Search for the Higgs Boson in theH→WW(*)→l+νl−ν¯Decay Channel inppCollisions ats=7  TeVwith the ATLAS Detector

A search for the Higgs boson has been performed in the H -> WW(*()) -> l+vl-(v) over bar channel (l = e/mu) with an integrated luminosity of 2.05 fb(-1) of pp collisions at root s = 7 TeV collected with the ATLAS detector at the Large Hadron Collider. No significant excess of events over the expected background is observed and limits on the Higgs boson production cross section are derived for a Higgs boson mass in the range 110 GeV< m(H) < 300 GeV. The observations exclude the presence of a standard model Higgs boson with a mass 145 < m(H) < 206 GeV at 95% confidence level.

Search for new phenomena in the WW→lνl′ν′ final state in pp collisions at s=7TeV with the ATLAS detector

This Letter reports a search for a heavy particle that decays to WW using events produced in pp collisions at root s = 7 TeV. The data were recorded in 2011 by the ATLAS detector and correspond to an integrated luminosity of 4.7 fb(-1). WW -> lvl'v' (l,l' = e or mu) final states are considered and the distribution of the transverse mass of the W W candidates is found to be consistent with Standard Model expectations. Upper limits on the production cross section times branching ratio into W boson pairs are set for Randall-Sundrum and bulk Randall-Sundrum gravitons, which result in observed 95% CL lower limits on the masses of the two particles of 1.23 TeV and 0.84 TeV, respectively.

Search for contact interactions and large extra dimensions in dilepton events fromppcollisions ats=7  TeVwith the ATLAS detector

A search for nonresonant new phenomena, originating from either contact interactions or large extra spatial dimensions, has been carried out using events with two isolated electrons or muons. These events, produced at the LHC in proton-proton collisions at root s = 7 TeV, were recorded by the ATLAS detector. The data sample, collected throughout 2011, corresponds to an integrated luminosity of 4.9 and 5.0 fb(-1) in the e(+)e(-) and mu(+)mu(-) channels, respectively. No significant deviations from the Standard Model expectation are observed. Using a Bayesian approach, 95% confidence level lower limits ranging from 9.0 to 13.9 TeV are placed on the energy scale of llqq contact interactions in…

Measurement of the Higgs boson mass from theH→γγandH→ZZ*→4ℓchannels inppcollisions at center-of-mass energies of 7 and 8 TeV with the ATLAS detector

An improved measurement of the mass of the Higgs boson is derived from a combined fit to the reconstructed invariant mass spectra of the decay channels H -> gamma gamma and H -> ZZ* -> 4l. The analysis uses the pp collision data sample recorded by the ATLAS experiment at the CERN Large Hadron Collider at center-of-mass energies of 7 TeV and 8 TeV, corresponding to an integrated luminosity of 25 fb(-1). The measured value of the Higgs boson mass is m(H) = 125.36 +/- 0.37(stat) +/- 0.18 (syst) GeV. This result is based on improved energy-scale calibrations for photons, electrons, and muons as well as other analysis improvements, and supersedes the previous result from ATLAS. Upper limits on t…

Measurement of the top pair production cross section in 8 TeV proton-proton collisions using kinematic information in thelepton+jetsfinal state with ATLAS

A measurement is presented of the (tt) over bar inclusive production cross section in pp collisions at a center-ofmass energy of pffisffiffi root s = 8 TeV using data collected by the ATLAS detector at the CERN Large Hadron Collider. The measurement was performed in the lepton + jets final state using a data set corresponding to an integrated luminosity of 20.3 fb(-1). The cross section was obtained using a likelihood discriminant fit and b-jet identification was used to improve the signal-to-background ratio. The inclusive (tt) over bar production cross section was measured to be 260 +/- 1(stat)(-23)(+22)(stat) +/- 8(lumi) +/- 4(beam) pb assuming a top-quark mass of 172.5 GeV, in good agre…

Measurement of the azimuthal anisotropy for charged particle production insNN=2.76TeV lead-lead collisions with the ATLAS detector

Differential measurements of charged particle azimuthal anisotropy are presented for lead-lead collisions at root sNN = 2.76 TeV with the ATLAS detector at the LHC, based on an integrated luminosity of approximately 8 mu b(-1). This anisotropy is characterized via a Fourier expansion of the distribution of charged particles in azimuthal angle relative to the reaction plane, with the coefficients v(n) denoting the magnitude of the anisotropy. Significant v(2)-v(6) values are obtained as a function of transverse momentum (0.5 = 3 are found to vary weakly with both eta and centrality, and their p(T) dependencies are found to follow an approximate scaling relation, v(n)(1/n)(p(T)) proportional …

Evidence ofWγγProduction inppCollisions ats=8  TeVand Limits on Anomalous Quartic Gauge Couplings with the ATLAS Detector

This Letter reports evidence of triple gauge boson production pp -> W(l nu)gamma gamma + X, which is accessible for the first time with the 8 TeV LHC data set. The fiducial cross section for this process is measured in a data sample corresponding to an integrated luminosity of 20.3 fb(-1), collected by the ATLAS detector in 2012. Events are selected using the W boson decay to e nu or mu nu as well as requiring two isolated photons. The measured cross section is used to set limits on anomalous quartic gauge couplings in the high diphoton mass region.

Measurement of charged-particle event shape variables in inclusive(s)=7  TeVproton-proton interactions with the ATLAS detector

The measurement of charged-particle event shape variables is presented in inclusive inelastic pp collisions at a center-of-mass energy of 7 TeV using the ATLAS detector at the LHC. The observables studied are the transverse thrust, thrust minor, and transverse sphericity, each defined using the final-state charged particles' momentum components perpendicular to the beam direction. Events with at least six charged particles are selected by a minimum-bias trigger. In addition to the differential distributions, the evolution of each event shape variable as a function of the leading charged-particle transverse momentum, charged-particle multiplicity, and summed transverse momentum is presented.…

Measurement of the cross section of high transverse momentumZ→bb¯production in proton–proton collisions ats=8 TeVwith the ATLAS detector

This Letter reports the observation of a high transverse momentum Z -> b (b) over bar signal in proton-proton collisions at root s = 8TeVand the measurement of its production cross section. The data analysed were collected in 2012 with the ATLAS detector at the LHC and correspond to an integrated luminosity of 19.5 fb(-1). The Z -> b (b) over bar decay is reconstructed from a pair of b-tagged jets, clustered with the anti- k(t) jet algorithm with R = 0.4, that have low angular separation and form a dijet with p(T) > 200 GeV. The signal yield is extracted from a fit to the dijet invariant mass distribution, with the dominant, multi-jet background mass shape estimated by employing a fully dat…

Study of jets produced in association with aWboson inppcollisions ats=7  TeVwith the ATLAS detector

We report a study of final states containing a W boson and hadronic jets, produced in proton-proton collisions at a center-of-mass energy of 7 TeV. The data were collected with the ATLAS detector at the CERN LHC and comprise the full 2010 data sample of 36 pb^-1. Cross sections are determined using both the electron and muon decay modes of the W boson and are presented as a function of inclusive jet multiplicity, N_jet, for up to five jets. At each multiplicity, cross sections are presented as a function of jet transverse momentum, the scalar sum of the transverse momenta of the charged lepton, missing transverse momentum, and all jets, the invariant mass spectra of jets, and the rapidity d…

Interfacial Dzyaloshinskii-Moriya interaction and chiral magnetic textures in a ferrimagnetic insulator

The interfacial Dzyaloshinskii-Moriya interaction (DMI) in multilayers of heavy metal and ferromagnetic metals enables the stabilization of novel chiral spin structures such as skyrmions. Magnetic insulators, on the other hand can exhibit enhanced dynamics and properties such as lower magnetic damping and therefore it is of interest to combine the properties enabled by interfacial DMI with insulating systems. Here, we demonstrate the presence of interfacial DMI in heterostructures that include insulating magnetic layers. We use a bilayer of perpendicularly magnetized insulating thulium iron garnet (TmIG) and the heavy metal platinum, and find a surprisingly strong interfacial DMI that, comb…

Real-Life Study for the Diagnosis of House Dust Mite Allergy - The Value of Recombinant Allergen-Based IgE Serology.

