0000000000149715

AUTHOR

Umberto Bracale

showing 37 related works from this author

Retroaortic left renal vein and inflammatory abdominal aortic aneurysm

2010

The aim of this study was to report successful surgical management of an inflammatory abdominal aortic aneurysm associated with a retroaortic left renal vein. The patient, a 78-year-old man, presented with diffuse abdominal pain, fever, and constipation. Contrast-enhanced computed tomography showed soft tissue surrounding the aneurysm and a left renal vein behind the aorta. Intraoperative findings confirmed the CT images. The patient is alive and well 6 months postoperatively.

Pulmonary and Respiratory MedicineMalemedicine.medical_specialtyAbdominal painFeverAortographySettore MED/22 - Chirurgia VascolareRenal VeinsAortic aneurysmBlood Vessel Prosthesis ImplantationAneurysmmedicine.arteryMedicineHumansAgedInflammationAortabusiness.industrySoft tissueGeneral Medicinemedicine.diseaseCardiac surgeryAbdominal PainTreatment OutcomeCardiothoracic surgerycardiovascular systemInflammatory abdominal aortic aneurysm Retroaortic left renal vein Open repairSurgeryRadiologymedicine.symptomCardiology and Cardiovascular MedicinebusinessTomography X-Ray ComputedConstipationAbdominal surgeryAortic Aneurysm Abdominal
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Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

2023

Background: Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods: This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, r…

general surgeryacute care surgerySettore MED/18 - CHIRURGIA GENERALEclimate change; trauma; general surgery; acute care surgerySettore MED/40 - Ginecologia E Ostetriciaenvironmental impactsurgerySettore MED/31 - Otorinolaringoiatriaclimate changetraumaNoneMedicine and Health SciencesSurgeryoperating theatreenvironment
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Renewed endovascular repair for recurrent acute abdominal aortic aneurysm

2008

The aim of the study was to describe the successful endovascular management of a patient who was admitted urgently with a second episode of acute abdominal aortic aneurysm (AAA) 30 months after emergency endovascular abdominal aortic aneurysm repair (eEVAR) for a ruptured AAA. The patient, an 84 year-old male physician, presented with severe acute abdominal and back pain. Contrast-enhanced computer tomography scanning showed type III endoleak owing to complete disconnection of both graft limbs and the prosthetic main body. Treatment consisted of acute stent-grafting with two bridging stent-grafts to seal the endoleak and reline the graft. The patient is alive and well 6 months postoperative…

Malemedicine.medical_specialtyEndoleak type IIIRecurrent acuteSettore MED/22 - Chirurgia VascolareBlood Vessel Prosthesis ImplantationPostoperative ComplicationsRecurrenceEndovascular repairBack painmedicineHumansRadiology Nuclear Medicine and imagingcardiovascular diseasesAcute abdominal aortic aneurysmAged 80 and overEndoleak type IIbusiness.industrymedicine.diseaseAbdominal aortic aneurysmSurgerysurgical procedures operativeTreatment Outcomecardiovascular systemEmergency MedicineRadiologymedicine.symptombusinessTomography X-Ray ComputedAortic Aneurysm Abdominal
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Elective surgery system strengthening: development, measurement, and validation of the surgical preparedness index across 1632 hospitals in 119 count…

2022

© 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licenseBackground: The 2015 Lancet Commission on global surgery identified surgery and anaesthesia as indispensable parts of holistic health-care systems. However, COVID-19 exposed the fragility of planned surgical services around the world, which have also been neglected in pandemic recovery planning. This study aimed to develop and validate a novel index to support local elective surgical system strengthening and address growing backlogs. Methods: First, we performed an international consultation through a four-stage consensus process to develop a multidomain index for hospital-level assess…

MaleHealth system resilience.*COVID-19/epidemiologySocial SciencesSağlık BilimleriGlobal HealthFundamental Medical SciencesClinical Medicine (MED)AnaesthesiasurgeryTIP GENEL & DAHİLİnisu navedene ključne riječiElective backlogMedicine and Health SciencesTOOLKlinik Tıp (MED)610 Medicine & healthMEDICINE GENERAL & INTERNAL11 Medical and Health SciencesKlinik Tıpsurgery; global surgery; health-care systemCovid19NIHR Global Health Unit on Global SurgeryGeneral MedicineHospitalsHospital preparedneTıphealth-care systemElective Surgical ProceduresHEALTH SYSTEMS*PandemicsMedicineFemaleLife Sciences & BiomedicineHumanHälso- och sjukvårdsorganisation hälsopolitik och hälsoekonomiTemel Tıp Bilimleri610 Medicine & healthglobal surgeryGenel TıpCAPACITYCOVIDSurg CollaborativeHospitalMedicine General & InternalGeneral & Internal MedicineHealth SciencesHumansPandemicsScience & TechnologyElective Surgical ProcedurePandemicKirurgiPlanned surgeryCOVID-19Health Care Service and Management Health Policy and Services and Health EconomyCLINICAL MEDICINESettore MED/18Settore MED/18 - Chirurgia Generaleelective surgeryHospital assessmentSystems strengtheningSurgeryHuman medicineMETHODOLOGY[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
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How should I treat concomitant post-endarterectomy carotid pseudoaneurysm and contralateral symptomatic stenosis?

2010

Background A 74-year-old male patient complaining of crescendo TIAs, hypertension and hyperlipidaemia. Investigation Duplex ultrasound scan MR angiography. Diagnosis Pseudoaneurysm stemming from the ICA. Treatment An open or endovascular procedure for the right pECCA repair, or a left CEA or CAS.

Malemedicine.medical_specialtymedicine.medical_treatmentEndarterectomycarotid artery stenosistent graftSettore MED/22 - Chirurgia VascolareCentral nervous system diseasePseudoaneurysmmedicineHumansCarotid Stenosiscardiovascular diseasesCarotid PseudoaneurysmEndarterectomyAgedVascular diseasebusiness.industrymedicine.diseasecarotid pseudoaneurysmSurgeryStenosisMale patientConcomitantcardiovascular systemstentRadiologyCardiology and Cardiovascular MedicinebusinessCarotid Artery InjuriesCarotid Artery InternalEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
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Gluteal Compartment Syndrome Following Abdominal Aortic Aneurysm Treatment: Case Report and Review of the Literature

2016

Compartment syndrome (CS) is a pathological increase of the interstitial pressure within the closed osseous fascial compartments. Trauma is the most common cause, followed by embolization, burns, and iatrogenic injuries; it usually involves the limbs. The major issue when dealing with CS is the possibility to do an early diagnosis in order to intervene precociously, through a fasciotomy, reducing the risk of tissue, vascular and nervous damage. Although it is an infrequent condition, it is potentially life threatening. In our case report, we present a 59-year-old patient, smoker, affected by hypertension, dyslipidemia, chronic renal failure, and morbid obesity who came at our attention for …

medicine.medical_specialtymedicine.medical_treatment030204 cardiovascular system & hematologyCompartment SyndromesFasciotomyopen surgery03 medical and health sciences0302 clinical medicineabdominal aortic aneurysmmedicine.arterymedicineHumans030212 general & internal medicineEmbolizationbusiness.industryStentGeneral MedicineAortic bifurcationMiddle Agedmedicine.diseaseThrombosisCommon iliac arteryAbdominal aortic aneurysmFasciotomySurgerybody regionsdermo-fasciotomymedicine.anatomical_structureblended anesthesiaAnesthesiaButtocksSurgeryHemodialysisbusinessgluteal compartment syndromeVascular Surgical ProceduresAortic Aneurysm Abdominal
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Symptomatic Deep Femoral Artery Pseudoaneurysm Endovascular Exclusion. Case Report and Literature Review.

