0000000000148588

AUTHOR

M. Vargas

showing 19 related works from this author

Excess electronic recoil events in XENON1T

2020

We report results from searches for new physics with low-energy electronic recoil data recorded with the XENON1T detector. With an exposure of 0.65 t-y and an unprecedentedly low background rate of $76\pm2$ events/(t y keV) between 1 and 30 keV, the data enables sensitive searches for solar axions, an enhanced neutrino magnetic moment, and bosonic dark matter. An excess over known backgrounds is observed at low energies and most prominent between 2 and 3 keV. The solar axion model has a 3.4$\sigma$ significance, and a 3D 90% confidence surface is reported for axion couplings to electrons, photons, and nucleons. This surface is inscribed in the cuboid defined by $g_{ae}<3.8 \times 10^{-12}$,…

xenon: targetaxionssolar axionmagnetic momentdimension: 3neutrino: solarPhysics beyond the Standard ModelSolar neutrinodark matter: direct detection01 natural sciences7. Clean energyHigh Energy Physics - ExperimentDark matter direct detection axionHigh Energy Physics - Experiment (hep-ex)neutrinoXENONHigh Energy Physics - Phenomenology (hep-ph)background: lowRecoilelectron: recoil[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]beta-raysParticle Physics Experimentscoupling: (axion 2electron)multi-purpose particle detectornuclear instrumentationComputingMilieux_MISCELLANEOUSinstrumentationPhysicsxenon: liquidboson: dark matteraxion 2nucleontritiumnew physics: search forsemileptonic decayboson: vectortensionneutrino: magnetic momentHigh Energy Physics - Phenomenologyaxion 2photonlow backgroundbosonNeutrinoionizing radiationNucleonAstrophysics - Cosmology and Nongalactic AstrophysicsCosmology and Nongalactic Astrophysics (astro-ph.CO)dark matter detectorelectronic recoilElectron captureXENON1T detectorDark matterlow-energy electronic recoil dataFOS: Physical sciences[PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex]dark matterNONuclear physicsPE2_2PE2_1tritium: semileptonic decay0103 physical sciencessolar axion modelsurface[PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det]axion: couplingPE2_4010306 general physicspseudoscalarAxiondark matter: vectordark matter XENON1T detector electronic recoilsolar neutrinodetectorDark Matter Axions Beta Decay Liquid Xenon TPC010308 nuclear & particles physicsaxion 2electroncoupling: (axion 2nucleon)dark matter: detectormodel: axionGran Sassometrology[PHYS.HPHE]Physics [physics]/High Energy Physics - Phenomenology [hep-ph]axionstellar constraintscoupling: (axion 2photon)High Energy Physics::Experimentparticle dark matterdirect detectionbeta decayaxion: solar[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]experimental results
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Search for Coherent Elastic Scattering of Solar B8 Neutrinos in the XENON1T Dark Matter Experiment

2021

We report on a search for nuclear recoil signals from solar $^8$B neutrinos elastically scattering off xenon nuclei in XENON1T data, lowering the energy threshold from 2.6 keV to 1.6 keV. We develop a variety of novel techniques to limit the resulting increase in backgrounds near the threshold. No significant $^8$B neutrino-like excess is found in an exposure of 0.6 t $\times$ y. For the first time, we use the non-detection of solar neutrinos to constrain the light yield from 1-2 keV nuclear recoils in liquid xenon, as well as non-standard neutrino-quark interactions. Finally, we improve upon world-leading constraints on dark matter-nucleus interactions for dark matter masses between 3 GeV/…

Elastic scatteringPhysicsPhysics::Instrumentation and DetectorsScatteringAstrophysics::High Energy Astrophysical PhenomenaSolar neutrinoDark matterGeneral Physics and Astronomychemistry.chemical_element01 natural sciences7. Clean energyNuclear physicsXenonRecoilchemistry0103 physical sciencesHigh Energy Physics::ExperimentNeutrinoNuclear Experiment010306 general physicsOrder of magnitudePhysical Review Letters
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Search for inelastic scattering of WIMP dark matter in XENON1T