&lt;b&gt;&lt;i&gt;Background:&lt;/i&gt;&lt;/b&gt;&lt;i&gt;Dermatophagoides pteronyssinus&lt;/i&gt; is one of the most important perennial allergen sources worldwide. Molecular diagnostics using the commercially available major allergens (Der p 1 and Der p 2) in combination with Der p 10 do not detect house dust mite (HDM) sensitization in a number of cases when used alone. The objective was to evaluate the IgE reactivity profiles of these patients using an experimental immunoassay biochip. &lt;b&gt;&lt;i&gt;Methods: &lt;/i&gt;&lt;/b&gt;Sera of HDM-allergic patients (positive skin prick test, CAP class ≥1 for allergen extract, and positive intranasal provocation) were tested for IgE antibodi…

Search for Dark Matter in Events with a Hadronically DecayingWorZBoson and Missing Transverse Momentum inppCollisions ats=8  TeVwith the ATLAS Detector

A search is presented for dark matter pair production in association with a W or Z boson in pp collisions representing 20.3 fb(-1) of integrated luminosity at root s = 8 TeV using data recorded with the ATLAS detector at the Large Hadron Collider. Events with a hadronic jet with the jet mass consistent with a W or Z boson, and with large missing transverse momentum are analyzed. The data are consistent with the standard model expectations. Limits are set on the mass scale in effective field theories that describe the interaction of dark matter and standard model particles, and on the cross section of Higgs production and decay to invisible particles. In addition, cross section limits on the…

Search for new phenomena in events with a photon and missing transverse momentum inppcollisions ats=8  TeVwith the ATLAS detector

© 2015 CERN. © 2015 CERN, for the ATLAS Collaboration. Published by the American Physical Society under the terms of the »http://creativecommons.org/licenses/by/3.0/» Creative Commons Attribution 3.0 License. Further distribution of this work must maintain attribution to the author(s) and the published article's title, journal citation, and DOI. Results of a search for new phenomena in events with an energetic photon and large missing transverse momentum with the ATLAS experiment at the LHC are reported. Data were collected in proton-proton collisions at a center-of-mass energy of 8 TeV and correspond to an integrated luminosity of 20.3 fb-1. The observed data are well described by the expe…

Current therapeutical strategies for allergic rhinitis

Allergic rhinitis is a common condition with increasing prevalence and is associated with several comorbid disorders such as bronchial asthma and atopic dermatitis. If allergen avoidance is not possible, allergen-specific immunotherapy is the only causal treatment option.This review focuses on current treatments and the future outlook for allergic rhinitis. Pharmacotherapy includes mast cell stabilizers, antihistamines, glucocorticosteroids (GCSs), leukotriene receptor antagonists, and nasal decongestants. Nasal GCSs are currently regarded as the most effective treatment and are considered first-line therapy together with non-sedating antihistamines. The new formulation MP29-02 combines the…

Search for supersymmetry in final states with jets, missing transverse momentum and one isolated lepton ins=7  TeVpp collisions using1  fb−1of ATLAS data

We present an update of a search for supersymmetry in final states containing jets, missing transverse momentum, and one isolated electron or muon, using 1.04 fb(-1) of proton-proton collision data at root s =7 TeV recorded by the ATLAS experiment at the LHC in the first half of 2011. The analysis is carried out in four distinct signal regions with either three or four jets and variations on the (missing) transverse momentum cuts, resulting in optimized limits for various supersymmetry models. No excess above the standard model background expectation is observed. Limits are set on the visible cross section of new physics within the kinematic requirements of the search. The results are inter…

The role of structured surgical planning in the learning process of functional endoscopic sinus surgery

Search fortbResonances in Proton-Proton Collisions ats=7  TeVwith the ATLAS Detector

This Letter presents a search for tb resonances in 1.04 fb(-1) of LHC proton-proton collision data collected by the ATLAS detector at a center-of-mass energy of 7 TeV. Events with a lepton, missing transverse momentum, and two jets are selected and the invariant mass of the corresponding final state is reconstructed. The search exploits the shape of the tb invariant mass distribution compared to the expected standard model backgrounds. The model of a right-handed W(R)' with standard model-like couplings is chosen as the benchmark model for this search. No statistically significant excess of events is observed in the data, and upper limits on the cross section times the branching ratio of W(…

Search for a multi-Higgs-boson cascade inW+W−bb¯events with the ATLAS detector inppcollisions ats=8  TeV

A search is presented for new particles in an extension to the Standard Model that includes a heavy Higgs boson (H-0), an intermediate charged Higgs-boson pair (H-+/-), and a light Higgs boson (h(0)). The analysis searches for events involving the production of a single heavy neutral Higgs boson which decays to the charged Higgs boson and a W boson, where the charged Higgs boson subsequently decays into a W boson and the lightest neutral Higgs boson decaying to a bottom-antibottom-quark pair. Such a cascade results in a W-boson pair and a bottom-antibottom-quark pair in the final state. Events with exactly one lepton, missing transverse momentum, and at least four jets are selected from a d…

Identifying the origin of the nonmonotonic thickness dependence of spin-orbit torque and interfacial Dzyaloshinskii-Moriya interaction in a ferrimagnetic insulator heterostructure

Electrical manipulation of magnetism via spin-orbit torques (SOTs) promises efficient spintronic devices. In systems comprising magnetic insulators and heavy metals, SOTs have started to be investigated only recently, especially in systems with interfacial Dzyaloshinskii-Moriya interaction (iDMI). Here, we quantitatively study the SOT efficiency and iDMI in a series of gadolinium gallium garnet (GGG) / thulium iron garnet (TmIG) / platinum (Pt) heterostructures with varying TmIG and Pt thicknesses. We find that the non-monotonic SOT efficiency as a function of the magnetic layer thickness is not consistent with the 1/thickness dependence expected from a simple interfacial SOT mechanism. Mor…

Measurement of the transverse polarization ofΛandΛ¯hyperons produced in proton-proton collisions ats=7  TeVusing the ATLAS detector

The transverse polarization of Λ and Λ¯ hyperons produced in proton-proton collisions at a center-of-mass energy of 7 TeV is measured. The analysis uses 760  μb−1 of minimum bias data collected by the ATLAS detector at the LHC in the year 2010. The measured transverse polarization averaged over Feynman xF from 5×10−5 to 0.01 and transverse momentum pT from 0.8 to 15 GeV is −0.010±0.005(stat)±0.004(syst) for Λ and 0.002±0.006(stat)±0.004(syst) for Λ¯. It is also measured as a function of xF and pT, but no significant dependence on these variables is observed. Prior to this measurement, the polarization was measured at fixed-target experiments with center-of-mass energies up to about 40 GeV. …

Search for the decay Bs0→μ+μ− with the ATLAS detector

A blind analysis searching for the decay B-s(0) -> mu(+)mu(-) has been performed using proton-proton collisions at a centre-of-mass energy of 7 TeV recorded with the ATLAS detector at the LHC. W ...

Surface Modification of Porous Polyethylene Implants with an Albumin-Based Nanocarrier-Release System

Background: Porous polyethylene (PPE) implants are used for the reconstruction of tissue defects but have a risk of rejection in case of insufficient ingrowth into the host tissue. Various growth factors can promote implant ingrowth, yet a long-term gradient is a prerequisite for the mediation of these effects. As modification of the implant surface with nanocarriers may facilitate a long-term gradient by sustained factor release, implants modified with crosslinked albumin nanocarriers were evaluated in vivo. Methods: Nanocarriers from murine serum albumin (MSA) were prepared by an inverse miniemulsion technique encapsulating either a low- or high-molar mass fluorescent cargo. PPE implants …

Search for resonant top quark plus jet production intt¯+jetsevents with the ATLAS detector inppcollisions ats=7  TeV

This paper presents a search for a new heavy particle produced in association with a top or antitop quark. Two models in which the new heavy particle is a color singlet or a color triplet are considered, decaying, respectively, to (t)over-barq or tq, leading to a resonance within the t(t)over-bar + jets signature. The full 2011 ATLAS pp collision data set from the LHC (4.7 fb(-1)) is used to search for t(t)over-bar events produced in association with jets, in which one of the W bosons from the top quarks decays leptonically and the other decays hadronically. The data are consistent with the Standard Model expectation, and a new particle with mass below 430 Gev for both W' boson and color tr…

Search for Scalar Charm Quark Pair Production inppCollisions ats=8  TeVwith the ATLAS Detector

The results of a dedicated search for pair production of scalar partners of charm quarks are reported. The search is based on an integrated luminosity of 20.3 fb(-1) of pp collisions at root s = 8 TeV recorded with the ATLAS detector at the LHC. The search is performed using events with large missing transverse momentum and at least two jets, where the two leading jets are each tagged as originating from c quarks. Events containing isolated electrons or muons are vetoed. In an R-parity-conserving minimal super-symmetric scenario in which a single scalar-charm state is kinematically accessible, and where it decays exclusively into a charm quark and a neutralino, 95% confidence-level upper li…

Search for dark matter candidates and large extra dimensions in events with a jet and missing transverse momentum with the ATLAS detector

A search for new phenomena in events with a high-energy jet and large missing transverse momentum is performed using data from proton-proton collisions at √s = 7 TeV with the ATLAS experiment at the Large Hadron Collider. Four kinematic regions are explored using a dataset corresponding to an integrated luminosity of 4.7 fb[superscript −1]. No excess of events beyond expectations from Standard Model processes is observed, and limits are set on large extra dimensions and the pair production of dark matter particles.

Is Quantitative sIgE Serology Suitable for Distinguishing Between Silent Sensitization and Allergic Rhinitis to Dermatophagoides pteronyssinus?

