Specific Protein Docking to Chelator Lipid Monolayers Monitored by FT-IR Spectroscopy at the Air–Water Interface

Molecular Recognition-Induced Function and Competitive Replacement by Hydrogen-Bonding Interactions:  Amphiphilic Barbituric Acid Derivatives, 2,4,6-Triaminopyrimidine, and Related Structures at the Air−Water Interface

The phenomenon of molecular recognition inducing further function is common in nature. However, there are few synthetic systems which achieve this cascade type mechanism, and those are generally ca...

Nachweis der spezifischen Proteinadsorption an Chelatorlipidmonoschichten mit FT-IR-Spektroskopie an der Wasser/Luft-Grenzfläche

Micelles, monolayers and biomembranes. By M. N. Jones, D. Chapman, Wiley-Liss, New York 1995, XII, 252 pp., hardcover $69.00, ISBN 0-471-56139-8

Formation of supramolecular aggregates by hydrogen bonding based on bispyrimidine and bisbarbituric acid

Hydrogen bonds between bispyrimidine and bisbarbituric acid in equal molar ratio can lead to the formation of supramolecular aggregates. This is established by TEM, IR and DSC measurements. Additionally, WAXS pattern showed that the aggregate is of laminar structure. Both the hydrolysis of this system and termination of the aggregate's growth were studied.

Molecular Recognition by Hydrogen Bonding in Polyelectrolyte Multilayers

Functional polyanions were prepared by copolymerization of sulfopropyl acrylate and sulfopropyl methacrylate with monomers bearing triaminopyrimidine or barbituric acid functionalities, respectively. Functionalized polyelectrolyte multilayers were assembled from these copolymers by stepwise alternating adsorption with poly(choline methacrylate). These multilayers are suited for molecular recognition of substrates that are complementary to the functional groups incorporated. Thus, multilayers containing triaminopyrimidine moieties selectively bind barbituric acid, and vice versa, when exposed to solutions of the 1:1 complex of barbituric acid and triaminopyrimidine. The molecular recognition…