0000000000512735

AUTHOR

Irene Galiana

showing 3 related works from this author

Enhanced antifungal efficacy of tebuconazole using gated pH-driven mesoporous nanoparticles

2014

Núria Mas,1–3 Irene Galiana,3 Silvia Hurtado,† Laura Mondragón,1–3 Andrea Bernardos,1–3 Félix Sancenón,1–3 María D Marcos,1–3 Pedro Amorós,4 Nuria Abril-Utrillas,5 Ramón Martínez-Máñez,1–3 José Ramón Murguía1,3 1Centro de Reconocimiento Molecular y Desarrollo Tecnológico (IDM), Centro Mixto Universidad Politécnica de Valencia, Universidad de Valencia, Valencia, Spain; 2Departamento de Química, Universidad Politécnica de Valencia, Valenci…

INGENIERIA DE LA CONSTRUCCIONMaterials scienceAntifungal AgentsPH-responsive nanoparticlesCell Survivalmedia_common.quotation_subjectCapped mesoporous nanoparticlesBiophysicsPharmaceutical ScienceNanoparticleBioengineeringSaccharomyces cerevisiaeNanocapsulesBiomaterialsDiffusionchemistry.chemical_compoundNanoporesQUIMICA ORGANICANanocapsulesInternational Journal of NanomedicineDrug DiscoveryQUIMICA ANALITICABIOQUIMICA Y BIOLOGIA MOLECULARFluoresceinParticle SizeCytotoxicityInternalizationmedia_commonTebuconazoleOriginal ResearchIntracellular releaseOrganic ChemistryQUIMICA INORGANICADrug SynergismGeneral MedicineMesoporous silicaHydrogen-Ion ConcentrationTriazoleschemistryBiochemistryDelayed-Action PreparationsBiophysicsTebuconazole loadingMesoporous materialPorosityInternational Journal of Nanomedicine
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Poly(N-isopropylacrylamide)-gated Fe3O4/SiO2 core shell nanoparticles with expanded mesoporous structures for the temperature triggered release of ly…

2015

Core-shell nanoparticles comprised of Fe3O4 cores and a mesoporous silica shell with an average expanded pore size of 6.07 nm and coated with a poly(N-isopropylacrylamide) (PNIPAM) layer (CS MSNs EP PNIPAM) were prepared and characterized. The nanoparticles was loaded with (Ru(bipy)3 2+) dye or an antibacterial enzyme, lysozyme, to obtain CS MSNs EP PNIPAM Ru(bipy)3 2+ and CS MSNs EP PNIPAM Lys, respectively. The lysozyme loading was determined to be 160 mg/g of nanoparticle. It was seen that Ru(bipy)3 2+ and lysozyme release was minimal at a room temperature of 25 ºC while at physiological temperature (37 º C), abrupt release was observed. The applicability of the CS MSNs EP PNIPAM Lys was…

INGENIERIA DE LA CONSTRUCCIONSilicon dioxideAcrylic ResinsBiomedical EngineeringNanoparticleBioengineeringchemistry.chemical_compoundPNIPAMQUIMICA ORGANICAColloid and Surface ChemistryBacillus cereusBIOQUIMICA Y BIOLOGIA MOLECULARNanotechnologyFerrous CompoundsPhysical and Theoretical ChemistryChemical PhysicsChromatographybiologyProtein deliveryQUIMICA INORGANICATemperatureTriggered releaseSurfaces and InterfacesGeneral MedicineChemical EngineeringMesoporous silicaSilicon Dioxidebiology.organism_classificationAnti-Bacterial AgentsMicrococcus luteuschemistryDrug deliveryPoly(N-isopropylacrylamide)NanoparticlesMuramidaseLysozymePore expansionMesoporous materialMicrococcus luteusPorosityMesoporous silicaPhysical Chemistry (incl. Structural)BiotechnologyNuclear chemistryColloids and Surfaces B: Biointerfaces
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Enhanced Efficacy and Broadening of Antibacterial Action of Drugs via the Use of Capped Mesoporous Nanoparticles

2013

[EN] A novel nanodevice consisting of mesoporous nanoparticles loaded with vancomycin and capped with epsilon-poly-L-lysine (epsilon-PL) was prepared and its interaction with different Gram-negative bacteria studied. A remarkable improvement in the efficacy of the antimicrobial drug epsilon-PL and a broadening of the antimicrobial spectrum of vancomycin is demonstrated.

INGENIERIA DE LA CONSTRUCCIONNanoparticleNanotechnologyMicrobial Sensitivity TestsCatalysisQUIMICA ORGANICAVancomycinGram-Negative BacteriaQUIMICA ANALITICABIOQUIMICA Y BIOLOGIA MOLECULARmedicinePolylysineGated materialsNanodeviceDrug CarriersChemistryQUIMICA INORGANICAOrganic ChemistryGeneral ChemistrySilicon DioxideAntimicrobialMesoporous materialsAnti-Bacterial AgentsAntimicrobial drugepsilon-poly-L-lysineNanoparticlesVancomycinAntibacterial actionMesoporous materialPorositymedicine.drugChemistry - A European Journal
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