0000000000470951

AUTHOR

Magdalena Bielacz

showing 3 related works from this author

Usefulness of Cerebral Oximetry in TBI by NIRS

2021

Measurement of cerebral oximetry by near-infrared spectroscopy provides continuous and non-invasive information about the oxygen saturation of haemoglobin in the central nervous system. This is especially important in the case of patients with traumatic brain injuries. Monitoring of cerebral oximetry in these patients could allow for the diagnosis of inadequate cerebral oxygenation caused by disturbances in cerebral blood flow. It could enable identification of episodes of hypoxia and cerebral ischemia. Continuous bedside measurement could facilitate the rapid diagnosis of intracranial bleeding or cerebrovascular autoregulation disorders and accelerate the implementation of treatment. Howev…

medicine.medical_specialtynear-infrared spectroscopyTraumatic brain injuryCentral nervous systemintracranial pressureIschemiaReview03 medical and health sciences0302 clinical medicineInternal medicinemedicineCerebral oximetryIntracranial pressureOxygen saturation (medicine)business.industrytraumatic brain injurycerebrovascular autoregulationRcerebral oximetry030208 emergency & critical care medicineGeneral MedicineHypoxia (medical)medicine.diseasemedicine.anatomical_structureCerebral blood flowCardiologyMedicinemedicine.symptombusiness030217 neurology & neurosurgeryJournal of Clinical Medicine
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Suppression of Electrographic Seizures Is Associated with Amelioration of QTc Interval Prolongation in Patients with Traumatic Brain Injury.

2021

Introduction: Disorders in electroencephalography (EEG) are commonly noted in patients with traumatic brain injury (TBI) and may be associated with electrocardiographic disturbances. Electrographic seizures (ESz) are the most common features in these patients. This study aimed to explore the relationship between ESz and possible changes in QTc interval and spatial QRS-T angle both during ESz and after ESz resolution. Methods: Adult patients with TBI were studied. Surface 12-lead ECGs were recorded using a Cardiax device during ESz events and 15 min after their effective suppression using barbiturate infusion. The ESz events were diagnosed using Masimo Root or bispectral index (BIS) devices.…

medicine.medical_specialtyTraumatic brain injurymedicine.drug_classseizureQTc intervalElectroencephalographyQT intervalArticlebrain–heart interactionInternal medicinemedicineIn patientcardiovascular diseasesCerebral oximetrymedicine.diagnostic_testbusiness.industryspatial QTS-T angletraumatic brain injuryRGeneral Medicinemedicine.diseaseBarbiturateBispectral indexQtc interval prolongationCardiologyMedicinebusinessJournal of clinical medicine
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Potentially Detrimental Effects of Hyperosmolality in Patients Treated for Traumatic Brain Injury

2021

Hyperosmotic therapy is commonly used to treat intracranial hypertension in traumatic brain injury patients. Unfortunately, hyperosmolality also affects other organs. An increase in plasma osmolality may impair kidney, cardiac, and immune function, and increase blood–brain barrier permeability. These effects are related not only to the type of hyperosmotic agents, but also to the level of hyperosmolality. The commonly recommended osmolality of 320 mOsm/kg H2O seems to be the maximum level, although an increase in plasma osmolality above 310 mOsm/kg H2O may already induce cardiac and immune system disorders. The present review focuses on the adverse effects of hyperosmolality on the function…

medicine.medical_specialtyKidneyOsmotic concentrationTraumatic brain injurybusiness.industryosmolar gapmannitolRGeneral MedicineReviewmedicine.diseaseHypertonic salinePlasma osmolalitymedicine.anatomical_structureEndocrinologyImmune systemInternal medicineRenal physiologymedicineMedicineAdverse effectbusinessosmolalitytraumatic brain injury (TBI)hypertonic salineJournal of Clinical Medicine
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