Anti-adrenergic effects of ranolazine in isolated rat aorta

6533b82afe1ef96bd128b7b2

RESEARCH PRODUCT

Anti-adrenergic effects of ranolazine in isolated rat aorta

Mauricio Martin Aldasoro Diana Aguirre-rueda Fb El Amrani Soraya L. Valles S Guerra Jose Mª Vila Patricia Marchio

subject

Drug Aorta Endothelium business.industry media_common.quotation_subject Ranolazine Adrenergic Chronic angina Blood flow Ischemic Contracture Pharmacology Critical Care and Intensive Care Medicine medicine.anatomical_structure medicine.artery Poster Presentation medicine business medicine.drug media_common

description

Ranolazine, a piperazine derivative, is used as an anti- anginal drug to treat patients with chronic angina in clinical practice [1] and may improve coronary blood flow by reducing compression effects of ischemic contracture, and by improving endothelial function [2],[3]. In the present study we investigate the vascular effects of ranolazine on the endothelium, adrenergic system and Ca2+ in isolated rat aorta.

year	journal	country	edition	language
2014-03-01	Critical Care

10.1186/cc13374 http://europepmc.org/articles/PMC4068193

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