2021

We report the results of a search for the inelastic scattering of weakly interacting massive particles (WIMPs) in the XENON1T dark matter experiment. Scattering off $^{129}$Xe is the most sensitive probe of inelastic WIMP interactions, with a signature of a 39.6 keV de-excitation photon detected simultaneously with the nuclear recoil. Using an exposure of 0.89 tonne-years, we find no evidence of inelastic WIMP scattering with a significance of more than 2$\sigma$. A profile-likelihood ratio analysis is used to set upper limits on the cross-section of WIMP-nucleus interactions. We exclude new parameter space for WIMPs heavier than 100 GeV/c${}^2$, with the strongest upper limit of $3.3 \time…

xenon: targetPhotonPhysics::Instrumentation and DetectorsParameter space01 natural sciencesWIMP: dark matterHigh Energy Physics - Experiment; High Energy Physics - Experiment; astro-ph.COHigh Energy Physics - ExperimentHigh Energy Physics - Experiment (hep-ex)XENONRecoilWIMPWIMP nucleus: cross section[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Dark Matterparameter spaceNuclear ExperimentComputingMilieux_MISCELLANEOUSnucleus: recoilPhysicsDark Matter Inelastic scattering XENON Direct Dark MatterPhysicsphotonAstrophysics::Instrumentation and Methods for AstrophysicsDirect Dark MatterWeakly interacting massive particlesastro-ph.COsignatureAstrophysics - Cosmology and Nongalactic AstrophysicsParticle physicsInelastic scatteringCosmology and Nongalactic Astrophysics (astro-ph.CO)Dark matterFOS: Physical sciencesWIMP: massAstrophysics::Cosmology and Extragalactic AstrophysicsInelastic scatteringNOPE2_2PE2_10103 physical sciencesddc:530010306 general physics010308 nuclear & particles physicsScatteringWIMP nucleus: interactionDarkmatterWIMP: interactionHigh Energy Physics::Experiment[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]Astrophysics and astroparticle physicsexperimental resultsPhysical Review D. Particles, Fields, Gravitation, and Cosmology
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Light Dark Matter Search with Ionization Signals in XENON1T

2019

We report constraints on light dark matter (DM) models using ionization signals in the XENON1T experiment. We mitigate backgrounds with strong event selections, rather than requiring a scintillation signal, leaving an effective exposure of (22±3) tonne day. Above ∼0.4 keVee, we observe &lt;1 event/(tonne day keVee), which is more than 1000 times lower than in similar searches with other detectors. Despite observing a higher rate at lower energies, no DM or CEvNS detection may be claimed because we cannot model all of our backgrounds. We thus exclude new regions in the parameter spaces for DM-nucleus scattering for DM masses mχ within 3–6 GeV/c2, DM-electron scattering for mχ&gt;30 MeV/c2, a…

Light Dark Matter TPC Ionization Axion-Like particlesCosmology and Nongalactic Astrophysics (astro-ph.CO)PhotonFOS: Physical sciencesGeneral Physics and AstronomyS030DI5S029AECAstrophysics01 natural sciencesHigh Energy Physics - ExperimentHigh Energy Physics - Experiment (hep-ex)S030DE5Ionization0103 physical sciencesionization[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]010306 general physicsAbsorption (electromagnetic radiation)Light dark matterscintillation counterPhysicsDark Matter WIMP Dark-Matter detectors Time-projection chamber detectorsScintillationScatteringbackgrounddark matter: massphotonscatteringS029HPHS030DN5* Automatic Keywords *Scintillation counterElementary Particles and Fieldsaxion-like particles[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]Event (particle physics)absorptionAstrophysics - Cosmology and Nongalactic Astrophysics
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XENON1T Dark Matter Data Analysis: Signal Reconstruction, Calibration and Event Selection

2019

The XENON1T experiment at the Laboratori Nazionali del Gran Sasso is the most sensitive direct detection experiment for dark matter in the form of weakly interacting particles (WIMPs) with masses above $6\,$GeV/$c^2$ scattering off nuclei. The detector employs a dual-phase time projection chamber with 2.0 metric tons of liquid xenon in the target. A one metric $\mathrm{ton}\times\mathrm{year}$ exposure of science data was collected between October 2016 and February 2018. This article reports on the performance of the detector during this period and describes details of the data analysis that led to the most stringent exclusion limits on various WIMP-nucleon interaction models to date. In pa…

xenon: targetWIMP nucleon: interactiondata analysis methodPhysics - Instrumentation and Detectorsinteraction: modelPhysics::Instrumentation and DetectorsDark matterchemistry.chemical_elementFOS: Physical sciencesdark matter: direct detection01 natural sciencesHigh Energy Physics - ExperimentNuclear physicsHigh Energy Physics - Experiment (hep-ex)XENONXenon0103 physical sciencesCalibration[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Dark MatterParticle Physics Experiments[PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det]010306 general physicsNuclear ExperimentDark Matter Direct Search Signal reconstruction calibratiuonPhysicsxenon: liquidTime projection chamber010308 nuclear & particles physicsScatteringSignal reconstructionDetectorAstrophysics::Instrumentation and Methods for AstrophysicsInstrumentation and Detectors (physics.ins-det)calibrationtime projection chamberEvent selectionchemistryHigh Energy Physics::Experimentperformance
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$^{222}$Rn emanation measurements for the XENON1T experiment