BACKGROUND AND OBJECTIVE An increasing number of studies have recently discussed whether provocation tests might be replaced by specific IgE serology in patients sensitized to airborne allergens. Objective: Our study aimed to analyze the concordance between a nasal provocation test with Dermatophagoides pteronyssinus and specific IgE measurements based on real-life data. METHODS We retrospectively analyzed concordance between the result of the provocation test and the IgE titer for house dust mite components and extracts in 223 patients with proven sensitization to D pteronyssinus. RESULTS In contrast to findings from other studies, the anti-Der p 1 level alone was not sufficient to disting…

The challenge in realizing an exchange coupled BiFeO3-double perovskite bilayer

Abstract In this work we propose a device design for efficient voltage control of magnetism. The magnetization of a ferrimagnetic double perovskite may be manipulated by an exchange coupled layer of multiferroic BiFeO3. Bilayers of Barium doped BiFeO3 and ferrimagnetic double perovskite Sr2FeMoO6 have been prepared by pulsed laser deposition motivated by the possibility of strong interlayer exchange coupling. While single layers of each material show high quality we observe that in both stacking orders the first layer decomposes during the deposition of the second layer. The reason for the decomposition are strongly differing growth conditions for BiFeO3 and Sr2FeMoO6. This means that the g…

A neural network clustering algorithm for the ATLAS silicon pixel detector

A novel technique to identify and split clusters created by multiple charged particles in the ATLAS pixel detector using a set of artificial neural networks is presented. Such merged clusters are a common feature of tracks originating from highly energetic objects, such as jets. Neural networks are trained using Monte Carlo samples produced with a detailed detector simulation. This technique replaces the former clustering approach based on a connected component analysis and charge interpolation. The performance of the neural network splitting technique is quantified using data from proton-proton collisions at the LHC collected by the ATLAS detector in 2011 and from Monte Carlo simulations. …

Search for Dark Matter Candidates and Large Extra Dimensions in Events with a Photon and Missing Transverse Momentum inppCollision Data ats=7  TeVwith the ATLAS Detector

Search for Pair Production of a Newb′Quark that Decays into aZBoson and a Bottom Quark with the ATLAS Detector

A search is reported for the pair production of a new quark b' with at least one b' decaying to a Z boson and a bottom quark. The data, corresponding to 2.0 fb(-1) of integrated luminosity, were co ...

Determination of the Ratio ofb-Quark Fragmentation Fractionsfs/fdinppCollisions ats=7  TeVwith the ATLAS Detector

With an integrated luminosity of 2.47 fb^{-1} recorded by the ATLAS experiment at the LHC, the exclusive decays B_{s}^{0}→J/ψϕ and B_{d}^{0}→J/ψK^{*0} of B mesons produced in pp collisions at sqrt[s]=7 TeV are used to determine the ratio of fragmentation fractions f_{s}/f_{d}. From the observed B_{s}^{0}→J/ψϕ and B_{d}^{0}→J/ψK^{*0} yields, the quantity (f_{s}/f_{d})[B(B_{s}^{0}→J/ψϕ)/B(B_{d}^{0}→J/ψK^{*0})] is measured to be 0.199±0.004(stat)±0.008(syst). Using a recent theory prediction for [B(B_{s}^{0}→J/ψϕ)/B(B_{d}^{0}→J/ψK^{*0})] yields (f_{s}/f_{d})=0.240±0.004(stat)±0.010(syst)±0.017(th). This result is based on a new approach that provides a significant improvement of the world aver…

Measurement of the production cross section of an isolated photon associated with jets in proton-proton collisions ats=7  TeVwith the ATLAS detector

A measurement of the cross section for the production of an isolated photon in association with jets in proton-proton collisions at a center-of-mass energy root s = 7 TeV is presented. Photons are ...

Measurement of theZZProduction Cross Section and Limits on Anomalous Neutral Triple Gauge Couplings in Proton-Proton Collisions ats=7  TeVwith the ATLAS Detector

A measurement of the ZZ production cross section in proton-proton collisions at root s = 7 TeV using data corresponding to an integrated luminosity of 1.02 fb(-1) recorded by the ATLAS experiment a ...

Modulation of Exposure to Static Magnetic Field Affects Targeted Therapy of Solid Tumors In Vivo

Background Static magnetic fields (SMF) exhibit antitumoral activity and enhance the efficacy of chemotherapy by opening the tumor-blood barrier. This study aimed to analyze different SMF-exposure protocols on epidermal growth factor receptor (EGFR)-overexpressing tumors, as well as their combination with cetuximab. Materials and methods Experiments were performed in skinfold chamber preparations of C57Bl/6-and CD-1nu/nu mice bearing LLC-1 tumors. Animals were exposed to 587 mT magnetic field following different exposure protocols. A subgroup received additional cetuximab injections. Using in vivo-fluorescence microscopy and planimetry, tumor angiogenesis, growth and microcirculation were r…

Further search for supersymmetry ats=7  TeVin final states with jets, missing transverse momentum, and isolated leptons with the ATLAS detector

This work presents a new inclusive search for supersymmetry (SUSY) by the ATLAS experiment at the LHC in proton-proton collisions at a center-of-mass energy root s = 7 TeV in final states with jets, missing transverse momentum and one or more isolated electrons and/or muons. The search is based on data from the full 2011 data-taking period, corresponding to an integrated luminosity of 4.7 fb(-1). Single-lepton and multilepton channels are treated together in one analysis. An increase in sensitivity is obtained by simultaneously fitting the number of events in statistically independent signal regions, and the shapes of distributions within those regions. A dedicated signal region is introduc…

Measurement of the correlation between flow harmonics of different order in lead-lead collisions at sNN=2.76 TeV with the ATLAS detector

Correlations between the elliptic or triangular flow coefficients v(m) (m = 2 or 3) and other flow harmonics v(n) (n = 2 to 5) are measured using root S-NN = 2.76 TeV Pb + Pb collision data collected in 2010 by the ATLAS experiment at the LHC, corresponding to an integrated luminosity of 7 mu b(-1). The v(m)-v(n) correlations aremeasured in midrapidity as a function of centrality, and, for events within the same centrality interval, as a function of event ellipticity or triangularity defined in a forward rapidity region. For events within the same centrality interval, v(3) is found to be anticorrelated with v(2) and this anticorrelation is consistent with similar anticorrelations between th…

Search for a Light Higgs Boson Decaying to Long-Lived Weakly Interacting Particles in Proton-Proton Collisions ats=7  TeVwith the ATLAS Detector

A search for the decay of a light Higgs boson (120-140 GeV) to a pair of weakly interacting, long-lived particles in 1.94 fb(-1) of proton-proton collisions at root s = 7 TeV recorded in 2011 by the ATLAS detector is presented. The search strategy requires that both long-lived particles decay inside the muon spectrometer. No excess of events is observed above the expected background and limits on the Higgs boson production times branching ratio to weakly interacting, long-lived particles are derived as a function of the particle proper decay length.

Search for extra dimensions in diphoton events from proton-proton collisions at root s=7 TeV in the ATLAS detector at the LHC

The large difference between the Planck scale and the electroweak scale, known as the hierarchy problem, is addressed in certain models through the postulate of extra spatial dimensions. A search for evidence of extra spatial dimensions in the diphoton channel has been performed using the full set of proton–proton collisions at √s = 7 TeV recorded in 2011 with the ATLAS detector at the CERN Large Hadron Collider. This dataset corresponds to an integrated luminosity of 4.9fb[superscript −1]. The diphoton invariant mass spectrum is observed to be in good agreement with the Standard Model expectation. In the context of the model proposed by Arkani–Hamed, Dimopoulos and Dvali, 95% confidence le…

Mechanisms of nanotoxicity – biomolecule coronas protect pathological fungi against nanoparticle-based eradication

Whereas nanotoxicity is intensely studied in mammalian systems, our knowledge of desired or unwanted nano-based effects for microbes is still limited. Fungal infections are global socio-economic health and agricultural problems, and current chemical antifungals may induce adverse side-effects in humans and ecosystems. Thus, nanoparticles are discussed as potential novel and sustainable antifungals via the desired nanotoxicity but often fail in practical applications. In our study, we found that nanoparticles' toxicity strongly depends on their binding to fungal spores, including the clinically relevant pathogen

Search for vectorlikeBquarks in events with one isolated lepton, missing transverse momentum, and jets ats=8  TeVwith the ATLAS detector

A search has been performed for pair production of heavy vectorlike down-type (B) quarks. The analysis explores the lepton-plus-jets final state, characterized by events with one isolated charged lepton (electron or muon), significant missing transverse momentum, and multiple jets. One or more jets are required to be tagged as arising from b quarks, and at least one pair of jets must be tagged as arising from the hadronic decay of an electroweak boson. The analysis uses the full data sample of pp collisions recorded in 2012 by the ATLAS detector at the LHC, operating at a center-of-mass energy of 8 TeV, corresponding to an integrated luminosity of 20.3 fb(-1). No significant excess of event…

Search for Dark Matter in Events with Missing Transverse Momentum and a Higgs Boson Decaying to Two Photons inppCollisions ats=8  TeVwith the ATLAS Detector

Results of a search for new phenomena in events with large missing transverse momentum and a Higgs boson decaying to two photons are reported. Data from proton-proton collisions at a center-of-mass energy of 8 TeV and corresponding to an integrated luminosity of 20.3  fb−1 have been collected with the ATLAS detector at the LHC. The observed data are well described by the expected standard model backgrounds. Upper limits on the cross section of events with large missing transverse momentum and a Higgs boson candidate are also placed. Exclusion limits are presented for models of physics beyond the standard model featuring dark-matter candidates.

Propagation Length of Antiferromagnetic Magnons Governed by Domain Configurations.

