6533b7d4fe1ef96bd1261db7

RESEARCH PRODUCT

Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation

Uwe K. ZettlMichael PützRajesh RawalFrauke ZippMartin StangelUlf SchminkeMarcus IsingMartina Müller-nurasyidHeinz WiendlJürgen HaasThomas MeitingerMichael HeckerWolfgang LiebMagdalena ZoledziewskaTania Carrillo-roaUlf ZiemannS. NischwitzStefan HermsStefan HermsMaristella PitzalisStefan KloiberFrank WeberFrank WeberHayrettin TumaniBertram Müller-myhsokBertram Müller-myhsokSven G. MeuthGeorg HomuthRalf GoldM. KnopAntonella MulasChristina M. LillChristina M. LillHenry VölzkeAntonios BayasFrancesco CuccaEleonora PorcuAndrew T. ChanAndrew T. ChanJanine ArlothLukas BechmannLukas BechmannDarina CzamaraDorothea BuckKlaus BergerPeter LichtnerJürgen WellmannSusanne MoebusAndre FrankeFlorian Then BerghPeter WeberThomas BetteckenIlenia ZaraTill F. M. AndlauerVolker LimmrothAchim BertheleRalf A. LinkerTobias RuckAnke SalmenAnke SalmenMatthias LaudesGisela AntonyChristiane GraetzChristian GiegerKonstantin StrauchAstrid PetersmannElisabeth B. BinderElisabeth B. BinderMelanie WaldenbergerChristiane GasperiCarlo SidoreBrigitte WildemannFriedemann PaulFelix LuessiBernhard HemmerKlarissa Hanja StürnerKarl-heinz JöckelMilena Radivojkov-blagojevicBjörn TackenbergTim KacprowskiLars BertramLars BertramClemens WarnkeMarkus O. ScheinhardtTheresa DankowskiVerena LoleitTania KümpfelCarmen Infante-duarteSusanne LucaeMarkus M. NöthenJan-patrick StellmannMark MühlauAndreas ZieglerAndreas Ziegler

subject

0301 basic medicineMaleDLEU1MedizinGenome-wide association studyEpigenesis GeneticCohort StudiesResearch ArticlesTranscriptional Regulator ERGGeneticsAged 80 and overGlycine Hydroxymethyltransferaseeducation.field_of_studyMultidisciplinaryDNA methylationSciAdv r-articlesMiddle AgedSHMT13. Good healthddc:DNA-Binding ProteinsERGDNA methylationFemaleMAZFunction and Dysfunction of the Nervous SystemResearch ArticleAdultAdolescentPopulationQuantitative Trait Loci610 Medicine & healthDleu1 ; Dna Methylation ; Erg ; L3mbtl3 ; Maz ; Multiple Sclerosis ; Shmt1 ; Genome-wide Association StudyQuantitative trait locusBiologyMajor histocompatibility complexNeurological DisordersMultiple sclerosis03 medical and health sciencesYoung AdultTranscriptional Regulator ERGHumansGenetic Predisposition to DiseaseL3MBTL3EpigeneticsAlleleeducationAllelesAgedgenome-wide association study030104 developmental biologyGenetic LociCase-Control Studiesbiology.proteinTranscription Factors

description

Genome-wide study in Germans identifies four novel multiple sclerosis risk genes and confirms already known gene loci.

yearjournalcountryeditionlanguage
2016-06-01
10.1126/sciadv.1501678http://hdl.handle.net/10044/1/39479