2021

The selection of low-radioactive construction materials is of utmost importance for the success of low-energy rare event search experiments. Besides radioactive contaminants in the bulk, the emanation of radioactive radon atoms from material surfaces attains increasing relevance in the effort to further reduce the background of such experiments. In this work, we present the $^{222}$Rn emanation measurements performed for the XENON1T dark matter experiment. Together with the bulk impurity screening campaign, the results enabled us to select the radio-purest construction materials, targeting a $^{222}$Rn activity concentration of 10 $\mu$Bq/kg in 3.2 t of xenon. The knowledge of the distribut…

Physics - Instrumentation and DetectorsPhysics and Astronomy (miscellaneous)Radon emanationFOS: Physical scienceschemistry.chemical_element01 natural sciencesNOHigh Energy Physics - Experimentradon: nuclideHigh Energy Physics - Experiment (hep-ex)XENONXenon222 RnPE2_2PE2_10103 physical sciencesActivity concentration[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Dark Matter[PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det]010306 general physicsEngineering (miscellaneous)background: radioactivityPhysicsradon: admixture010308 nuclear & particles physicsdetector: surfacescreeningInstrumentation and Detectors (physics.ins-det)chemistryXenon Dark matter 222 Rn radioactivityDark Matter Radon emanation XENON Direct Dark MatterDirect Dark MatterradioactivityAtomic physics
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The XENON1T Dark Matter Experiment

2017

The XENON1T experiment at the Laboratori Nazionali del Gran Sasso (LNGS) is the first WIMP dark matter detector operating with a liquid xenon target mass above the ton-scale. Out of its 3.2 t liquid xenon inventory, 2.0 t constitute the active target of the dual-phase time projection chamber. The scintillation and ionization signals from particle interactions are detected with low-background photomultipliers. This article describes the XENON1T instrument and its subsystems as well as strategies to achieve an unprecedented low background level. First results on the detector response and the performance of the subsystems are also presented. © 2017, The Author(s).

xenon: targetPhotomultiplierCosmology and Nongalactic Astrophysics (astro-ph.CO)Physics - Instrumentation and DetectorsPhysics and Astronomy (miscellaneous)WIMP[ PHYS.ASTR ] Physics [physics]/Astrophysics [astro-ph]Dark matterchemistry.chemical_elementFOS: Physical scienceslcsh:Astrophysics01 natural sciencesHigh Energy Physics - ExperimentNuclear physicsHigh Energy Physics - Experiment (hep-ex)XENONXenonbackground: lowWIMP[ PHYS.HEXP ] Physics [physics]/High Energy Physics - Experiment [hep-ex]Ionization0103 physical scienceslcsh:QB460-466[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Dark Matterlcsh:Nuclear and particle physics. Atomic energy. Radioactivity[PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det]010306 general physicsEngineering (miscellaneous)Instrumentation and Methods for Astrophysics (astro-ph.IM)[ PHYS.PHYS.PHYS-INS-DET ] Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det]AstrophysiquePhysicsScintillationxenon: liquidTime projection chamberphotomultiplier010308 nuclear & particles physicsDetectorInstrumentation and Detectors (physics.ins-det)dark matter: detectortime projection chamberchemistrylcsh:QC770-798TPCAstrophysics - Instrumentation and Methods for Astrophysics[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]performanceAstrophysics - Cosmology and Nongalactic AstrophysicsEuropean Physical Journal C
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Search for Light Dark Matter Interactions Enhanced by the Migdal Effect or Bremsstrahlung in XENON1T.

