0000000001308405
AUTHOR
Marina Petrova
ChemInform Abstract: Synthesis and Self-Assembly of Novel Fluorous Cationic Amphiphiles with a 3,4-Dihydro-2(1H)-pyridone Spacer.
Abstract The synthesis of fluorous (highly fluorinated) 3,4-dihydro-2(1 H )-pyridone-5-carboxylate cationic amphiphiles have been described, where the dihydropyridone serves as a spacer and either a pyridinium bromide or a triphenylphosphonium bromide form the polar cationic head group. The in water self-assembled aggregates have been observed by atomic force microscopy (AFM) and dynamic light scattering (DLS).
Synthesis and self-assembly of novel fluorous cationic amphiphiles with a 3,4-dihydro-2(1H)-pyridone spacer
Abstract The synthesis of fluorous (highly fluorinated) 3,4-dihydro-2(1 H )-pyridone-5-carboxylate cationic amphiphiles have been described, where the dihydropyridone serves as a spacer and either a pyridinium bromide or a triphenylphosphonium bromide form the polar cationic head group. The in water self-assembled aggregates have been observed by atomic force microscopy (AFM) and dynamic light scattering (DLS).
Weaning from mechanical ventilation in intensive care units across 50 countries (WEAN SAFE)
Background: Current management practices and outcomes in weaning from invasive mechanical ventilation are poorly understood. We aimed to describe the epidemiology, management, timings, risk for failure, and outcomes of weaning in patients requiring at least 2 days of invasive mechanical ventilation. Methods: WEAN SAFE was an international, multicentre, prospective, observational cohort study done in 481 intensive care units in 50 countries. Eligible participants were older than 16 years, admitted to a participating intensive care unit, and receiving mechanical ventilation for 2 calendar days or longer. We defined weaning initiation as the first attempt to separate a patient from the ventila…
Stereoselective synthesis and properties of 1,3-bis(dicyanomethylidene)indane-5-carboxylic acid acceptor fragment containing nonlinear optical chromophores
A series of organic push–pull type chromophores using indane-1,3-dione 5-carboxylic acid (IDCA) and novel 1,3-bis(dicyanomethylidene)indane 5-carboxylic acid (CICA) electron acceptor fragments have been synthesized and characterized. NMR and X-ray analysis revealed that condensation reactions with the CICA fragment were stereoselective and yielded benzylidenes and azomethines with E double bond configurations. Due to the non-planar geometry these compounds are chiral and were acquired as a racemic mixture. The subsequent functionalization of the carboxylic acid group with 5,5,5-triphenylpentan-1-ol yielded solution-processable glass forming materials (6, 8, 10, 13) with glass transition tem…
Synthesis, physicochemical characterization, cytotoxicity, antimicrobial, anti-inflammatory and psychotropic activity of new N-[1,3-(benzo)thiazol-2-yl]-ω-[3,4-dihydroisoquinolin-2(1H)-yl]alkanamides.
Abstract A series of new N-[(benzo)thiazol-2-yl]-2/3-[3,4-dihydroisoquinolin-2(1H)-yl]ethan/propanamide derivatives was synthesized and characterized by 1H, 13C NMR and IR spectroscopy and mass-spectrometry. A single crystal X-ray study of N-(1,3-benzothiazol-2-yl)-2-[3,4-dihydroisoquinolin-2(1H)-yl]ethanamide is reported to determine its conformational feature. The investigated compounds were found to be active in psychotropic in vivo, anti-inflammatory in vivo and cytotoxicity in vitro screening. They possess marked sedative action, reveal high anti-inflammatory activity, have selective cytotoxic effects and NO-induction ability concerning tumour cell lines. Some of the compounds synthesi…
Uzvedības kultūras veidošanās četru līdz piecu gadu veciem bērniem pirmsskolas izglītības iestādē
3 ANOTĀCIJA Darba autors: Marina Petrova Darba tēma: Uzvedības kultūras veidošanās četru līdz piecu gadu veciem bērniem pirmsskolas izglītības iestādē Darba veids: diplomdarbs Darba zinātniskais vadītājs: Iveta Ėestere, vad. pētniece Darba apjoms: 37 lpp. Pētījuma mērėis: Balstoties uz teorētiskām atziĦām un empīriskiem pētījumiem, izveidot nodarbību plānu uzvedības kultūras veidošanās veicināšanai pirmsskolas vecuma bērniem. Darba saturs: diplomdarbs izstrādāts, lai veicinātu uzvedības kultūras veidošanos pirmsskolas vecuma bērniem. Tam ir trīs daĜas: 1. Teorētiskās nostādnes, kas atklāj kultūras veicinošo lomu pirmsskolas vecuma bērnu attīstībā. 2. Pirmsskolas vecuma bērniem adresēto kult…
CCDC 907303: Experimental Crystal Structure Determination
Related Article: Alla Zablotskaya, Izolda Segal, Athina Geronikaki, Tatiana Eremkina, Sergey Belyakov, Marina Petrova, Irina Shestakova, Liga Zvejniece, Vizma Nikolajeva|2013|Eur.J.Med.Chem.|70|846|doi:10.1016/j.ejmech.2013.10.008
CCDC 1436954: Experimental Crystal Structure Determination
Related Article: Kaspars Traskovskis, Valdis Kokars, Andrejs Tokmakovs, Igors Mihailovs, Edgars Nitiss, Marina Petrova, Sergey Belyakov, Martins Rutkis|2016|J.Mater.Chem.C|4|5019|doi:10.1039/C6TC00203J