0000000000355125

AUTHOR

Alessandro Mezzani

0000-0003-1595-6227

showing 2 related works from this author

Aerobic training and angiogenesis activation in patients with stable chronic heart failure: a preliminary report.

2013

The pathophysiology of chronic heart failure (CHF) involves multiple hystologic and molecular alterations. To determine the effects of physical training on circulating endothelial progenitor cells (EPCs), angiogenesis (angiogenin, angiopoietin-1 and -2, VEGF, Tie-2, SDF-1α) and inflammation (IL-6, CRP), we compared data obtained from 11 CHF pts before and after 3 months aerobic exercise training, to those from 10 non trained CHF pts (CHF-C group, age 64 + 2 years, NYHA 2). At the end of the study, EPCs count and AP-2 serum levels significantly increased in the CHF-TR group. These preliminary data suggest a significant effect of even a short program of physical training on angiogenic activat…

Malemedicine.medical_specialtyAngiogeninBrachial ArteryAngiogenesisHealth Toxicology and MutagenesisClinical BiochemistryNeovascularization PhysiologicCardiovascular disease growth factors/cytokines/inflammatory mediators sports science/exerciseInflammationPilot ProjectsBiochemistryNeovascularizationInternal medicinemedicineAerobic exerciseHumanscardiovascular diseasesProspective StudiesEndothelial dysfunctionAngiogenic ProteinsExerciseAgedHeart Failurebusiness.industryStem CellsEndothelial CellsStroke VolumeStroke volumeMiddle Agedmedicine.diseaseSettore MED/11 - Malattie Dell'Apparato CardiovascolareExercise TherapyVasodilationTreatment OutcomeHeart failureImmunologyChronic Diseasecardiovascular systemCardiologymedicine.symptombusinessBiomarkerscirculatory and respiratory physiologyBiomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals
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The predictive role of C-reactive protein in patients with hypertension and subclinical atherosclerosis.

2009

Recent guidelines published by the joint European Society of Hypertension/European Society of Cardiology have suggested the inclusion of C-reactive protein (CRP) in the standard assessment of cardiovascular risk in hypertensive patients, but little data is available on the role of CRP in patients with carotid lesions. We studied in 472 subjects, 236 with and 236 without hypertension, gender- and age-matched, with and without early stages of atherosclerosis (e.g. those with asymptomatic intima-media thickness >0.9 mm), the influence of all the other traditional cardiovascular risk factors (e.g. older age, male gender, obesity, diabetes, smoking habit, family history of coronary artery diseas…

Malemedicine.medical_specialtySettore MED/09 - Medicina InternaInflammationAsymptomaticCoronary artery diseasePredictive Value of TestsRisk FactorsInternal medicineDiabetes mellitusCRP Hypertension Subclinical Atherosclerosis atherosclerosisInternal MedicinemedicineHumansIn patientFamily historyAgedbiologybusiness.industryC-reactive proteinMiddle Agedmedicine.diseaseC-reactive protein hypertension inflammation event atherosclerosisAtherosclerosisObesitySettore MED/11 - Malattie Dell'Apparato CardiovascolareCerebrovascular DisordersC-Reactive ProteinCase-Control StudiesHypertensionCardiologybiology.proteinFemalemedicine.symptombusinessBiomarkersFollow-Up StudiesInternal medicine journal
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