6533b7d3fe1ef96bd1261624

RESEARCH PRODUCT

Efficacy and Safety of a Preemptive Antiviral Therapy Strategy Based on Combined Virological and Immunological Monitoring for Active Cytomegalovirus Infection in Allogeneic Stem Cell Transplant Recipients.

Monserrat RoviraJavier LópezJose B NietoLourdes VázquezPaula AmatJosé Luis PiñanaCarlos SolanoDavid NavarroDavid P. SerranoEstela GiménezRafael De La Cámara

subject

0301 basic medicineCongenital cytomegalovirus infectionViremiaContext (language use)DiseaseMajor Articles03 medical and health sciences0302 clinical medicineInterferonImmunityallogeneic stem cell transplantationimmunological monitoringMedicineIFN-γ CD8+ T cellscytomegalovirusbusiness.industryvirus diseasesmedicine.disease030104 developmental biologyInfectious DiseasesOncologypreemptive antiviral therapyImmunologyStem cellbusinessCD8030215 immunologymedicine.drug

description

Preemptive antiviral therapy for active CMV infection in allogeneic stem cell transplant recipients guided by immunological and virological parameters minimizes the risk of recurrent viremia in a subset of patients.

10.1093/ofid/ofw107https://pubmed.ncbi.nlm.nih.gov/27419179