6533b7d1fe1ef96bd125c2ff
RESEARCH PRODUCT
The comparison of beta-thymosin homologues among metazoa supports an arthropod-nematode clade.
Michaël ManuelWerner E.g. MüllerYannick Le ParcoMichael Krusesubject
biologyNematodaSequence Homology Amino AcidPhylumMolecular Sequence DataZoologybiology.organism_classificationCladisticsThymosinMonophylyNematodeDrosophila melanogasterPhylogeneticsGeneticsAnimalsArthropodAmino Acid SequenceCladeCaenorhabditis elegansMolecular BiologyEcdysozoaArthropodshormones hormone substitutes and hormone antagonistsEcology Evolution Behavior and SystematicsPhylogenydescription
The definition of an Ecdysozoa clade among the protostomians, including all phyla with a regularly molted alpha-chitin-rich cuticle, has been one of the most provocative hypotheses to arise from recent investigations on animal phylogeny. Here we present evidence in favor of an arthropod-nematode clade, from the comparison of beta-thymosin homologues among the Metazoa. Arthropods and nematodes share the absence of the highly conserved beta-thymosin form found in all other documented bilaterian phyla as well as sponges, and the possession of a very unusual, internally triplicated homologue of the beta-thymosin protein, unknown in other phyla. We argue that such discrete molecular character is phylogenetically very powerful and provides strong evidence for the monophyly of an arthropod-nematode clade.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2000-10-01 | Journal of molecular evolution |