Spintronics seeks to functionalize antiferromagnetic materials to develop memory and logic devices operating at terahertz speed and robust against external magnetic field perturbations. To be useful, such functionality needs to be developed in thin film devices. The key functionality of long-distance spin-transport has, however, so far only been reported in bulk single crystal antiferromagnets, while in thin films, transport has so far been limited to a few nanometers. In this work, we electrically achieve a long-distance propagation of spin-information in thin films of the insulating antiferromagnet hematite. Through transport and magnetic imaging, we demonstrate a strong correlation betwe…

Allergen-Immuntherapie in der aktuellen COVID-19-Pandemie – ein Positionspapier von ARIA, EAACI, AeDA, GPA und DGAKI (Kurzversion) – Positionspapier der deutschen ARIA-GruppeA in Kooperation mit der österreichischen ARIA-GruppeB, der schweizerischen ARIA-GruppeC, dem Ärzteverband Deutscher Allergologen (AeDA)D, der Deutschen Gesellschaft für Allergologie und Klinische Immunologie (DGAKI)E und der Gesellschaft für Pädiatrische Allergologie (GPA)F in Kooperation mit der AG Klinische Immunologie, Allergologie und Umweltmedizin der DGHNO-KHCG und der Europäischen Akademie für Allergologie und Klinische Immunologie (EAACI)H

Measurement of isolated-photon pair production in pp collisions at root s=7 TeV with the ATLAS detector

The ATLAS experiment at the LHC has measured the production cross section of events with two isolated photons in the final state, in proton-proton collisions at √s = 7 TeV . The full data set collected in 2011, corresponding to an integrated luminosity of 4.9 fb[superscript −1], is used. The amount of background, from hadronic jets and isolated electrons, is estimated with data-driven techniques and subtracted. The total cross section, for two isolated photons with transverse energies above 25 GeV and 22 GeV respectively, in the acceptance of the electromagnetic calorimeter (|η|  0.4, is 44.0[+3.2 over −4.2] pb. The differential cross sections as a function of the di-photon invariant mass, …

Electrical detection of the spin reorientation transition in antiferromagnetic TmFeO3 thin films by spin Hall magnetoresistance

TmFeO$_3$ (TFO) is a canted antiferromagnet that undergoes a spin reorientation transition (SRT) with temperature between 82 K and 94 K in single crystals. In this temperature region, the N\'eel vector continuously rotates from the crystallographic $c$-axis (below 82 K) to the $a$-axis (above 94 K). The SRT allows for a temperature control of distinct antiferromagnetic states without the need for a magnetic field, making it apt for applications working at THz frequencies. For device applications, thin films of TFO are required as well as an electrical technique for reading out the magnetic state. Here we demonstrate that orthorhombic TFO thin films can be grown by pulsed laser deposition an…

Search for Production of Resonant States in the Photon-Jet Mass Distribution UsingppCollisions ats=7  TeVCollected by the ATLAS Detector

This Letter describes a model-independent search for the production of new resonant states in photon + jet events in 2.11 fb(-1) of proton-proton collisions at root s = 7 TeV. We compare the photon ...

Spheroid-based 3D Cell Cultures Enable Personalized Therapy Testing and Drug Discovery in Head and Neck Cancer.

Background/Aim: Chemo-radiation currently serves as first-line therapy of advanced and recurrent head and neck cancer, while new chemotherapy regimens are emerging. However, response rates to any treatment are difficult to predict and underlie broad variation. This study shows the development of a standardized, high-throughput in vitro assay to assess patients' individual response to therapy regimens as a future tool for personalized tumor therapy. Materials and Methods: Viability and proliferation analyses after chemo +/- radiation treatment of single spheroids (low adhesion plates/Hanging Drop (HD)) were generated from head and neck squamous cell carcinoma (HNSCC) cell lines and primary h…

Measurements of Higgs boson production and couplings in the four-lepton channel inppcollisions at center-of-mass energies of 7 and 8 TeV with the ATLAS detector

The final ATLAS Run 1 measurements of Higgs boson production and couplings in the decay channel H -> ZZ* -> l(+)l(-)l(+)l'(-), where l, l' = e or mu, are presented. These measurements were performed using pp collision data corresponding to integrated luminosities of 4.5 and 20.3 fb(-1) at center-of-mass energies of 7 and 8 TeV, respectively, recorded with the ATLAS detector at the LHC. The H -> ZZ* -> 4l signal is observed with a significance of 8.1 standard deviations, with an expectation of 6.2 standard deviations, at m(H) = 125.36 GeV, the combined ATLAS measurement of the Higgs boson mass from the H -> gamma gamma and H -> ZZ* -> 4l channels. The production rate relative to the Standard…

Measurement of the high-mass Drell–Yan differential cross-section in pp collisions at s=7 TeV with the ATLAS detector

This Letter reports a measurement of the high-mass Drell–Yan differential cross-section in proton–proton collisions at a centre-of-mass energy of 7 TeV at the LHC. Based on an integrated luminosity ...

Search for Higgs andZBoson Decays toJ/ψγandϒ(nS)γwith the ATLAS Detector

A search for the decays of the Higgs and Z bosons to J/psi gamma and Upsilon(nS)gamma (n = 1,2,3) is performed with pp collision data samples corresponding to integrated luminosities of up to 20.3 fb(-1) collected at root s = 8 TeV with the ATLAS detector at the CERN Large Hadron Collider. No significant excess of events is observed above expected backgrounds and 95% C.L. upper limits are placed on the branching fractions. In the J/psi gamma final state the limits are 1.5 x 10(-3) and 2.6 x 10(-6) for the Higgs and Z boson decays, respectively, while in the Upsilon(1S, 2S, 3S)gamma. final states the limits are (1.3, 1.9, 1.3) x 10(-3) and (3.4, 6.5, 5.4) x 10(-6), respectively.

Measurement of Top Quark Polarization in Top-Antitop Events from Proton-Proton Collisions ats=7  TeVUsing the ATLAS Detector

This Letter presents measurements of the polarization of the top quark in top-antitop quark pair events, using 4: 7 fb(-1) of proton-proton collision data recorded with the ATLAS detector at the La ...

Observation of Spin Correlation intt¯Events fromppCollisions ats=7  TeVUsing the ATLAS Detector

A measurement of spin correlation in t (t) over bar production is reported using data collected with the ATLAS detector at the LHC, corresponding to an integrated luminosity of 2.1 fb(-1). Candidat ...

Measurements of the top quark branching ratios into channels with leptons and quarks with the ATLAS detector

Measurements of the branching ratios of top quark decays into leptons and jets using events with t[bar over t] (top antitop) pairs are reported. Events were recorded with the ATLAS detector at the LHC in pp collisions at a center-of-mass energy of 7 TeV. The collected data sample corresponds to an integrated luminosity of 4.6  fb[superscript −1]. The measured top quark branching ratios agree with the Standard Model predictions within the measurement uncertainties of a few percent.

Measurement of Spin Correlation in Top-Antitop Quark Events and Search for Top Squark Pair Production inppCollisions ats=8  TeVUsing the ATLAS Detector

A measurement of spin correlation in t (t) over bar production is presented using data collected with the ATLAS detector at the Large Hadron Collider in proton-proton collisions at a center-of-mass ...

Measurement ofW+W−production inppcollisions ats=7  TeVwith the ATLAS detector and limits on anomalousWWZandWWγcouplings

This paper presents a measurement of the W+W- production cross section in pp collisions at root s = 7 TeV. The leptonic decay channels are analyzed using data corresponding to an integrated luminosity of 4: 6 fb(-1) collected with the ATLAS detector at the Large Hadron Collider. The W+W- production cross section sigma(pp -> W+W- + X) is measured to be 51.9 +/- 2.0(stat) +/- 3.9(syst) +/- 2.0(lumi) pb, compatible with the Standard Model prediction of 44.7(-1.9)(+2.1) pb. A measurement of the normalized fiducial cross section as a function of the leading lepton transverse momentum is also presented. The reconstructed transverse momentum distribution of the leading lepton is used to extract li…

Die Rolle der strukturierten Operationsplanung im Lernprozess der funktionell endoskopischen Nasennebenhöhlenchirurgie

Comprehensive measurements oft-channel single top-quark production cross sections ats=7  TeVwith the ATLAS detector

This article presents measurements of the t-channel single top-quark ((t) over bart) and top-antiquark (_ t) total production cross sections sdtq_ and sd _ tq_, their ratio Rt sdtq_= sd _ tq_, and a measurement of the inclusive production cross section sdtq _ _ tq_ in proton-proton collisions at ffiffiffi ps = 7 TeV at the LHC. Differential cross sections for the tq and _ tq processes are measured as a function of the transverse momentum and the absolute value of the rapidity of t and _ t, respectively. The analyzed data set was recorded with the ATLAS detector and corresponds to an integrated luminosity of 4.59 fb-1. Selected events contain one charged lepton, large missing transverse mome…

Search for heavy vector-like quarks coupling to light quarks in proton–proton collisions at s=7 TeV with the ATLAS detector

This letter presents a search for singly produced vector-like quarks, Q, coupling to light quarks, q. The search is sensitive to both charged current (CC) and neutral current (NC) processes, p p --> Q q --> W q q' and p p --> Q q --> Z q q' with a leptonic decay of the vector gauge boson. In 1.04/fb of data taken in 2011 by the ATLAS experiment at a center-of-mass energy sqrt(s) = 7 TeV, no evidence of such heavy vector-like quarks is observed above the expected Standard Model background. Limits on the heavy vector-like quark production cross section times branching ratio as a function of mass m_Q are obtained. For a coupling kappa_(qQ) = v/m_Q, where v is the Higgs vacuum expectation value…

Measurement of the W±Z production cross section and limits on anomalous triple gauge couplings in proton–proton collisions at s=7 TeV with the ATLAS detector

This Letter presents a measurement of W(+/-)Z production in 1.02 fb(-1) of pp collision data at root s = 7 TeV collected by the ATLAS experiment in 2011. Doubly leptonic decay events are selected w ...

