Search results for "yo"

The pain threshold of high-threshold mechanosensitive receptors subsequent to maximal eccentric exercise is a potential marker in the prediction of D…

2017

Background Delayed-onset muscle soreness (DOMS) refers to dull pain and discomfort in people after participating in exercise, sport or recreational physical activities. The aim of this study was to detect underlying mechanical thresholds in an experimental model of DOMS. Methods Randomised study to detect mechanical pain thresholds in a randomised order following experimentally induced DOMS of the non-dominant arm in healthy participants. Main outcome was the detection of the pressure pain threshold (PPT), secondary thresholds included mechanical detection (MDT) and pain thresholds (MPT), pain intensity, pain perceptions and the maximum isometric voluntary force (MIVF). Results Twenty volun…

Hypokalemic rhabdomyolysis associated with Bartter's syndrome.

1983

Severe potassium deficiency is an uncommon cause of rhabdomyolysis. We recently treated a 45-year-old patient with myalgia, serious generalized weakness, increased serum creatine kinase and myoglobin level as well as excessive hypokalemia. Histological examination of deltoid muscle biopsy showed rhabdomyolysis. After complete recovery of muscle damage by potassium substitution Bartter's syndrome proved to be the cause of initial and persistent hypokalemia.

Myoadenylate deaminase deficiency

1987

Myoadenylate deaminase (MAD) is the rate-limiting enzyme in the purine nucleotide cycle which is biochemically linked to glycolysis and the citric cycle and thereby providing energy during intense muscular activity. In muscle fibers, myoadenylate deaminase operates at considerably higher activity levels than in other organs. First detected using enzyme-histochemical methods, it now appears that deficiency of myoadenylate deaminase is one of the most frequent enzyme defects in muscle. The primary defect may occur as an isolated nosological entity or not infrequently it is also associated with a large spectrum of different neuromuscular conditions. It seems to be the primary unassociated MAD …

Inhibition of xanthine oxidase to prevent statin-induced myalgia and rhabdomiolysis

2015

Although statins remain the cornerstone of lipid-lowering therapy for reducing the burden of atherosclerotic vascular disease, their administration has been associated with muscle-related adverse effects, including myalgia and rhabdomyolysis. Such adverse events are probably due to reduced antioxidant defenses associated with fewer intermediate metabolites in the cholesterol synthesis pathway. We hypothesize that the concomitant inhibition of xanthine oxidase via coadministration of allopurinol with statins could diminish reactive oxygen species (ROS)-related muscle damage, which would have in turn have positive effects on both the incidence of muscle-related adverse events and cardiovascul…

Plasma markers of platelet and polymorphonuclear leukocyte activation in young adults with acute myocardial infarction

2005

Our goal was to evaluate some plasma markers of platelet and polymorphonuclear leukocyte (PMN) activation in a group of young adults with acute myocardial infarction (AMI) at the initial stage and after three months. We enrolled 49 AMI subjects aged<45 years and examined plasmatic levels of platelet factor 4 (PF4), β-thromboglobulin (β-TG), elastase and myeloperoxidase (MPO) using ELISA methods. PF4 and β-TG were increased, compared to control subjects, both at the initial stage and after 3 months. In control subjects and in AMI patients, at both times of observation, there was a significant and positive correlation between the two platelet parameters, while no correlation was present betwe…

TDI and myocardial blush: good indicators of myocardial reperfusion

2016

The TDI at follow-up confirms the reliability's value of Blush is predicting anatomical and functional recovery of the myocardium and microcirculation.

Hsp60 and heme oxygenase-1 (Hsp32) in acute myocardial infarction (vol 157, pg 285, 2011)

2011

Stymulacja pęczka Hisa u osoby starszej z proksymalnym blokiem przedsionkowo-komorowym po zawale mięśnia sercowego

2018

Stymulacja pęczka Hisa (HBP) umożliwia synchronizację przedsionkowo-komorową i międzykomorową. W opisanym przypadku zwrócono uwagę na związek między poziomem bloku, synchronią komorową oraz funkcją rozkurczową u chorego z umiarkowaną dysfunkcją skurczową lewej komory świeżo po zawale serca. HBP jest korzystna w leczeniu zaburzeń przewodzenia i zapobieganiu dalszym zaburzeniom funkcji skurczowej i rozkurczowej. W artykule przedstawiono przypadek 92-letniego mężczyzny w bardzo dobrym stanie psychofizycznym z napadowym blokiem przedsionkowo-komorowym II stopnia i utrwalonym długim odstępem PR w przebiegu zawału mięśnia sercowego bez uniesienia odcinka ST-T, leczonego angioplastyką gałęzi okala…

The influence of severe mitral regurgitation on major adverse cardiac and cerebrovascular events after myocardial infarction in 1-year follow-up: Dat…

2023

Background: Mitral regurgitation (MR) is frequently observed in patients with myocardial infarction (MI). However, the incidence of severe MR in contemporary population is unknown. Aims: The study evaluates the prevalence and prognostic impact of severe MR in contemporary population of patients with ST-segment elevation myocardial infarction (STEMI) and non-ST-segment elevation myocardial infarction (NSTEMI). Methods: The study group consists of 8062 patients enrolled in the Polish Registry of Acute Coronary Syndromes over the years 2017‒2019. Only the patients with full echocardiography performed during the index hospitalization were eligible. Primary composite outcome was 12-month major a…

Three-year mortality after acute myocardial infarction in patients with different diabetic status

2021

Introduction: The prevalence of diabetes mellitus (DM) in patients with myocardial infarction (MI) is estimated at about 25%. Short and long-term prognoses are worse in DM and hyperglycemia compared with non-diabetics. Objectives: Our aim was to analyze the impact of DM and transient hyperglycemia on in-hospital complications and long-term outcomes in MI patients. Patients and Methods: We evaluated a prospective cohort of 58,394 MI patients in the Polish Registry of Acute Coronary Syndrome in terms of in-hospital complications and 30-day, 12-month, and 36-month outcomes between 2009–2012. Results: Type 1 and 2 DM patients underwent invasive diagnostic and therapeutic procedures less frequen…