2019

Direct dark matter detection experiments based on a liquid xenon target are leading the search for dark matter particles with masses above ∼5 GeV/c2, but have limited sensitivity to lighter masses because of the small momentum transfer in dark matter-nucleus elastic scattering. However, there is an irreducible contribution from inelastic processes accompanying the elastic scattering, which leads to the excitation and ionization of the recoiling atom (the Migdal effect) or the emission of a bremsstrahlung photon. In this Letter, we report on a probe of low-mass dark matter with masses down to about 85 MeV/c2 by looking for electronic recoils induced by the Migdal effect and bremsstrahlung us…

xenon: targetPhysics - Instrumentation and Detectorsdark matter: interactionelastic scatteringGeneral Physics and Astronomy01 natural sciencesHigh Energy Physics - ExperimentHigh Energy Physics - Experiment (hep-ex)XenonIonizationexcited state[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Nuclear ExperimentLight dark matterElastic scatteringPhysicsxenon: liquidatommomentum transferMomentum transferBremsstrahlungInstrumentation and Detectors (physics.ins-det)photon: bremsstrahlungS030DN5Weakly interacting massive particlesExcited stateAstrophysics - Cosmology and Nongalactic AstrophysicsCosmology and Nongalactic Astrophysics (astro-ph.CO)Dark matterLight Dark Matter Direct search Liquid Xenon TPCFOS: Physical sciencesS030DI5chemistry.chemical_elementNuclear physicsParticle dark matterrecoilionization0103 physical sciencesDark matter[PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det]010306 general physicsscintillation counterS030DP5010308 nuclear & particles physicsdown: masssensitivityDark matter Particle dark matter Weakly interacting massive particles* Automatic Keywords *chemistryElementary Particles and Fieldsbremsstrahlung: emission[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]Physical review letters
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Projected WIMP sensitivity of the XENONnT dark matter experiment

2020

XENONnT is a dark matter direct detection experiment, utilizing 5.9 t of instrumented liquid xenon, located at the INFN Laboratori Nazionali del Gran Sasso. In this work, we predict the experimental background and project the sensitivity of XENONnT to the detection of weakly interacting massive particles (WIMPs). The expected average differential background rate in the energy region of interest, corresponding to (1, 13) keV and (4, 50) keV for electronic and nuclear recoils, amounts to 12.3 ± 0.6 (keV t y)-1 and (2.2± 0.5)× 10−3 (keV t y)-1, respectively, in a 4 t fiducial mass. We compute unified confidence intervals using the profile construction method, in order to ensure proper coverage…

WIMP nucleon: scatteringdata analysis methodCosmology and Nongalactic Astrophysics (astro-ph.CO)Physics - Instrumentation and DetectorsHadronDark matterFOS: Physical sciencesElementary particledark matter: direct detection01 natural sciencesWIMP: dark matterHigh Energy Physics - ExperimentNONuclear physicsHigh Energy Physics - Experiment (hep-ex)XENONPE2_2WIMPPE2_1electron: recoil0103 physical sciences[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Neutron[PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det]010306 general physicsPE2_4Dark matter experimentComputingMilieux_MISCELLANEOUSactivity reportnucleus: recoilPhysicsxenon: liquid010308 nuclear & particles physicsbackgroundAstronomy and AstrophysicsInstrumentation and Detectors (physics.ins-det)Dark matter experiments dark matter simulationssensitivityBaryonDark matter experimentsDark matter simulationsWeakly interacting massive particlesDark matter experiments; Dark matter simulationsNucleon[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]Astrophysics - Cosmology and Nongalactic AstrophysicsJournal of Cosmology and Astroparticle Physics
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Effective field theory search for high-energy nuclear recoils using the XENON100 dark matter detector

2017

International audience; We report on weakly interacting massive particles (WIMPs) search results in the XENON100 detector using a nonrelativistic effective field theory approach. The data from science run II (34  kg×224.6 live days) were reanalyzed, with an increased recoil energy interval compared to previous analyses, ranging from (6.6–240)  keVnr. The data are found to be compatible with the background-only hypothesis. We present 90% confidence level exclusion limits on the coupling constants of WIMP-nucleon effective operators using a binned profile likelihood method. We also consider the case of inelastic WIMP scattering, where incident WIMPs may up-scatter to a higher mass state, and …

WIMP nucleon: scatteringParticle physicsdata analysis methodCosmology and Nongalactic Astrophysics (astro-ph.CO)Physics and Astronomy (miscellaneous)Physics::Instrumentation and DetectorsWIMP[ PHYS.ASTR ] Physics [physics]/Astrophysics [astro-ph]Dark matterchemistry.chemical_elementFOS: Physical sciencesAstrophysics::Cosmology and Extragalactic Astrophysics01 natural sciencesNuclear physicsXENONXenonWIMPstatistical analysis0103 physical sciencesEffective field theoryDark Matter010306 general physicsS030UDMnucleus: recoilPhysicsCoupling constanteffective field theory: nonrelativistic010308 nuclear & particles physicsScatteringDetectorAstrophysics::Instrumentation and Methods for Astrophysicsdark matter: detectorchemistryWeakly interacting massive particlesDirect SearchHigh Energy Physics::ExperimentTPC[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]recoil: energyAstrophysics - Cosmology and Nongalactic Astrophysics
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Intrinsic backgrounds from Rn and Kr in the XENON100 experiment