2017

Deep femoral artery pseudoaneurysms (DFAPs) are rare and generally occur after penetrating trauma or surgical procedures. A 36-year-old obese man presented with pain in correspondence of the anterior-lateral thigh after 6 months from gunshot wound. Duplex and computed tomography (CT) showed a bilobed right DFAP (maximal diameter 12.9 cm). The patient was managed urgently, under local anesthesia, by placement in the distal DFA of a Viabahn 8 × 100-mm stent graft (W L Gore & Associates, Inc). The postoperative course was uneventful, and the 24-month CT showed regular stent-graft patency and 20-mm DFAP shrinkage. The literature review reported 8 cases of DFAPs; of these 6 were managed by endo…

AdultMalemedicine.medical_specialtyComputed Tomography Angiographymedicine.medical_treatment030204 cardiovascular system & hematologySettore MED/22 - Chirurgia Vascolare030218 nuclear medicine & medical imaging03 medical and health sciencesPseudoaneurysmBlood Vessel Prosthesis Implantation0302 clinical medicineAneurysmBlood vessel prosthesisDeep Femoral ArteryMedicineVascular PatencyHumansVascular PatencyUltrasonography Doppler Duplexbusiness.industryEndovascular ProceduresStentGeneral Medicinemedicine.diseaseSurgeryBlood Vessel ProsthesisFemoral Arterysurgical procedures operativeTreatment OutcomeRegional Blood FlowSurgeryStentsWounds GunshotRadiologyGunshot woundbusinessCardiology and Cardiovascular MedicinePenetrating traumaAneurysm FalseAnnals of vascular surgery
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Basal Cerebral Computed Tomography as Diagnostic Tool to Improve Patient Selection in Asymptomatic Carotid Artery Stenosis

2012

One-hundred patients were included to evaluate the role of cerebral computed tomography (CT) to improve patient selection in asymptomatic internal carotid stenosis. Symptomatic patients were assigned to group A, asymptomatic patients to group B. A cerebral CT pattern A was observed in groups A and B in 60% and 20%, respectively ( P < .0001). Between A and B groups, type 6 plaques were found, respectively, in 26.7% and 7.5% of patients ( P = .01); a type 5 in 51.7% and 45% ( P = .32) of patients; and a type 4 in 21.7% and 47.5% of patients, respectively ( P = .006). Within B group, the association of CT pattern A and histological plaque level 4, 5, and 6 was, respectively, 25% ( P = .15)…

Malemedicine.medical_specialtyeducationComputed tomographyComorbiditySettore MED/22 - Chirurgia VascolareAsymptomaticBrain IschemiaBasal (phylogenetics)Predictive Value of TestsRisk FactorsmedicineHumansCarotid StenosisIn patientProspective StudiesAsymptomatic carotid artery stenosisAgedNeurologic Examinationmedicine.diagnostic_testbusiness.industryPatient SelectionMiddle Agedmedicine.diseasecarotid surgery asymptomatic artery stenosis computed tomographyStenosisTreatment Outcomemedicine.anatomical_structureFemaleRadiologymedicine.symptomTomography X-Ray ComputedCardiology and Cardiovascular MedicinebusinessCarotid Artery InternalArteryAngiology
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Case report of a large cephalic vein aneurysm inducing heart failure in a renal transplant patient with radio-cephalic fistula for haemodialysis

2020

Highlights • The venous aneurysm is one of the most common complications of autologous AVF. • The vein aneurysm should be treat by surgical resection and anastomotic ligature. • AVF shouldn’t be ligated from 1-year kidney transplantation except in some cases. • Surgical ligation to prevent complications could be considered an option.

medicine.medical_specialtycongenital hereditary and neonatal diseases and abnormalitiesFistulaArteriovenous fistulaCase ReportHeart failure03 medical and health sciences0302 clinical medicineAneurysmmedicinecardiovascular diseasesVeinKidney transplantationArteriovenous fistulaCephalic veinbusiness.industryRenal transplantationmedicine.diseaseSurgeryTransplantationmedicine.anatomical_structure030220 oncology & carcinogenesiscardiovascular system030211 gastroenterology & hepatologySurgerybusinessKidney diseaseSurgical repairInternational Journal of Surgery Case Reports
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Endograft connector technique to treat popliteal artery aneurysm in a morbid obese patient.

2015

Surgical repair of popliteal artery aneurysm in morbid obese patients poses additional challenges. We report a morbid obese patient who had a 59 mm right popliteal artery aneurysm which was successfully treated with the endograft connector technique. This technique was used to perform the distal anastomosis of the below-knee femoro-popliteal bypass. A 10 mm Dacron graft was used as a main graft bypass and an 11 mm/10 cm stentgraft as endograft connector. Following the respective tunnel of the Dacron graft, an end-to-side proximal anastomosis was performed at distal femoral artery. The aneurysm exclusion was obtained through a proximal and a distal ligation. Postoperative duplex showed adeq…

Malemedicine.medical_specialtyPopliteal artery aneurysmmedicine.medical_treatmentFemoral arterySettore MED/22 - Chirurgia VascolareBlood Vessel Prosthesis ImplantationAneurysmfemoro-popliteal bypamedicine.arterymedicineHumansRadiology Nuclear Medicine and imagingPopliteal ArteryVascular PatencySurgical repairPopliteal artery aneurysm femoro-popliteal bypass sutureless anastomosisbusiness.industryAnastomosis SurgicalPopliteal artery aneurysmStentGeneral MedicineRight popliteal arteryMiddle Agedmedicine.diseaseAneurysmSurgerysutureless anastomosisFemoral ArteryStenosisTreatment OutcomeSurgeryStentsRadiologyCardiology and Cardiovascular MedicinebusinessLigationVascular
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Total occlusion of aortic arch in a 62-year-old man presenting with acute myocardial infarction

