Amperometric Biosensor and Front-End Electronics for Remote Glucose Monitoring by Crosslinked PEDOT-Glucose Oxidase
Focusing on the interplay between interface chemistry, electrochemistry, and integrated electronics, we show a novel low-cost and flexible biosensing platform for continuous glucose monitoring. The amperometric biosensing system features a planar three-electrode structure on a plastic substrate, and a wireless near-field communication-powered electronic system performing sensor analog front-end, A/D conversion, digital control, and display tasks. The working electrode is made of electropolymerized poly (3,4-ethylenedioxythiophene) film onto a polyethylene terephthalate/gold electrode followed by immobilization of cross-linked glucose oxidase by glutaraldehyde. The advantages offered by such…
Power losses comparison between Silicon Carbide and Silicon devices for an isolated DC-DC converter
In recent years, new efficient power devices have been implemented. Silicon Carbide has replaced silicon as regards the production and the utilization of many devices, such as MOSFETs, diodes, IGBTs and many others. SiC devices are characterized by a low reverse recovery charge, high carrier saturation velocity, by which it is possible to work at high frequency, and high breakdown voltage. Thanks to the great thermal conductivity and the wide bandgap, these devices can operate at high temperature and reach high voltages and currents. What is important to stress is the fact that power losses in SiC devices are lower than the silicon ones. These are the reasons why these devices are utilized …
PPG/ECG Multisite Combo System Based on SiPM Technology
Two versions of a PPG/ECG combined system have been realized and tested. In a first version a multisite system has been equipped by integrating 3 PPG optodes and 3 ECG leads, whereas in another setup a portable version has been carried out. Both versions have been realized by equipping the optical probes with SiPM detectors. SiPM technology is expected to bring relevant advantages in PPG systems and overcome the limitations of physiological information extracted by state of the art PPG, such as poor sensitivity of detectors used for backscattered light detection and motion artifacts seriously affecting the measurements repeatability and pulse waveform stability. This contribution presents t…
Low invasive multisensor acquisition system for real-time monitoring of cardiovascular and respiratory parameters
The recent advances in multiparametric monitoring of biosignals and management of big data prompt for the development of devices and techniques for the extraction of indicators with physiological relevance. In this context, we have designed and realized a portable electronic system, equipped with simple biomedical sensors, able to synchronously record multiple electrocardiographic (ECG), photoplethysmographic (PPG) and breathing signals, for carrying out a non-invasive monitoring of several cardiovascular parameters. In this work, we show the results of preliminary measurements performed following a specific physiological protocol (i.e., deep breathing with 10 s per cycle). The system allow…
Fiberless, Multi-Channel fNIRS-EEG System Based on Silicon Photomultipliers: Towards Sensitive and Ecological Mapping of Brain Activity and Neurovascular Coupling
Portable neuroimaging technologies can be employed for long-term monitoring of neurophysiological and neuropathological states. Functional Near-Infrared Spectroscopy (fNIRS) and Electroencephalography (EEG) are highly suited for such a purpose. Their multimodal integration allows the evaluation of hemodynamic and electrical brain activity together with neurovascular coupling. An innovative fNIRS-EEG system is here presented. The system integrated a novel continuous-wave fNIRS component and a modified commercial EEG device. fNIRS probing relied on fiberless technology based on light emitting diodes and silicon photomultipliers (SiPMs). SiPMs are sensitive semiconductor detectors, whose large…
Simulation of parasitic effects on Silicon Carbide devices for automotive electric traction
Wide Band Gap (WBG) semiconductors are increasingly addressed towards Electric Vehicle (EV) applications, due to their significant advantages in terms of high-voltage and low-losses performances, suitable for high power applications. Nevertheless, the packaging in WBG devices represents a challenge for designers due to the notable impact that inductive and capacitive parasitic components can bring in high switching frequency regime in terms of noise and power losses. In this paper, a comparison between conventional Silicon (Si) and emerging Silicon-Carbide (SiC) power switching devices is presented. The effects of inductive parasitic effects and switching frequency are investigated in simul…
A prototypal PCB board for the EMI characterization of SiC-based innovative switching devices
In this paper, a preliminary PCB board for the electromagnetic interference (EMI) characterization of innovative silicon-carbide (SiC) based switching devices is presented. Packaging technological issues can determine hurdles in the high-frequency switching and high power regime where wide band gap semiconductors are intended today for Electric Vehicle (EV) applications. In particular, the parasitic inductances that emerge in such devices, must be assessed, by using e.g. EMI techniques. In this specific case, the EMI characterization is supposed to be carried out in a semi-anechoic chamber, available at the University of Palermo (UNIPA), to assess the electromagnetic disturbances according …
A Compact SPICE Model for Organic TFTs and Applications to Logic Circuit Design
This work introduces a compact DC model developed for organic thin film transistors (OTFTs) and its SPICE implementation. The model relies on a modified version of the gradual channel approximation that takes into account the contact effects, occurring at nonohmic metal/organic semiconductor junctions, modeling them as reverse biased Schottky diodes. The model also comprises channel length modulation and scalability of drain current with respect to channel length. To show the suitability of the model, we used it to design an inverter and a ring oscillator circuit. Furthermore, an experimental validation of the OTFTs has been done at the level of the single device as well as with a discrete-…
Ostruzione polmonare ed aritmia respiratoria
Il monitoraggio di pazienti tramite segnali fotopletismografici (PhotoPlethysmoGram, PPG) acquisiti sul polso, arteria radiale, piuttosto che sulla punta dell’indice, permette di ottenere un segnale più stabile e con maggiori informazioni, come la gittata cardiaca, la durata della contrazione ventricolare e la chiusura dell’aorta. In questo lavoro è presentata un’attività preliminare per rilevare condizioni come l’ostruzione polmonare e le apnee notturne. Si è indagato l’andamento dell’aritmia respiratoria in relazione ad eventuali difficoltà respiratorie. Per il momento ci si è limitati ad osservare soggetti sani e l’ostruzione è stata simulata facendo respirare i soggetti attraverso una c…
Wearable, Fiber-less, Multi-Channel System for Continuous Wave Functional Near Infrared Spectroscopy Based on Silicon Photomultipliers Detectors and Lock-In Amplification
Development and in-vivo validation of a Continuous Wave (CW) functional Near Infrared Spectroscopy (fNIRS) system is presented. The system is wearable, fiber-less, multi-channel (16×16, 256 channels) and expandable and it relies on silicon photomultipliers (SiPMs) for light detection. SiPMs are inexpensive, low voltage and resilient semiconductor light detectors, whose performances are analogous to photomultiplier tubes (PMTs). The advantage of SiPMs with respect to PMTs is that they allow direct contact with the scalp and avoidance of optical fibers. In fact, the coupling of SiPMs and light emitting diodes (LEDs) allows the transfer of the analog signals to and from the scalp through thin …