0000000000660350

AUTHOR

Mauricio

showing 4 related works from this author

Anti-adrenergic effects of ranolazine in isolated rat aorta

2014

Ranolazine, a piperazine derivative, is used as an anti- anginal drug to treat patients with chronic angina in clinical practice [1] and may improve coronary blood flow by reducing compression effects of ischemic contracture, and by improving endothelial function [2],[3]. In the present study we investigate the vascular effects of ranolazine on the endothelium, adrenergic system and Ca2+ in isolated rat aorta.

DrugAortaEndotheliumbusiness.industrymedia_common.quotation_subjectRanolazineAdrenergicChronic anginaBlood flowIschemic ContracturePharmacologyCritical Care and Intensive Care Medicinemedicine.anatomical_structuremedicine.arteryPoster Presentationmedicinebusinessmedicine.drugmedia_commonCritical Care
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Effects of exercise training on adrenergic and cholinergic responses of rabbit carotid artery

2013

medicine.medical_specialtyAdrenergic receptorbusiness.industryAdrenergicNorepinephrine (medication)EndocrinologyInternal medicinemedicine.arteryPrazosinMedicineCholinergicCommon carotid arteryCardiology and Cardiovascular MedicinebusinessAcetylcholineGuanethidinemedicine.drugEuropean Heart Journal
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Anti-inflammatory and antioxidant effects of ranolazine on primary cultured astrocytes

2014

Because of its ability to block late INa [1], ranolazine is used as an antianginal agent for the treatment of chronic angina pectoris when angina is not adequately controlled by other agents [2]. Besides its cardiovascular effects, ranolazine improves different neuronal functions, and thus its use has been proposed for the treatment of pain and epileptic disorders [3,4]. Since astrocytes are involved in neuronal inflammatory processes, and autoimmune and neurodegenerative diseases [5], we have investigated the antiinflammatory and antioxidant effects of ranolazine in primary cultured astrocytes.

Antioxidantmedicine.drug_classbusiness.industrymedicine.medical_treatmentRanolazineChronic anginaPharmacologymedicine.diseaseCritical Care and Intensive Care MedicineAnti-inflammatoryAnginaPoster Presentationmedicinebusinessmedicine.drugCritical Care
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Unchanged plasma levels of dimethylarginines and nitric oxide in chronic hepatitis C.

2008

Previous studies have shown that asymmetric dimethylarginine (ADMA), symmetric dimethylarginine (SDMA) and nitric oxide (NO) play a prominent role in liver dysfunction. The objective of this study was to determine whether plasma levels of ADMA, SDMA and NO are altered in patients with chronic hepatitis C.Plasma levels of ADMA, SDMA and NO (nitrite plus nitrate) were measured in 22 patients with chronic hepatitis C and 24 patients with sustained virologic response after treatment with peginterferon plus ribavirin. Seven healthy volunteers served as controls.Plasma levels of ADMA, SDMA and NO were not significantly different between groups: chronic hepatitis C, ADMA 0.55+/-0.06, SDMA 0.22+/-0…

AdultMalemedicine.medical_specialtyArginineInterferon alpha-2ArginineNitric OxideAntiviral AgentsNitric oxidePolyethylene Glycolschemistry.chemical_compoundInterferonInternal medicineBlood plasmaRibavirinMedicineHumansbusiness.industryRibavirinGastroenterologyCase-control studyInterferon-alphaHepatitis CHepatitis C ChronicMiddle Agedmedicine.diseaseRecombinant ProteinsEndocrinologychemistryCase-Control StudiesFemalebusinessAsymmetric dimethylargininemedicine.drugScandinavian journal of gastroenterology
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