2018

In this paper, we describe the XENON100 data analyses used to assess the target-intrinsic background sources radon ([InlineMediaObject not available: see fulltext.]), thoron ([InlineMediaObject not available: see fulltext.]) and krypton ([InlineMediaObject not available: see fulltext.]). We detail the event selections of high-energy alpha particles and decay-specific delayed coincidences. We derive distributions of the individual radionuclides inside the detector and quantify their abundances during the main three science runs of the experiment over a period of ∼4years, from January 2010 to January 2014. We compare our results to external measurements of radon emanation and krypton concentr…

data analysis methodPhysics - Instrumentation and DetectorsPhysics and Astronomy (miscellaneous)WIMPFOS: Physical scienceschemistry.chemical_elementlcsh:AstrophysicsRadonSciences de l'ingénieur01 natural sciencesIonNuclear physicsradon: nuclideXENONlcsh:QB460-4660103 physical scienceslcsh:Nuclear and particle physics. Atomic energy. Radioactivity[PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det]010306 general physicsInstrumentation and Methods for Astrophysics (astro-ph.IM)[ PHYS.PHYS.PHYS-INS-DET ] Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det]Engineering (miscellaneous)nuclidebackground: radioactivitybackground: suppressionkryptonPhysicsRadionuclidePhysique010308 nuclear & particles physicsKryptonInstrumentation and Detectors (physics.ins-det)Alpha particleAstronomieDark Matter direct search experimentrespiratory tract diseasesRadon DaughtersBackgroundchemistrylcsh:QC770-798TPCAstrophysics - Instrumentation and Methods for Astrophysics
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Constraining the spin-dependent WIMP-nucleon cross sections with XENON1T

2019

We report the first experimental results on spin-dependent elastic weakly interacting massive particle (WIMP) nucleon scattering from the XENON1T dark matter search experiment. The analysis uses the full ton year exposure of XENON1T to constrain the spin-dependent proton-only and neutron-only cases. No significant signal excess is observed, and a profile likelihood ratio analysis is used to set exclusion limits on the WIMP-nucleon interactions. This includes the most stringent constraint to date on the WIMP-neutron cross section, with a minimum of 6.3 × 10−42 cm2 at 30 GeV/c2 and 90% confidence level. The results are compared with those from collider searches and used to exclude new paramet…

WIMP nucleon: interactionWIMP nucleon: scatteringParticle physicsCosmology and Nongalactic Astrophysics (astro-ph.CO)IsoscalarDark matterNuclear TheoryMassive particleGeneral Physics and AstronomyFOS: Physical sciencesParameter spacedark matter: direct detectionGravitation and Astrophysicsspin: dependence01 natural scienceslaw.inventionHigh Energy Physics - Phenomenology (hep-ph)WIMPlawisoscalar0103 physical sciencesS046DM1mediation010306 general physicsColliderPseudovectorPhysicsS030DN2S030DN1S030DP3S030DN3S030DP2S030DP1WIMP nucleon: cross sectionaxial-vectorHigh Energy Physics - PhenomenologyWIMPs Spin Dependent Cross Sections Neutron Cross Sections Likelihood methoddark matter: scattering[PHYS.HPHE]Physics [physics]/High Energy Physics - Phenomenology [hep-ph]High Energy Physics::ExperimentNucleon[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]Astrophysics - Cosmology and Nongalactic Astrophysicsexperimental results
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Human Immunodeficiency Virus Continuum of Care in 11 European Union Countries at the End of 2016 Overall and by Key Population: Have We Made Progress?

2020

Abstract Background High uptake of antiretroviral treatment (ART) is essential to reduce human immunodeficiency virus (HIV) transmission and related mortality; however, gaps in care exist. We aimed to construct the continuum of HIV care (CoC) in 2016 in 11 European Union (EU) countries, overall and by key population and sex. To estimate progress toward the Joint United Nations Programme on HIV/AIDS (UNAIDS) 90-90-90 target, we compared 2016 to 2013 estimates for the same countries, representing 73% of the population in the region. Methods A CoC with the following 4 stages was constructed: number of people living with HIV (PLHIV); proportion of PLHIV diagnosed; proportion of those diagnosed …

