0000000001112323

AUTHOR

Nicolas Probst

showing 2 related works from this author

Cooperative Assistance in Bifunctional Organocatalysis: Enantioselective Mannich Reactions with Aliphatic and Aromatic Imines

2012

both of which contain a thiourea moiety (Scheme 1).The catalysts are capable of deprotonating suitable nucleo-philes, such as activated carbonyl compounds. This proton-transfer reaction generates an ion pair, which is composed ofthe protonated catalyst and the anionic nucleophile interact-ing through hydrogen bonds. At least one of the NH moietiesin the protonated catalyst is involved in activating theelectrophilic reaction partner.

Models MolecularHydrogen bond catalysisImineEnantioselective synthesisHydrogen BondingStereoisomerismGeneral MedicineGeneral ChemistryCrystallography X-RayMalonatesCatalysisCatalysischemistry.chemical_compoundchemistryNucleophileOrganocatalysisPolymer chemistryOrganic chemistryMoietyIminesAmino AcidsBifunctionalta116Angewandte Chemie International Edition
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ChemInform Abstract: Cooperative Assistance in Bifunctional Organocatalysis: Enantioselective Mannich Reactions with Aliphatic and Aromatic Imines.

2013

both of which contain a thiourea moiety (Scheme 1).The catalysts are capable of deprotonating suitable nucleo-philes, such as activated carbonyl compounds. This proton-transfer reaction generates an ion pair, which is composed ofthe protonated catalyst and the anionic nucleophile interact-ing through hydrogen bonds. At least one of the NH moietiesin the protonated catalyst is involved in activating theelectrophilic reaction partner.

chemistry.chemical_compoundNucleophileThioureachemistryHydrogen bondOrganocatalysisEnantioselective synthesisMoietyGeneral MedicineBifunctionalCombinatorial chemistryCatalysisChemInform
researchProduct