A general model for predicting the environmental impact of urban transportation

In this paper a generalised model is described for the analysis of the pollutant substances released in the atmosphere by urban transportation means. It essentially requires data referring to the running transportation fleet, year by year, that are generally on disposal of the local administrators through official data-bases. Pollutant emissions are here taken into account by means of the algorithms provided by the COPERT methodology, that applies to many European countries. The method, by means of a suitable statistical analysis of data concerning the running car fleet, allows also the definition of an useful indicator, that is the “yearly average vehicle”, that can be assumed as represent…

HPV infection in relation to OSCC histological grading and TNM stage. Evalutation by traditional statistics and fuzzy logic model

We aimed to evaluate if in oral squamous cell carcinoma (OSCC) there is a relationship between histological grading (HG), TNM clinical stage and HPV infection; and to study the performance of fuzzy logic compared to traditional statistics, in the analysis of HPV status and correlates of OSCC. In cross-sectional analysis, the study group comprised 63 patients (mean age 68.89 years (SD ± 11.78), range (32–93); males 28 (44.4%), females 35 (55.6%)) with OSCC histologically diagnosed. HPV-DNA was studied in exfoliated oral epithelial cells by nested PCR (MY09/MY11 and GP5+/GP6+ primers). Data were analysed in parallel by traditional statistics with multivariate analysis and a fuzzy logic (FL) t…

Diagnostic delay in oral squamous cell carcinoma: the role of cognitive and psychological variables

This retrospective study investigated, in two cohorts of subjects living in Southern Italy and awaiting treatment for oral squamous cell carcinoma (OSCC), the variables related to diagnostic delay ascribable to the patient, with particular reference to the cognitive and psychological ones. A total of 156 patients with OSCC (mean age: 62 years, M/F: 2.39∶1) were recruited at the Universities of Palermo and Naples. Risk factors related to patient delay included: sociodemographic, health-related, cognitive and psychological variables. The analysis was conducted by considering two different delay ranges: dichotomous (≤1 month vs. >1 month) and polytomous (3 months) delay. Data were investigated…

The control of indoor thermal comfort conditions: introducing a fuzzy adaptive controller

The control and the monitoring of indoor thermal conditions represents a pre-eminent task with the aim of ensuring suitable working and living spaces to people. Especially in industrialised countries, in fact, several rules and standards have been recently released in order of providing technicians with suitable design tools and effective indexes and parameters for the checking of the indoor microclimate. Among them, predicted mean vote (PMV) index is often adopted for assessing the thermal comfort conditions of thermal moderate environments. Unfortunately, the PMV index is characterised by non-linear features, that could determine some difficulties when monitoring and controlling HVAC equi…

Peri-Tumoral Inflammatory Cell Infiltration in OSCC: A Reliable Marker of Local Recurrence and Prognosis? An Investigation Using Artificial Neural Networks

The presence of inflammatory reaction in peri-tumoural connective tissue is generally considered as a defense mechanism against cancer, but inflammation tissue in malignant transformation and early steps of oncogenesis has been recently proven to play a supporting and aggravating role in some carcinomas. Aims of this retrospective study were to evaluate in OSCCs the independent association of peri-tumoral inflammatory infiltrate (PTI) with local recurrence (LR) or survival outcome, and to verify whether PTI can be considered a marker of prognosis. Data from 211 cases of OSCC, only surgically treated between 1990 and 2000, were collected and retrospectively analyzed for PTI and the event LR…

Risk factors of oral candidosis: a twofold approach of study by fuzzy logic and traditional statistic.

Abstract Objective To assess a panel of risk factors associated to oral candidosis (OC) onset and its chronic maintenance by means of fuzzy logic (FL) approach and statistical traditional methodology (STM); to investigate their casual relationship within a multifactorial framework. Design Case–control study. Setting One hospital-based clinic. Patients Eighty-nine patients with OC infection microbiologically diagnosed and 98 healthy subjects were consecutively recruited. Outcome measurements Anamnestic and clinical evaluations for OC, microbiological assessment (i.e. culture, CFU/mL counting and identification) were performed. The commonest predisposing factors for OC onset and its chronic s…

Neutron measurements for advanced nuclear systems: The n_TOF project at CERN

A few years ago, the neutron time-of-flight facility n_TOF was built at CERN to address some of the urgent needs of high-accuracy nuclear data for Accelerator Driven Systems and other advanced nuclear energy systems, as well as for nuclear astrophysics and fundamental nuclear physics. Thanks to the characteristics of the neutron beam, and to state-of-the-art detection and acquisition systems, high quality neutron cross-section data have been obtained for a variety of isotopes, many of which radioactive. Following an important upgrade of the spallation target and of the experimental area, a new measurement campaign has started last year. After a brief review of the most important results obt…

Evaluating human body area factors from digital images: A measurement tool for a better evaluation of the ergonomics of working places

The evaluation of comfort conditions of people in confined environments requires a knowledge of the human body's radiation data. This is essentially represented by the projected area of the body in a given direction. From this factor, other important parameters can be computed, such as projected area factors and angle factors. Presently, these parameters are evaluated using graphs deriving from a pioneering field study carried out by P.O. Fanger for which a piece of apparatus using mirrors and weight operations on film negatives is used. Obviously, these graphs, apart from referring to a limited number of subjects, also involve some reading errors. With the aim of enlarging the number of ex…

Expression of cell cycle markers and human papillomavirus infection in oral squamous cell carcinoma: use of fuzzy neural networks.

