0000000000158227
AUTHOR
A. Rodríguez
NEXT-100 Technical Design Report (TDR). Executive summary
[EN] In this Technical Design Report (TDR) we describe the NEXT-100 detector that will search for neutrinoless double beta decay (ßß0v) in 136XE at the Laboratorio Subterráneo de Canfranc (LSC), in Spain. The document formalizes the design presented in our Conceptual Design Report (CDR): an electroluminescence time projection chamber, with separate readout planes for calorimetry and tracking, located, respectively, behind cathode and anode. The detector is designed to hold a maximum of about 150 kg of xenon at 15 bar, or 100 kg at 10 bar. This option builds in the capability to increase the total isotope mass by 50% while keeping the operating pressure at a manageable level. The readout pla…
Cueva de El Toro (Antequera, Malaga-Spain): a Neolithic stockbreeding community in the Andalusian region, between the 6th and 3th millennia BC
The occupation evidence shown by the cave El Toro, is that of a unique stockbreeding community in the Andalusian region. The calibrated dates for this occupation period go from the second quarter of the sixth millennium up to the second millennium BP. There is also evidence of occasional occupation throughout later millennia up to the Hispano-Muslim period. The nature of thisoccupation is determined by the close link between the cave and the community which occupied it, both continuously and periodically. Throughout the occupation levels, the community's skillful control of technical processesand its remarkable knowledge on how to transform local primary resources, have shown that this comm…
Accompagner les réseaux DEPHY-FERME et DEPHY EXPE dans la caractérisation de l’effet des systèmes de culture sur la flore adventice
To characterize weed pressure in agricultural fields of the DEPHY Ecophyto networks, the "weeds" working group of the CASIMIR project, helped by crop and weed experts working for the french crop institutes, developed two methods (CASIMIR DEPHYFARM and CASIMIR DEPHYEXPE) to survey weeds in main crops. The objectives of these methods are: (i) with shortterm concern, assess the efficacy of farming practices to manage weeds within the crop season, (ii) with longterm concern, assess the effect of cropping system (farming practices and crop sequence) on the dynamic of the weed communities. The CASIMIR DEPHYFARM method is based on walk away surveys made within a 2000m² reference plot where t…
SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study
Abstract Background Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18–49, 50–69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty. Results NNVs were more favourable in su…
Initial results of NEXT-DEMO, a large-scale prototype of the NEXT-100 experiment
NEXT-DEMO is a large-scale prototype of the NEXT-100 detector, an electroluminescent time projection chamber that will search for the neutrinoless double beta decay of Xe-136 using 100-150 kg of enriched xenon gas. NEXT-DEMO was built to prove the expected performance of NEXT-100, namely, energy resolution better than 1% FWHM at 2.5MeV and event topological reconstruction. In this paper we describe the prototype and its initial results. A resolution of 1.75% FWHM at 511 keV (which extrapolates to 0.8% FWHM at 2.5 MeV) was obtained at 10 bar pressure using a gamma-ray calibration source. Also, a basic study of the event topology along the longitudinal coordinate is presented, proving that it…
Near-intrinsic energy resolution for 30-662 keV gamma rays in a high pressure xenon electroluminescent TPC
We present the design, data and results from the NEXT prototype for Double Beta and Dark Matter (NEXT-DBDM) detector, a high-pressure gaseous natural xenon electroluminescent time projection chamber (TPC) that was built at the Lawrence Berkeley National Laboratory. It is a prototype of the planned NEXT-100 Xe-136 neutrino-less double beta decay (0 nu beta beta) experiment with the main objectives of demonstrating near-intrinsic energy resolution at energies up to 662 keV and of optimizing the NEXT-100 detector design and operating parameters. Energy resolutions of similar to 1% FWHM for 662 keV gamma rays were obtained at 10 and 15 atm and similar to 5% FWHM for 30 keV fluorescence xenon X-…
Search forReCQL4mutations in 39 patients genotyped for suspected Rothmund-Thomson/Baller-Gerold syndromes
Three overlapping conditions, namely Rothmund-Thomson (RTS), Baller-Gerold (BGS) and RAPADILINO syndromes, have been attributed to RECQL4 mutations. Differential diagnoses depend on the clinical presentation, but the numbers of known genes remain low, leading to the widespread prescription of RECQL4 sequencing. The aim of our study was therefore to determine the best clinical indicators for the presence of RECQL4 mutations in a series of 39 patients referred for RECQL4 molecular analysis and belonging to the RTS (27 cases) and BGS (12 cases) spectrum. One or two deleterious RECQL4 mutations were found in 10/27 patients referred for RTS diagnosis. Clinical and molecular reevaluation led to a…
Comparison of European ICU patients in 2012 (ICON) versus 2002 (SOAP)
Purpose: To evaluate differences in the characteristics and outcomes of intensive care unit (ICU) patients over time. Methods: We reviewed all epidemiological data, including comorbidities, types and severity of organ failure, interventions, lengths of stay and outcome, for patients from the Sepsis Occurrence in Acutely ill Patients (SOAP) study, an observational study conducted in European intensive care units in 2002, and the Intensive Care Over Nations (ICON) audit, a survey of intensive care unit patients conducted in 2012. Results: We compared the 3147 patients from the SOAP study with the 4852 patients from the ICON audit admitted to intensive care units in the same countries as those…
A VR-based serious game to regulate joy in adolescents: A comparison of different devices
Adolescence is a crucial period to learn Emotional Regulation (ER) strategies to prevent future psychological problems. This work is aimed to test the efficacy of GameTeen System (GT-System), a serious game that teaches ER strategies to regulate joy (VAS scale) and perceived arousal (FAS scale) in a non-clinical sample of adolescents. We conducted a between-participants experiment in which participants (N = 63) played a joy induction game, and then an ER game using one of three types of devices (computer, smartphone, and RGB-D camera). Results revealed that GT-System was only effective in increase perceived arousal after the joy induction game and decrease after the ER game. Statistically s…
Ionization and scintillation response of high-pressure xenon gas to alpha particles
High-pressure xenon gas is an attractive detection medium for a variety of applications in fundamental and applied physics. In this paper we study the ionization and scintillation detection properties of xenon gas at 10 bar pressure. For this purpose, we use a source of alpha particles in the NEXT-DEMO time projection chamber, the large scale prototype of the NEXT-100 neutrinoless double beta decay experiment, in three different drift electric field configurations. We measure the ionization electron drift velocity and longitudinal diffusion, and compare our results to expectations based on available electron scattering cross sections on pure xenon. In addition, two types of measurements add…
Fungal planet description sheets : 1042-1111
Novel species of fungi described in this study include those from various countries as follows: Antarctica, Cladosporium arenosum from marine sediment sand. Argentina, Kosmimatamyces alatophylus (incl. Kosmimatamyces gen. nov.) from soil. Australia, Aspergillus banksianus, Aspergillus kumbius, Aspergillus luteorubrus, Aspergillus malvicolor and Aspergillus nanangensis from soil, Erysiphe medicaginis from leaves of Medicago polymorpha, Hymenotorrendiella communis on leaf litter of Eucalyptus bicostata, Lactifluus albopicri and Lactifluus austropiperatus on soil, Macalpinomyces collinsiae on Eriachne benthamii, Marasmius vagus on soil, Microdochium dawsoniorum from leaves of Sporobolus natale…