0000000000011662
AUTHOR
S. Perrin
A New Prognosis Score to Predict Mortality After Acute Pneumonia in Very Elderly Patients
International audience; Objectives: Acute pneumonia (AP) induces an excess of mortality among the elderly. We evaluated the value of a new predictive biomarker index compared to usual prognosis scores for predicting in-hospital and 1-year mortalities in elderly inpatients with AP.Design: Retrospective study in 6 clinical departments of a university hospital.Setting: Burgundy university hospital (France).Participants: All patients aged 75 and over with AP and hospitalized between January 1 and June 30, 2013, in the departments of medicine (5) and intensive care (1) of our university hospital.Measurements: A new index, which we named UBMo, was created by multiplying the uremia (U in the formu…
First measurement of the |t|-dependence of coherent J/ψ photonuclear production
The first measurement of the dependence on $|t|$, the square of the momentum transferred between the incoming and outgoing target nucleus, of coherent J/ψ photoproduction is presented. The data were measured with the ALICE detector in ultra-peripheral Pb-Pb collisions at a centre-of-mass energy per nucleon pair $\sqrt{s_{\rm NN}} = 5.02$ TeV with the J/$\psi$ produced in the central rapidity region $|y| < 0.8$, which corresponds to the small Bjorken-$x$ range $(0.3 − 1.4) \times 10 ^{−3}$. The measured $|t|$-dependence is not described by computations based only on the Pb nuclear form factor, while the photonuclear cross section is better reproduced by models including shadowing according t…
Successful management of heparin-induced thrombocytopenia using argatroban in a very old woman: a case report.
Thrombosis due to heparin-induced thrombocytopenia (HIT) is rare but has a severe prognosis. Its management is not always easy, particularly in old patients with renal insufficiency. A 95-year-old woman was hospitalized for dyspnea. Curative treatment with unfractionated heparin was started because pulmonary embolism was suspected. Disseminated intravascular coagulation was then suspected because of thrombocytopenia, hypoprothrombinemia, hypofibrinogenemia, and a positive ethanol gelation test. The first immunoassay for HIT was negative. On the 12th day of hospitalization, bilateral cyanosis of the toes occurred associated with recent deep bilateral venous and arterial thrombosis at duplex …
Blood Transfusion in Elderly Patients with Acute Myocardial Infarction: Data from the RICO Survey.
Red blood cell transfusion benefit during acute myocardial infarction remains unclear in the elderly. We aimed to assess the transfusion impact on 1-year mortality in acute myocardial infarction patients aged ≥65 years, according to their age and hemoglobin nadir.We included 3316 consecutive patients with acute myocardial infarction aged ≥65 years from the "obseRvatoire des Infarctus de Côte d'Or" (RICO) survey. They were categorized according to their hemoglobin nadir (≤8,8 to ≤10, and10 g/dL) and age (80 or ≥80 years).A total of 1906 patients (57%) were 65-79 years old, and 1410 (43%) were aged ≥80 years, of whom 103 (5%) and 145 (10%) patients received red blood cell transfusion, respect…
Dielectron production in proton-proton and proton-lead collisions at √sNN=5.02TeV
The first measurements of dielectron production at midrapidity (|ηe| < 0.8) in proton–proton and proton–lead collisions at √sNN = 5.02 TeV at the LHC are presented. The dielectron cross section is measured with the ALICE detector as a function of the invariant mass mee and the pair transverse momentum pT, ee in the ranges mee < 3.5 GeV/c2 and pT, ee < 8 GeV/c, in both collision systems. In proton–proton collisions, the charm and beauty cross sections are determined at midrapidity from a fit to the data with two different event generators. This complements the existing dielectron measurements performed at √s = 7 and 13 TeV. The slope of the √s dependence of the three measurements is…
Potentially inappropriate use of furosemide in a very elderly population: An observational study
International audience; ObjectiveLittle is known about furosemide prescription modalities in elderly people. We describe furosemide prescription in ambulatory elderly patients.MethodsAll patients aged over 80 years, affiliated to Mutualité Sociale Agricole de Bourgogne, a French regional health insurance plan, with a medical prescription delivered in March 2015, were retrospectively included.ResultsAmong 15 141 patients with a median age of 86 years, comprising 61.3% of women, 3937 patients (26%) had a prescription for furosemide. Severe heart failure was the most common chronic comorbidity (27.7%). Furosemide was considered a long-term therapy for almost all patients (98.7% with prescripti…
Measurements of mixed harmonic cumulants in Pb–Pb collisions at sNN=5.02 TeV
Correlations between moments of different flow coefficients are measured in Pb–Pb collisions at sNN=5.02 TeV recorded with the ALICE detector. These new measurements are based on multiparticle mixed harmonic cumulants calculated using charged particles in the pseudorapidity region |η|<0.8 with the transverse momentum range 0.2<pT<5.0 GeV/c. The centrality dependence of correlations between two flow coefficients as well as the correlations between three flow coefficients, both in terms of their second moments, are shown. In addition, a collection of mixed harmonic cumulants involving higher moments of v2 and v3 is measured for the first time, where the characteristic signature of ne…
La couverture vaccinale contre la grippe saisonnière du personnel soignant en gériatrie : mise au point
Resume Position du probleme La vaccination antigrippale des professionnels de sante semble representer l’une des actions preventives des plus efficaces face a une pathologie a haut risque d’epidemie nosocomiale et potentiellement grave en milieu geriatrique. Ce travail avait pour objectif de faire une mise au point sur le statut vaccinal antigrippal chez le personnel soignant en geriatrie et les raisons expliquant leur reticence vis-a-vis de cette vaccination, afin d’emettre des propositions d’amelioration de la couverture vaccinale. Methode Une recherche bibliographique des articles publies depuis 2000 dans le domaine de la geriatrie, des maladies infectieuses ou de la pneumologie a ete re…
Iléite à cytomégalovirus chez une personne âgée non immunodéprimée : à propos d’une observation
Resume Introduction Les ileites a cytomegalovirus surviennent rarement chez l’immunocompetent. Observation Une femme, âge de 88 ans, presentait une douleur intense de la fosse iliaque droite. La C-reactive proteine etait elevee et associee a une hyperleucocytose a polynucleaires neutrophiles. La coloscopie revelait un aspect tres ulcere et inflammatoire de la muqueuse ileale terminale. L’analyse anatomopathologique des biopsies retrouvait un effet cytopathogene typique avec cellules ballonisees et inclusions intranucleaires, confirme par un immunomarquage positif a l’anticorps anti-cytomegalovirus. La recherche de cytomegalovirus par PCR dans le plasma etait positive. L’evolution clinico-bi…
CCDC 117866: Experimental Crystal Structure Determination
Related Article: S.Perrin, K.Monnier, B.Laude, M.Kubicki, O.Blacque|1999|Eur.J.Org.Chem.|1999|297|doi:10.1002/(SICI)1099-0690(199901)1999:13.0.CO;2-J
CCDC 101489: Experimental Crystal Structure Determination
Related Article: S.Perrin, K.Monnier, B.Laude, M.Kubicki, O.Blacque|1999|Eur.J.Org.Chem.|1999|297|doi:10.1002/(SICI)1099-0690(199901)1999:13.0.CO;2-J