2011

Not available

Aortic archMalemedicine.medical_specialtyTiclopidineAortic DiseasesMyocardial Infarctionacute myocardial infarctionAorta ThoracicCoronary AngiographyTotal occlusionSettore MED/22 - Chirurgia Vascolaremedicine.arteryInternal medicinemedicineHumansaortic arch occlusionMyocardial infarctionAngioplasty Balloon CoronaryEnoxaparinbusiness.industryGeneral MedicineMiddle Agedmedicine.diseaseClopidogrelaortic arch occlusion myocardial infarction endovascular repair stent-graftCardiologyStentsCardiology and Cardiovascular MedicinebusinessTomography X-Ray Computedcomputed tomography angiography
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Position Paper on Young Vascular Surgeons Training of the Mediterranean Federation for the Advancing of Vascular Surgery (MeFAVS): State of the Art a…

2021

ABSTRACT The Mediterranean Federation for the Advancing of Vascular Surgery (MeFAVS) was founded in 2018, with the aim to promote cooperation among vascular professionals within Mediterranean countries. Due to its prominent social and economic impact on national health systems, diabetic peripheral artery was selected as the very first topic to be investigated by the federation. In this second paper, different experiences from delegates of participating countries were shared to define common strategies to harmonize, standardize, and optimize education and training in the Vascular Surgery specialty.

medicine.medical_specialtyArterial diseasemedia_common.quotation_subjectVascular SurgerySettore MED/22 - Chirurgia VascolareTraining (civil)Peripheral Arterial DiseaseState (polity)medicineMediterranean SeaHumansTrainingEconomic impact analysisVascular surgery specialtymedia_commonNational healthSurgeonsbusiness.industryMediterranean RegionInternship and ResidencyGeneral MedicineVascular surgeryendovascular surgery; Mediterranean sea; training; vascular surgeryEducation Medical GraduateFamily medicineEndovascular SurgeryPosition paperSurgeryClinical CompetenceCurriculumCardiology and Cardiovascular MedicinebusinessVascular Surgical ProceduresDiabetic AngiopathiesLearning CurveProgram EvaluationSpecialization
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Stent-assisted detachable coil embolization of wide-necked renal artery aneurysms

2017

Renal artery aneurysms (RAAs) are rare with an estimated incidence of 0.1% in the general population, and they represent approximately 25% of all visceral aneurysms. The gold standard of treatment is open surgery, but it is associated with a high risk of nephrectomy, mortality, and morbidity. Less invasive endovascular therapies are becoming increasingly common for the treatment of RAAs. Here, we aimed to report three cases of wide-necked complex renal artery aneurysms treated endovascularly using stent-assisted coil embolization with self-expandable stent nitinol Solitaire AB and Concerto Axium coils. In addition, we describe the use of the waffle-cone technique in a case of wide-necked sa…

AdultMalemedicine.medical_specialtymedicine.medical_treatmentPopulationSelf Expandable Metallic StentsAdult; Aged; Aneurysm; Blood Vessel Prosthesis; Embolization Therapeutic; Humans; Male; Middle Aged; Renal Artery; Self Expandable Metallic Stents; Treatment Outcome; Radiology Nuclear Medicine and Imaging; Cardiology and Cardiovascular Medicine030204 cardiovascular system & hematologySettore MED/22 - Chirurgia Vascolare030218 nuclear medicine & medical imaging03 medical and health sciencesRenal Artery0302 clinical medicineAneurysmSelf-expandable metallic stentBlood vessel prosthesismedicine.arteryInterventional RadiologymedicineHumansRadiology Nuclear Medicine and imagingcardiovascular diseasesEmbolizationRenal arteryeducationSelf Expandable Metallic StentAgededucation.field_of_studybusiness.industryStentMiddle Agedmedicine.diseaseAneurysmEmbolization TherapeuticNephrectomyBlood Vessel ProsthesisBlood Vessel ProsthesiTreatment Outcomecardiovascular systemRadiologyCardiology and Cardiovascular MedicinebusinessHumanDiagnostic and Interventional Radiology
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Endovascular Management of a Giant Celiac Artery Aneurysm

2012

Malemedicine.medical_specialtybusiness.industryEndovascular ProceduresContrast MediaVascular plugGeneral MedicineMiddle AgedAneurysmEmbolization TherapeuticCeliac artery aneurysmImaging Three-DimensionalText miningCeliac ArteryInternal MedicinemedicineHumansRadiologyTomography X-Ray ComputedbusinessCoil embolizationInternal Medicine
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Anastomotic Pseudoaneurysm Complicating Renal Transplantation: Treatment Options

2010

Introduction: Anastomotic pseudoaneurysm following renal transplantation is uncommon. Indications for repair, treatment options and outcomes remain controversial. Report: We present 6 renal transplant recipients with large anastomotic pseudoaneurysms. Five of the patients underwent open repair while one had a stent-grafting and delayed transplant nephrectomy for a ruptured pseudoaneurysm. A transplant nephrectomy was needed in all cases but one. Arterial reconstruction enabled limb salvage in all cases. One patient died of sepsis postoperatively. No patient presented late infection, failure of vascular reconstruction, nor pseudoaneurysm recurrence. Conclusions: Surgical excision of anastomo…

MaleTime FactorsSettore MED/22 - Chirurgia VascolareNephrectomyTransplant nephrectomyPseudoaneurysmRenal ArteryStentTransplantation HomologouMedicine(all)Open repairAnastomosis SurgicalTreatment optionsMiddle AgedBlood Vessel ProsthesiTreatment Outcomesurgical procedures operativecardiovascular systemOpen repairFemaleStentsRadiologyCardiology and Cardiovascular MedicineAneurysm FalseHumanAdultReoperationmedicine.medical_specialtyTime FactorAnastomosisIliac ArterySepsisBlood Vessel Prosthesis ImplantationAneurysmEndovascular repairmedicineHumansTransplantation HomologousStent-graftcardiovascular diseasesAgedbusiness.industryRenal transplantationmedicine.diseaseKidney TransplantationSurgeryBlood Vessel ProsthesisTransplantationSurgerybusinessTomography X-Ray ComputedAneurysm InfectedEuropean Journal of Vascular and Endovascular Surgery
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Hybrid Endograft Solution for Complex Iliac Anatomy

2010

The purpose of this study was to evaluate single-center results with selective use of Gore Excluder limbs (W.L. Gore & Associates, Flagstaff, AZ) in a Cook Zenith body (Cook Inc, Bloomington, IN) for elective endovascular abdominal aortic aneurysm (AAA) repair. A prospectively held database for patients with AAA, who were treated endovascularly between March 1999 and July 2008, was queried for patients treated with a Cook Zenith body and one or two Gore Excluder limbs. Indication, technical success, late limb occlusion, and disconnection were evaluated. From 276 patients who were treated with a Zenith body, 29 underwent repair with hybrid graft components with, in total, 41 Gore Exclud…