Male0301 basic medicinePsychological interventionHuman immunodeficiency virus (HIV)MedizinContinuum of care; Europe; HIV infection; Key population; Sex; Anti-Retroviral Agents; Continuity of Patient Care; European Union; HIV; Humans; Male; HIV InfectionsHIV InfectionsContinuum of care; Europe; HIV infection; Key population; Sexmedicine.disease_causekey population0302 clinical medicineContinuum of careHIV Infection030212 general & internal medicineMen having sex with menContinuum of caremedia_commoneducation.field_of_study[SDV.MHEP] Life Sciences [q-bio]/Human health and pathologyTransmission (medicine)Continuity of Patient CareEuropeInfectious DiseasesAcademicSubjects/MED00290Anti-Retroviral AgentsHIV infection continuum of care sex key population EuropeSexMicrobiology (medical)PopulationSocio-culturale03 medical and health sciencesAcquired immunodeficiency syndrome (AIDS)SDG 3 - Good Health and Well-beingmedicinemedia_common.cataloged_instanceHumansEuropean UnionEuropean unioneducationPandemicsHIV infection ; continuum of care ; sex ; key population ; Europebusiness.industrySARS-CoV-2COVID-19HIVmedicine.diseaseHIV infectioncontinuum of care030112 virologyMajor Articles and CommentariesKey populationAnti-Retroviral Agentbusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyDemography
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First Results on the Scalar WIMP-Pion Coupling, Using the XENON1T Experiment

2018

We present first results on the scalar coupling of weakly interacting massive particles (WIMPs) to pions from 1 t yr of exposure with the XENON1T experiment. This interaction is generated when the WIMP couples to a virtual pion exchanged between the nucleons in a nucleus. In contrast to most nonrelativistic operators, these pion-exchange currents can be coherently enhanced by the total number of nucleons and therefore may dominate in scenarios where spin-independent WIMP-nucleon interactions are suppressed. Moreover, for natural values of the couplings, they dominate over the spin-dependent channel due to their coherence in the nucleus. Using the signal model of this new WIMP-pion channel, …

Nuclear TheoryPhysics::Instrumentation and DetectorsNuclear TheoryGeneral Physics and Astronomy01 natural sciencesHigh Energy Physics - ExperimentHigh Energy Physics - Experiment (hep-ex)High Energy Physics - Phenomenology (hep-ph)WIMPPions[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Nuclear ExperimentS030UDMPhysicsStarke Wechselwirkung und exotische Kerne – Abteilung BlaumAstrophysics::Instrumentation and Methods for AstrophysicsnucleonsuppressionHigh Energy Physics - PhenomenologyWeakly interacting massive particlesmedicine.anatomical_structureWeakly interacting massive particlesNucleonCoherence (physics)Astrophysics - Cosmology and Nongalactic AstrophysicsWIMP nucleon: interactionParticle physicsCosmology and Nongalactic Astrophysics (astro-ph.CO)[PHYS.NUCL]Physics [physics]/Nuclear Theory [nucl-th]FOS: Physical sciencesWIMP: massspin: dependenceGravitation and Astrophysicsoperator: nonrelativisticDark matter Particle dark matter Pions Weakly interacting massive particles Dark matter detectorsNuclear Theory (nucl-th)PionParticle dark matter0103 physical sciencesmedicineDark mattercross section: upper limit010306 general physicsCouplingDark matter detectorsnucleusScalar (physics)coherenceDark Matter WIMP-Pion coupling Xenon Direct seartch[PHYS.HPHE]Physics [physics]/High Energy Physics - Phenomenology [hep-ph]High Energy Physics::Experiment[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]Nucleus
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Search for WIMP Inelastic Scattering off Xenon Nuclei with XENON100

2017

We present the first constraints on the spin-dependent, inelastic scattering cross section of weakly interacting massive particles (WIMPs) on nucleons from XENON100 data with an exposure of 7.64 ×103 kg .days . XENON100 is a dual-phase xenon time projection chamber with 62 kg of active mass, operated at the Laboratori Nazionali del Gran Sasso (LNGS) in Italy and designed to search for nuclear recoils from WIMP-nucleus interactions. Here we explore inelastic scattering, where a transition to a low-lying excited nuclear state of Xe 129 is induced. The experimental signature is a nuclear recoil observed together with the prompt deexcitation photon. We see no evidence for such inelastic WIMP-Xe…

