0000000000289107

AUTHOR

Romano Lapasin

showing 4 related works from this author

Agarose/κ-carrageenan-based hydrogel film enriched with natural plant extracts for the treatment of cutaneous wounds.

2020

Abstract Hydrogels for complex and chronic wound dressings must be conformable, absorb and retain wound exudates and maintain hydration. They can incorporate and release bioactive molecules that can accelerate the healing process. Wound dressings have to be in contact with the wound and epidermis, even for long periods, without causing adverse effects. Hydrogel dressing formulations based on biopolymers derived from terrestrial or marine flora can be relatively inexpensive and well tolerated. In the present article hydrogel films composed by agarose (1.0 wt%), κ-carrageenan at three different concentrations (0.5, 1.0 and 1.5 wt%) and glycerol (3.0 wt%) were prepared without recourse to cros…

Chronic woundCell Survival02 engineering and technologyCarrageenanBiochemistryAntioxidants03 medical and health scienceschemistry.chemical_compoundMiceStructural BiologymedicineGlycerolAnimalsFibroblastCytotoxicityMolecular Biology030304 developmental biology0303 health sciencesEpidermis (botany)Plant ExtractsSepharoseGeneral MedicineFibroblasts021001 nanoscience & nanotechnologyMethylgalactosidesBandagesBryopsidaElasticityBiomechanical Phenomenamedicine.anatomical_structureAgarose/κ-carrageenan lend Cryphaea heteromalla bryophyte Wound healingchemistrySelf-healing hydrogelsBiophysicsNIH 3T3 CellsAgaroseSettore CHIM/07 - Fondamenti Chimici Delle Tecnologiemedicine.symptomSwelling0210 nano-technologyInternational journal of biological macromolecules
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Recovery from Food Waste-Biscuit Doughs Enriched with Pomegranate Peel Powder as a Model of Fortified Aliment

2022

This research was funded by the "IEV Programme de Cooperation Italie-Tunisie 2014-2020, Re-lancer une nouvelle economie (Re-Ne)". EU project code C-5-3.1-39.

food waste recoveryGeneral Immunology and MicrobiologyPomegranate peelpomegranate peel; fortified food; food waste recoveryfood and beveragesFortified foodSettore CHIM/07 - Fondamenti Chimici Delle TecnologieGeneral Agricultural and Biological SciencesFood waste recoveryGeneral Biochemistry Genetics and Molecular Biologypomegranate peelfortified food
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Physical characterization of alginate-Pluronic F127 gel for endoluminal NABDs delivery

2014

Here we focus the attention on the physical characteristics of a highly biocompatible hydrogel made up of crosslinked alginate and Pluronic F127 (PF127). This is a composite polymeric blend we propose for artery endoluminal delivery of an emerging class of molecules named nucleic acid based drugs (NABDs). The physical characterization of our composite gel, i.e. mesh size distribution and PF127-alginate mutual organization after crosslinking, can significantly determine the NABDs release kinetics. Thus, to explore these aspects, different technical approaches, i.e. rheology, low/high field NMR and TEM, were used. While rheology provided information at the macroscopic and nano-level, the othe…

Materials sciencegel pavingAlginatesKineticsComposite numberNanotechnologyPoloxamerMicellerestenosisRheologyalginateArterial wallMicellesDrug Carriersgel paving; rheology; NMR; alginate; Pluronic; restenosisGeneral ChemistryPluronicPoloxamerCondensed Matter PhysicsNMRCharacterization (materials science)Chemical engineeringSettore CHIM/09 - Farmaceutico Tecnologico ApplicativoSolute diffusionrheologyNABDs release kinetics PF127 alginate gel paved stent artery endoluminal deliveryGels
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Moringa oleifera Leaf Powder as Functional Additive in Cookies to Protect SH-SY5Y Cells

2021

The aim of this work is the evaluation of the addition of Moringa leaf powder (MLP) in cookies in terms of antioxidant properties, dough processability and sensorial properties of the cookies. The total content of biophenols and flavonoids in MLP was detected and the identification of the bioactive molecules was performed by HPLC-ESI-TOF-MS measurements, before and after oven treatment at 180 ◦C for 20 min. After a preliminary evaluation of the MLP water soluble fraction (MLPsf) cytotoxicity, its protective effect against an oxidative injury induced in the SH-SY5Y cells was assessed. Data evidence that the bioactive molecules present in MLPsf are effective in preventing ROS production and i…

TechnologySH-SY5YAntioxidantQH301-705.5QC1-999Bioactive moleculesmedicine.medical_treatmentCytotoxicitymedicine.disease_causeMORINGA OLEIFERA LEAFantioxidant effectsMoringachemistry.chemical_compoundHPLC-ESI-TOF-MS identificationsAntioxidant effects Cytotoxicity HPLC-ESI-TOF-MS identifications Moringa leaf powder Rheologymedicinemoringa leaf powderGeneral Materials ScienceOxidative injuryFood scienceBiology (General)QD1-999InstrumentationFluid Flow and Transfer ProcessesTPhysicsProcess Chemistry and TechnologyGeneral Engineeringfood and beveragesmoringa leaf powder; HPLC-ESI-TOF-MS identifications; cytotoxicity; antioxidant effects; rheology; SEMEngineering (General). Civil engineering (General)Moringa leaf powderComputer Science ApplicationsChemistrychemistryAntioxidant effectsSEMcytotoxicityrheologySettore CHIM/07 - Fondamenti Chimici Delle TecnologieTA1-2040KaempferolRheologyOxidative stress
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