Impact of comorbidity and anemia in patients with oropharyngeal cancer primarily treated with surgery in the human papillomavirus era

Background. Comorbidity and anemia strongly influence treatment and outcome of oropharyngeal squamous cell carcinomas (SCCs), but respective data are frequently lacking in clinical studies. We evaluated 149 cases of oropharyngeal SCC primarily treated with surgery regarding the impact of these factors on disease-free survival (DFS) and overall survival (OS). Methods. Data were recorded during treatment and follow-up visits. Human papillomavirus (HPV) association of oropharyngeal SCC was detected by p16 immunohistochemistry. Results. Patients with p16-positive disease were significantly less comorbid and anemic, and treated more aggressively. Comorbidity and anemia, but not p16 status, signi…

Kostenvergleichsanalyse von flexiblen HNO-Endoskopen

Zusammenfassung Hintergrund Die hygienische, richtliniengetreue Wiederaufbereitung von komplexen Instrumenten wie flexiblen HNO-Endoskopen mit und ohne Arbeitskanal stellt Kliniken und Praxen zunehmend vor große Herausforderungen. Ziel der vorliegenden Studie war es daher, die Kosten für ein wiederaufbereitbares Endoskopie-System mit 2 Einweg-Endoskopie-Systemen zu vergleichen und daraus mögliche strategische Überlegungen abzuleiten. Methodik Hierzu wurde eine Kostenvergleichsanalyse bzw. Kostenminimierungsanalyse des an der Hals-, Nasen-, Ohrenklinik und Poliklinik der Universitätsmedizin Mainz vorgehaltenen Endoskopie-Systems mit 2 Einweg-Endoskopie-Systemen der Firma Ambu und Karl Storz …

Abstract P2-05-04: Gene expression associated with poor prognosis of young TNBC patients

Abstract Background: Among TNBC patients those of very young age (&amp;lt;40 years) display a significantly worse prognosis (Liedtke et al. 2013 Breast Cancer Res Treat). We verified this result in 1161 TNBC samples with full Affymetrix gene expression data of which 845 patients had both detailed age and follow up information. Materials and Methods: We split the full sample set into a finding cohort of 394 TNBC and a validation cohort of 767 TNBC encompassing 309 and 536 samples, respectively, with both age and follow up data. We then used significance analysis of microarrays (SAM) in the finding cohort to look for genes whose expression is associated with young age (&amp;lt;40 years). Iden…

Search for type-III seesaw heavy leptons inppcollisions ats=8  TeVwith the ATLAS detector

A search for the pair production of heavy leptons (N-0, L-+/-) predicted by the type-III seesaw theory formulated to explain the origin of small neutrino masses is presented. The decay channels N-0 -> W(+/-)l(+/-) (l = e, mu, tau) and L-+/- -> W(+/-)v (v = v(e), v(mu), v(tau)) are considered. The analysis is performed using the final state that contains two leptons (electrons or muons), two jets from a hadronically decaying W boson and large missing transverse momentum. The data used in the measurement correspond to an integrated luminosity of 20.3 fb(-1) of pp collisions at root s = 8 TeV collected by the ATLAS detector at the LHC. No evidence of heavy lepton pair production is observed. H…

Search for massive, long-lived particles using multitrack displaced vertices or displaced lepton pairs inppcollisions ats=8  TeVwith the ATLAS detector

Many extensions of the Standard Model posit the existence of heavy particles with long lifetimes. This article presents the results of a search for events containing at least one long-lived particle that decays at a significant distance from its production point into two leptons or into five or more charged particles. This analysis uses a data sample of proton-proton collisions at root s = 8 TeV corresponding to an integrated luminosity of 20.3 fb(-1) collected in 2012 by the ATLAS detector operating at the Large Hadron Collider. No events are observed in any of the signal regions, and limits are set on model parameters within supersymmetric scenarios involving R-parity violation, split sup…

Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma

Current treatment options for advanced and recurrent head and neck squamous cell carcinoma (HNSCC) enclose radiation and chemo-radiation approaches with or without surgery. While platinum-based chemotherapy regimens currently represent the gold standard in terms of efficacy and are given in the vast majority of cases, new chemotherapy regimens, namely immunotherapy are emerging. However, the response rates and therapy resistance mechanisms for either chemo regimen are hard to predict and remain insufficiently understood. Broad variations of chemo and radiation resistance mechanisms are known to date. This study describes the development of a standardized, high-throughput in vitro assay to a…

Resistance to Nano-Based Antifungals Is Mediated by Biomolecule Coronas.

Fungal infections are a growing global health and agricultural threat, and current chemical antifungals may induce various side-effects. Thus, nanoparticles are investigated as potential novel antifungals. We report that nanoparticles' antifungal activity strongly depends on their binding to fungal spores, focusing on the clinically important fungal pathogen Aspergillus fumigatus as well as common plant pathogens, such as Botrytis cinerea. We show that nanoparticle-spore complex formation was enhanced by the small nanoparticle size rather than the material, shape or charge, and could not be prevented by steric surface modifications. Fungal resistance to metal-based nanoparticles, such as Zn…

Search for displaced muonic lepton jets from light Higgs boson decay in proton–proton collisions at s=7 TeV with the ATLAS detector

A search is performed for collimated muon pairs displaced from the primary vertex produced in the decay of long-lived neutral particles in proton-proton collisions at root s = 7 TeV centre-of-mass ...

Search for excited leptons in proton-proton collisions ats=7  TeVwith the ATLAS detector

The ATLAS detector is used to search for excited leptons in the electromagnetic radiative decay channel l* -> l gamma. Results are presented based on the analysis of pp collisions at a center-of ...

Search for a Charged Higgs Boson Produced in the Vector-Boson Fusion Mode with DecayH±→W±ZusingppCollisions ats=8  TeVwith the ATLAS Experiment

A search for a charged Higgs boson, H-+/-, decaying to a W-+/- boson and a Z boson is presented. The search is based on 20.3 fb(-1) of proton-proton collision data at a center-of-mass energy of 8 TeV recorded with the ATLAS detector at the LHC. The H-+/- boson is assumed to be produced via vector-boson fusion and the decays W-+/- -> q (q') over bar and Z -> e(+)e(-)/mu(+)mu(-) are considered. The search is performed in a range of charged Higgs boson masses from 200 to 1000 GeV. No evidence for the production of an H+ boson is observed. Upper limits of 31-1020 fb at 95% C.L. are placed on the cross section for vector-boson fusion production of an H-+/- boson times its branching fraction to W…

Measurement of the b-hadron production cross section using decays to D⁎+μ−X final states in pp collisions at s=7 TeV with the ATLAS detector

The b-hadron production cross section is measured with the ATLAS detector in pp collisions at root s = 7 TeV, using 3.3 pb(-1) of integrated luminosity, collected during the 2010 LHC run. The b-had ...

ARIA digital anamorphosis: Digital transformation of health and care in airway diseases from research to practice: Review

Submitted by (omml@ubi.pt) on 2021-07-05T10:37:14Z No. of bitstreams: 1 2021_Bousquet J_A_Anamorphosis.pdf: 1897974 bytes, checksum: 918eb581ab4e940b055ef8514f960e28 (MD5) Approved for entry into archive by Pessoa (pfep@ubi.pt) on 2021-07-05T11:16:44Z (GMT) No. of bitstreams: 1 2021_Bousquet J_A_Anamorphosis.pdf: 1897974 bytes, checksum: 918eb581ab4e940b055ef8514f960e28 (MD5) Approved for entry into archive by Pessoa (pfep@ubi.pt) on 2021-07-05T11:20:07Z (GMT) No. of bitstreams: 1 2021_Bousquet J_A_Anamorphosis.pdf: 1897974 bytes, checksum: 918eb581ab4e940b055ef8514f960e28 (MD5) Made available in DSpace on 2021-07-05T11:20:07Z (GMT). No. of bitstreams: 1 2021_Bousquet J_A_Anamorphosis.pdf: …

Search for nonpointing photons in the diphoton andETmissfinal state ins=7  TeVproton-proton collisions using the ATLAS detector

A search has been performed for photons originating in the decay of a neutral long-lived particle, exploiting the capabilities of the ATLAS electromagnetic calorimeter to make precise measurements of the flight direction of photons, as well as the calorimeter's excellent time resolution. The search has been made in the diphoton plus missing transverse energy final state, using the full data sample of 4.8 fb(-1) of 7 TeV proton-proton collisions collected in 2011 with the ATLAS detector at the LHC. No excess is observed above the background expected from Standard Model processes. The results are used to set exclusion limits in the context of gauge mediated supersymmetry breaking models, with…

Measurements of the Nuclear Modification Factor for Jets inPb+PbCollisions atsNN=2.76  TeVwith the ATLAS Detector

Measurements of inclusive jet production are performed in pp and Pb+Pb collisions at √sNN = 2.76 TeV with the ATLAS detector at the LHC, corresponding to integrated luminosities of 4.0 pb−1 and 0.14 nb−1, respectively. The jets are identified with the anti-kt algorithm with R = 0.4, and the spectra are measured over the kinematic range of jet transverse momentum 32 < pT < 500 GeV, and absolute rapidity |y| < 2.1 and as a function of collision centrality. The nuclear modification factor, RAA, is evaluated and jets are found to be suppressed by approximately a factor of two in central collisions compared to pp collisions. The RAA shows a slight increase with pT and no significant variation wi…

Measurements of normalized differential cross sections fortt¯production inppcollisions at(s)=7  TeVusing the ATLAS detector

Measurements of normalized differential cross sections for top-quark pair production are presented as a function of the top-quark transverse momentum, and of the mass, transverse momentum, and rapidity of the t (t) over bar system, in proton proton collisions at a center-of-mass energy of root s = 7 TeV. The data set corresponds to an integrated luminosity of 4.6 fb(-1), recorded in 2011 with the ATLAS detector at the CERN Large Hadron Collider. Events are selected in the lepton jets channel, requiring exactly one lepton and at least four jets with at least one of the jets tagged as originating from a b-quark. The measured spectra are corrected for detector efficiency and resolution effects…

Search for Magnetic Monopoles ins=7  TeVppCollisions with the ATLAS Detector

This Letter presents a search for magnetic monopoles with the ATLAS detector at the CERN Large Hadron Collider using an integrated luminosity of 2.0 fb(-1) of pp collisions recorded at a center-of- ...