Physics - Instrumentation and DetectorsXenonPhysics and Astronomy (miscellaneous)Physics::Instrumentation and Detectors[ PHYS.ASTR ] Physics [physics]/Astrophysics [astro-ph]01 natural sciencesHigh Energy Physics - ExperimentHigh Energy Physics - Experiment (hep-ex)XenonRecoilWIMP[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Dark MatterNuclear Experiment[ PHYS.PHYS.PHYS-INS-DET ] Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det]nucleus: recoilPhysicsTime projection chamberAstrophysics::Instrumentation and Methods for AstrophysicsWIMP nucleon: cross sectionInstrumentation and Detectors (physics.ins-det)Excited stateWeakly interacting massive particlesTPCNucleonchannel cross section: measuredsignatureAstrophysics - Cosmology and Nongalactic AstrophysicsParticle physicsdata analysis methodCosmology and Nongalactic Astrophysics (astro-ph.CO)WIMPchemistry.chemical_elementFOS: Physical sciencesInelastic scatteringspin: dependenceNuclear physicsstatistical analysis[ PHYS.HEXP ] Physics [physics]/High Energy Physics - Experiment [hep-ex]photon: emission0103 physical sciencescross section: inelastic scattering[PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det]010306 general physicsWIMP nucleon: inelastic scattering010308 nuclear & particles physicsS030DP2WIMP nucleus: interactionGran SassochemistryDirect Searchtime projection chamber: xenonHigh Energy Physics::Experiment[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]experimental results
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The Association of Intraoperative driving pressure with postoperative pulmonary complications in open versus closed abdominal surgery patients – a po…

2021

Abstract Background It is uncertain whether the association of the intraoperative driving pressure (ΔP) with postoperative pulmonary complications (PPCs) depends on the surgical approach during abdominal surgery. Our primary objective was to determine and compare the association of time–weighted average ΔP (ΔPTW) with PPCs. We also tested the association of ΔPTW with intraoperative adverse events. Methods Posthoc retrospective propensity score–weighted cohort analysis of patients undergoing open or closed abdominal surgery in the ‘Local ASsessment of Ventilatory management during General Anaesthesia for Surgery’ (LAS VEGAS) study, that included patients in 146 hospitals across 29 countries.…

Driving pressure; Laparoscopic surgery; Laparoscopy; PEEP; Perioperative ventilation; Pneumoperitoneum; Protective ventilation; Respiratory mechanics;Lung DiseasesMaleLaparoscopic surgery[SDV]Life Sciences [q-bio]medicine.medical_treatmentLaparoscopic surgeryCohort StudiesPositive-Pressure RespirationPostoperative Complications0302 clinical medicinePneumoperitoneum030202 anesthesiologyPneumoperitoneumAbdomenClinical endpointPerioperative ventilationMiddle Aged3. Good healthDriving pressure Laparoscopic surgery Laparoscopy PEEP Perioperative ventilation Pneumoperitoneum Protective ventilation Respiratory mechanicsDriving pressureFemaleResearch ArticleCohort studyProtective ventilationAdultmedicine.medical_specialtyAnestesi och intensivvårdRespiratory mechanicsAnesthesia GeneralNOlcsh:RD78.3-87.303 medical and health sciencesmedicineHumansPropensity ScoreAdverse effectPEEPAgedRetrospective StudiesDriving pressure; Laparoscopic surgery; Laparoscopy; PEEP; Perioperative ventilation; Pneumoperitoneum; Protective ventilation; Respiratory mechanicsAnesthesiology and Intensive Carebusiness.industryKirurgi030208 emergency & critical care medicineOdds ratiomedicine.diseaseRespiration ArtificialSurgeryAnesthesiology and Pain Medicinelcsh:AnesthesiologyRelative riskSurgeryLaparoscopyDriving pressure ; Laparoscopic surgery ; Laparoscopy ; PEEP ; Perioperative ventilation ; Pneumoperitoneum ; Protective ventilation ; Respiratory mechanics.businessAbdominal surgery
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Dark Matter Search Results from a One Ton-Year Exposure of XENON1T

2018

We report on a search for Weakly Interacting Massive Particles (WIMPs) using 278.8 days of data collected with the XENON1T experiment at LNGS. XENON1T utilizes a liquid xenon time projection chamber with a fiducial mass of $(1.30 \pm 0.01)$ t, resulting in a 1.0 t$\times$yr exposure. The energy region of interest, [1.4, 10.6] $\mathrm{keV_{ee}}$ ([4.9, 40.9] $\mathrm{keV_{nr}}$), exhibits an ultra-low electron recoil background rate of $(82\substack{+5 \\ -3}\textrm{ (sys)}\pm3\textrm{ (stat)})$ events/$(\mathrm{t}\times\mathrm{yr}\times\mathrm{keV_{ee}})$. No significant excess over background is found and a profile likelihood analysis parameterized in spatial and energy dimensions exclude…

