6533b7d2fe1ef96bd125ed0d
RESEARCH PRODUCT
Echocardiographic reference ranges for normal left ventricular 2D strain: results from the EACVI NORRE study
Ralph Stephan Von BardelebenJosé Luis ZamoranoJose David Rodrigo CarboneroMaurizio GalderisiDaniele BaroneMonica BaroniErwan DonalGonzalo De La MorenaKrasimira HristovaFederica IlardiTolga OzyigitLaura ContuAnne BernardAnne BernardNatela AkhaladzeMartin PenickaYun Yun GoNico Van De VeireKarima AddetiaStella MarchettaBernard CosynsNuno CardimLuis CaballeroJulien MagneRoberto M. LangDragos VinereanuRaluca Elena DulgheruLuigi P. BadanoPatrizio LancellottiAndreas HagendorffAndrea CalinTadafumi SugimotoMonica RoscaGilbert HabibGeorge AthanassopoulosBogdan A. PopescuMarie MoonenTeresa Lópezsubject
MaleLongitudinal straindeformation imaging[SDV]Life Sciences [q-bio]Sex Factor030204 cardiovascular system & hematologyStandard deviationVentricular Function LeftHeart Ventricle2D echocardiography0302 clinical medicineReference ValuesNuclear Medicine and ImagingImage Processing Computer-AssistedMedicineCircumferential strainAge FactorReference Value030212 general & internal medicineMultivariate Analysi2D echocardiography; Adult echocardiography; Deformation imaging; Reference values; Radiology Nuclear Medicine and Imaging; Cardiology and Cardiovascular MedicineObserver VariationStrain (chemistry)Age FactorsGeneral MedicineMiddle AgedHealthy VolunteerHealthy VolunteersEuropeHomogeneousEchocardiographyRadiology Nuclear Medicine and imagingCardiologyLinear ModelFemaleRadiologyCardiology and Cardiovascular MedicineRadial stressHumanAdultmedicine.medical_specialtyadult echocardiographyHeart Ventricles03 medical and health sciencesSex FactorsInternal medicineHumansRadiology Nuclear Medicine and imaging2d strainbusiness.industryMED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLAREReference valuesMultivariate AnalysisLinear Modelsbusinessdescription
International audience; Aims - To obtain the normal ranges for 2D echocardiographic (2DE) measurements of left ventricular (LV) strain from a large group of healthy volunteers accounting for age and gender. Methods and results - A total of 549 (mean age: 45.6 ± 13.3 years) healthy subjects were enrolled at 22 collaborating institutions of the Normal Reference Ranges for Echocardiography (NORRE) study. 2DE data sets have been analysed with a vendor-independent software package allowing homogeneous measurements irrespective of the echocardiographic equipment used to acquire the data sets. The lowest expected values of LV strains and twist calculated as ± 1.96 standard deviations from the mean were -16.7% in men and -17.8% in women for longitudinal strain, -22.3% and -23.6% for circumferential strain, 20.6% and 21.5% for radial strain, and 2.2 degrees and 1.9 degrees for twist, respectively. In multivariable analysis, longitudinal strain decreased with age whereas the opposite occurred with circumferential and radial strain. Male gender was associated with lower strain for longitudinal, circumferential, and radial strain. Inter-vendor differences were observed for circumferential and radial strain despite the use of vendor-independent software. Importantly, no intervendor differences were noted in longitudinal strain. Conclusion - The NORRE study provides contemporary, applicable 2D echocardiographic reference ranges for LV longitudinal, radial, and circumferential strain. Our data highlight the importance of age- and gender-specific reference values for LV strain.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2017-08-01 |