0000000000481822

AUTHOR

Ejaz Ahmed Khan

showing 6 related works from this author

International Multicentre Study of Candida auris Infections

2021

Background:Candida auris has emerged globally as a multi-drug resistant yeast and is commonly associated with nosocomial outbreaks in ICUs. Methods: We conducted a retrospective observational multicentre study to determine the epidemiology of C. auris infections, its management strategies, patient outcomes, and infection prevention and control practices across 10 centres from five countries. Results: Significant risk factors for C. auris infection include the age group of 61–70 years (39%), recent history of ICU admission (63%), diabetes (63%), renal failure (52%), presence of CVC (91%) and previous history of antibiotic treatment (96%). C. auris was commonly isolated from blood (76%). Echi…

Microbiology (medical)Settore MED/07 - Microbiologia E Microbiologia Clinicamedicine.medical_specialtyEchinocandinC. auris Candida Fungi Nosocomial Outbreak ResistanceQH301-705.5Plant ScienceEmergenceresistancechemistry.chemical_compound<i>C. auris</i>Internal medicine<p>C. auris</p>EpidemiologymedicineInfection controlBiology (General)Ecology Evolution Behavior and SystematicsCandidaoutbreakbusiness.industryMortality rateMicafunginnosocomialResistantManagement<i>Candida</i>chemistryCandida aurisAnidulafunginfungiCaspofunginbusinessmedicine.drug
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The burden and epidemiology of community-acquired central nervous system infections: a multinational study

2017

Ghaydaa, Shehata/0000-0002-3631-893X; Radic, Ljiljana Betica/0000-0002-8778-106X; Silva-Pinto, Andre/0000-0002-2077-3356; Cascio, Antonio/0000-0002-1992-1796; Bossi, Paolo/0000-0003-0135-0224; Stebel, Roman/0000-0001-6922-4465; Namani, Sadie/0000-0002-2411-8623; Chan, Phillip/0000-0002-4071-4409; Hargreaves, Sally/0000-0003-2974-4348; Artuk, Cumhur/0000-0003-0827-990X; Harxhi, Arjan/0000-0001-8518-7377; Larsen, Lykke/0000-0002-4113-4182; Uysal, Serhat/0000-0002-4294-5999 WOS: 000407582200010 PubMed: 28397100 Risk assessment of central nervous system (CNS) infection patients is of key importance in predicting likely pathogens. However, data are lacking on the epidemiology globally. We perfor…

0301 basic medicineMaleOutcome AssessmentAdverse Clinical Outcomemedicine.disease_causeCentral nervous system infections ; burden ; epidemiologyMedical microbiologyCentral Nervous System InfectionsOutcome Assessment Health CareEpidemiology80 and overAged 80 and overbiologyAge FactorsGeneral MedicineMiddle AgedCommunity-Acquired InfectionsInfectious Diseases[SDV.MP]Life Sciences [q-bio]/Microbiology and ParasitologyPopulation SurveillanceFemaleNeuroborreliosisHuman Immunodeficiency VirusMicrobiology (medical)Adultmedicine.medical_specialtyTuberculosisSettore MED/17 - Malattie Infettive030106 microbiologyBrain AbscessCentral Nervous System InfectionNeurosyphilisMycobacterium tuberculosis03 medical and health sciencesYoung AdultInternal medicineStreptococcus pneumoniaeJournal ArticlemedicineHumansAgedRetrospective Studiesbusiness.industryVaricella zoster virusmedicine.diseasebiology.organism_classificationHealth CareCross-Sectional StudiesCentral Nervous System DiseaseBrain AbsceHuman Immunodeficiency ViruImmunologybusiness
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Portraying infective endocarditis

2019

Infective endocarditis is a growing problem with many shifts due to ever-increasing comorbid illnesses, invasive procedures, and increase in the elderly. We performed this multinational study to depict definite infective endocarditis. Adult patients with definite endocarditis hospitalized between January 1, 2015, and October 1, 2018, were included from 41 hospitals in 13 countries. We included microbiological features, types and severity of the disease, complications, but excluded therapeutic parameters. A total of 867 patients were included. A total of 631 (72.8%) patients had native valve endocarditis (NVE), 214 (24.7%) patients had prosthetic valve endocarditis (PVE), 21 (2.4%) patients …

