6533b7d0fe1ef96bd125af66
RESEARCH PRODUCT
Percutaneous antegrade electropapillotomy. Study in dogs.
S. StörkelR. W. GüntherK. J. Klosesubject
Malemedicine.medical_specialtyAmpulla of VaterPercutaneousDuodenumElectrosurgeryCholangiographyDogsPressureMedicineAnimalsRadiology Nuclear Medicine and imagingAspartate AminotransferasesCommon Bile DuctCommon bile ductmedicine.diagnostic_testbusiness.industryHepatobiliary diseaseAlanine Transaminasemedicine.diseaseAlkaline PhosphataseSurgeryMajor duodenal papillaRadiographymedicine.anatomical_structureAmylasesDuodenumSphincterFemalePapillary stenosisCardiology and Cardiovascular Medicinebusinessdescription
Antegrade electropapillotomy using the percutaneous transcystic approach was successfully performed in 11 of 16 dogs. When the intervention was effective, the pressure gradient between common bile duct and duodenum decreased from 6 to 1.3 mm Hg on average and returned to gradients slightly below the initial values after 4 weeks, owing to reactivation of the sphincter mechanism. Ineffective cutting, however, resulted in a temporary pressure rise. In one dog a papillary stenosis developed and was relieved by antegrade electrocutting. Irrespective of the success of the papillotomy, rises in levels of serum glutamine oxaloacetic and pyruvic transaminase, alkaline phosphatase, serum amylase and leukocytes were seen. Although the method is technically feasible, its clinical significance is not so much for antegrade papillotomy but rather for transhepatic incision of stenoses after hepaticojejunostomy.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1984-12-01 | Cardiovascular and interventional radiology |