6533b7d4fe1ef96bd1262931

RESEARCH PRODUCT

First report on fertility after allogeneic uterus transplantation

Mats BrännströmShamima N. AkhiCesar Diaz-garciaCesar Diaz-garciaAntonio PellicerAnn Wallin

subject

Graft RejectionMaleInfertilitymedicine.medical_specialtymedia_common.quotation_subjectmedicine.medical_treatmentUterusFertilityTacrolimusRats Sprague-DawleyAnimal modelPregnancyUterus transplantationmedicineAnimalsTransplantation Homologousmedia_commonGynecologyPregnancyurogenital systembusiness.industryUterusObstetrics and GynecologyImmunosuppressionGeneral Medicinemedicine.diseaseRatsTransplantationFertilitysurgical procedures operativemedicine.anatomical_structureRats Inbred LewFemalebusinessInfertility FemaleImmunosuppressive Agents

description

Uterus transplantation may become the first available treatment for uterine factor infertility, which is due to the absence or malfunction of the uterus. Here we describe for the first time pregnancy after allogeneic uterus transplantation, as a proof of concept of uterine function in a transplanted uterus in a standardized animal model (rat) under immunosuppression.

yearjournalcountryeditionlanguage
2010-10-01Acta Obstetricia et Gynecologica Scandinavica
https://doi.org/10.3109/00016349.2010.520688