Blunted cortisol response to stress in patients with eating disorders: Its association to bulimic features
ObjectiveClinical research on cortisol response to stress in patients with eating disorders has provided controversial and even contradictory results. As this might be the consequence of the inclusion in the studies of heterogeneous clinical populations, 3 highly selected samples were studied. MethodsDexamethasone suppression test was performed on 15 restricting anorexia nervosa patients without history of bulimia nervosa (BN), 17 BN patients with normal weight and no history of anorexia nervosa, and 22 healthy controls. Three days later, the Trier Social Stress Test was applied, and 8 saliva samples were collected along the trial for cortisol assessment. ResultsWhen the patients were consi…
Papel de la depresión y la impulsividad en la psicopatología de la bulimia nerviosa
Resumen Introduccion El presente estudio trato de analizar el papel de la depresion y la impulsividad en la psicopatologia de la bulimia nerviosa (BN). Materiales y metodos Se examino a 70 mujeres con un diagnostico de bulimia nerviosa basado en la cuarta revision del Manual diagnostico y estadistico de los trastornos mentales (DSM-IV), subtipo purgativo, para los sintomas relacionados con el trastorno de la conducta alimentaria, insatisfaccion corporal, sintomas afectivos, impulsividad y rasgos de personalidad. Para el analisis estadistico se utilizaron metodos de analisis factorial y de modelos de ecuaciones estructurales. Resultados La BN se presento como un proceso que incorporaba 5 dim…
Neurobiological and Clinical Variables Associated with Alcohol Abuse in Bulimia Nervosa
The study was aimed at analysing the reciprocal relationships of several clinical and neurobiological items in order to predict alcohol misuse in patients with bulimia nervosa (BN). Seventy BN patients and 70 healthy controls were assessed for depression, impulsivity, borderline personality traits and self-defeating behaviours using specific scales; serum cortisol and 24-hour urinary excretion of serotonin and 5-hydroxiindolacetic acid were also assessed. The study confirmed the implications of these clinical factors for alcohol misuse in BN patients, but the results suggested that depressive symptoms and hypercortisolism could lie behind these relationships.
The role of depression and impulsivity in the psychopathology of bulimia nervosa.
Introduction: The study aimed to analyze the role of depression and impulsivity in the psychopathology of bulimia nervosa (BN). Materials and methods: Seventy female patients with DSM-IV BN, purging subtype, were assessed for eating-related symptoms, body dissatisfaction, affective symptoms, impulsivity, and personality traits. Factor analysis and structural equation modeling methods were used for statistical analysis. Results: BN appeared as a condition which incorporated 5 general dimensions: a) binge eating and compensatory behaviours; b) restrictive eating; c) body dissatisfaction; d) dissocial personality traits; and e) a cluster of features which was called "emotional instability" The…