Underlying event characteristics and their dependence on jet size of charged-particle jet events inppcollisions at(s)=7  TeVwith the ATLAS detector

Distributions sensitive to the underlying event are studied in events containing one or more charged-particle jets produced in pp collisions at sqrt(s) = 7 TeV with the ATLAS detector at the Large Hadron Collider (LHC). These measurements reflect 800 inverse microbarns of data taken during 2010. Jets are reconstructed using the antikt algorithm with radius parameter R varying between 0.2 and 1.0. Distributions of the charged-particle multiplicity, the scalar sum of the transverse momentum of charged particles, and the average charged-particle pT are measured as functions of pT^JET in regions transverse to and opposite the leading jet for 4 GeV < pT^JET < 100 GeV. In addition, the R-dependen…

Cytotoxic and genotoxic effects of electronic cigarette liquids on human mucosal tissue cultures of the oropharynx

The popularity of electronic cigarettes (ECs) is rapidly growing and ECs are claimed to be an uncritically regarded alternative to conventional cigarettes. The mucosal tissue of the upper aerodigestive tract (UADT) is the first contact organ for xenobiotics such as liquids of ECs. The aim of this study is to investigate the bimolecular effects of e-liquids on human pharyngeal tissue cultures to evaluate whether e-liquids and their components present a risk factor for head and neck squamous cell carcinoma. Fresh tissue samples of healthy oropharyngeal mucosa were assembled into mucosal tissue cultures. Two fruit-flavored liquids (FLs), one tobacco-flavored liquid (TL) (all containing nicotin…

Determination of the Strange-Quark Density of the Proton from ATLAS Measurements of theW→ℓνandZ→ℓℓCross Sections

AQCD analysis is reported of ATLAS data on inclusive W-+/- and Z boson production in pp collisions at the LHC, jointly with ep deep-inelastic scattering data from HERA. The ATLAS data exhibit sensitivity to the light quark sea composition and magnitude at Bjorken x similar to 0:01. Specifically, the data support the hypothesis of a symmetric composition of the light quark sea at low x. The ratio of the strange-to-down sea quark distributions is determined to be 1:00(-0:28)(+0.25) at absolute four-momentum transfer squared Q(2) = 1: 9 GeV2 and x = 0: 023.

Search for Supersymmetry in Events with Three Leptons and Missing Transverse Momentum ins=7  TeVppCollisions with the ATLAS Detector

A search for the weak production of charginos and neutralinos decaying to a final state with three leptons (electrons or muons) and missing transverse momentum is presented. The analysis uses 2.06 fb(-1) of root s = 7 TeV proton-proton collision data delivered by the Large Hadron Collider and recorded with the ATLAS detector. Observations are consistent with standard model expectations in two signal regions that are either depleted or enriched in Z-boson decays. Upper limits at 95% confidence level are set in R-parity conserving phenomenological minimal supersymmetric and simplified models. For the simplified models, degenerate lightest chargino and next-to-lightest neutralino masses up to …

Control of dataset bias in combined Affymetrix cohorts of triple negative breast cancer

AbstractHeterogenous subtypes of breast cancer need to be analyzed separately. Pooling of datasets can provide reasonable sample sizes but dataset bias is an important concern. We assembled a combined dataset of 579 Affymetrix microarrays from triple negative breast cancer (TNBC) in Gene Expression Omnibus (GEO) series GSE31519. We developed a method for selecting comparable datasets and to control for the amount of dataset bias of individual probesets.

Search for scalar top quark pair production in natural gauge mediated supersymmetry models with the ATLAS detector in pp collisions at s=7 TeV

The results of a search for pair production of the lighter scalar partners of top quarks () in 2.05 fb−1 of pp collisions at TeV using the ATLAS experiment at the LHC are reported. Scalar top quar ...

Search for squarks and gluinos with the ATLAS detector in final states with jets and missing transverse momentum using4.7  fb−1ofs=7  TeVproton-proton collision data

A search for squarks and gluinos in final states containing jets, missing transverse momentum and no high-p(T) electrons or muons is presented. The data represent the complete sample recorded in 2011 by the ATLAS experiment in 7 TeV proton-proton collisions at the Large Hadron Collider, with a total integrated luminosity of 4.7 fb(-1). No excess above the Standard Model background expectation is observed. Gluino masses below 860 GeV and squark masses below 1320 GeV are excluded at the 95% confidence level in simplified models containing only squarks of the first two generations, a gluino octet and a massless neutralino, for squark or gluino masses below 2 TeV, respectively. Squarks and glui…

Search for a Supersymmetric Partner to the Top Quark in Final States with Jets and Missing Transverse Momentum ats=7  TeVwith the ATLAS Detector

A search for direct pair production of supersymmetric top squarks ((t) over tilde (1)) is presented, assuming the (t) over tilde (1) decays into a top quark and the lightest supersymmetric particle, (chi) over tilde (0)(1), and that both top quarks decay to purely hadronic final states. A total of 16 (4) events are observed compared to a predicted standard model background of 13.5(-3.6)(+3.7) (4.4(-1.3)(+1.7)) events in two signal regions based on integral Ldt = 4.7 fb(-1) of pp collision data taken at root s = 7 TeV with the ATLAS detector at the LHC. An exclusion region in the (t) over tilde (1) versus (chi) over tilde (0)(1) mass plane is evaluated: 370 1) 10) similar to 0 GeV while m((t…

Observation of a NewχbState in Radiative Transitions toΥ(1S)andΥ(2S)at ATLAS

The χb(nP) quarkonium states are produced in proton-proton collisions at the Large Hadron Collider at √s=7  TeV and recorded by the ATLAS detector. Using a data sample corresponding to an integrated luminosity of 4.4  fb-1, these states are reconstructed through their radiative decays to Υ(1S,2S) with Υ→μ+μ-. In addition to the mass peaks corresponding to the decay modes χb(1P,2P)→Υ(1S)γ, a new structure centered at a mass of 10.530±0.005(stat)±0.009(syst)  GeV is also observed, in both the Υ(1S)γ and Υ(2S)γ decay modes. This structure is interpreted as the χb(3P) system.

Magnetic Coupling in Y3Fe5O12/Gd3Fe5O12 Heterostructures

Ferrimagnetic ${\mathrm{Y}}_{3}{\mathrm{Fe}}_{5}{\mathrm{O}}_{12}$ (YIG) is the prototypical material for studying magnonic properties due to its exceptionally low damping. By substituting the yttrium with rare earth elements that have a net magnetic moment, we can introduce an additional spin degree of freedom. Here, we study the magnetic coupling in epitaxial ${\mathrm{Y}}_{3}{\mathrm{Fe}}_{5}{\mathrm{O}}_{12}$/${\mathrm{Gd}}_{3}{\mathrm{Fe}}_{5}{\mathrm{O}}_{12}$ (YIG/GIG) heterostructures grown by pulsed laser deposition. From bulk sensitive magnetometry and surface sensitive spin Seebeck effect and spin Hall magnetoresistance measurements, we determine the alignment of the heterostruct…

Search for new particles decaying to ZZ using final states with leptons and jets with the ATLAS detector in s=7 TeV proton–proton collisions

A search is presented for a narrow resonance decaying to a pair of Z bosons using data corresponding to 1.02 fb(-1) of integrated luminosity collected by the ATLAS experiment from pp collisions at ...

Effects of functional endoscopic sinus surgery on the acoustics of the sinonasal tract

Background: Nasal and paranasal cavities are supposed to contribute substantially to the vocal tract resonator properties. However, their acoustical effects as well as the effects of sinus surgery on the voice remain unclear. In this work we investigate resonance phenomena of paranasal sinuses prior to and after various rhinosurgical procedures in cadaveric human sinonasal tracts and corresponding 3D casts. Methodology: Nasal and paranasal cavities of formalin-preserved cadavers and corresponding 3D replicas were excited by sine tone sweeps from an earphone placed in the epipharynx.The response was picked up by a microphone at the nostrils. Different FESS procedures were performed and the a…

Measurement ofD*±meson production in jets fromppcollisions ats=7  TeVwith the ATLAS detector

This paper reports a measurement of D*(+/-) meson production in jets from proton- proton collisions at a center- of- mass energy of root s = 7 TeV at the CERN Large Hadron Collider. The measurement is based on a data sample recorded with the ATLAS detector with an integrated luminosity of 0.30 pb(-1) for jets with transverse momentum between 25 and 70 GeV in the pseudorapidity range vertical bar eta vertical bar D-0 pi(+), D-0 -> K-pi(+), and its charge conjugate. The production rate is found to be N(D*(+/-))/N(jet) = 0.025 +/- 0.001(stat.) +/- 0.004(syst.) for D*(+/-) mesons that carry a fraction z of the jet momentum in the range 0.3< z< 1. Monte Carlo predictions fail to describe the dat…

Harnessing Orbital-to-Spin Conversion of Interfacial Orbital Currents for Efficient Spin-Orbit Torques.

