0000000000354769

AUTHOR

Richard G. Maroun

showing 4 related works from this author

From waste to health: sustainable exploitation of grape pomace seed extract to manufacture antioxidant, regenerative and prebiotic nanovesicles withi…

2020

AbstractPomace seed extract loaded vesicles were prepared as promising technological and green solution to exploit agri-food wastes and by-products, and develop high value-added products for human health. An antioxidant extract rich in bioactive compounds (epicatechins, catechin, gallic acid, quercetin and procynidins) was obtained from the seeds isolated from the pomace of Cannonau red grape cultivar. The extract was incorporated into phospholipid vesicles ad hoc formulated for intestinal delivery, by combining them, for the first time, whit a maltodextrin (Glucidex). Glucidex-transfersomes, glucidex-hyalurosomes and glucidex-hyalutransferomes were prepared, characterized and tested. Gluci…

0301 basic medicineLimosilactobacillus reuteriAntioxidantmedicine.medical_treatmentlcsh:MedicinePolysorbatesAntioxidantschemistry.chemical_compound0302 clinical medicineRecyclingVitisGallic acidFood scienceHyaluronic AcidHydrogen peroxidelcsh:SciencePhospholipidsDrug CarriersMultidisciplinaryfood and beveragesCatechinMaltodextrinIntestinesPolifenolsColonic NeoplasmsSeedsQuercetinPrebiòticsGrapesArticle03 medical and health sciencesNanocapsulesNanoscience and technologyPolysaccharidesCell Line TumormedicineHumansRaïmsWaste ProductsPlant ExtractsPrebioticlcsh:RPomaceHealth carePolyphenolsGreen Chemistry TechnologyHydrogen PeroxideNanostructuresIntestinal Diseases030104 developmental biologyPrebioticschemistryBiofilmsLiposomeslcsh:Q030217 neurology & neurosurgery
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Extraction, Characterization and Incorporation of Hypericum scruglii Extract in Ad Hoc Formulated Phospholipid Vesicles Designed for the Treatment of…

2020

An extract of Hypericum scruglii, an endangered endemic plant of Sardinia (Italy), was prepared and characterized. It was loaded in special phospholipid vesicles, glycerosomes, which were modified by adding maltodextrin (glucidex) and a polymer (gelatin or hyaluronan). The corresponding liposomes were also prepared and used as reference. The vesicles disclosed suitable physicochemical features for skin delivery. Indeed, their mean diameter ranged from 120 to 160 nm, they were homogeneously dispersed (polydispersity index &le

food.ingredientlcsh:RS1-441Pharmaceutical Science02 engineering and technologyhypericaceaemedicine.disease_cause01 natural sciencesGelatinArticlelcsh:Pharmacy and materia medicagelatinhyaluronanchemistry.chemical_compoundglycerosomesfoodphospholipid vesiclesscratch assayZeta potentialmedicineoxidative stressHydrogen peroxideLiposome010405 organic chemistryVesiclekeratinocyte uptake021001 nanoscience & nanotechnologyMaltodextrinIn vitro0104 chemical scienceschemistryBiophysics0210 nano-technologyOxidative stress
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Optimization of Polyphenols' Recovery from Purple Corn Cobs Assisted by Infrared Technology and Use of Extracted Anthocyanins as a Natural Colorant i…

2022

An ecofriendly extraction technology using infrared (IR) irradiation Ired-Irrad® was applied to purple corn cobs to enhance polyphenol recovery for the first time. The IR extraction efficiency was compared to that of the water bath (WB) method. Response surface methodology (RSM) using a central composite design was conducted to determine the effect of the experimental conditions (extraction time and treatment temperature) and their interactions on the total polyphenol and anthocyanin yields. Optimal extraction of total phenolic compounds (37 mg GAE/g DM) and total monomeric anthocyanins (14 mg C3G/g DM) were obtained at 63 °C for 77 min using IR as an extraction technique and water as a sol…

TechnologyPlant ExtractsOrganic ChemistryBrassica napusPharmaceutical SciencePolyphenolsWaterZea maysAnalytical ChemistryAnthocyaninsBlat de moroChemistry (miscellaneous)Drug DiscoveryMolecular MedicineColorants en els alimentsTecnologia dels alimentsPhysical and Theoretical Chemistrypurple corn cobs; infrared-assisted extraction; response surface methodology; anthocyanins; natural colorant
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The Importance of Developing Electrochemical Sensors Based on Molecularly Imprinted Polymers for a Rapid Detection of Antioxidants

2021

International audience; This review aims to pin out the importance of developing a technique for rapid detection of antioxidants, based on molecular imprinting techniques. It covers three major areas that have made great progress over the years in the field of research, namely: antioxidants characterization, molecular imprinting and electrochemistry, alone or combined. It also reveals the importance of bringing these three areas together for a good evaluation of antioxidants in a simple or complex medium, based on selectivity and specificity. Although numerous studies have associated antioxidants with molecular imprinting, or antioxidants with electrochemistry, but even electrochemistry wit…

0301 basic medicinesol-gel techniquePhysiologyClinical Biochemistryelectrochemical sensorNanotechnologyReviewBiochemistryRapid detection03 medical and health sciences0302 clinical medicine[SDV.IDA]Life Sciences [q-bio]/Food engineering[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular BiologyMolecular Biologyscreen printed electrodesChemistrylcsh:RM1-950Molecularly imprinted polymerCell Biologyradical polymerizationcyclic voltammetrylcsh:Therapeutics. Pharmacologyantioxidants030104 developmental biologyindustrial applicationsmolecular imprintingMolecular imprinting030217 neurology & neurosurgerydifferential pulse voltammetryAntioxidants
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