0000000000276965

AUTHOR

Stefan Zielen

0000-0003-1204-0627

showing 4 related works from this author

Comparison of bronchial and nasal allergen provocation in children and adolescents with bronchial asthma and house dust mite sensitization.

2019

Background Bronchial allergen provocation (BAP) is an established tool for the diagnosis of allergy in patients with asthma, but its use is limited by the potential risk of severe asthmatic reactions. Nasal provocation testing (NPT) may be an alternative safe method and does not require sophisticated equipment. Objective The aim of this prospective study was to evaluate the concordance of both methods in patients with asthma and house dust mite (HDM) sensitization. Methods A total of 112 patients with HDM sensitization underwent BAP and had the following parameters analysed: decrease in FEV1, exhaled NO, and total and specific IgE. Within 12 weeks, NPT with HDM was performed in 74 patients …

Malemedicine.medical_specialtyAllergyNasal Provocation TestsAdolescentmedicine.medical_treatmentImmunologyProvocation testmedicine.disease_causeGastroenterologyNasal provocation testBronchial Provocation Tests03 medical and health sciences0302 clinical medicineAllergenInternal medicinemedicineHypersensitivityImmunology and AllergyAnimalsHumans030212 general & internal medicineAntigens DermatophagoidesProspective StudiesChildSensitizationAsthmaHouse dust miterhinorrheabiologybusiness.industryPyroglyphidaeImmunoglobulin Emedicine.diseasebiology.organism_classificationAsthmamedicine.anatomical_structure030228 respiratory systemPediatrics Perinatology and Child HealthFemaleImmunizationmedicine.symptombusinessPediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and ImmunologyREFERENCES
researchProduct

Children Below Five Years Of Age Can Handle Respimat® Soft MistTM Inhaler

2010

medicine.medical_specialtyPediatricsRespimatbusiness.industryInhalerPhysical therapyMedicinebusinessD57. PEDIATRIC AIRWAY DISEASES: MANAGEMENT
researchProduct

Nasal IgE in subjects with allergic and non-allergic rhinitis

2020

Abstract Purpose The prevalence of "ocal allergic rhinitis" within individuals suffering from perennial rhinitis remains uncertain, and patients usually are diagnosed with non-allergic rhinitis. The aim of this study was to evaluate the prevalence of a potential "local allergic rhinitis" in subjects suffering from non-allergic rhinitis in a non-selected group of young students. Methods 131 students (age 25.0 ± 5.1 years) with a possible allergic rhinitis and 25 non-allergic controls without rhinitis symptoms (age 22.0 ± 2.0 years) were recruited by public postings. 97 of 131 students with rhinitis were tested positive (≥3 mm) to prick testing with 17 frequent allergens at visit 1. Twenty-fo…

AllergyNon-allergic rhinitismedicine.medical_treatmentImmunoglobulin EAR + HDM allergic rhinitis with house dust mite allergyAllergic rhinitisHDM house dust miteNPT nasal provocation testsAR allergic rhinitis0302 clinical medicineISAAC International Study of Asthma and Allergies in Childhood questionnaireNARES non-allergic rhinitis with eosinophilia-syndromeMedicine and Health SciencesImmunology and Allergy030223 otorhinolaryngologyeducation.field_of_studybiologymedicine.diagnostic_testRadioallergosorbent testsIgE allergen-specific IgENon-allergicD1 Dermatophagoides pteronyssinusPREVALENCED2 Dermatophagoides farinaeLAR local allergic rhinitisPROVOCATION TESTSPulmonary and Respiratory Medicinelcsh:Immunologic diseases. AllergyLOCAL IGEImmunologyPopulationPATHOPHYSIOLOGYNon-allergic-rhinitisLocal allergic rhinitisGCP Good Clinical PracticeDIAGNOSISNasal provocation testArticleSECRETIONS03 medical and health sciencesFEV1/FVC ratiorhinitismedicineddc:610educationHouse dust mitebusiness.industryFEV1 forced expiratory volume in one secondRAST Radioallergosorbent Testbiology.organism_classificationmedicine.disease030228 respiratory systemHouse dust mite allergyPNIF peak nasal inspiratory flowImmunologyFVC forced vital capacitybiology.proteinbusinessSD standard deviationlcsh:RC581-607Local IgESPT skin prick testWorld Allergy Organization Journal
researchProduct

Safety of anti-IgE treatment with omalizumab in children with seasonal allergic rhinitis undergoing specific immunotherapy simultaneously

2009

Kamin W, Kopp MV, Erdnuess F, Schauer U, Zielen S, Wahn U. Safety of anti-IgE treatment with omalizumab in children with seasonal allergic rhinitis undergoing specific immunotherapy simultaneously. Pediatr Allergy Immunol 2010: 21: e160–e165. © 2009 John Wiley & Sons A/S Introduction  Seasonal allergic rhinitis (SAR) affects at least 10–25% of the Caucasian race and about 40% of patients are children. Standard treatment of SAR is specific immunotherapy (SIT), but anti-allergic drugs can significantly enhance efficacy of SIT. One candidate is the humanized monoclonal anti-IgE antibody omalizumab. Material and Methods  Randomized, double-blind, placebo-controlled, multi-centre trial in German…

Malemedicine.medical_specialtyAllergyAdolescentImmunologyOmalizumabOmalizumabAntibodies Monoclonal HumanizedPoaceaePlacebolaw.inventionRandomized controlled triallawGermanyInternal medicinemedicineHumansImmunology and AllergyChildAdverse effectAsthmabusiness.industryStandard treatmentAntibodies MonoclonalRhinitis Allergic SeasonalAllergensImmunoglobulin Emedicine.diseaseAntibodies Anti-IdiotypicSurgeryTolerabilityPediatrics Perinatology and Child HealthFeasibility StudiesPollenDrug Therapy CombinationFemaleImmunotherapybusinessmedicine.drugPediatric Allergy and Immunology
researchProduct