MaleTime FactorsOCCLUSIONmedicine.medical_treatmentSettore MED/22 - Chirurgia VascolareEndovascular aneurysm repairendovascular aneurysm repairAortic aneurysmOcclusionEVARAged 80 and overOUTCOMESmedicine.diagnostic_testGeneral MedicineAnatomyAbdominal aortic aneurysmTreatment OutcomeElective Surgical ProceduresFemaleRadiologyCardiology and Cardiovascular MedicineElective Surgical Proceduremedicine.medical_specialtyAortographyProsthesis DesignAortographyIliac ArteryBlood Vessel Prosthesis Implantationabdominal aortic aneurysm endovascular aneurysm repair Excluder limbs hybrid graft iliac tortuosityabdominal aortic aneurysmBlood vessel prosthesismedicineHumansExcluder limbsRadiology Nuclear Medicine and imagingAgedRetrospective Studiesbusiness.industryENDOVASCULAR REPAIRAORTIC-ANEURYSM REPAIRmedicine.diseaseSurgeryBlood Vessel Prosthesisiliac tortuosityFeasibility StudiesSurgeryhybrid graftSTENT-GRAFTSbusinessTomography X-Ray ComputedAbdominal surgeryAortic Aneurysm AbdominalVascular
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The SIC-GIRCG 2013 Consensus Conference on Gastric Cancer.

2014

Abstract The topic chosen by the Board of the Italian Society of Surgery for the 2013 annual Consensus Conference was gastric cancer. With this purpose, under the direction of 2 chairmen, 36 experts nominated by the Regional Societies of Surgery and by the Italian Research Group for Gastric Cancer (GIRCG) participated in an experts consensus exercise, preceded by a questionnaire and mainly held by telematic vote, in accordance with the rules of the Delphi method. The results of this Consensus Conference, presented to the 115th National Congress of the Italian Society of Surgery, and approved in plenary session, are reported in the present paper.

Malemedicine.medical_specialtyGastric cancer Surgery Chemotherapy Staging Endoscopy LaparoscopyStagingDelphi TechniqueMEDLINEDelphi methodchemotherapyEndosonographyDelphi Technique; Endosonography; Female; Humans; Italy; Lymph Node Excision; Male; Neoplasm Staging; Societies Medical; Stomach NeoplasmsStomach NeoplasmStomach NeoplasmsMedicalmedicineHumanslapaoscopyguidelinesgastric cancer; chemotherapy; staging endoscopy; lapaoscopySocieties MedicalNeoplasm StagingSettore MED/06 - ONCOLOGIA MEDICAtreatmentbusiness.industryConsensus conferenceCancerEndoscopymedicine.diseasePlenary sessionSurgerySettore MED/18 - Chirurgia GeneraleGastric CancerItalyLymph Node ExcisionNeoplasm stagingLaparoscopySurgeryFemaleguidelines; Gastric Cancer; treatmentbusinessSocietiesstaging endoscopyHuman
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Endograft repair of spontaneous infrarenal abdominal aortic dissection

2005

A 71-year-old man with a history of hypertension and a recent myocardial infarction experienced a sudden periumbilical and back pain. Abdominal tenderness was found at physical examination, with no changes in electrocardiogram and serial enzyme determinations. Computed tomographic angiography (CTA) showed a normal thoracic aorta, an infrarenal aortic dissection extending into the left common iliac artery and a contralateral iliac occlusive disease (A, Cover). Although antihypertensive therapy was administered, the patient had persistent pain; subsequently, he underwent endovascular repair with a bifurcated stent graft (Talent, Medtronic Ave, Santa Rosa, Calif) introduced via the left femora…

Malemedicine.medical_specialtymedicine.medical_treatmentDissection (medical)Settore MED/22 - Chirurgia VascolareAneurysm Dissectingmedicine.arteryMedicineThoracic aortaHumanscardiovascular diseasesAgedAortic dissectionbusiness.industryVascular diseaseAbdominal aortaStentendovascular repair aortic dissectionLeft Common Iliac Arterymedicine.diseaseAortic DissectionIntroducer sheathSurgeryRadiologybusinessCardiology and Cardiovascular MedicineVascular Surgical ProceduresHumanAortic Aneurysm AbdominalJournal of Vascular Surgery
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Late carotid artery stent erosion and pseudoaneurysm after accidental hyperextension of the neck

2010

A 75-year-old man was referred to our unit complaining of a large pulsatile neck mass that appeared 2 days after an accidental fall and hyperextension of the neck. One month earlier, he was submitted to left carotid artery stenting for symptomatic high-grade stenosis. His medical history included diabetes mellitus, coronary artery disease, and a right femoropopliteal bypass for critical limb ischemia. At the time of admission, he was afebrile and had no evidence of local erythema, draining sinus, or leukocytosis. Moreover, C-reactive protein was 1 mg/dL. The clinical examination revealed a large swelling in the region of the left carotid bifurcation and mild dyspnea. Arterial duplex imaging…

MaleCarotid Artery Diseasesmedicine.medical_specialtymedicine.medical_treatmentcarotid artery stenosistent graftNeck InjuriesPseudoaneurysmmedicine.arteryIntensive careHumansMedicineCarotid Stenosiscardiovascular diseasesCommon carotid arteryAccidental fallCarotid PseudoaneurysmAgedComputed tomography angiographymedicine.diagnostic_testbusiness.industryAngioplastypseudoaneurysmStentCritical limb ischemiamedicine.diseaseSurgeryTreatment Outcomecardiovascular systemStentsSurgerymedicine.symptomTomography X-Ray ComputedCardiology and Cardiovascular MedicinebusinessAneurysm FalseJournal of Vascular Surgery
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SARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study

2021

SARS-CoV-2 has been associated with an increased rate of venous thromboembolism in critically ill patients. Since surgical patients are already at higher risk of venous thromboembolism than general populations, this study aimed to determine if patients with peri-operative or prior SARS-CoV-2 were at further increased risk of venous thromboembolism. We conducted a planned sub-study and analysis from an international, multicentre, prospective cohort study of elective and emergency patients undergoing surgery during October 2020. Patients from all surgical specialties were included. The primary outcome measure was venous thromboembolism (pulmonary embolism or deep vein thrombosis) within 30 da…