Our aim was to evaluate in oral squamous cell carcinoma (OSCC) the relationship between some cell cycle markers and HPV infection, conditionally to age, gender and certain habits of patients, and to assess the ability of fuzzy neural networks (FNNs) in building up an adequate predictive model based on logic inference rules. Eighteen cases of OSCC were examined by immunohistochemistry for MIB-1, PCNA and survivin expression; presence of HPV DNA was investigated in exfoliated oral mucosa cells by nested PCR (nPCR, MY09-MY11/GP5-GP6), and HPV genotype was determined by direct DNA sequencing. Data were analyzed by traditional statistics (TS) and FNNs. HPV DNA was found in 9/18 OSCCs (50.0 %) wi…

Haematological deficiencies in patients with recurrent aphthosis

Background  Recurrent aphthosis is a common oral ulcerative condition consisting also of a subset of similar ulcers, properly named ‘aphthous-like’ ulcers (ALU), linked to systemic diseases and among these, to iron, folic acid and vitamin B12 deficiencies. Objectives  The main objectives of this study were: (i) to evaluate the association between recurrent aphthosis and the most common predisposing factors; (ii) to assess the frequency of ALU in recurrent aphthosis; (iii) to verify the efficacy of a replacement therapy in all ALU patients. Methods  Thirty-two adults with recurrent aphthosis and 29 otherwise healthy controls were consecutively recruited, interviewed and subjected to haematol…

USE OF FUZZY NEURAL NETWORKS IN MODELING RELATIONSHIPS OF HPV INFECTION WITH APOPTOTIC AND PROLIFERATION MARKERS IN POTENTIALLY MALIGNANT ORAL LESIONS

To evaluate in oral leukoplakia the relationship between HPV infection and markers of apoptosis (bcl-2, survivin) and proliferation (PCNA), also conditionally to age, gender, smoking and drinking habits of patients, by means of Fuzzy neural networks (FNN) system 21 cases of oral leukopakia, clinically and histologically diagnosed, were examined for HPV DNA presence, bcl-2, survivin and PCNA expression. HPV DNA was investigated in exfoliated oral mucosa cells by nested PCR (nPCR: MY09-MY11/GP5-GP6), and the HPV genotype determined by direct DNA sequencing. All markers were investigated by means of standardised immunohistochemistry procedure. Data were analysed by chi-square test, crude OR an…

Oral pathology in untreated coeliac disease

Approaching the whole quality of buildings: methods for the evaluation of economic, energetic and environmental issues

In this work the energy, economy and environment ("three E") requirements for buildings are approached in a joint view, by means of an application to an example building typical of the Italian building stock. With this aim, the rate of involvement of renewable sources is here considered for linking energy and environmental characteristics. Economic and environmental features are joint by means of the evaluation of the cost of the saved CO2. Economic and energy characteristics are linked by means of the cost of the saved energy. In turn, the environmental ambit is addressed by means of the ecoprofile methodology and of the environmental labelling of buildings. This should lead toward a first…

Comparing different control strategies for indoor thermal comfort aimed at the evaluation of the energy cost of quality of building

Abstract The rapid improvement in the standard of living requires more detailed and sophisticated methods of evaluating comfort conditions. But, maintaining thermal comfort conditions in confined environments may require complex regulation procedures and the proper management of heating, ventilating and air conditioning (HVAC) systems. In turn, the requirements for indoor thermal comfort do not necessarily coincide with those of energy saving purposes, which in the last years are becoming a crucial issue owing to the enactment of the European Energy Performance of Buildings Directive (EPBD). The aim of this work is to compare different indoor control thermal comfort strategies in view of th…

First evidence of multiple β-delayed neutron emission for isotopes with a > 100

The β-delayed neutron emission probability, Pn, of very neutron-rich nuclei allows us to achieve a better understanding of the nuclear structure above the neutron separation energy, Sn. The emission of neutrons can become the dominant decay process in neutron-rich astrophysical phenomena such as the rapid neutron capture process (r-process). There are around 600 accessible isotopes for which β-delayed one-neutron emission (β1n) is energetically allowed, but the branching ratio has only been determined for about one third of them. β1n decays have been experimentally measured up to the mass A ∼ 150, plus a single measurement of 210Tl. Concerning two-neutron emitters (β2n), ∼ 300 isotopes are …

Measurement of the n-TOF beam profile with a micromegas detector

A Micromegas detector was used in the neutron Time-Of-Flight (n_TOF) facility at CERN to evaluate the spatial distribution of the neutron beam as a function of its kinetic energy. This was achieved over a large range of neutron energies by using two complementary processes: at low energy by capture of a neutron via the 6Li(n,[alpha])t reaction, and at high energy by elastic scattering of neutrons on gas nuclei (argon+isobutane or helium+isobutane). Data are compared to Monte Carlo simulations and an analytic function fitting the beam profile has been calculated with a sufficient precision to use in neutron capture experiments at the n_TOF facility. http://www.sciencedirect.com/science/artic…

Forecasting noise levels by means of neural networks for assessing urban traffic policies

Within the assessment of the sustainability of plans and actions concerning the built environment, the transportation sector plays an increasing role, due to its importance in the economic and social life of countries. As that, the analysis of the sustainability concerning the transportation sector is now often embodied into the so called Strategic Environmental Analyses (SEA), that should provide local administrators with easy criteria for ranking the environmental suitability of designing policies, and that would seem to encounter the needed features for a correct evaluation of the urban masterplan. The urban noise forecast is very useful for local administrations, which have presently to…

Measurements of projected areas of seated and standing people of southern Italy based on a statistical analysis

One of the most important components affecting the human thermal balance is represented by its radiative exchange with the surrounding surfaces. The projected area of the human body is an important parameter of these thermal exchanges. Unfortunately, although the anthropometric measures of people are characterized by significant differences among various populations, the experimental data currently available in the literature refers to a small group of people. Moreover, measurements are generally performed regardless of the statistical significance of the involved subjects with respect to the population to which they belong. In this study, a statistical study is introduced that is based on …