Breast Cancer Organoids Model Patient-Specific Response to Drug Treatment

6533b7d4fe1ef96bd126294d

RESEARCH PRODUCT

Breast Cancer Organoids Model Patient-Specific Response to Drug Treatment

Cristina Bottin Alessandro Zannini Alessandro Zannini Stefan Schoeftner Stefan Schoeftner Deborah Bonazza Marina Bortul Valeria Cancila Mariangela Santorsola Mariangela Santorsola Fabrizio Zanconati Giannino Del Sal Giannino Del Sal Elena Campaner Elena Campaner Claudio Tripodo

subject

0301 basic medicine Cancer Research Mechanotransduction Breast cancer; Dasatinib; Drug testing; Heterogeneity; Mechanotransduction; Patient‐derived tumor organoids; Statin; YAP Patient‐derived tumor organoid Cell Dasatinib Drug resistance Settore MED/08 - Anatomia Patologica Biology lcsh:RC254-282 Article 03 medical and health sciences Breast cancer 0302 clinical medicine Breast cancer breast cancer medicine Organoid Settore MED/05 - Patologia Clinica dasatinib drug testing mechanotransduction patient-derived tumor organoids Genetic heterogeneity statin Statin Drug testing Breast cancer Dasatinib Drug testing Drug testing Heterogeneity Patient‐derived tumor organoids Statin YAP medicine.disease lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens In vitro Dasatinib 030104 developmental biology medicine.anatomical_structure Oncology Cell culture 030220 oncology & carcinogenesis Cancer research Patient‐derived tumor organoids YAP Heterogeneity heterogeneity medicine.drug

description

Tumor organoids are tridimensional cell culture systems that are generated in vitro from surgically resected patients&rsquo

year	journal	country	edition	language
2020-12-01	Cancers

10.3390/cancers12123869 http://dx.doi.org/10.3390/cancers12123869

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