Malepulmonary embolismInternationalitySettore MED/18 - CHIRURGIA GENERALEDeep veinVascular damage Radboud Institute for Health Sciences [Radboudumc 16]infectious diseasesCardiovascularSARS‐CoV‐2surgeryCOVID-19 ; SARS-CoV-2 ; deep vein thrombosis ; pulmonary embolism ; venous thromboembolismCohort StudiesPostoperative ComplicationsAnesthesiologyMedicine and Health SciencesProspective Studies610 Medicine & healthProspective cohort studyLung11 Medical and Health SciencesConfoundingHematologyMiddle AgedThrombosis17 Psychology and Cognitive SciencesCOVID-19; deep vein thrombosis; pulmonary embolism; SARS-CoV-2; venous thromboembolismPulmonary embolismCOVID-19; SARS-CoV-2; deep vein thrombosis; pulmonary embolism; venous thromboembolism.medicine.anatomical_structureCohortCOVID-19/complicationsPostoperative Complications/etiologyOriginal ArticleFemalePatient SafetyLife Sciences & BiomedicineCOVID-19; SARS-CoV-2; deep vein thrombosis; pulmonary embolism; venous thromboembolismHumanAdultmedicine.medical_specialtyAdolescentClinical Sciencesvenous thromboembolism610 Medicine & healthGlobalSurg CollaborativeVenous Thromboembolism/etiologydeep vein thrombosisNOCOVIDSurg CollaborativeYoung AdultMedicine General & InternalAge DistributionClinical ResearchCOVID‐19General & Internal MedicinemedicineHumansSex DistributionAgedScience & Technologybusiness.industrySARS-CoV-2PreventionNeurosciencesdeep vein thrombosiCOVID-19PneumoniaOdds ratioOriginal Articlesmedicine.diseaseSurgeryReconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10]Prospective StudieGood Health and Well BeingAnesthesiology and Pain MedicineHuman medicinePostoperative ComplicationCohort StudiebusinessVenous thromboembolism[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
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The Endovascular Management of an Iatrogenic Superior Gluteal Artery Rupture Following Bone Marrow Biopsy

2017

We herein report an uncommon case of a life-threatening retroperitoneal hematoma after a bone marrow biopsy. Two hours after iliac crest bone harvesting, the patient experienced syncope and severe hypotension. Urgent contrast-enhanced computed tomography demonstrated extravasation from the superior gluteal artery. Transcatheter coil embolization was performed successfully, without complications. Life-threatening complications caused by retroperitoneal bleeding after bone marrow biopsy are very rare. There are few reports on the use of endovascular treatment in the management of life-threatening hemorrhagic complications after bone marrow biopsy.

endovascular treatmentAdultmedicine.medical_specialtyAortic RuptureBiopsyIatrogenic DiseaseCase ReportHemorrhageiatrogenic complication030204 cardiovascular system & hematologyIliac crestIliac Artery03 medical and health sciences0302 clinical medicineBone MarrowSuperior gluteal arterymedicine.arteryBiopsyInternal MedicinemedicineHumansAorta AbdominalRetroperitoneal SpaceEndovascular treatmentCoil embolizationmedicine.diagnostic_testbusiness.industryEndovascular ProceduresGeneral MedicineEmbolization TherapeuticExtravasationSurgerymedicine.anatomical_structurebone marrow biopsyTreatment OutcomeHemorrhagic complicationsuperior gluteal arteryFemaleRadiologyBone marrowbusiness030215 immunologyInternal Medicine
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A wire-loop technique for implantation of an iliac branched device in a patient with previous surgery for a ruptured abdominal aortic aneurysm

2013

We described a modified technique for implanting a bridging stent-graft into an iliac branched device. A 79-year-old male who had received aortobiiliac synthetic graft surgery for a ruptured abdominal aortic aneurysm six months earlier was admitted to our unit for treatment of a left common iliac aneurysm involving the origin of the hypogastric artery. A standard technique was unsuccessful at implanting the bridging stent-graft, and therefore a wire-loop guidewire over the graft bifurcation was used to stabilize the contralateral sheaths and to complete the implantation. © Turkish Society of Radiology 2012.

Malemedicine.medical_specialtyRadiology Nuclear Medicine and ImagingBridging (networking)Common iliac aneurysmProsthesis DesignIliac ArterySettore MED/22 - Chirurgia VascolareWire-loop techniqueFollow-Up StudieBlood Vessel Prosthesis ImplantationmedicineStentHumanscardiovascular diseasesAgedEndovascular; Iliac aneurysm; Wire-loop technique; Aged; Aortic Aneurysm Abdominal; Blood Vessel Prosthesis Implantation; Follow-Up Studies; Humans; Iliac Aneurysm; Iliac Artery; Male; Prosthesis Design; Treatment Outcome; Blood Vessel Prosthesis; Stents; Radiology Nuclear Medicine and Imaging; Cardiology and Cardiovascular MedicineRuptured abdominal aortic aneurysmEndovascularbusiness.industrySynthetic graftStandard techniqueSurgeryBlood Vessel ProsthesisIliac aneurysmBlood Vessel Prosthesisurgical procedures operativemedicine.anatomical_structureTreatment OutcomeStentsRadiologybusinessCardiology and Cardiovascular MedicineWire loopArteryFollow-Up StudiesAortic Aneurysm AbdominalHuman
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Carotid artery stenting with contralateral carotid occlusion in a rare aortic arch configuration

2010

We present the case of a 47-year-old man admitted to our department with an episode of aphasia. Duplex scan showed an occluded right internal carotid artery and severe left internal carotid artery stenosis. Contrast-enhanced computer tomography demonstrated a common trunk for both common carotid arteries anterior to the trachea and aberrant right subclavian artery posterior to the esophagus. The patient was considered to be a high risk for carotid endarterectomy and, consequently, we performed stenting of the left carotid artery. To our knowledge, this is the first case reporting the combination of these two aortic arch anomalies and the concomitant endovascular treatment of atherosclerotic…

MaleAortic archmedicine.medical_specialtyVascular Malformationsmedicine.medical_treatmentCarotid arteriesCarotid StenosiSubclavian ArteryAorta ThoracicCarotid endarterectomySettore MED/22 - Chirurgia Vascolaremedicine.arteryInternal medicineStentcarotid artery disease aortic arch anomalies carotid stenting contralateral occlusionmedicinecarotid occlusionHumansThoracic aortaCarotid Stenosiscardiovascular diseasesEsophagusaortic arch anomalieSubclavian arteryUltrasonography Doppler DuplexVascular Malformationcarotid artery stentingbusiness.industryMedicine (all)General MedicineMiddle Agedmedicine.diseaseStenosisTreatment Outcomemedicine.anatomical_structureConcomitantcardiovascular systemCardiologyStentsTomography X-Ray ComputedCardiology and Cardiovascular MedicinebusinessAngioplasty BalloonCarotid Artery InternalHumanJournal of Cardiovascular Medicine
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Single staged hybrid approach for multilevel aortic-iliac-femoral-popliteal disease

