0000000000005068
AUTHOR
M. Jovani
Lactoferrin and Its Possible Role in Iron Enrichment of Infant Formulas
Se han descrito las propiedades y funciones de la lactoferrina respecto a su utilizacion en el enriquecimiento de las formulas para lactantes. Se ha prestado especial atencion a las funciones de la lactoferrina directamente relacionadas con su capacidad para fijar hierro: poder bacteriostatico, efecto sobre la absorcion de hierro y poder antioxidante. De los resultados obtenidos por diferentes autores se desprende que la adicion de lactoferrina, generalmente bovina, a las formulas para lactantes no afecta a la absorcion de hierro. No obstante, debido a su capacidad de fijacion de hierro su adicion a las formulas podria ser de utilidad por los siguientes motivos: su efecto protector en el tr…
In vitro interactions between calcium, zinc, copper and iron in milk- and soy-based infant formulas / Interacciones in vitro entre calcio, cinc, cobre e hierro en formulas de base láctea y de soja para lactantes
Interactions among calcium, zinc, copper and iron in milk- and soy-based infant formulas were as sessed in order to evaluate the influence of supplementation with one trace element on the bioavailability of the others. The criterion used to estimate the bioavailability is the percentage of dialysis, estimated by applying an in vitro method. Infant formulas were supplemented with CaCl2, ZnO, CuCO3 Cu(OH) 22H2O and FeSO4 7H2O at two levels (maximum (+) and minimum (-) allowed by the European Union). A factorial design at two levels with three factors (Zn, Cu and Fe addition) was carried out. The main effects and the second-order interactions of the studied factors on the bioavailability of a…
Effect of proteins, phytates, ascorbic acid and citric acid on dialysability of calcium, iron, zinc and copper in soy-based infant formulas.
The possible effect of ascorbic acid, citric acid, proteins and phytate on dialysability of Ca, Fe, Zn and Cu in soy-based infant formulas is studied, taking dialysability as a measure of the amount of element available for absorption. Different dialysis percentages for similar element contents in different formulas are found. A regression analysis was applied between Ca, Zn, Cu and Fe dialysis percentages and soy-based formula components to estimate the possible influence of the latter on the dialysability of the elements. Significant correlations were found between citric acid contents and dialysability of Zn and Fe. No correlations were found between protein, ascorbic acid and phytic aci…
Review: Effect of Some Components of Milk- and Soy-Based Infant Formulas on Mineral Bioavailability
Infants' high nutritional needs are fulfilled by mother's milk or infant formulas to provide all the necessary nutrients, among them minerals. Minerals uptake depends not only on mineral content but also on their bioavailability which, in turn, is affected by the different components of the infant formulas. An understanding of these effects would help to improve mineral bioavailability. This work reviews the influence of endogenous (proteins and phytates) and added (ascorbic and citric acid) components in infant formulas on the bioavailability of nutritionally important mineral elements (calcium, zinc, iron and copper) and their interactions. Special attention is given to the influence of p…
Calcium, Iron, and Zinc Uptake from Digests of Infant Formulas by Caco-2 Cells
Our aim was to estimate the bioavailability of calcium, iron, and zinc from infant formulas using a model that includes in vitro digestion and a Caco-2 cell culture to estimate the uptake. The cell culture conditions were selected, and uptake assays were carried out first with calcium, iron, and zinc standard solutions, and then with the soluble fraction of enzymatic digests of an adapted milk-based and a soy-based infant formula. It was not possible to measure the uptake of calcium, iron, and zinc from standard solutions added to the cell cultures in amounts similar to those present in infant formula digests with our method. The fact that it was, however, possible in the case of enzymatic …