MaleInternationalityAucunInfective endocarditimedicine.disease_causeMedical microbiology80 and overBlood cultureHospital MortalityAged 80 and overmedicine.diagnostic_testbiologyEndocarditisSBacterialGeneral MedicineSciences bio-médicales et agricolesMiddle AgedStaphylococcal InfectionsSciences du Vivant [q-bio]/Microbiologie et ParasitologieViridans StreptococciCatheterInfectious Diseases[SDV.MP]Life Sciences [q-bio]/Microbiology and ParasitologyStaphylococcus aureusInfective endocarditisAortic ValveMitral ValveFemaleMicrobiology (medical)Adultmedicine.medical_specialtyProsthesis-Related InfectionsAdolescentaureusBlood cultureYoung AdultInternal medicinemedicineEndocarditisHumansresults of multinational ID-IRI study- EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES cilt.38 ss.1753-1763 2019 [Erdem H. Puca E. Ruch Y. Santos L. Ghanem-Zoubi N. Argemi X. Hansmann Y. Guner R. Tonziello G. Mazzucotelli J. et al. -Portraying infective endocarditis]ProstheticAgedNative Valve EndocarditisBacteriabusiness.industryEndocarditis Bacterialmedicine.diseasebiology.organism_classificationS. aureusViridans streptococciInfective endocarditisbusinessNative
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Self-reported antibiotic stewardship and infection control measures from 57 intensive care units: An international ID-IRI survey

2022

Infection control; Multidrug resistance; Stewardship Control de infección; Resistencia a múltiples fármacos; Administración Control d'infecció; Resistència a múltiples fàrmacs; Administració We explored the self-reported antibiotic stewardship (AS), and infection prevention and control (IPC) activities in intensive care units (ICUs) of different income settings. A cross-sectional study was conducted using an online questionnaire to collect data about IPC and AS measures in participating ICUs. The study participants were Infectious Diseases–International Research Initiative (IDI-IR) members, committed as per their institutional agreement form. We analyzed responses from 57 ICUs in 24 countri…

:Investigative Techniques::Epidemiologic Methods::Data Collection::Surveys and Questionnaires [ANALYTICAL DIAGNOSTIC AND THERAPEUTIC TECHNIQUES AND EQUIPMENT]EpidemiologyIntensive Care UnitInfection controlAmerica:acciones y usos químicos::acciones farmacológicas::usos terapéuticos::antiinfecciosos::antibacterianos [COMPUESTOS QUÍMICOS Y DROGAS]Multidrug resistanceCommunicable DiseasesEnquestesPan drug resistanceCommunicable DiseaseAntimicrobial StewardshipSurveys and QuestionnairesAnti-Bacterial AgentHumansMedicaments antibacterians - Ús terapèuticStewardshipSurveys and QuestionnaireSocietyUnitats de cures intensivesCross-Sectional StudieInfection ControlCross InfectionPreventionPublic Health Environmental and Occupational Health:técnicas de investigación::métodos epidemiológicos::recopilación de datos::encuestas y cuestionarios [TÉCNICAS Y EQUIPOS ANALÍTICOS DIAGNÓSTICOS Y TERAPÉUTICOS]General MedicineMDROAnti-Bacterial AgentsIntensive Care Units:Health Care Facilities Manpower and Services::Health Facilities::Hospital Units::Intensive Care Units [HEALTH CARE]Cross-Sectional StudiesInfectious Diseases:instalaciones servicios y personal de asistencia sanitaria::centros sanitarios::unidades hospitalarias::unidades de cuidados intensivos [ATENCIÓN DE SALUD]:Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Anti-Infective Agents::Anti-Bacterial Agents [CHEMICALS AND DRUGS]Self ReportMDROsLow- and upper-middle and high incomeHuman
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Profiles of multidrug-resistant organisms among patients with bacteremia in intensive care units: an international ID-IRI survey