2020

Highlights • Multilevel peripheral arterial disease in diabetic patients is cause of amputation. • Herein we report a case of critic limb ischemia addressed by hybrid procedure. • Hybrid procedure outcomes seem to be as good as with open revascularization. • Hybrid procedure show less morbidity and shorter intensive care and hospital stay.

medicine.medical_specialtyArterial diseasemedicine.medical_treatmentDiseaseRevascularizationRenal artery stenosisSettore MED/22 - Chirurgia Vascolare03 medical and health sciences0302 clinical medicineIntensive caremedicine.arteryCase reportPeripheral arterial diseasemedicineRenal arteryEndovascularRevascularization.business.industryRevascularizationBlood flowHybrid approachmedicine.diseaseSurgeryHybrid procedure030220 oncology & carcinogenesis030211 gastroenterology & hepatologySurgerybusinessInternational Journal of Surgery Case Reports
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Chest pain due to late huge coronary pseudoaneurysm following stent implantation

2011

A 50-year-old man was referred to our hospital because of persistent atypical chest pain. His past medical history was remarkable for a non ST elevation myocardial infarction, treated five months previously with PCI on the right coronary artery. Two months later, for chest pain, he underwent coronary angiography that showed a right coronary artery with slight ectasia near the stent. Five months later for the persistence of atypical chest pain he came to our clinic. Chest CT showed a 31.5 mm hematoma of the right coronary artery. Coronary angiography revealed a giant aneurysm, proximal to the stent. In the light of rapid growth of aneurysm, the risk of rupture and symptoms, we decided to tre…

Malemedicine.medical_specialtyChest PainTime Factorsmedicine.medical_treatmentChest painCoronary AngiographyHematomaAneurysmEctasiamedicine.arteryInternal MedicinemedicineStentHumanscardiovascular diseasesMyocardial infarctionCoronary Vesselbusiness.industryStentGeneral MedicineMiddle Agedmedicine.diseaseCoronary Vesselssurgical procedures operativeRight coronary arteryConventional PCIStentsRadiologymedicine.symptombusinessAneurysm FalseHuman
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Fenestrated Stent Grafting for Short-necked and Juxtarenal Abdominal Aortic Aneurysm

2010

Objectives: To present an 8-year clinical experience in the endovascular treatment of short-necked and juxtarenal abdominal aortic aneurysm (AAA) with fenestrated stent grafts. Methods: At our tertiary referral centre, all patients treated with fenestrated and branched stent grafts have been enrolled in an investigational device protocol database. Patients with short-necked or juxtarenal AAA managed with fenestrated endovascular aneurysm repair (F-EVAR) between November 2001 and April 2009 were retrospectively reviewed. Patients treated at other hospitals under the supervision of the main author were excluded from the study. Patients treated for suprarenal or thoraco-abdominal aneurysms wer…

MaleTime Factorsmedicine.medical_treatmentShort neckFenestrated graftKaplan-Meier EstimateOPEN REPAIREndovascular aneurysm repairSettore MED/22 - Chirurgia VascolareAortic aneurysmEVARNetherlandsAged 80 and overMedicine(all)medicine.diagnostic_testENDOGRAFT REPAIRMiddle AgedJuxtarenalAbdominal aortic aneurysmProsthesis FailureTreatment OutcomeFemaleKidney DiseasesStentsCardiology and Cardiovascular MedicineReoperationmedicine.medical_specialtyAortographyArterial Occlusive DiseasesFenestrated graftsProsthesis DesignAortographyRisk AssessmentBlood Vessel Prosthesis ImplantationAneurysmRenal DialysisBlood vessel prosthesismedicineHumanscardiovascular diseasesAgedRetrospective Studiesbusiness.industryStentENDOVASCULAR REPAIRmedicine.diseaseAneurysmBlood Vessel ProsthesisSurgeryAbdominal aortic aneurysmSurgerybusinessTomography Spiral ComputedAortic Aneurysm AbdominalAbdominal surgeryEuropean Journal of Vascular and Endovascular Surgery
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Late, giant brachial artery aneurysm following hemodialysis fistula ligation in a renal transplant patient: case report and literature review.

2012

Brachial artery aneurysm (BAA) following long-standing arteriovenous fistula ligation after renal transplantation is uncommon. Herein, we describe the case of a 64-year-old man who developed a giant symptomatic BAA 21 years after ligation of the fistula. He was submitted to surgical excision of the aneurysm followed by interposition prosthetic graft.

MalePulmonary and Respiratory Medicinemedicine.medical_specialtyBrachial ArteryFistulamedicine.medical_treatmentArteriovenous fistulaSettore MED/22 - Chirurgia VascolareArteriovenous Shunt SurgicalAneurysmRenal Dialysismedicine.arterymedicineHumanscardiovascular diseasesBrachial arteryLigationbusiness.industryBrachial artery aneurysm Renal transplantation Dialysis Surgical bypassGeneral MedicineMiddle Agedmedicine.diseaseAneurysmKidney TransplantationSurgeryTransplantationCardiothoracic surgerycardiovascular systemSurgeryRadiologyHemodialysisCardiology and Cardiovascular MedicineLigationbusiness
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Endovascular treatment of spontaneous isolated abdominal aortic dissection

2016

Isolated abdominal aortic dissection is a rare clinical disease representing only 1.3% of all dissections. There are a few case series reported in the literature. The causes of this pathology can be spontaneous, iatrogenic, or traumatic. Most patients are asymptomatic and symptoms are usually abdominal or back pain, while claudication and lower limb ischemia are rare. Surgical and endovascular treatment are two valid options with acceptable results. We herein describe nine cases of symptomatic spontaneous isolated abdominal aortic dissection, out of which four successfully were treated with an endovascular approach between July 2003 and July 2013. All patients were men, smokers, symptomati…

lcsh:Medical physics. Medical radiology. Nuclear medicinemedicine.medical_specialtymedicine.medical_treatmentlcsh:R895-920endovascular techniqueCase Report030204 cardiovascular system & hematologystent graftAsymptomaticSettore MED/22 - Chirurgia Vascolare03 medical and health sciences0302 clinical medicinemedicine.arterymedicineBack pain030212 general & internal medicinecardiovascular diseasesAbdominal aortaComputed tomography angiographyAortic dissectionmedicine.diagnostic_testbusiness.industryAbdominal aortastent graftsStentAbdominal aorta; dissection; endovascular technique; stent grafts; stentsGeneral Medicinemedicine.diseaseSurgeryDissectiondissectionstentsmedicine.symptomClaudicationbusiness
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Altered expression of inflammation-related genes in human carotid atherosclerotic plaques.

