authenticity has hardly ever been tackled. New analyses performed with the support of the Dobrée Museum, the Arc'Antique laboratory and Ghent University delivered new data enabling us to discuss this delic…

ArcheologyHistorySword[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and Prehistory0211 other engineering and technologiesArt historyComputed tomography02 engineering and technologyengineering.materialX-Ray Fluorescence spectroscopy01 natural sciencesTOMOGRAPHYmedicineBRONZE-AGEBronzeSWORDComputed tomography021101 geological & geomatics engineeringmedicine.diagnostic_testHistory and Archaeology010401 analytical chemistryPasticcioX-Ray Fluorescence Spectroscopy0104 chemical sciencesengineeringBlade (archaeology)Protohistory
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