0000000001322908
AUTHOR
Jens Emsermann
Photochemical Approaches to the Bilobalide Core
Bilobalide is a tetracyclic sesquiterpene containing three contiguous γ-lactone rings and an unusual tert-butyl group, which is found in the leaves of the ginkgo tree (Ginkgo biloba). Three different photochemical approaches towards bilobalide's unique skeleton are presented. A meta photocycloaddition, a [2 + 2] photocycloaddition, and a Paterno–Buchi-reaction were chosen as the respective key steps.
Marine Isonitriles and Their Related Compounds.
Marine isonitriles represent the largest group of natural products carrying the remarkable isocyanide moiety. Together with marine isothiocyanates and formamides, which originate from the same biosynthetic pathways, they offer diverse biological activities and in spite of their exotic nature they may constitute potential lead structures for pharmaceutical development. Among other biological activities, several marine isonitriles show antimalarial, antitubercular, antifouling and antiplasmodial effects. In contrast to terrestrial isonitriles, which are mostly derived from α-amino acids, the vast majority of marine representatives are of terpenoid origin. An overview of all known marine isoni…
Synthesis of Highly Substituted 2-13C-Imidazolium Salts and Metal NHC Complexes for the Investigation of Electronic Unsymmetry by NMR
Complexes of unsymmetrically substituted N-heterocyclic carbenes with NMR-active metals (Ag, Hg, Pt) with or without a 13C-label in the 2-position were synthesized by aldimine cross coupling and analyzed with respect to the scalar couplings between the metal center or C2 and the other ring atoms.
CCDC 1541882: Experimental Crystal Structure Determination
Related Article: Jens Emsermann, Till Opatz|2017|Eur.J.Org.Chem.|2017|3362|doi:10.1002/ejoc.201700461