2011

Abstract Objective Inflammation is a pivotal process in atherosclerosis development and progression, but the underlying molecular mechanisms remain largely obscure. We have conducted an extensive expression study of atherosclerotic plaques to identify the inflammatory pathways involved in atherosclerosis. Methods We studied 11 human carotid plaques, their respective adjacent regions and 7 control arteries from different subjects. Expression of 92 genes was studied by TaqMan low-density array human inflammation panel. Human aortic endothelial and smooth muscle cells were used for in vitro experiments. Results The mRNA levels of 44/92 genes (48%) differed significantly between the tissues exa…

Carotid Artery DiseasesMalemedicine.medical_specialtyMyocytes Smooth MuscleReceptors ProstaglandinPTGS1InflammationReceptors EpoprostenolSettore MED/22 - Chirurgia VascolareMuscle Smooth VascularCytochrome P-450 Enzyme SystemInternal medicineGene expressionmedicineHumansRNA MessengerReceptors CytokineCells CulturedAgedRegulation of gene expressionInflammationbiologyTumor Necrosis Factor-alphaGene Expression ProfilingMacrophagesEndothelial CellsMiddle AgedCoculture TechniquesPlaque AtheroscleroticGene expression profilingLipoproteins LDLEndocrinologyEicosanoidEicosanoid pathwayGene Expression RegulationItalyAtherosclerosiCase-Control StudiesArachidonate 5-lipoxygenasebiology.proteinCancer researchOxidative streTumor necrosis factor alphaFemaleGene expressionmedicine.symptomInflammation MediatorsCardiology and Cardiovascular MedicineCell Adhesion MoleculesAtherosclerosis
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Contrast-induced Nephropathy after Percutaneous Coronary Intervention in Simple Lesions: Risk Factors and Incidence are Affected by the Definition Ut…

2011

Aim To compare the incidence, and risk factors, in-hospital and at the 18-month prognosis of contrast-induced nephropathy (CIN) according to the definition utilized: as an increase in serum creatinine (Scr) ≥0.5 mg/dL (CIN 1) or as an increase in Scr ≥25% above baseline values (CIN 2). Methods and Results We prospectively evaluated CIN according to two different definitions in 150 patients who underwent percutaneous coronary intervention (PCI) in simple lesions employing a low-medium dose of contrast media. Incidence of CIN was higher using the CIN 2 definition than CIN 1 (9.3% vs. 4%; p=0.0133). Patients with CIN 1 had a higher incidence of chronic kidney disease (CKD) (66.7% vs. 13.9%; p=…

Malemedicine.medical_specialtyAnemiamedicine.medical_treatmentContrast-induced nephropathyUrologyContrast MediaRenal functionurologic and male genital diseasesPercutaneous coronary interventionNephropathychemistry.chemical_compoundContrast induced nephropathyRisk FactorsInternal MedicinemedicineHumansProspective StudiesAngioplasty Balloon CoronaryRenal Insufficiency ChronicneoplasmsAgedCreatininecontrast induced nephropathy percutaneous coronary interventionbusiness.industryIncidenceIncidence (epidemiology)virus diseasesPercutaneous coronary interventionAnemiaGeneral MedicineMiddle Agedmedicine.diseasefemale genital diseases and pregnancy complicationsSurgerysurgical procedures operativeItalychemistryCreatinineFemaleKidney DiseasesbusinessKidney diseaseInternal Medicine
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High-energy devices in different surgical settings: lessons learnt from a full health technology assessment report developed by SICE (Società Italian…

2022

Background The present paper aims at evaluating the potential benefits of high-energy devices (HEDs) in the Italian surgical practice, defining the comparative efficacy and safety profiles, as well as the potential economic and organizational advantages for hospitals and patients, with respect to standard monopolar or bipolar devices. Methods A Health Technology Assessment was conducted in 2021 assuming the hospital perspective, comparing HEDs and standard monopolar/bipolar devices, within eleven surgical settings: appendectomy, hepatic resections, colorectal resections, cholecystectomy, splenectomy, hemorrhoidectomy, thyroidectomy, esophago-gastrectomy, breast surgery, adrenalectomy, and p…

High-energy deviceEconomic analysiMultidimensional evaluationEconomic analysisHTASurgeryBipolar deviceBipolar device; Economic analysis; HTA; High-energy device; Monopolar device; Multidimensional evaluationMonopolar device
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Embolization of a Symptomatic Pseudoaneurysm Developing after Transplant Nephrectomy

2013

Malemedicine.medical_specialtybusiness.industrymedicine.medical_treatmentGeneral MedicineMiddle Agedmedicine.diseaseEmbolization TherapeuticKidney TransplantationNephrectomySurgeryTransplant nephrectomyPseudoaneurysmPostoperative ComplicationsInternal MedicineHumansMedicineEmbolizationbusinessAneurysm FalseInternal Medicine
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Managing Peripheral Artery Disease in Diabetic Patients: A Questionnaire Survey from Vascular Centers of the Mediterranean Federation for the Advanci…

2020

Background The Mediterranean Federation for the Advancing of Vascular Surgery (MeFAVS) was founded on October 1, 2018, to enhance cooperation among vascular professionals within Mediterranean countries. Due to its prominent social and economic impact on national health systems, diabetic arteriopathy has been selected as the very first topic to be investigated by the federation. Methods MeFAVS members were asked to reply to a questionnaire on the management of diabetic ischemic foot. Results were collected and analyzed statistically. The questionnaire consisted of 15 multiple choice answers regarding diabetic foot (DF) diagnosis and treatment. The questionnaire was submitted to 21 centers on…

medicine.medical_treatmentPsychological intervention030204 cardiovascular system & hematologyvascular surgerySettore MED/22 - Chirurgia Vascolare030218 nuclear medicine & medical imagingWound care0302 clinical medicineIschemiaPractice Patterns Physicians'Response rate (survey)Practice Patterns Nurses'diabetesMediterranean RegionEndovascular Proceduresvascular medicineGeneral MedicineTreatment OutcomeCardiology and Cardiovascular MedicineVascular Surgical Proceduresdiabetic footmanagementSpecializationReoperationmedicine.medical_specialtyRevascularizationNurse's RoleAmputation Surgical03 medical and health sciencesperipheral arterial diseaseMediterranean Seamedicineperipheral arterial disease; diabetes; vascular medicine; vascular surgeryHumansTrainingHealthcare DisparitiesEndovascular Surgery; Mediterranean Sea; Training; Vascular SurgeryPhysician's RolePatient Care TeamWound Healingbusiness.industryGeneral surgeryVascular surgerymedicine.diseaseDiabetic footAmputationHealth Care SurveysOrthopedic surgeryEndovascular SurgerySurgerybusinesswound careAnnals of Vascular Surgery
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Endovascular versus open surgical repair of abdominal aortic aneurysm with concomitant malignancy