2021

Evaluating trends in antibiotic resistance is a requisite. The study aimed to analyze the profile of multidrug-resistant organisms (MDROs) among hospitalized patients with bacteremia in intensive care units (ICUs) in a large geographical area. This is a 1-month cross-sectional survey for blood-borne pathogens in 57 ICUs from 24 countries with different income levels: lower-middle-income (LMI), upper-middle-income (UMI), and high-income (HI) countries. Multidrug-resistant (MDR), extensively drug-resistant (XDR), or pan-drug-resistant isolates were searched. Logistic regression analysis determined resistance predictors among MDROs. Community-acquired infections were comparable to hospital-acq…

Male0301 basic medicineKlebsiella pneumoniaeDrug ResistanceInfection controlMultidrug resistance0302 clinical medicineMedical microbiologyDrug Resistance Multiple Bacterial80 and overInfection controlMedicine030212 general & internal medicineChildAged 80 and overCross InfectionbiologyMicrobial Sensitivity TestBacterialBacterial InfectionsGeneral MedicineMiddle AgedSciences bio-médicales et agricolesCountriesAnti-Bacterial AgentsAcinetobacter baumanniiEuropeIntensive Care UnitsInfectious DiseasesChild PreschoolFemaleMultipleMicrobiology (medical)Adultmedicine.medical_specialtyAdolescent030106 microbiologyIntensive Care UnitPan-drug resistanceMicrobial Sensitivity TestsInfectionsBacterial InfectionYoung Adult03 medical and health sciencesAntibiotic resistanceIntensive careInternal medicineAnti-Bacterial AgentHumansStewardshipXDRPreschoolAgedCross-Sectional StudieBacteriabusiness.industryInfantbiology.organism_classificationmedicine.diseaseMultiple drug resistanceCross-Sectional StudiesBacteremiabusinessLow- and upper-middle and high income
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Vector-borne and zoonotic infections and their relationships with regional and socioeconomic statuses: An ID-IRI survey in 24 countries of Europe, Af…

2021

Background: In this cross-sectional, international study, we aimed to analyze vector-borne and zoonotic infections (VBZI), which are significant global threats. Method: VBZIs’ data between May 20–28, 2018 was collected. The 24 Participatingcountries were classified as lower-middle, upper-middle, and high-income. Results: 382 patients were included. 175(45.8%) were hospitalized, most commonly in Croatia, Egypt, and Romania(P = 0.001). There was a significant difference between distributions of VBZIs according to geographical regions(P &lt; 0.001). Amebiasis, Ancylostomiasis, Blastocystosis, Cryptosporidiosis, Giardiasis, Toxoplasmosis were significantly more common in the Middle-East while B…

AsiaSurveillance data030231 tropical medicineeducationEconomic statuTickSocioeconomic FactorZoonosis03 medical and health sciences0302 clinical medicineEconomic statusZoonosiMultidisciplinary approachZoonosesEnvironmental healthmedicineAnimalsHumansHemorrhagic Fever Crimean ...economic status ; infection ; tick ; vector ; zoonosisSocioeconomic statushealth care economics and organizationsCross-Sectional Studie0303 health sciencesZoonotic InfectionbiologyAnimal030306 microbiologyZoonosisSignificant differencePublic Health Environmental and Occupational HealthAn ID-IRI survey in 24 countries of Europe Africa and Asia- TRAVEL MEDICINE AND INFECTIOUS DISEASE cilt.44 2021 [Saydam F. N. Erdem H. ANKARALI H. Ramadan M. E. E. El-Sayed N. M. Civljak R. Pshenichnaya N. Moroti R. V. Mahmuodabad F. M. Maduka A. V. et al. -Vector-borne and zoonotic infections and their relationships with regional and socioeconomic statuses]medicine.diseasebiology.organism_classification3. Good healthEuropeCross-Sectional StudiesInfectious DiseasesGeographySocioeconomic FactorsVector (epidemiology)AfricaHemorrhagic Fever Virus Crimean-CongoHemorrhagic Fever CrimeanVectorInfectionTick
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