The system generates two errors of "Bad character(s) in field Abstract" for no reason. Please refer to the manuscript for the full abstract.

Search for high-mass resonances decaying to dilepton final states in pp collisions at √s = 7 TeV with the ATLAS detector

The ATLAS detector at the Large Hadron Collider is used to search for high-mass resonances decaying to an electron-positron pair or a muon-antimuon pair. The search is sensitive to heavy neutral Z′ gauge bosons, Randall-Sundrum gravitons, Z [superscript *] bosons, techni-mesons, Kaluza-Klein Z/γ bosons, and bosons predicted by Torsion models. Results are presented based on an analysis of pp collisions at a center-of-mass energy of 7 TeV corresponding to an integrated luminosity of 4.9 fb[superscript −1] in the e [superscript +] e [superscript −] channel and 5.0 fb[superscript −1] in the μ [superscript +] μ [superscript −] channel. A Z [superscript ′] boson with Standard Model-like couplings…

Search for Supersymmetry inppCollisions ats=7  TeVin Events with Two Photons and Missing Transverse Energy

A search for supersymmetry in the context of general gauge-mediated breaking with the lightest neutralino as the next-to-lightest supersymmetric particle and the gravitino as the lightest is presented. The data sample corresponds to an integrated luminosity of 36 pb(-1) recorded by the CMS experiment at the LHC. The search is performed by using events containing two or more isolated photons, at least one hadronic jet, and significant missing transverse energy. No excess of events at high missing transverse energy is observed. Upper limits on the signal cross section for general gauge-mediated supersymmetry between 0.3 and 1.1 pb at the 95% confidence level are determined for a range of squa…

Nanoparticle decoration impacts airborne fungal pathobiology

Airborne fungal pathogens, predominantly Aspergillus fumigatus, can cause severe respiratory tract diseases. Here we show that in environments, fungal spores can already be decorated with nanoparticles. Using representative controlled nanoparticle models, we demonstrate that various nanoparticles, but not microparticles, rapidly and stably associate with spores, without specific functionalization. Nanoparticle-spore complex formation was enhanced by small nanoparticle size rather than by material, charge, or "stealth" modifications and was concentration-dependently reduced by the formation of environmental or physiological biomolecule coronas. Assembly of nanoparticle-spore surface hybrid s…

Measurement of differentialJ/ψproduction cross sections and forward-backward ratios inp + Pbcollisions with the ATLAS detector

Measurements of differential cross sections for J/psi production in p + Pb collisions at root S-NN= 5.02 TeV at the CERN Large Hadron Collider with the ATLAS detector are presented. The data set us ...

Effects of cold atmospheric plasma (CAP) on bacteria and mucosa of the upper aerodigestive tract.

Abstract Objective Ear, nose and throat infections are among the most common reasons for absence from work. They are usually caused by various bacteria like Haemophilus influenzae, Staphylococcus aureus, Streptococcus pneumoniae and Streptococcus pyogenes. Cold atmospheric plasma (CAP) can effectively eliminate even multi-resistant bacteria and has no cytotoxic or mutagenic effects on the mucosa when applied for less than 60 s. Aim of the study was to evaluate the effects of CAP on common ENT bacteria and on the mucosa of the upper aerodigestive tract. Methods The bactericidal effects of CAP against the bacteria most commonly causing ENT infections were investigated using the colony-forming…

Monitoring and data quality assessment of the ATLAS liquid argon calorimeter

The liquid argon calorimeter is a key component of the ATLAS detector installed at the CERN Large Hadron Collider. The primary purpose of this calorimeter is the measurement of electron and photon kinematic properties. It also provides a crucial input for measuring jets and missing transverse momentum. An advanced data monitoring procedure was designed to quickly identify issues that would affect detector performance and ensure that only the best quality data are used for physics analysis. This article presents the validation procedure developed during the 2011 and 2012 LHC data-taking periods, in which more than 98% of the proton-proton luminosity recorded by ATLAS at a centre-of-mass ener…

Search for Scalar Bottom Quark Pair Production with the ATLAS Detector inppCollisions ats=7  TeV

The results of a search for pair production of the scalar partners of bottom quarks in 2: 05 fb(-1) of pp collisions at root s = 7 TeV using the ATLAS experiment are reported. Scalar bottom quarks ...

Measurement of inclusive jet and dijet production inppcollisions ats=7  TeVusing the ATLAS detector

Inclusive jet and dijet cross sections have been measured in proton-proton collisions at a centre-of-mass energy of 7 TeV using the ATLAS detector at the Large Hadron Collider. The cross sections were measured using jets clustered with the anti-kT algorithm with parameters R=0.4 and R=0.6. These measurements are based on the 2010 data sample, consisting of a total integrated luminosity of 37 inverse picobarns. Inclusive jet double-differential cross sections are presented as a function of jet transverse momentum, in bins of jet rapidity. Dijet double-differential cross sections are studied as a function of the dijet invariant mass, in bins of half the rapidity separation of the two leading …

Measurement of $ZZ$ production in $pp$ collisions at $\sqrt{s}=7$ TeV and limits on anomalous $ZZZ$ and $ZZ\gamma$ couplings with the ATLAS detector

Journal of High Energy Physics 2013.3 (2013): 128 reproduced by permission of Scuola Internazionale Superiore di Studi Avanzati (SISSA)

Electrical detection of the spin reorientation transition in antiferromagnetic TmFeO3 thin films by spin Hall magnetoresistance

$\mathrm{Tm}\mathrm{Fe}{\mathrm{O}}_{3}$ (TFO) is a canted antiferromagnet that undergoes a spin reorientation transition (SRT) with temperature between 82 and 94 K in single crystals. In this temperature region, the N\'eel vector continuously rotates from the crystallographic $c$ axis (below 82 K) to the $a$ axis (above 94 K). The SRT allows for a temperature control of distinct antiferromagnetic states without the need for a magnetic field, making it apt for applications working at terahertz frequencies. For device applications, thin films of TFO are required as well as an electrical technique for read-out of the magnetic state. Here, we demonstrate that orthorhombic TFO thin films can be…

Search for Pair Production of a Heavy Up-Type Quark Decaying to aWBoson and abQuark in thelepton+jetsChannel with the ATLAS Detector

A search is presented for production of a heavy up-type quark (t') together with its antiparticle, assuming subsequent decay to a W boson and a b quark, t'(t) over bar' -> W(+)bW(-)(b) over bar. The search is based on 1.04 fb(-1) of proton-proton collisions at root s = 7 TeV collected by the ATLAS detector at the CERN Large Hadron Collider. Data are analyzed in the lepton + jets final state, characterized by a high transverse momentum isolated electron or muon, high missing transverse momentum, and at least three jets. No significant excess of events above the background expectation is observed. A 95% C.L. lower limit of 404 GeV is set for the mass of the t' quark.

Ks0andΛproduction inppinteractions ats=0.9and 7 TeV measured with the ATLAS detector at the LHC

The production of K(S)(0) and Lambda hadrons is studied in pp collision data at root s = 0.9 and 7 TeV collected with the ATLAS detector at the LHC using a minimum-bias trigger. The observed distributions of transverse momentum, rapidity, and multiplicity are corrected to hadron level in a model-independent way within well-defined phase-space regions. The distribution of the production ratio of (Lambda) over bar to Lambda baryons is also measured. The results are compared with various Monte Carlo simulation models. Although most of these models agree with data to within 15% in the K(S)(0) distributions, substantial disagreements are found in the Lambda distributions of transverse momentum.

Search for the Standard Model Higgs boson in the decay channel H→ZZ(⁎)→4ℓ with 4.8 fb−1 of pp collision data at s=7 TeV with ATLAS

This Letter presents a search for the Standard Model Higgs boson in the decay channel H -> ZZ((*)) -> l(+)l(-)l(-)+l(')-, where l,l' = e or mu, using proton-proton collisions at root s = 7 TeV recorded with the ATLAS detector and corresponding to an integrated luminosity of 4.8 fb(-1). The four-lepton invariant mass distribution is compared with Standard Model background expectations to derive upper limits on the cross section of a Standard Model Higgs boson with a mass between 110 GeV and 600 GeV. The mass ranges 134-156 GeV, 182-233 GeV, 256-265 GeV and 268-415 GeV are excluded at the 95% confidence level. The largest upward deviations from the background-only hypothesis are observed for …

Search for high-mass diphoton resonances inppcollisions ats=8  TeVwith the ATLAS detector

Search for high-mass diphoton resonances in pp collisions at pffisffi root s=8 TeV with the ATLAS detector

Search for TeV-scale gravity signatures in final states with leptons and jets with the ATLAS detector at s=7 TeV

A search for physics beyond the Standard Model, in final states with at least one high transverse momentum charged lepton (electron or muon) and two additional high transverse momentum leptons or jets, is performed using 3.2 fb−1 of proton–proton collision data recorded by the ATLAS detector at the Large Hadron Collider in 2015 at √s = 13 TeV. The upper end of the distribution of the scalar sum of the transverse momenta of leptons and jets is sensitive to the production of high-mass objects. No excess of events beyond Standard Model predictions is observed. Exclusion limits are set for models of microscopic black holes with two to six extra dimensions.