2007

Background The management of patients with abdominal aortic aneurysm (AAA) and concurrent malignancy is controversial. This study retrospectively assessed the outcome of endovascular repair (EVAR) and open repair (OR) for the treatment of AAA in patients undergoing curative treatment for concomitant malignancies. Methods All patients who underwent surgery for a nonruptured infrarenal AAA of ≥5.5 cm and concomitant malignancy between 1997 and 2005 were retrospectively reviewed. Results Identified were 25 patients (22 men; mean age, 70.3 years) with nonruptured infrarenal AAA of ≥5.5 cm (mean size, 6.4 cm) and concomitant malignancy amenable for curative treatment. EVAR was used to treat 11 p…

Malemedicine.medical_specialtyTime FactorsTime FactorKaplan-Meier EstimateMalignancySettore MED/22 - Chirurgia VascolareFollow-Up StudieAortic aneurysmAneurysmPostoperative Complicationsabdominal aortic aneurysmRetrospective StudieNeoplasmsmedicineHumansEVARAgedRetrospective StudiesAged 80 and overbusiness.industryMortality rateOpen repairGreat BritainRetrospective cohort studyLength of StayMiddle Agedmedicine.diseaseAbdominal aortic aneurysmUnited KingdomSurgeryTreatment OutcomeItalyConcomitantNeoplasmFemaleSurgeryRadiologyPostoperative ComplicationbusinessCardiology and Cardiovascular MedicineVascular Surgical ProceduresAbdominal surgeryHumanAortic Aneurysm AbdominalFollow-Up StudiesmalignancyJournal of Vascular Surgery
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Ureteroiliac Artery Fistula in a Young Woman with Short Bowel Syndrome for Radiation Enteritis

2010

Ureteral-iliac artery fistula is a rare and potentially life-threatening complication, typically occurring after radiation therapy in already surgically treated cancer patients. This case report describes the diagnostic challenges and the successful management, with the positioning of an intra-arterial prosthesis, of a fistula between the internal iliac artery and the left ureter presenting as massive hematuria in a young woman with history of total colectomy and pelvic radiotherapy for rectal cancer and subsequent wide ileal resections and bilateral ureteral stent positioning for radiation enteritis. Ureteroiliac artery fistulas require a prompt diagnosis and intervention, to avoid life th…

medicine.medical_specialtymedicine.medical_treatmentFistulalcsh:MedicineCase Reportshort bowel syndromeSettore MED/22 - Chirurgia Vascolaremedicine.arterymedicineRadiation Enteritisbusiness.industrylcsh:RUreteroiliac artery fistularadiation enteritis.StentGeneral Medicinemedicine.diseaseShort bowel syndromeHematuria Radiation Enteritis Short Bowel Syndrome Ureteroarterial fistula.Internal iliac arterySurgeryRadiation therapymedicine.anatomical_structureComplicationbusinessArteryCase Reports in Medicine
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Decreased Paraoxonase-2 Expression in Human Carotids During the Progression of Atherosclerosis

2008

Objective— Many gene products involved in oxidation and inflammation are implicated in the pathogenesis of atherosclerosis. We investigated paraoxonase 2 (PON2), 5-lipoxygenase (5-LO), and 5-LO activating protein (FLAP) expression and malondialdehyde (MDA) levels in carotid lesions to assess their involvement in plaque formation. Methods and Results— We measured gene expression and MDA levels in atherosclerotic plaques from 59 patients undergoing carotid endarterectomy, and in plaque-adjacent tissue from 41/59 patients. Twenty-three fetal carotids and 6 mammary arteries were also investigated. Real-time polymerase chain reaction and immunohistochemistry revealed decreased PON2 expression i…

MalePathologymedicine.medical_specialtycarotid plaquemedicine.medical_treatment5-Lipoxygenase-Activating ProteinsInflammationCarotid endarterectomySettore MED/22 - Chirurgia VascolareRisk AssessmentSensitivity and SpecificitySeverity of Illness Indexparaoxonase 2 (PON2PathogenesisCohort StudiesTissue Culture TechniquesatherosclerosiPredictive Value of TestsGene expressionmedicineHumansCarotid StenosisMammary ArteriesAgedoxidative streEndarterectomy CarotidArachidonate 5-Lipoxygenasebusiness.industryVascular diseaseAryldialkylphosphataseMembrane ProteinsMiddle Agedmedicine.diseaseAtherosclerosismedicine.anatomical_structureCarotid ArteriesGene Expression RegulationCirculatory systemDisease ProgressionImmunohistochemistryFemalemedicine.symptomCardiology and Cardiovascular MedicinebusinessCarrier Proteinsfetal carotid and mammary arteryBiomarkersBlood vessel
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Single-centre experience and preliminary Results of intravascular ultrasound in endovascular aneurysm repair

2019

Background Intravascular ultrasound (IVUS) has been introduced as diagnostic adjunct to provide new insights into the diagnosis and therapy of vascular disease. Herein, we compared the outcomes of conventional endovascular aneurysm repair (EVAR) and EVAR with IVUS in patients presenting with infrarenal abdominal aortic aneurysm using a propensity-matched cohort. Methods From May 2013 to August 2017, 221 patients were retrospectively analyzed. Of that, 122 patients were eligible for inclusion and underwent propensity score matching. Perioperative mortality and morbidity, renal function impairment, endoleak incidence, mean contrast medium usage, operative time, radiation exposure (including f…

MaleTime Factorsmedicine.medical_treatmentContrast MediaPredictive Value of TestEndovascular aneurysm repairSettore MED/22 - Chirurgia VascolareAortic aneurysmRetrospective StudieRisk FactorsIntravascular ultrasoundFluoroscopyAged 80 and overmedicine.diagnostic_testEndovascular ProceduresGeneral MedicineMiddle AgedRadiation ExposureAbdominal aortic aneurysm2746 SurgeryTreatment OutcomeItalyFemaleRadiologyCardiology and Cardiovascular Medicinerenal function impairmentHumanPreliminary Datamedicine.medical_specialtyTime Factor610 Medicine & healthRadiation DosageAortography2705 Cardiology and Cardiovascular Medicineintravascular ultrasoundBlood Vessel Prosthesis ImplantationEndovascular aneurysm repaircontrast mediumPredictive Value of Testsmedicinefluoroscopy timeHumansUltrasonography InterventionalAgedRetrospective StudiesEndovascular Procedurebusiness.industryRisk FactorAngiography Digital SubtractionPerioperativeDigital subtraction angiographymedicine.disease10020 Clinic for Cardiac SurgeryAngiographySurgerybusinessAortic Aneurysm Abdominal
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