0000000000339637

AUTHOR

Jenni Leppiniemi

0000-0002-7225-1648

showing 3 related works from this author

Defined-size DNA triple crossover construct for molecular electronics: modification, positioning and conductance properties.

2011

We present a novel, defined-size, small and rigid DNA template, a so-called B-A-B complex, based on DNA triple crossover motifs (TX tiles), which can be utilized in molecular scale patterning for nanoelectronics, plasmonics and sensing applications. The feasibility of the designed construct is demonstrated by functionalizing the TX tiles with one biotin-triethylene glycol (TEG) and efficiently decorating them with streptavidin, and furthermore by positioning and anchoring single thiol-modified B-A-B complexes to certain locations on a chip via dielectrophoretic trapping. Finally, we characterize the conductance properties of the non-functionalized construct, first by measuring DC conductivi…

StreptavidinMaterials scienceMechanical EngineeringCrossoverElectric ConductivityMolecular electronicsConductanceBioengineeringNanotechnologyGeneral ChemistryDNAConductivityMicroscopy Atomic Forcechemistry.chemical_compoundchemistryNanoelectronicsMechanics of MaterialsDielectric SpectroscopyEquivalent circuitNucleic Acid ConformationGeneral Materials ScienceElectrical and Electronic EngineeringElectronicsPlasmonNanotechnology
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Toward Single Electron Nanoelectronics Using Self-Assembled DNA Structure

2016

DNA based structures offer an adaptable and robust way to develop customized nanostructures for various purposes in bionanotechnology. One main aim in this field is to develop a DNA nanobreadboard for a controllable attachment of nanoparticles or biomolecules to form specific nanoelectronic devices. Here we conjugate three gold nanoparticles on a defined size TX-tile assembly into a linear pattern to form nanometer scale isolated islands that could be utilized in a room temperature single electron transistor. To demonstrate this, conjugated structures were trapped using dielectrophoresis for current-voltage characterization. After trapping only high resistance behavior was observed. However…

NanostructureMaterials scienceTransistors Electronicta221Metal NanoparticlesElectronsBioengineeringNanotechnology02 engineering and technology010402 general chemistry01 natural sciencesnanoelectronicsNanobiotechnologyGeneral Materials ScienceA-DNAParticle Sizeta114Mechanical EngineeringTemperatureCoulomb blockadeDNA structureDNAGeneral ChemistryDielectrophoresis021001 nanoscience & nanotechnologyCondensed Matter Physics0104 chemical sciencesCharacterization (materials science)NanoelectronicsColloidal goldGold0210 nano-technologyDimerizationNano Letters
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Growth of immobilized DNA by polymerase: bridging nanoelectrodes with individual dsDNA molecules.

2011

We present a method for controlled connection of gold electrodes with dsDNA molecules (locally on a chip) by utilizing polymerase to elongate single-stranded DNA primers attached to the electrodes. Thiol-modified oligonucleotides are directed and immobilized to nanoscale electrodes by means of dielectrophoretic trapping, and extended in a procedure mimicking PCR, finally forming a complete dsDNA molecule bridging the gap between the electrodes. The technique opens up opportunities for building from the bottom-up, for detection and sensing applications, and also for molecular electronics.

Bridging (networking)Sensing applicationsFOS: Physical sciencesNanotechnology02 engineering and technologyDNA-Directed DNA PolymeraseCondensed Matter - Soft Condensed Matter03 medical and health sciencesMoleculeNanotechnologyGeneral Materials SciencePhysics - Biological PhysicsElectrodesPolymerase030304 developmental biologyDNA PrimersFluorescent Dyes0303 health sciencesbiologyImmobilized DNAta114OligonucleotideChemistryta1182Molecular electronicsDNA021001 nanoscience & nanotechnologyCondensed Matter - Other Condensed MatterBiological Physics (physics.bio-ph)Electrodebiology.proteinSoft Condensed Matter (cond-mat.soft)Gold0210 nano-technologyNucleic Acid Amplification TechniquesOther Condensed Matter (cond-mat.other)Nanoscale
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