0000000000133664
AUTHOR
Nathalie Franceschi
Variation and covariation in infectivity, virulence and immunodepression in the host-parasite association Gammarus pulex-Pomphorhynchus laevis.
Parasites often manipulate host immunity for their own benefit, either by exacerbating or suppressing the immune response and this may directly affect the expression of parasite virulence. However, genetic variation in immunodepression, which is a prerequisite to its evolution, and the relationship between immunodepression and virulence, have rarely been studied. Here, we investigated the variation among sibships of the acanthocephalan parasite, Pomphorhynchus laevis , in infecting and in immunodepressing its amphipod host, Gammarus pulex . We also assessed the covariation between infectivity, parasite-induced immune depression and host mortality (parasite virulence). We found that infecti…
Size-assortative pairing in Gammarus pulex (Crustacea: Amphipoda): a test of the prudent choice hypothesis.
6 pages; International audience; Positive assortative mating is a widespread phenomenon in the animal kingdom. Several hypotheses have been proposed to explain this reproductive pattern in natural populations, but growing evidence suggests that assortative mating most often results from sexual mating preferences. Recently, conditiondependent mate choice in the face of costly competition for mates has been proposed to explain assortative mating in natural populations. Variation in competitive ability may generate variation in both the strength and the direction of mate preference, resulting in assortative mating with respect to individual quality if low-quality competitors are less choosy, o…
Intraspecific variability in host manipulation by parasites
8 pages; International audience; Manipulative parasites have the capacity to alter a broad range of phenotypic traits in their hosts, extending from colour, morphology and behaviour. While significant attention has been devoted to describing the diversity of host manipulation among parasite clades, and testing the adaptive value of phenotypic traits that can be manipulated, there is increasing evidence that variation exists in the frequency and intensity of the changes displayed by parasitized individuals within single host-manipulative parasite systems. Such variability occurs within individuals, between individuals of a same population, and across populations. Here we review the non-genet…
Co-variation between the intensity of behavioural manipulation and parasite development time in an acanthocephalan-amphipod system.
8 pages; International audience; Pomphorhynchus laevis, a fish acanthocephalan parasite, manipulates the behaviour of its gammarid intermediate host to increase its trophic transmission to the definitive host. However, the intensity of behavioural manipulation is variable between individual gammarids and between parasite populations. To elucidate causes of this variability, we compared the level of phototaxis alteration induced by different parasite sibships from one population, using experimental infections of Gammarus pulex by P. laevis. We used a naive gammarid population, and we carried out our experiments in two steps, during spring and winter. Moreover, we also investigated co-variati…
Immune depression induced by acanthocephalan parasites in their intermediate crustacean host: consequences for the risk of super-infection and links with host behavioural manipulation.
9 pages; International audience; Parasite survival in hosts mainly depends on the capacity to circumvent the host immune response. Acanthocephalan infections in gammarids are linked with decreased activity of the prophenoloxidase (ProPO) system, suggesting an active immunosuppression process. Nevertheless, experimental evidence for this hypothesis is lacking: whether these parasites affect several immune pathways is unknown and the consequences of such immune change have not been investigated. In particular, the consequences for other pathogens are not known; neither are the links with other parasite-induced manipulations of the host. Firstly, using experimental infections of Pomphorhynchus…
Larval size in acanthocephalan parasites : Influence of intraspecific competition and effects on intermediate host behavioural changes
Abstract Background Parasites often face a trade-off between exploitation of host resources and transmission probabilities to the next host. In helminths, larval growth, a major component of adult parasite fitness, is linked to exploitation of intermediate host resources and is influenced by the presence of co-infecting conspecifics. In manipulative parasites, larval growth strategy could also interact with their ability to alter intermediate host phenotype and influence parasite transmission. Methods We used experimental infections of Gammarus pulex by Pomphorhynchus laevis (Acanthocephala), to investigate larval size effects on host behavioural manipulation among different parasite sibshi…
VARIATION BETWEEN POPULATIONS AND LOCAL ADAPTATION IN ACANTHOCEPHALAN-INDUCED PARASITE MANIPULATION
Many trophically transmitted parasites manipulate their intermediate host phenotype, resulting in higher transmission to the final host. However, it is not known if manipulation is a fixed adaptation of the parasite or a dynamic process upon which selection still acts. In particular, local adaptation has never been tested in manipulating parasites. In this study, using experimental infections between six populations of the acanthocephalan parasite Pomphorhynchus laevis and its amphipod host Gammarus pulex, we investigated whether a manipulative parasite may be locally adapted to its host. We compared adaptation patterns for infectivity and manipulative ability. We first found a negative eff…
The effects of parasite age and intensity on variability in acanthocephalan-induced behavioural manipulation.
10 pages; International audience; Numerous parasites with complex life cycles are able to manipulate the behaviour of their intermediate host in a way that increases their trophic transmission to the definitive host. Pomphorhynchus laevis, an acanthocephalan parasite, is known to reverse the phototactic behaviour of its amphipod intermediate host, Gammarus pulex, leading to an increased predation by fish hosts. However, levels of behavioural manipulation exhibited by naturally-infected gammarids are extremely variable, with some individuals being strongly manipulated whilst others are almost not affected by infection. To investigate parasite age and parasite intensity as potential sources o…
Behavioural and physiological effects of the trophically transmitted cestode parasite, Cyathocephalus truncatus, on its intermediate host, Gammarus pulex
SUMMARYSome parasites with complex life-cycles are able to manipulate the behaviour of their intermediate hosts in a way that increases their transmission to the next host. Gammarids infected by the tapeworm Cyathocephalus truncatus (Cestoda: Spathebothriidea) are known to be more predated by fish than uninfected ones, but potential behavioural manipulation by the parasite has never been investigated. In this study, we tested the hypothesis that C. truncatus is able to manipulate the behaviour of one of its intermediate hosts, Gammarus pulex (Crustacea: Amphipoda). To assess if any behavioural change was linked to other phenotypic alterations, we also measured the immunity of infected and u…