Transition of laser-induced terahertz spin currents from torque- to conduction-electron-mediated transport

Spin transport is crucial for future spintronic devices operating at bandwidths up to the terahertz range. In F|N thin-film stacks made of a ferromagnetic/ferrimagnetic layer F and a normal-metal layer N, spin transport is mediated by (1) spin-polarized conduction electrons and/or (2) torque between electron spins. To identify a crossover from (1) to (2), we study laser-driven spin currents in F|Pt stacks where F consists of model materials with different degrees of electrical conductivity. For the magnetic insulators yttrium iron garnet, gadolinium iron garnet (GIG) and γ−Fe2O3, identical dynamics is observed. It arises from the terahertz interfacial spin Seebeck effect (SSE), is fully det…

Search for Quantum Black Hole Production in High-Invariant-MassLepton+JetFinal States UsingppCollisions ats=8  TeVand the ATLAS Detector

This Letter presents a search for quantum black-hole production using 20.3 fb(-1) of data collected with the ATLAS detector in pp collisions at the LHC at root s = 8 TeV. The quantum black holes are assumed to decay into a final state characterized by a lepton (electron or muon) and a jet. In either channel, no event with a lepton-jet invariant mass of 3.5 TeV or more is observed, consistent with the expected background. Limits are set on the product of cross sections and branching fractions for the lepton + jet final states of quantum black holes produced in a search region for invariant masses above 1 TeV. The combined 95% confidence level upper limit on this product for quantum black hol…

Search for Direct Top Squark Pair Production in Final States with One Isolated Lepton, Jets, and Missing Transverse Momentum ins=7  TeVppCollisions Using4.7  fb−1of ATLAS Data

A search is presented for direct top squark pair production in final states with one isolated electron or muon, jets, and missing transverse momentum in proton-proton collisions at root s = 7 TeV. The measurement is based on 4.7 fb(-1) of data collected with the ATLAS detector at the LHC. Each top squark is assumed to decay to a top quark and the lightest supersymmetric particle (LSP). The data are found to be consistent with standard model expectations. Top squark masses between 230 GeV and 440 GeV are excluded with 95% confidence for massless LSPs, and top squark masses around 400 GeV are excluded for LSP masses up to 125 GeV.

Targeting Cancer Chemotherapy Resistance by Precision Medicine-Driven Nanoparticle-Formulated Cisplatin.

Therapy resistance is the major cause of cancer death. As patients respond heterogeneously, precision/personalized medicine needs to be considered, including the application of nanoparticles (NPs). The success of therapeutic NPs requires to first identify clinically relevant resistance mechanisms and to define key players, followed by a rational design of biocompatible NPs capable to target resistance. Consequently, we employed a tiered experimental pipeline fromiin silico/ito analytical andiin vitro/ito overcome cisplatin resistance. First, we generated cisplatin-resistant cancer cells and used next-generation sequencing together with CRISPR/Cas9 knockout technology to identify the ion cha…

Reduction of olfactory sensitivity during normobaric hypoxia.

Abstract Objective Acute mountain sickness (AMS) is caused by a low partial pressure of oxygen and may occur above 2500 m. The aim of this research was to evaluate olfactory and gustatory abilities of healthy subjects during baseline conditions and after seven hours of normobaric hypoxia. Methods Sixteen healthy subjects were assessed using the Sniffin’ Sticks, as well as intensity and pleasantness ratings. Gustatory function was evaluated utilizing the Taste Strips. Experiments were carried out under baseline conditions (518 m altitude) followed by a second testing session after seven hours of normobaric hypoxia exposure (comparable to 4000 m altitude). Results During normobaric hypoxia ol…

Search for pair-produced heavy quarks decaying toWqin the two-lepton channel at(s)=7  TeVwith the ATLAS detector

A search is presented for heavy-quark pair production (Q (Q) over bar) under the decay hypothesis Q (Q) over bar -> W(+)qW(-)(q) over bar with q = d, s, b for up-type Q or q = u, c for down-type ...

Search for the Standard Model Higgs Boson in the Diphoton Decay Channel with4.9  fb−1ofppCollision Data ats=7  TeVwith ATLAS

A search for the standard model Higgs boson is performed in the diphoton decay channel. The data used correspond to an integrated luminosity of 4.9  fb-1 collected with the ATLAS detector at the Large Hadron Collider in proton-proton collisions at a center-of-mass energy of √s=7  TeV. In the diphoton mass range 110–150 GeV, the largest excess with respect to the background-only hypothesis is observed at 126.5 GeV, with a local significance of 2.8 standard deviations. Taking the look-elsewhere effect into account in the range 110–150 GeV, this significance becomes 1.5 standard deviations. The standard model Higgs boson is excluded at 95% confidence level in the mass ranges of 113–115 GeV and…

Dynamics of isolated-photon plus jet production in pp collisions at s=7 TeV with the ATLAS detector

The dynamics of isolated-photon plus jet production in pp collisions at a centre-of-mass energy of 7 TeV has been studied with the ATLAS detector at the LHC using an integrated luminosity of 37 pb( ...

Search for charged Higgs bosons through the violation of lepton universality in t(t)over-bar events using pp collision data at root s=7 TeV with the ATLAS experiment

In several extensions of the Standard Model, the top quark can decay into a bottom quark and a light charged Higgs boson H [superscript +], t → bH [superscript +], in addition to the Standard Model decay t → bW. Since W bosons decay to the three lepton generations equally, while H [superscript +] may predominantly decay into τν, charged Higgs bosons can be searched for using the violation of lepton universality in top quark decays. The analysis in this paper is based on 4.6 fb[superscript −1] of proton-proton collision data at √s = 7 TeV collected by the ATLAS experiment at the Large Hadron Collider. Signatures containing leptons (e or μ) and/or a hadronically decaying τ (τ [subscript had])…

Measurement of the production of neighbouring jets in lead–lead collisions at sNN=2.76 TeV with the ATLAS detector

This Letter presents measurements of correlated production of nearby jets in Pb+Pb collisions at root s(NN) = 2.76 TeV using the ATLAS detector at the Large Hadron Collider. The measurement was performed using 0.14 nb(-1)of data recorded in 2011. The production of correlated jet pairs was quantified using the rate, R-Delta R, of "neighbouring" jets that accompany "test" jets within a given range of angular distance, Delta R, in the pseudorapidity-azimuthal angle plane. The jets were measured in the ATLAS calorimeter and were reconstructed using the anti-ktalgorithm with radius parameters d = 0.2, 0.3, and 0.4. R-Delta R was measured in different Pb+Pbcollision centrality bins, characterized…

PD-L1 Expression and Immune Cell Infiltration in Gastroenteropancreatic (GEP) and Non-GEP Neuroendocrine Neoplasms With High Proliferative Activity

The potential of neuroendocrine neoplasms (NEN) to respond to checkpoint inhibitors is largely unknown and full of great expectations. Immunohistochemical (IHC) studies of programmed cell death ligand 1 (PD-L1) expression in the tumor microenvironment and its implications in predicting the response to checkpoint inhibition is a very active subject. Currently, the combined analysis of PD-L1 expression and tumor-associated immune cell (TAIC) infiltration is considered the best predictive marker of therapeutic response. Here we investigated the expression of PD-L1 on tumor cells (TC) and tumor-infiltrating immune cells (IC) by IHC in 68 NEN samples with a high proliferation rate (Ki-67 &gt;20%…

Centrality, rapidity, and transverse momentum dependence of isolated prompt photon production in lead-lead collisions atsNN=2.76TeV measured with the ATLAS detector

Prompt photon production in root S-NN = 2.76-TeV Pb + Pb collisions has been measured by the ATLAS experiment at the Large Hadron Collider using data collected in 2011 with an integrated luminosity ...

Measurement of the WW cross section in s=7 TeV pp collisions with the ATLAS detector and limits on anomalous gauge couplings

This Letter reports a measurement of the W W production cross section in root s = 7 TeV pp collisions using data corresponding to an integrated luminosity of 1.02 fb(-1) collected with the ATLAS de ...

Search for supersymmetry with jets, missing transverse momentum and at least one hadronically decaying τ lepton in proton–proton collisions at s=7 TeV with the ATLAS detector

A search for production of supersymmetric particles in final states containing jets, missing transverse momentum, and at least one hadronically decaying tau lepton is presented. The data were recor ...

Search for contact interactions in dilepton events from pp collisions at s=7 TeV with the ATLAS detector

This Letter presents a search for contact interactions in the dielectron and dimuon channels using data from proton-proton collisions produced by the LHC at,root s = 7 TeV and recorded by the ATLAS ...

Measurement with the ATLAS detector of multi-particle azimuthal correlations in p+Pb collisions at sNN=5.02 TeV

In order to study further the long-range correlations ("ridge") observed recently in p + Pb collisions at root s(NN) = 5.02 TeV, the second-order azimuthal anisotropy parameter ofcharged particles, ...