Dark matterGeneral Physics and Astronomychemistry.chemical_elementS030DI5WIMP: massElectronParameter spacedark matter: direct detectionGravitation and AstrophysicsS030DI101 natural sciencesS030DI3S030DI2Nuclear physicsXenonRecoilWIMPelectron: recoil0103 physical sciencesS046DM2[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex][PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det]010306 general physicsnumerical calculationsDark Matter WIMP TPC XENON Direct searchPhysicsxenon: liquidTime projection chamber010308 nuclear & particles physicsbackgrounddark matter: massGran SassoWIMP nucleonchemistryWeakly interacting massive particles[PHYS.HPHE]Physics [physics]/High Energy Physics - Phenomenology [hep-ph]time projection chamber: xenon[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]
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Effect of Lung Recruitment and Titrated Positive End-Expiratory Pressure (PEEP) vs Low PEEP on Mortality in Patients With Acute Respiratory Distress …

2017

Importance The effects of recruitment maneuvers and positive end-expiratory pressure (PEEP) titration on clinical outcomes in patients with acute respiratory distress syndrome (ARDS) remain uncertain. Objective To determine if lung recruitment associated with PEEP titration according to the best respiratory-system compliance decreases 28-day mortality of patients with moderate to severe ARDS compared with a conventional low-PEEP strategy. Design, Setting, and Participants Multicenter, randomized trial conducted at 120 intensive care units (ICUs) from 9 countries from November 17, 2011, through April 25, 2017, enrolling adults with moderate to severe ARDS. Interventions An experimental strat…

AdultMaleARDSmedicine.medical_specialtyacure respitatory distress syndromemedicine.medical_treatmentmechanical ventilationlaw.inventionPositive-Pressure Respiration03 medical and health sciences0302 clinical medicineRandomized controlled triallawIntensive careTidal VolumemedicineHumansTreatment FailureARDS ventilation PEEPMED/41 - ANESTESIOLOGIAPEEPTidal volumePositive end-expiratory pressureAgedintensive careMechanical ventilationRespiratory Distress Syndromebusiness.industryHazard ratioPneumothorax030208 emergency & critical care medicineGeneral MedicineMiddle Agedmedicine.diseaseSurgeryIntensive Care UnitsEditorial030228 respiratory systemPneumothoraxAnesthesiaFemaleARDSbusiness
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First Dark Matter Search Results from the XENON1T Experiment

2017

We report the first dark matter search results from XENON1T, a ∼2000-kg-target-mass dual-phase (liquid-gas) xenon time projection chamber in operation at the Laboratori Nazionali del Gran Sasso in Italy and the first ton-scale detector of this kind. The blinded search used 34.2 live days of data acquired between November 2016 and January 2017. Inside the (1042±12)-kg fiducial mass and in the [5,40] keVnr energy range of interest for weakly interacting massive particle (WIMP) dark matter searches, the electronic recoil background was (1.93±0.25)×10-4 events/(kg×day×keVee), the lowest ever achieved in such a dark matter detector. A profile likelihood analysis shows that the data are consisten…

Xenon[ PHYS.ASTR ] Physics [physics]/Astrophysics [astro-ph]Massive particleGeneral Physics and Astronomy01 natural sciencesWIMP: dark matterHigh Energy Physics - ExperimentHigh Energy Physics - Experiment (hep-ex)High Energy Physics - Phenomenology (hep-ph)RecoilXenonWIMPS046DM2[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Dark Matter[ PHYS.PHYS.PHYS-INS-DET ] Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det]PhysicsRange (particle radiation)Time projection chamberDetectorHigh Energy Physics - Phenomenologydark matter: scatteringTPCAstrophysics - Instrumentation and Methods for AstrophysicsAstrophysics - Cosmology and Nongalactic AstrophysicsWIMP nucleon: interactionParticle physicsCosmology and Nongalactic Astrophysics (astro-ph.CO)WIMPDark matterFOS: Physical scienceschemistry.chemical_elementWIMP: massS030DI2Nuclear physicsPhysics and Astronomy (all)[ PHYS.HEXP ] Physics [physics]/High Energy Physics - Experiment [hep-ex]0103 physical sciencesrecoil[PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det]010306 general physicsInstrumentation and Methods for Astrophysics (astro-ph.IM)Physique010308 nuclear & particles physicsbackgrounddark matter: detectorAstronomieGran SassochemistryDirect Searchtime projection chamber: xenoninterpretation of experiments: XENON[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]
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